X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (518) 518
zinc finger protein gli3 (510) 510
index medicus (421) 421
mice (421) 421
gli3 (409) 409
humans (361) 361
nerve tissue proteins - genetics (287) 287
developmental biology (273) 273
kruppel-like transcription factors - genetics (251) 251
nerve tissue proteins - metabolism (227) 227
kruppel-like transcription factors - metabolism (213) 213
signal transduction (211) 211
sonic hedgehog (209) 209
expression (188) 188
female (188) 188
gene expression regulation, developmental (185) 185
mutation (184) 184
transcription factors - genetics (183) 183
mouse (180) 180
hedgehog proteins - metabolism (178) 178
male (174) 174
genetics & heredity (172) 172
cell biology (167) 167
kruppel-like transcription factors (159) 159
hedgehog proteins (147) 147
animal structures (142) 142
shh (136) 136
dna-binding proteins - genetics (133) 133
sonic-hedgehog (133) 133
zinc finger protein gli2 (132) 132
embryonic structures (130) 130
hedgehog proteins - genetics (126) 126
nerve tissue proteins (123) 123
gene (114) 114
transcription factors - metabolism (113) 113
zinc finger protein gli1 (112) 112
hedgehog (108) 108
xenopus proteins (103) 103
gene expression (102) 102
biochemistry & molecular biology (99) 99
phenotype (99) 99
repressor proteins (95) 95
article (94) 94
polydactyly - genetics (94) 94
genes (89) 89
genetic aspects (88) 88
research (88) 88
proteins (87) 87
mice, knockout (85) 85
mutations (82) 82
mice, transgenic (80) 80
vertebrate limb (80) 80
limb development (78) 78
morphogenesis (78) 78
transcription factors (75) 75
dna-binding proteins - metabolism (73) 73
trans-activators - metabolism (72) 72
molecular biology (71) 71
greig cephalopolysyndactyly syndrome (70) 70
in situ hybridization (70) 70
analysis (68) 68
mice, inbred c57bl (68) 68
signal transduction - physiology (68) 68
gli2 (67) 67
mice, mutant strains (67) 67
polydactyly (67) 67
trans-activators - genetics (67) 67
patched receptors (63) 63
molecular sequence data (62) 62
base sequence (60) 60
body patterning (60) 60
differentiation (60) 60
gene-expression (59) 59
signal transduction - genetics (58) 58
extremities - embryology (57) 57
homeodomain proteins - genetics (57) 57
activation (56) 56
floor plate (56) 56
neural-tube (56) 56
polarizing activity (56) 56
multidisciplinary sciences (55) 55
cubitus-interruptus (54) 54
hedgehog protein (54) 54
cancer (53) 53
genetics (53) 53
neurosciences (53) 53
syndrome (53) 53
trans-activators (53) 53
nerve tissue proteins - physiology (52) 52
growth (51) 51
proliferation (51) 51
abnormalities, multiple - genetics (50) 50
body patterning - genetics (50) 50
research article (50) 50
cell differentiation (49) 49
gli1 (47) 47
homeodomain proteins - metabolism (47) 47
cell proliferation (46) 46
cells, cultured (46) 46
kruppel-like transcription factors - physiology (46) 46
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Journal Article
Journal Article
03/2012
The Sonic hedgehog (Shh) signaling pathway plays a critical role in murine gastric development. When Shh is knocked out in the mouse embryonic stomach,... 
0369 | mouse | hedgehog pathway | 0307 | 0758 | gastric development | Gli3
Dissertation
Journal Article
Development, ISSN 0950-1991, 2009, Volume 136, Issue 24, pp. 4177 - 4185
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 01/2020, Volume 117, Issue 2, pp. 1090 - 1096
In the tetrapod limb, the digits (fingers or toes) are the elements most subject to morphological diversification in response to functional adaptations.... 
limb development | Gli3 thumb | MULTIDISCIPLINARY SCIENCES | HOXD GENES | Hox genes | COLLINEARITY | SHH | EVOLUTION | DOWNSTREAM | MICE | ABSENCE | PROTEINS | EXPRESSION | Adaptations | Limbs | Antagonism | Territory | Transcription | Morphology | Modulation | Gene regulation | Regulatory sequences | Gene expression | Gli3 protein
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 02/2002, Volume 16, Issue 4, pp. 421 - 426
The bHLH transcription factor dHAND is required for establishment of SHH signaling by the limb bud organizer in posterior mesenchyme, a step crucial to... 
Polarizing region | Alx4 | SHH signalling | DHAND | Gli3 | Limb development | BHLH TRANSCRIPTION FACTOR | HOXB-8 | ZONE | MOUSE | DEVELOPMENTAL BIOLOGY | ESTABLISHMENT | FEEDBACK LOOP | CELL BIOLOGY | INACTIVATION | GENETICS & HEREDITY | POLARIZING ACTIVITY | ZPA FORMATION | EXPRESSION | Repressor Proteins | Transcription Factors - deficiency | Vertebrates - embryology | Zinc Finger Protein Gli3 | Helix-Loop-Helix Motifs | DNA-Binding Proteins - deficiency | Extremities - embryology | Trans-Activators - physiology | Hedgehog Proteins | Feedback | Trans-Activators - genetics | Mesoderm - ultrastructure | Basic Helix-Loop-Helix Transcription Factors | Gene Expression Regulation, Developmental - physiology | Proteins - physiology | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Zinc Fingers | Morphogenesis - genetics | Intercellular Signaling Peptides and Proteins | Zebrafish Proteins | Nerve Tissue Proteins | Transcription Factors - genetics | Xenopus Proteins | DNA-Binding Proteins - genetics | Mice, Knockout | Kruppel-Like Transcription Factors | Proteins - genetics | Animals | Trans-Activators - deficiency | Mice | Morphogenesis - physiology | Hedgehogs | Analysis | Genetic research | Physiological aspects | Genetic aspects | Genetic transcription | Gene expression | Alx4 gene | Gli3 gene | dHAND gene | Sonic hedgehog protein | GLI3 protein | limb development | dHAND | Research Communication | SHH signaling | polarizing region
Journal Article
International journal of oncology, ISSN 1019-6439, 12/2018, Volume 53, Issue 6, pp. 2458 - 2472
Journal Article
Human mutation, ISSN 1059-7794, 2010, Volume 31, Issue 10, pp. 1142 - 1154
Journal Article
Cytogenetic and Genome Research, ISSN 1424-8581, 01/2018, Volume 153, Issue 2, pp. 56 - 65
GLI family zinc finger proteins are transcriptional effectors of the sonic hedgehog signaling pathway. GLI regulates gene expression and repression at various... 
Original Article | Greig cephalopolysyndactyly syndrome | GLI family zinc finger protein | Contiguous gene deletion syndrome | Culler-Jones syndrome | SNP array | Pallister-Hall syndrome | Sonic hedgehog pathway | MOUSE | HEDGEHOG | CELL BIOLOGY | SHH | HYPOPITUITARISM | PATHWAY | GENES | DISEASE | GENETICS & HEREDITY | MUTATIONS | SPECTRUM | PROTEINS | Chromosomes, Human, Pair 2 - ultrastructure | Chromosomes, Human, Pair 7 - ultrastructure | Sequence Deletion | Oligonucleotide Array Sequence Analysis | Humans | Nerve Tissue Proteins - deficiency | Child, Preschool | Acrocephalosyndactylia - genetics | Cleft Palate - genetics | Hedgehog Proteins - physiology | Hemangioma, Cavernous, Central Nervous System - genetics | Intellectual Disability - genetics | Chromosomes, Human, Pair 2 - genetics | Zinc Finger Protein Gli3 - deficiency | Zinc Finger Protein Gli2 - deficiency | Karyotyping | Nuclear Proteins - deficiency | Female | Nuclear Proteins - genetics | Abnormalities, Multiple - genetics | Zinc Finger Protein Gli2 - genetics | Glucose Intolerance - genetics | Nerve Tissue Proteins - physiology | Morphogenesis - genetics | Signal Transduction - genetics | Nerve Tissue Proteins - genetics | Zinc Finger Protein Gli3 - genetics | Syndrome | Zinc Finger Protein Gli3 - physiology | Dwarfism - genetics | Zinc Finger Protein Gli2 - physiology | Phenotype | Models, Biological | Adolescent | Nuclear Proteins - physiology | Chromosomes, Human, Pair 7 - genetics
Journal Article
Genes and Development, ISSN 0890-9369, 10/2008, Volume 22, Issue 19, pp. 2651 - 2663
Sonic hedgehog (Shh) signals via Gli transcription factors to direct digit number and identity in the vertebrate limb. We characterized the Gli-dependent... 
Sonic hedgehog | Morphogen | Gli | Limb | Cis-regulatory network | limb | CELLS | gli | GREMLIN EXPRESSION | cis-regulatory network | DEVELOPMENTAL BIOLOGY | GLI3 | FEEDBACK LOOP | CELL BIOLOGY | BUD | morphogen | EXON ARRAYS | SHH | IN-VIVO | GENETICS & HEREDITY | sonic hedgehog | TRANSCRIPTIONAL REPRESSOR | VERTEBRATE LIMB | Genomics | Zinc Finger Protein Gli3 | Hedgehog Proteins - physiology | Gene Regulatory Networks | Genetic Complementation Test | Extremities - embryology | Intercellular Signaling Peptides and Proteins - physiology | Chromatin Immunoprecipitation | Hedgehog Proteins - genetics | Female | Basic Helix-Loop-Helix Transcription Factors - physiology | Nerve Tissue Proteins - physiology | Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Signal Transduction | Intercellular Signaling Peptides and Proteins - genetics | Kruppel-Like Transcription Factors - physiology | Mice, Transgenic | Binding Sites - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Body Patterning - physiology | Pregnancy | Animals | Enhancer Elements, Genetic | Models, Biological | Mice | Body Patterning - genetics | Kruppel-Like Transcription Factors - genetics | Positive Regulatory Domain I-Binding Factor 1 | Analysis | Genetic aspects | Genetic transcription | Gene expression | Genetic regulation | DNA-ligand interactions | Extremities (Anatomy) | Research Paper
Journal Article
Journal Article
by Cao, T and Wang, CB and Yang, M and Wu, CQ and Wang, BL
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 07/2013, Volume 379, Issue 2, pp. 221 - 228
Anterioposterior vertebrate limb patterning is controlled by opposing action between Sonic Hedgehog (Shh) and the G1i3 transcriptional repressor. Unexpectedly,... 
BETA-TRCP | PHENOTYPE | DEVELOPMENTAL BIOLOGY | INDUCTION | Gli3 | GLI3 PROTEIN | Hedgehog | SHH | ACTIVATOR | FLOOR PLATE | Limb patterning | MICE | VERTEBRATE LIMB | GENE-FUNCTION
Journal Article
Developmental Biology, ISSN 0012-1606, 2007, Volume 305, Issue 2, pp. 460 - 469
Anterior–posterior (A/P) limb patterning in vertebrates is determined by the counteraction between the Sonic Hedgehog (Shh) and the Gli3 transcription factor.... 
Hedgehog | Limb patterning | Gli3 repressor | Gli3 activator |