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Oncogene, ISSN 1476-5594, 04/2017, Volume 36, Issue 34, pp. 4887 - 4900
Our recent perplexing findings that polyploid giant cancer cells (PGCCs) acquired embryonic-like stemness and were capable of tumor initiation raised two important unanswered questions... 
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Paclitaxel - pharmacology | Neoplastic Stem Cells - drug effects | Giant Cells - drug effects | Humans | Ovarian Neoplasms - pathology | Carcinogenesis - metabolism | Blastomeres - drug effects | Blastomeres - metabolism | Neoplastic Stem Cells - metabolism | Female | Ovarian Neoplasms - metabolism | Cell Differentiation - physiology | Ovarian Neoplasms - drug therapy | Neoplastic Stem Cells - physiology | Polyploidy | Giant Cells - metabolism | Blastomeres - pathology | Carcinogenesis - drug effects | Carcinogenesis - pathology | Drug Resistance, Neoplasm - genetics | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Embryonic Stem Cells - pathology | Cell Line, Tumor | Signal Transduction - physiology | Giant Cells - pathology | Cellular signal transduction | Research | Cell differentiation | Cancer cells | Blastomeres | Senescence | Carcinoma | Mesenchyme | Mitosis | Oct-4 protein | Embryo cells | Benign | Compaction | Cytokinesis | Embryos | Spheroids | Ovarian cancer | Yes-associated protein | Chemotherapy | Developmental stages | Somatic cells | Paclitaxel | Stem cells | Giant cells | Tumorigenesis | Budding | Cancer | Tumors | Index Medicus | Original
Journal Article
Journal of lipid research, ISSN 0022-2275, 2017, Volume 58, Issue 6, pp. 1100 - 1113
.... Here, we show that Angptl4 mice fed a diet rich in trans FAs develop numerous lipid-filled giant cells in their MLNs, yet do not have elevated serum amyloid... 
Nutrition, Metabolism and Genomics | Chair Nutrition Metabolism and Genomics | HNE Voeding, Metabolisme en Genomics | VLAG | Voeding, Metabolisme en Genomica | HNE Nutrition, Metabolism and Genomics | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Lymph Nodes - pathology | Giant Cells - drug effects | Trans Fatty Acids - adverse effects | Foam Cells - cytology | Foam Cells - drug effects | Chylous Ascites - pathology | Peritonitis - pathology | Liver - drug effects | Lymph Nodes - drug effects | Foam Cells - pathology | Dietary Fats - adverse effects | Acute-Phase Proteins - metabolism | Liver - metabolism | Mice, Inbred C57BL | Peritonitis - metabolism | Chylous Ascites - chemically induced | Mesentery | Peritonitis - chemically induced | Lymph Nodes - cytology | Angiopoietin-like 4 Protein - deficiency | Chylous Ascites - metabolism | Animals | RAW 264.7 Cells | Mice | Giant Cells - pathology | Lymphatic system | Angiopoietin | Coronary artery | Dyslipidemia | Cardiovascular disease | Lipids | Triglycerides | Inflammation | Palmitic acid | Macrophages | Lymph nodes | Feeding | Cell activation | Haptoglobin | Protein folding | Arteriosclerosis | Rodents | Amyloid | Giant cells | Ascites | Heart diseases | Index Medicus | atherosclerosis | unfolded protein response | inflammation | angiopoietin-like 4 | macrophage foam cells | lipotoxicity
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 03/2012, Volume 109, Issue 13, pp. 5040 - 5045
Journal Article
PloS one, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e59418 - e59418
Cell-in-cell structures refer to a unique phenomenon that one living cell enters into another living cell intactly, occurring between homotypic tumor cells or tumor... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Communication - immunology | Stem Cells - immunology | Mitosis | Humans | Aneuploidy | Hepatocytes - pathology | Killer Cells, Lymphokine-Activated - pathology | Killer Cells, Natural - pathology | Killer Cells, Natural - immunology | Cell Differentiation | B-Lymphocytes - pathology | T-Lymphocytes - pathology | Tumor Cells, Cultured | Carcinoma - pathology | Carcinoma - immunology | Hepatocytes - immunology | Cell Transformation, Neoplastic - immunology | Killer Cells, Lymphokine-Activated - immunology | Animals | B-Lymphocytes - immunology | Giant Cells - immunology | Neoplasms - immunology | Stem Cells - pathology | T-Lymphocytes - immunology | Mice | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Giant Cells - pathology | Surveys | Killer cells | B cells | Stem cells | Cell culture | Biotechnology | Animal models | Carcinoma | Laboratories | Cytology | Stem cell transplantation | Cytotoxicity | Cannibalism | Tissues | Nuclei | Hepatitis | Immunology | Lymphocytes | Etiology | Physiology | Life sciences | Trends | Immune system | Antigens | Lymphokine-activated killer cells | Tumor cells | Melanoma | Inflammation | Shielding | Tumor cell lines | Monocytes | Hospitals | Surveillance | Lymphocytes B | Cells (biology) | Nuclei (cytology) | Tumors | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Journal Article
Annals of the rheumatic diseases, ISSN 0003-4967, 07/2014, Volume 73, Issue 7, pp. 1388 - 1392
Background Positron emission tomography (PET) scan is emerging as a promising imaging technique to detect large-vessel inflammation in giant cell arteritis (GCA... 
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Prospective Studies | Area Under Curve | Humans | Middle Aged | Temporal Arteries - pathology | Giant Cell Arteritis - pathology | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Case-Control Studies | Multimodal Imaging | Sensitivity and Specificity | Aged, 80 and over | Female | Subclavian Artery - diagnostic imaging | Radiopharmaceuticals | Aorta - diagnostic imaging | Giant Cell Arteritis - immunology | Arteries - pathology | Giant Cell Arteritis - diagnostic imaging | Carotid Arteries - diagnostic imaging | Femoral Artery - diagnostic imaging | Biopsy | Iliac Artery - diagnostic imaging | Interleukin-6 - immunology | Fluorodeoxyglucose F18 | ROC Curve | Aged | Arteries - diagnostic imaging | Acute-Phase Proteins - immunology | Axillary Artery - diagnostic imaging | Usage | Care and treatment | PET imaging | Inflammation | Giant cell arteritis | Diagnosis | Health aspects | Medical imaging | Nuclear magnetic resonance--NMR | Laboratories | Rodents | Coronary vessels | Atherosclerosis | Colonies & territories | Carotid arteries | Veins & arteries | Abdomen | Index Medicus | Case studies | Arteritis de cèl·lules gegants | Càncer | Inflamació | Estudi de casos | Single-photon emission computed tomography | Tomografia computada per emissió de fotó simple | Cancer
Journal Article