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ACS Nano, ISSN 1936-0851, 01/2019, Volume 13, Issue 1, pp. 97 - 113
The blood-brain barrier (BBB) selectively controls the passage of endogenous and exogenous molecules between systemic circulation and the brain parenchyma.... 
nanomedicine | xenograft model | glioblastoma | doxorubicin | drug delivery | VEGF | MATERIALS SCIENCE, MULTIDISCIPLINARY | DOXORUBICIN DELIVERY | TUMOR | CHEMISTRY, PHYSICAL | ISCHEMIA | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | P-GLYCOPROTEIN | TEMOZOLOMIDE | MALIGNANT GLIOMA | NANOPARTICLES | DISRUPTION | ENDOTHELIAL GROWTH-FACTOR | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2014, Volume 370, Issue 8, pp. 709 - 722
In patients with glioblastoma, the addition of bevacizumab to radiotherapy and temozolomide induction therapy and the use of bevacizumab maintenance therapy... 
CONCOMITANT RADIOCHEMOTHERAPY | MEDICINE, GENERAL & INTERNAL | PHASE-II TRIAL | RECURRENT GLIOBLASTOMA | CLINICAL-TRIALS | MALIGNANT GLIOMAS | QUALITY-OF-LIFE | RESPONSE ASSESSMENT CRITERIA | MULTIFORME | HIGH-GRADE GLIOMA | ENDOTHELIAL GROWTH-FACTOR | Dacarbazine - adverse effects | Dacarbazine - therapeutic use | Humans | Middle Aged | Induction Chemotherapy | Male | Glioblastoma - radiotherapy | Bevacizumab | Young Adult | Dacarbazine - analogs & derivatives | Aged, 80 and over | Angiogenesis Inhibitors - therapeutic use | Adult | Female | Brain Neoplasms - mortality | Brain Neoplasms - radiotherapy | Angiogenesis Inhibitors - adverse effects | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Kaplan-Meier Estimate | Combined Modality Therapy | Brain Neoplasms - drug therapy | Disease-Free Survival | Quality of Life | Aged | Glioblastoma - drug therapy | Glioblastoma - mortality | Dosage and administration | Research | Temozolomide | Drug therapy, Combination | Drug therapy | Glioblastoma multiforme | Nuclear magnetic resonance--NMR | Intravenous administration | Glucocorticoids | Brain cancer | Body weight | Glioblastoma | Radiation therapy | Survival | Patients | Quality of life | Vascular endothelial growth factor | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
PPAR Research, ISSN 1687-4757, 2016, Volume 2016, pp. 7175067 - 8
Glioblastoma multiforme (GBM) represents one of the most frequent malignant brain tumors. Current therapies do not provide real solutions to this pathology.... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | LIGANDS | GROWTH | GENES | PPAR-GAMMA | RECEPTOR | INHIBITS PROLIFERATION | DIFFERENTIATION | EXPRESSION | TUMORS | Drug therapy | Glioblastoma multiforme | Studies | Cell culture | Neurosciences | Morphology | Stem cells | Ligands | Chromosomes
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2014, Volume 370, Issue 8, pp. 699 - 708
Journal Article
Lancet Oncology, ISSN 1470-2045, 2014, Volume 15, Issue 9, pp. 943 - 953
Journal Article
Cancer Letters, ISSN 0304-3835, 2013, Volume 343, Issue 2, pp. 286 - 294
Highlights • Besides proteasomal degradation, Mcl-1 is also degraded by caspase cleavage. • Caspase-mediated Mcl-1 cleavage occurs at two highly conserved... 
Hematology, Oncology and Palliative Medicine | Mcl-1 | c-Jun | MEFs | Multiple myeloma | Glioblastoma | Apoptosis | C-Jun
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 768 - 776
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. To better understand how GBM evolves, we analyzed longitudinal genomic and... 
GENE FUSIONS | TGF-BETA | CANCER GENOMICS | LANDSCAPE | GLIOMA | GENETICS & HEREDITY | GENOMIC ALTERATIONS | MSH6 MUTATIONS | SEQUENCING DATA | BRAIN-TUMORS | TEMOZOLOMIDE | Cell Proliferation | Dacarbazine - therapeutic use | Genomics | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Neoplasm Recurrence, Local - drug therapy | Clonal Evolution - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Survival Rate | Brain Neoplasms - drug therapy | Mutation - genetics | Antineoplastic Agents, Alkylating - therapeutic use | Latent TGF-beta Binding Proteins - genetics | DNA Modification Methylases - genetics | Transforming Growth Factor beta - genetics | Glioblastoma - pathology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Glioblastoma - drug therapy | Longitudinal Studies | Molecular targeted therapy | Care and treatment | Gene mutations | Development and progression | Genetic aspects | Genetic transcription | Glioblastoma multiforme | Health aspects | Methods | Brain cancer | Genomes | Gene expression | Cancer therapies | Studies | Archives & records | DNA methylation | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 34, Issue 1, pp. 196 - 208