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Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12823 - 12828
Journal Article
Nature reviews. Cancer, ISSN 1474-1768, 2016, Volume 16, Issue 9, pp. 566 - 581
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 448 - 15
Few studies implicate immunoregulatory gene expression in tumor cells in arbitrating brain tumor progression. Here we show that fibrinogen-like protein 2... 
ACTIVATION | HOMEOSTASIS | COLONY-STIMULATING FACTOR | MICROENVIRONMENT | GM-CSF | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | TRAFFICKING | ANTIGEN-PRESENTING CELLS | ANTITUMOR-ACTIVITY | T-CELLS | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Neuroglia - pathology | Dendritic Cells - immunology | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | NF-kappa B - immunology | Dendritic Cells - pathology | Neoplastic Stem Cells - immunology | STAT Transcription Factors - immunology | CD4-Positive T-Lymphocytes - pathology | Antigens, CD - genetics | CD4-Positive T-Lymphocytes - immunology | Brain Neoplasms - immunology | Heterografts | Glioblastoma - genetics | Integrin alpha Chains - immunology | Neuroglia - immunology | Neoplastic Stem Cells - pathology | Cell Differentiation | Brain Neoplasms - mortality | Fibrinogen - immunology | Brain Neoplasms - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Mice, Transgenic | p38 Mitogen-Activated Protein Kinases - immunology | Tumor Burden | Fibrinogen - genetics | Disease Progression | STAT Transcription Factors - genetics | Animals | Glioblastoma - immunology | NF-kappa B - genetics | Glioblastoma - pathology | Survival Analysis | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Glioblastoma - mortality | Integrin alpha Chains - genetics | Cell proliferation | Brain | Brain tumors | Brain cancer | Glioblastoma | Differentiation (biology) | Stem cell transplantation | Cerebrospinal fluid | Kinases | Granulocyte-macrophage colony stimulating factor | Lymph nodes | Proteins | Cell activation | CD103 antigen | Glioma cells | Fibrinogen | Colony-stimulating factor | Inhibition | Stat1 protein | Fgl2 protein | NF-κB protein | Arbitration | Dendritic cells | Immunoregulation | Granulocyte-macrophage colony-stimulating factor | Tumor cells | Immunodeficiency | Cell differentiation | Gene expression | Low level | Drainage | Stem cells | Tumors
Journal Article
Neuro-oncology (Charlottesville, Va.), ISSN 1523-5866, 2010, Volume 12, Issue 11, pp. 1113 - 1125
Macrophages (MΦs)/microglia that constitute the dominant tumor-infiltrating immune cells in glioblastoma are recruited by tumor-secreted factors and are... 
Immune suppression | Innate immunity | Cancer stem cells | Macrophages | Signal transducer and activator of transcription 3 | Microglia | ACTIVATION | TOLL-LIKE RECEPTOR | STAT3 | TGF-BETA SUPERFAMILY | signal transducer and activator of transcription 3 | CLINICAL NEUROLOGY | macrophages | GLIOBLASTOMA | innate immunity | ONCOLOGY | TUMOR-ASSOCIATED MACROPHAGES | cancer stem cells | SUPPRESSOR-CELLS | immune suppression | microglia | T-CELLS | PROGRESSION | Microglia - metabolism | Phosphorylation | Humans | Brain Neoplasms - pathology | Neoplastic Stem Cells - immunology | Brain Neoplasms - metabolism | Glioma - metabolism | Cell Movement - immunology | Signal Transduction - immunology | Brain Neoplasms - immunology | Flow Cytometry | Microglia - immunology | Transfection | Chemotactic Factors - metabolism | Neoplastic Stem Cells - metabolism | Glioma - pathology | Neoplastic Stem Cells - pathology | Macrophages - immunology | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Chemotactic Factors - immunology | Enzyme-Linked Immunosorbent Assay | Cell Separation | Cells, Cultured | Glioma - immunology | Blotting, Western | Immunity, Innate - immunology | Macrophages - metabolism | STAT3 Transcription Factor - immunology | Chemotaxis, Leukocyte - immunology | Cytokines - biosynthesis | Basic and Translational Investigations
Journal Article
Brain (London, England : 1878), ISSN 1460-2156, 2012, Volume 135, Issue 4, pp. 1042 - 1054
Peptides presented at the cell surface reflect the protein content of the cell; those on HLA class I molecules comprise the critical peptidome elements... 
peptidome | glioblastoma | tumour-infiltrating lymphocytes | tumour antigen | immunotherapy | AVIDITY | IDENTIFICATION | NEUROSCIENCES | CLINICAL NEUROLOGY | GLIOMA-CELL | GROWTH | CHONDROITIN SULFATE PROTEOGLYCAN | SELECTION | EXPRESSION | T-CELLS | PROGRESSION | TENASCIN-C | Oligonucleotide Array Sequence Analysis | Humans | Brain Neoplasms - pathology | Gene Expression Profiling | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Antigens, Neoplasm - chemistry | HLA-A Antigens - analysis | Antigens, CD - metabolism | Sequence Analysis, Protein | Brain Neoplasms - immunology | Flow Cytometry | Antigens, Neoplasm - therapeutic use | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Mass Spectrometry | Chromatography, Liquid | Cytokines - metabolism | Antigens, Neoplasm - immunology | Peptides - immunology | Glioblastoma - therapy | HLA-A Antigens - immunology | Glioblastoma - immunology | Glioblastoma - pathology | Brain Neoplasms - therapy | HLA-A Antigens - chemistry | CD8-Positive T-Lymphocytes - immunology | Antigen Presentation - physiology | Peptides - analysis | Receptor-Like Protein Tyrosine Phosphatases, Class 5 - metabolism | Immunogenicity | CD8 antigen | Immunotherapy | Glioblastoma | Data processing | Histocompatibility antigen HLA | Lymphocytes T | Vaccines | Cell surface | Immunological tolerance
Journal Article
Cancer immunology, immunotherapy, ISSN 1432-0851, 2012, Volume 62, Issue 1, pp. 125 - 135
This study evaluated the safety and immune responses to an autologous dendritic cell vaccine pulsed with class I peptides from tumor-associated antigens (TAA)... 
Cancer vaccine | Immunology | Medicine & Public Health | Glioblastoma | Oncology | Cancer Research | CTL | Epitopes | Cancer stem cells | Dendritic cell immunotherapy | GP100 | MARKER CD133 | IMMUNOLOGY | IDENTIFICATION | CANCER STEM-CELLS | MALIGNANT GLIOMA | CYTOTOXIC T-CELLS | ONCOLOGY | IMMUNOTHERAPY | GENE-EXPRESSION | PCR | ANTIGEN | Antigens, Neoplasm - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Brain Neoplasms - pathology | Histocompatibility Antigens Class I - immunology | Kaplan-Meier Estimate | Neoplastic Stem Cells - immunology | Male | Reverse Transcriptase Polymerase Chain Reaction | Epitopes - immunology | Glioblastoma - therapy | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Brain Neoplasms - immunology | Glioblastoma - immunology | Glioblastoma - pathology | Brain Neoplasms - therapy | Adult | Female | Aged | Brain Neoplasms - mortality | Dendritic Cells - transplantation | Glioblastoma - mortality | Rare earth metals | Care and treatment | Peptides | Dendritic cells | Immunotherapy | Stem cells | Clinical trials | Product development | Vaccines | T cells | Glioblastoma multiforme | Autografts | Brain stem | Brain tumors | Data processing | Leukocytes (mononuclear) | ErbB-2 protein | Survival | Leukapheresis | Glioma | Antigen (tumor-associated) | Interleukin 1 | Histocompatibility antigen HLA | Glycoprotein gp100 | Tumors | Original
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 3, pp. 997 - 1006
Glioblastoma multiforme (GBM) is a highly aggressive malignant brain tumor with fatal outcome. Tumor-associated macrophages and microglia (TAMs) have been... 
Checkpoint inhibition | Anti-CD47 | Immunotherapy | Glioblastoma | Microglia | STEM-CELLS | checkpoint inhibition | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | anti-CD47 | MOUSE | NEUROTOXICITY | glioblastoma | FRACTALKINE RECEPTOR | GENE | RESIDENT MICROGLIA | immunotherapy | INFILTRATING MONOCYTES | microglia | BRAIN | PROGRESSION | Brain Neoplasms - pathology | Neoplasm Proteins - immunology | Monocytes - immunology | CD47 Antigen - immunology | Neoplasms, Experimental - pathology | Signal Transduction - immunology | Brain Neoplasms - immunology | Microglia - immunology | Glioblastoma - genetics | Neoplasms, Experimental - immunology | Monocytes - pathology | Neoplasms, Experimental - genetics | Microglia - pathology | Receptors, Immunologic - immunology | Neoplasm Proteins - genetics | Macrophages - immunology | CD47 Antigen - genetics | Macrophages - pathology | Mice, Transgenic | Signal Transduction - genetics | Animals | Glioblastoma - immunology | Glioblastoma - pathology | Mice, Inbred NOD | Mice | Receptors, Immunologic - genetics | Phagocytosis | Brain | Transcription factors | Animal models | Transcription | Brain cancer | Brain tumors | Central nervous system | Effector cells | Inflammatory response | Macrophages | Blood | Immune system | Yolk | Therapeutic applications | Immunodeficiency | Inflammation | Glioblastoma multiforme | Cells | Yolk sac | Monocytes | Morphology | Disruption | Tumors | Biological Sciences | PNAS Plus
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2007, Volume 318, Issue 5853, pp. 1141 - 1143
Journal Article