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Cell stem cell, ISSN 1934-5909, 2017, Volume 20, Issue 6, pp. 785 - 800.e8
Journal Article
British journal of cancer, ISSN 1532-1827, 2017, Volume 116, Issue 11, pp. 1425 - 1435
Background: Several evidences suggest a marked angiogenic dependency in triple-negative breast cancer (TNBC) tumorigenesis and a potential sensitivity to... 
Angiogenesis | Hedgehog | GLI1 | TNBC | NVP-LDE225 | METASTASIS | BEVACIZUMAB | angiogenesis | VEGF | THROMBOSPONDIN-1 | TRANSDUCTION | ENDOGENOUS INHIBITOR | CELL CARCINOMA | OVEREXPRESSION | hedgehog | ONCOLOGY | GROWTH | Human Umbilical Vein Endothelial Cells | Neoplasm Transplantation | Bevacizumab - pharmacology | Zinc Finger Protein GLI1 - metabolism | Tissue Array Analysis | Coculture Techniques | Humans | Middle Aged | Hedgehog Proteins - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Triple Negative Breast Neoplasms - drug therapy | Vascular Endothelial Growth Factor Receptor-2 - genetics | Young Adult | Triple Negative Breast Neoplasms - chemistry | Transfection | MCF-7 Cells | Thrombospondin 1 - genetics | Aged, 80 and over | Adult | Female | Paclitaxel - administration & dosage | Zinc Finger Protein GLI1 - analysis | Pyridines - administration & dosage | Signal Transduction | Vascular Endothelial Growth Factor Receptor-2 - analysis | Zinc Finger Protein GLI1 - genetics | Gene Silencing | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Hedgehog Proteins - antagonists & inhibitors | Membrane Proteins | Animals | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mice, Nude | Neovascularization, Pathologic - drug therapy | Triple Negative Breast Neoplasms - metabolism | Biphenyl Compounds - administration & dosage | Aged | Cell Proliferation - drug effects | Mice | Neovascularization, Pathologic - metabolism | Thrombospondin 1 - metabolism | Endothelial Cells - drug effects | Translational Therapeutics
Journal Article
Journal Article
EMBO reports, ISSN 1469-221X, 08/2017, Volume 18, Issue 8, pp. 1318 - 1330
Journal Article
Oncotarget, 2017, Volume 8, Issue 46, pp. 81088 - 81097
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 10/2017, Volume 102, Issue 4, pp. 965 - 976
Journal Article
Cancer Research, ISSN 0008-5472, 08/2017, Volume 77, Issue 16, pp. 4448 - 4459
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2017, Volume 114, Issue 49, pp. E10532 - E10539
Tissue regeneration relies on adult stem cells (SCs) that possess the ability to self-renew and produce differentiating progeny. In an analogous manner, the... 
Stemness | Hedgehog | Primary cilia | EMT | ACTIVATION | HAIR FOLLICLE | primary cilia | MULTIDISCIPLINARY SCIENCES | stemness | TISSUE | SELF-RENEWAL | GLI1 | GLAND DEVELOPMENT | BREAST-CANCER CELLS | hedgehog | DIFFERENTIATION | EXPRESSION | Epithelial Cells - metabolism | Zinc Finger Protein GLI1 - metabolism | Vimentin - metabolism | Humans | Gene Expression Regulation, Neoplastic | Spheroids, Cellular - pathology | Hedgehog Proteins - metabolism | Epithelial-Mesenchymal Transition - genetics | Mammary Neoplasms, Experimental - metabolism | Zinc Finger E-box-Binding Homeobox 1 - genetics | Mammary Neoplasms, Experimental - genetics | Occludin - metabolism | Zinc Finger E-box-Binding Homeobox 1 - metabolism | Occludin - genetics | Hedgehog Proteins - genetics | Neoplastic Stem Cells - metabolism | Vimentin - genetics | HEK293 Cells | Mammary Neoplasms, Experimental - pathology | Neoplastic Stem Cells - pathology | Female | Zinc Finger Protein Gli2 - genetics | Cilia - pathology | Signal Transduction | Mammary Glands, Animal - pathology | Zinc Finger Protein GLI1 - genetics | Spheroids, Cellular - metabolism | Epithelial Cells - pathology | Mice, Transgenic | Mice, SCID | Cilia - metabolism | Zinc Finger Protein Gli2 - metabolism | Animals | Mammary Glands, Animal - metabolism | Cell Line, Tumor | Mice | Biological Sciences | PNAS Plus
Journal Article
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, ISSN 0893-3952, 11/2019, Volume 32, Issue 11, pp. 1617 - 1626
GLI1 fusions involving ACTB, MALAT1 and PTCH1 genes have been recently reported in a subset of malignant soft tissue tumors with characteristic monomorphic... 
amplification | soft tissue neoplasm | CDK4 | MDM2 | GLI1
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 03/2017, Volume 36, Issue 13, pp. 1849 - 1861
BRAF inhibitor (BRAFi) therapy for melanoma patients harboring the V600E mutation is initially highly effective, but almost all patients relapse within a few... 
TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | DRUG-RESISTANCE | MESENCHYMAL TRANSITION | CELL BIOLOGY | GROWTH-FACTOR-BETA | IN-VITRO | MEK INHIBITION | ONCOLOGY | PATHWAY | GENETICS & HEREDITY | BRAF INHIBITOR RESISTANCE | EXPRESSION | Zinc Finger Protein GLI1 - metabolism | Humans | Zinc Finger Protein Gli2 | Hedgehog Proteins - metabolism | Drug Resistance, Neoplasm | Gene Knockdown Techniques | Kruppel-Like Transcription Factors - metabolism | Melanoma - genetics | Zinc Finger Protein GLI1 - antagonists & inhibitors | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Melanoma - metabolism | Cell Survival - drug effects | Cellular Senescence - genetics | Gene Expression | Zinc Finger Protein GLI1 - genetics | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Care and treatment | Melanoma | Genetic aspects | Research | Transforming growth factors | Health aspects | Cancer | Signal transduction | Oncology | Transcription factors | Mutation | Index Medicus | Original
Journal Article