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Journal of Periodontology, ISSN 0022-3492, 08/2013, Volume 84, Issue 8, pp. 1145 - 1157
Background: Simvastatin is a cholesterol‐lowering drug whose pleiotropic effects may have a therapeutic impact on bone. This study evaluates the effect of... 
hydroxymethylglutaryl‐CoA reductase inhibitors | inflammation | Alveolar bone loss | periodontitis | Inflammation | Hydroxymethylglutaryl-CoA reductase inhibitors | Periodontitis | OVARIECTOMIZED RATS | STATINS | IN-VITRO | METABOLISM | DENTISTRY, ORAL SURGERY & MEDICINE | NITRIC-OXIDE | hydroxymethylglutaryl-CoA reductase inhibitors | MEVALONATE PATHWAY | KAPPA-B LIGAND | PROTEIN PRENYLATION | Interleukin-1beta - drug effects | Simvastatin - therapeutic use | Bone Morphogenetic Protein 2 - drug effects | Rats, Wistar | Matrix Metalloproteinase 8 - drug effects | Alveolar Bone Loss - prevention & control | Receptor Activator of Nuclear Factor-kappa B - drug effects | RANK Ligand - drug effects | Malondialdehyde - analysis | Alanine Transaminase - drug effects | Gingiva - drug effects | Glutathione - drug effects | Anti-Inflammatory Agents - therapeutic use | Female | Osteoprotegerin - drug effects | Interleukin-10 - analysis | Nitrates - analysis | Peroxidase - drug effects | Matrix Metalloproteinase 1 - drug effects | Nitric Oxide Synthase Type II - drug effects | Rats | Aspartate Aminotransferases - drug effects | Alkaline Phosphatase - drug effects | Periodontitis - prevention & control | Antioxidants - therapeutic use | Animals | Tumor Necrosis Factor-alpha - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Nitrites - analysis | Oxidative Stress - drug effects
Journal Article
Microbiology and Immunology, ISSN 0385-5600, 06/2019, Volume 63, Issue 6, pp. 213 - 222
Hinokitiol, a component of the essential oil isolated from Cupressaceae, possesses antibacterial and antifungal activities and has been used in oral care... 
antibacterial agent | Streptococcus pneumonia | hinokitiol | CELLS | MECHANISM | MICROBIOLOGY | COLONIZATION | TROPOLONE | IMMUNOLOGY | DECOLONIZATION | ADHESION | GROWTH | AGGREGATIBACTER-ACTINOMYCETEMCOMITANS | STAPHYLOCOCCUS-AUREUS | THUJAPLICIN | Cell Survival - drug effects | Streptococcus pneumoniae - drug effects | Streptococcus pyogenes - drug effects | Prevotella intermedia - drug effects | Epithelial Cells - drug effects | Humans | Methicillin-Resistant Staphylococcus aureus - drug effects | Bacteria - drug effects | Tropolone - analogs & derivatives | Streptococcus sobrinus - drug effects | Cell Line, Tumor - drug effects | Streptococcus mutans - drug effects | Tropolone - pharmacology | Fusobacterium nucleatum - drug effects | Microbial Sensitivity Tests | Monoterpenes - pharmacology | Mouth - microbiology | Bacteria - classification | Anti-Bacterial Agents - pharmacology | Aggregatibacter actinomycetemcomitans - drug effects | Staphylococcus aureus - drug effects | Porphyromonas gingivalis - drug effects | Methicillin | Drug resistance in microorganisms | Pneumonia | Bacterial pneumonia | Oral hygiene products | Bacteria | Dentifrices | Fungicides | Toxicity | Essential oils | Epithelial cells | Cytotoxicity | Pharynx | Endothelial cells | Streptococcus infections | Oral cavity | Streptococcus | Antibiotics | Fibroblasts | Antibacterial activity | Gingiva | Umbilical vein | Strains (organisms)
Journal Article
Dental Materials, ISSN 0109-5641, 2011, Volume 28, Issue 2, pp. 179 - 188
Abstract Objectives We aimed to achieve detailed biomaterials characterization of a drug delivery system for local periodontitis treatment based on electrospun... 
Advanced Basic Science | Dentistry | Dental materials | Polymeric fibers | Periodontitis | Polylactide | Electrospun fibers | Metronidazole | Drug delivery system | Biomaterials | ANTIBIOTICS | MATERIALS SCIENCE, BIOMATERIALS | EFFICACY | SUSCEPTIBILITY | ANTIBACTERIAL | AMOXICILLIN | DELIVERY | PERIODONTOPATHOGENIC BACTERIA | DENTISTRY, ORAL SURGERY & MEDICINE | AGENTS | Drug Delivery Systems - instrumentation | Anti-Infective Agents - pharmacology | Biocompatible Materials - chemistry | Humans | Chromatography, High Pressure Liquid | Fusobacterium nucleatum - drug effects | Biocompatible Materials - toxicity | Biocompatible Materials - chemical synthesis | Gingiva - drug effects | Time Factors | Spectrometry, X-Ray Emission | Surface Properties | Polyesters - chemical synthesis | Aggregatibacter actinomycetemcomitans - drug effects | Diffusion | Cell Survival - drug effects | Microscopy, Electron, Scanning | Electrochemical Techniques | Microbial Viability - drug effects | Metronidazole - administration & dosage | Cells, Cultured | Materials Testing | Cell Adhesion - drug effects | Polyesters - toxicity | Absorbable Implants | Metronidazole - pharmacology | Polyesters - chemistry | Anti-Infective Agents - administration & dosage | Periodontitis - drug therapy | Fibroblasts - drug effects | Gingiva - cytology | Calorimetry, Differential Scanning | Delayed-Action Preparations | Porphyromonas gingivalis - drug effects | Drugs | Drug delivery systems | Biological products | Vehicles | Fibers | Mats | Electrospinning | Bacteria | Strain
Journal Article
Journal Article
Journal of Periodontal Research, ISSN 0022-3484, 02/2013, Volume 48, Issue 1, pp. 66 - 73
Background and Objective:  Short‐chain fatty acids, such as butyric acid and propionic acid, are metabolic by‐products generated by periodontal microflora such... 
periodontal pathogen | short‐chain fatty acid | butyrate | cell cycle | periodontitis | reactive oxygen species | Short-chain fatty acid | Reactive oxygen species | Periodontitis | Periodontal pathogen | Cell cycle | Butyrate | CANCER-CELLS | short-chain fatty acid | ORAL KERATINOCYTES | DNA-DAMAGE | CHRONIC PERIODONTITIS | IN-VITRO | EPITHELIAL-CELLS | DENTISTRY, ORAL SURGERY & MEDICINE | CREVICULAR FLUID | SODIUM-BUTYRATE | CARBOXYLIC-ACID CONCENTRATION | DENTAL-PULP CELLS | CDC2 Protein Kinase | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Butyrates - pharmacology | Coloring Agents | Humans | cdc25 Phosphatases - drug effects | Cyclin B - drug effects | Flow Cytometry | G2 Phase Cell Cycle Checkpoints - drug effects | Gingiva - drug effects | Cell Culture Techniques | Cyclin-Dependent Kinases | Cell Survival - drug effects | M Phase Cell Cycle Checkpoints - drug effects | Fluoresceins | Cell Shape - drug effects | Cyclin B1 - drug effects | Propidium | Fluorescein-5-isothiocyanate | Fibroblasts - drug effects | Gingiva - cytology | Butyrates - toxicity | Resting Phase, Cell Cycle - drug effects | Cell Proliferation - drug effects | Fibroblasts - cytology | Cell Cycle - drug effects | G1 Phase Cell Cycle Checkpoints - drug effects | Fluorescent Dyes | Proteins | Medical colleges | RNA | Analysis | Genes | Esters | Saturated fatty acids | Index Medicus | Dentistry
Journal Article
Journal of Dental Research, ISSN 0022-0345, 6/2013, Volume 92, Issue 6, pp. 518 - 523
Journal Article
Journal of Periodontal Research, ISSN 0022-3484, 08/2015, Volume 50, Issue 4, pp. 423 - 433
Journal Article
Journal of Oral Pathology & Medicine, ISSN 0904-2512, 03/2015, Volume 44, Issue 3, pp. 214 - 221
Journal Article
Molecules, ISSN 1420-3049, 05/2015, Volume 20, Issue 5, pp. 9344 - 9357
Journal Article
Journal of Dental Research, ISSN 0022-0345, 8/2013, Volume 92, Issue 8, pp. 735 - 739
Oxidative stress is associated with age-related reactions. The anti-oxidative effects of a reduced form of co-enzyme Q10 (rCoQ10) suppress oxidative stress,... 
coenzyme Q10 | aging | preclinical drug evaluation | inflammasomes | periodontium | oxidative stress | RAT PERIODONTITIS | MODEL | LEVEL | SALIVARY | DAMAGE | ANTIOXIDANT | INFLAMMATION | DENTISTRY, ORAL SURGERY & MEDICINE | STRESS | Interleukin-1beta - drug effects | Isoenzymes - analysis | Deoxyguanosine - blood | Age Factors | NLR Family, Pyrin Domain-Containing 3 Protein | Rats, Inbred F344 | Aging - drug effects | Tartrate-Resistant Acid Phosphatase | Alveolar Process - drug effects | Actins - drug effects | Male | Deoxyguanosine - analysis | Vitamins - pharmacology | Ubiquinone - pharmacology | Gingiva - pathology | Gingiva - drug effects | Inflammasomes - drug effects | Ubiquinone - blood | Electron Transport Chain Complex Proteins - pharmacology | Periodontium - pathology | Models, Animal | Periodontium - drug effects | Cytoskeletal Proteins - drug effects | Deoxyguanosine - analogs & derivatives | Carrier Proteins | DNA Damage - drug effects | Acid Phosphatase - analysis | Receptors, Cytoplasmic and Nuclear - drug effects | Ubiquinone - analogs & derivatives | Alveolar Process - pathology | Rats | Antioxidants - pharmacology | Random Allocation | Animals | Apoptosis Regulatory Proteins | Caspase 1 - drug effects | CARD Signaling Adaptor Proteins | Oxidative Stress - drug effects | Osteoclasts - drug effects | NF-kappa B - drug effects
Journal Article
Journal of Dentistry, ISSN 0300-5712, 2013, Volume 41, Issue 10, pp. 881 - 891
Abstract Objectives The objectives of this study were to investigate: (1) the antibacterial activity of two antibacterial monomers, dimethylaminododecyl... 
Dentistry | Antibacterial activity | Cytotoxicity | Human fibroblasts | Time-kill | Oral bacteria | Quaternary ammonium methacrylate | Time-kill Human fibroblasts | STREPTOCOCCUS-MUTANS | DENTIN BOND STRENGTH | ENTEROCOCCUS-FAECALIS | SILVER NANOPARTICLES | ORAL PATHOGENS | IN-VITRO | RESIN COMPOSITE | CALCIUM-PHOSPHATE | DENTISTRY, ORAL SURGERY & MEDICINE | INFECTIVE ENDOCARDITIS | QUATERNARY AMMONIUM DIMETHACRYLATE | Enterococcus faecalis - drug effects | Quaternary Ammonium Compounds - toxicity | Humans | Bacteria - drug effects | Lactobacillus acidophilus - drug effects | Prevotella melaninogenica - drug effects | Gingiva - drug effects | Streptococcus sanguis - drug effects | Time Factors | Methacrylates - pharmacology | Methacrylates - chemical synthesis | Anti-Bacterial Agents - toxicity | Cell Culture Techniques | Microbial Viability - drug effects | Actinomyces - drug effects | Cells, Cultured | Streptococcus mutans - drug effects | Anti-Bacterial Agents - chemical synthesis | Mouth - microbiology | Fibroblasts - drug effects | Gingiva - cytology | Anti-Bacterial Agents - pharmacology | Quaternary Ammonium Compounds - chemical synthesis | Staphylococcus aureus - drug effects | Methacrylates - toxicity | Porphyromonas gingivalis - drug effects | Quaternary Ammonium Compounds - pharmacology | Antibacterial agents | Cells | Studies | Bond strength | Microbiology | Bacteriology | oral bacteria | time-kill | human fibroblasts | quaternary ammonium methacrylate | cytotoxicity
Journal Article