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Journal of Clinical Investigation, ISSN 0021-9738, 08/2014, Volume 124, Issue 8, pp. 3364 - 3377
Stem cell-based regenerative therapy is a promising treatment for head and neck cancer patients that suffer from chronic dry mouth (xerostomia) due to salivary... 
MEDICINE, RESEARCH & EXPERIMENTAL | GLAND FUNCTION | MORPHOGENESIS | MARROW-DERIVED CELLS | GENE-EXPRESSION | SELF-RENEWAL | DIFFERENTIATION | EPITHELIAL PROGENITOR CELLS | HEMATOPOIETIC STEM | TRANSPLANTATION | FAMILY | Adult Stem Cells - physiology | Glial Cell Line-Derived Neurotrophic Factor - physiology | Cell Proliferation | Xerostomia - physiopathology | Humans | Cell Survival - genetics | Head and Neck Neoplasms - physiopathology | Male | Salivary Glands - physiology | Submandibular Gland - physiology | Spheroids, Cellular - cytology | Salivary Glands - cytology | Spheroids, Cellular - physiology | Salivary Glands - radiation effects | Female | Cell Differentiation | Adult Stem Cells - transplantation | Cell Survival - physiology | Adult Stem Cells - drug effects | Radiation Injuries - therapy | Cell Survival - drug effects | Cell Separation | Mice, Inbred C57BL | Glial Cell Line-Derived Neurotrophic Factor - genetics | Mice, Transgenic | Gene Expression - radiation effects | Glial Cell Line-Derived Neurotrophic Factor - administration & dosage | Recombinant Proteins - administration & dosage | Radiation Injuries - etiology | Submandibular Gland - radiation effects | Head and Neck Neoplasms - radiotherapy | Animals | Saliva - metabolism | Saliva - drug effects | Submandibular Gland - cytology | Xerostomia - therapy | Mice | Radiation Injuries - physiopathology | Xerostomia - etiology | Physiological aspects | Research | Salivary glands | Neurotrophic functions | Stem cells | Population | Kinases | Gene expression | Colleges & universities
Journal Article
Journal Article
Stem Cells and Development, ISSN 1547-3287, 04/2014, Volume 23, Issue 7, pp. 741 - 754
In future, adipose-derived stem cells (ASC) might be used to treat neurological disorders. In this study, the neurotrophic and angiogenic properties of human... 
Original Research Reports | MEDICINE, RESEARCH & EXPERIMENTAL | AXONAL REGENERATION | ROOT GANGLIA NEURONS | TRANSCRIPTION FACTOR-3 ATF3 | SENSORY NEURONS | CELL & TISSUE ENGINEERING | TRANSPLANTATION | C-JUN PHOSPHORYLATION | IN-VITRO | NEURITE OUTGROWTH | GROWTH-FACTOR | SCHWANN-CELLS | STROMAL CELLS | HEMATOLOGY | Brain-Derived Neurotrophic Factor - genetics | Spinal Cord - metabolism | Humans | Nerve Regeneration - physiology | Adipose Tissue - cytology | Adipocytes - cytology | Culture Media, Conditioned - pharmacology | JNK Mitogen-Activated Protein Kinases - metabolism | Neurons - cytology | Ganglia, Spinal - cytology | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | GAP-43 Protein - genetics | Vascular Endothelial Growth Factor A - genetics | Stem Cell Transplantation | Adipose Tissue - metabolism | Glial Cell Line-Derived Neurotrophic Factor - metabolism | Mesenchymal Stromal Cells - cytology | Adult | Brain-Derived Neurotrophic Factor - metabolism | Cell Differentiation | Neurons - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Spinal Cord - cytology | Activating Transcription Factor 3 - genetics | Biomarkers - metabolism | Mesenchymal Stromal Cells - drug effects | Gene Expression | GAP-43 Protein - metabolism | Glial Cell Line-Derived Neurotrophic Factor - genetics | Mesenchymal Stromal Cells - metabolism | Rats | Activating Transcription Factor 3 - metabolism | Cell Lineage - physiology | Angiopoietin-1 - genetics | Animals | Adipocytes - metabolism | Adipocytes - transplantation | Adipose Tissue - drug effects | Neovascularization, Physiologic | Ganglia, Spinal - metabolism | Adipose tissues | Nervous system diseases | Care and treatment | Prognosis | Physiological aspects | Development and progression | Research | Neovascularization | Gene expression | Risk factors | Basic Medicine | Neurosciences | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Neurovetenskaper
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2009, Volume 66, Issue 2, pp. 137 - 145
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 4, pp. 1523 - 1538
Ret signaling is critical for formation of the enteric nervous system (ENS) because Ret activation promotes ENS precursor survival, proliferation, and... 
PRECURSOR PROLIFERATION | MICE LACKING GDNF | IN-VITRO | TYROSINE KINASE | HIRSCHSPRUNG-DISEASE | SMALL-INTESTINE | DOPAMINERGIC-NEURONS | MYENTERIC PLEXUS | NEUROSCIENCES | DEVELOPMENTAL DISTURBANCES | NEURAL CREST CELLS | Cell Cycle - genetics | Enteric Nervous System - cytology | Proto-Oncogene Proteins c-ret - metabolism | Cell Proliferation | Myenteric Plexus - embryology | NADPH Dehydrogenase - metabolism | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Myenteric Plexus - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Neurogenesis - genetics | Cell Differentiation - genetics | Glial Cell Line-Derived Neurotrophic Factor - metabolism | Neurites - ultrastructure | Glial Cell Line-Derived Neurotrophic Factor - pharmacology | Neurogenesis - drug effects | Neurons - metabolism | Enteric Nervous System - metabolism | Mice, Inbred C57BL | Gene Expression Regulation, Developmental - drug effects | Glial Cell Line-Derived Neurotrophic Factor - genetics | Enteric Nervous System - embryology | Gastrointestinal Motility - genetics | Mice, Transgenic | Myenteric Plexus - cytology | Neurites - metabolism | Mice, Knockout | Animals | Cell Differentiation - drug effects | Stem Cells - drug effects | Esophagus - embryology | Mice | Esophagus - innervation | Proto-Oncogene Proteins c-ret - genetics
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1873 - 1885
Parkin and the glial cell line-derived neurotrophic factor (GDNF) receptor RET have both been independently linked to the dopaminergic neuron degeneration that... 
RET | MEDICINE, RESEARCH & EXPERIMENTAL | PINK1 | ACTIVATION | REGENERATION | DISEASE | MITOCHONDRIAL DYSFUNCTION | ALPHA | GENE-THERAPY | MECHANISMS | RAT MODEL | Glial Cell Line-Derived Neurotrophic Factor - physiology | Substantia Nigra - pathology | Dopaminergic Neurons - pathology | Adenosine Triphosphate - biosynthesis | Ubiquitin-Protein Ligases - physiology | Recombinant Fusion Proteins - metabolism | Proto-Oncogene Proteins c-ret - physiology | Parkinsonian Disorders - genetics | Exploratory Behavior | Cell Line | Glial Cell Line-Derived Neurotrophic Factor - deficiency | Signal Transduction | Glial Cell Line-Derived Neurotrophic Factor - genetics | Cell Size | Mice, Transgenic | Mitochondria - pathology | Disease Progression | Nerve Degeneration - pathology | Mice, Knockout | Anxiety - genetics | Rotarod Performance Test | Animals | Parkinsonian Disorders - pathology | NF-kappa B - physiology | Phosphatidylinositol 3-Kinases - physiology | Proto-Oncogene Proteins c-ret - deficiency | Ubiquitin-Protein Ligases - deficiency | Mice | Ubiquitin-Protein Ligases - genetics | Proto-Oncogene Proteins c-ret - genetics | Parkinson's disease | Neurons | Physiological aspects | Development and progression | Research | Protein kinases | Neurotrophic functions | Proteins | Hypotheses | Dopamine | Rodents | Morphology | Kinases | Neuroscience
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e80613
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 10/2008, Volume 28, Issue 8, pp. 1467 - 1479
Journal Article
Gene Therapy, ISSN 0969-7128, 03/2006, Volume 13, Issue 5, pp. 379 - 388
Journal Article