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Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5853, pp. 1141 - 1143
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12823 - 12828
Journal Article
Neuro-Oncology, ISSN 1522-8517, 11/2010, Volume 12, Issue 11, pp. 1113 - 1125
Macrophages (MΦs)/microglia that constitute the dominant tumor-infiltrating immune cells in glioblastoma are recruited by tumor-secreted factors and are... 
Immune suppression | Innate immunity | Cancer stem cells | Macrophages | Signal transducer and activator of transcription 3 | Microglia | ACTIVATION | TOLL-LIKE RECEPTOR | TGF-BETA SUPERFAMILY | signal transducer and activator of transcription 3 | FACTOR-KAPPA-B | CLINICAL NEUROLOGY | macrophages | GLIOBLASTOMA | innate immunity | ONCOLOGY | TUMOR-ASSOCIATED MACROPHAGES | cancer stem cells | ANTITUMOR IMMUNITY | SUPPRESSOR-CELLS | immune suppression | microglia | T-CELLS | Microglia - metabolism | Phosphorylation | Humans | Brain Neoplasms - pathology | Neoplastic Stem Cells - immunology | Brain Neoplasms - metabolism | Glioma - metabolism | Cell Movement - immunology | Signal Transduction - immunology | Brain Neoplasms - immunology | Flow Cytometry | Microglia - immunology | Transfection | Chemotactic Factors - metabolism | Neoplastic Stem Cells - metabolism | Glioma - pathology | Neoplastic Stem Cells - pathology | Macrophages - immunology | STAT3 Transcription Factor - metabolism | Cytokines - immunology | Chemotactic Factors - immunology | Enzyme-Linked Immunosorbent Assay | Cell Separation | Cells, Cultured | Glioma - immunology | Blotting, Western | Immunity, Innate - immunology | Macrophages - metabolism | STAT3 Transcription Factor - immunology | Chemotaxis, Leukocyte - immunology | Cytokines - biosynthesis | Index Medicus | Basic and Translational Investigations
Journal Article
Brain, ISSN 0006-8950, 2012, Volume 135, Issue 4, pp. 1042 - 1054
Peptides presented at the cell surface reflect the protein content of the cell; those on HLA class I molecules comprise the critical peptidome elements... 
peptidome | glioblastoma | tumour-infiltrating lymphocytes | tumour antigen | immunotherapy | AVIDITY | IDENTIFICATION | NEUROSCIENCES | CLINICAL NEUROLOGY | GLIOMA-CELL | GROWTH | CHONDROITIN SULFATE PROTEOGLYCAN | SELECTION | EXPRESSION | T-CELLS | PROGRESSION | TENASCIN-C | Oligonucleotide Array Sequence Analysis | Humans | Brain Neoplasms - pathology | Gene Expression Profiling | Glial Fibrillary Acidic Protein - metabolism | RNA, Messenger - metabolism | Antigens, Neoplasm - chemistry | HLA-A Antigens - analysis | Antigens, CD - metabolism | Sequence Analysis, Protein | Brain Neoplasms - immunology | Flow Cytometry | Antigens, Neoplasm - therapeutic use | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Mass Spectrometry | Chromatography, Liquid | Cytokines - metabolism | Antigens, Neoplasm - immunology | Peptides - immunology | Glioblastoma - therapy | HLA-A Antigens - immunology | Glioblastoma - immunology | Glioblastoma - pathology | Brain Neoplasms - therapy | HLA-A Antigens - chemistry | CD8-Positive T-Lymphocytes - immunology | Antigen Presentation - physiology | Peptides - analysis | Receptor-Like Protein Tyrosine Phosphatases, Class 5 - metabolism | Index Medicus | Abridged Index Medicus | Immunogenicity | CD8 antigen | Immunotherapy | Glioblastoma | Data processing | Histocompatibility antigen HLA | Lymphocytes T | Vaccines | Cell surface | Immunological tolerance
Journal Article
Nature Communications, ISSN 2041-1723, 01/2019, Volume 10, Issue 1, pp. 448 - 15
Few studies implicate immunoregulatory gene expression in tumor cells in arbitrating brain tumor progression. Here we show that fibrinogen-like protein 2... 
ACTIVATION | HOMEOSTASIS | COLONY-STIMULATING FACTOR | MICROENVIRONMENT | GM-CSF | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | TRAFFICKING | ANTIGEN-PRESENTING CELLS | ANTITUMOR-ACTIVITY | T-CELLS | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Neuroglia - pathology | Dendritic Cells - immunology | Humans | Brain Neoplasms - pathology | Gene Expression Regulation, Neoplastic | NF-kappa B - immunology | Dendritic Cells - pathology | Neoplastic Stem Cells - immunology | STAT Transcription Factors - immunology | CD4-Positive T-Lymphocytes - pathology | Antigens, CD - genetics | CD4-Positive T-Lymphocytes - immunology | Brain Neoplasms - immunology | Heterografts | Glioblastoma - genetics | Integrin alpha Chains - immunology | Neuroglia - immunology | Neoplastic Stem Cells - pathology | Cell Differentiation | Brain Neoplasms - mortality | Fibrinogen - immunology | Brain Neoplasms - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Mice, Transgenic | p38 Mitogen-Activated Protein Kinases - immunology | Tumor Burden | Fibrinogen - genetics | Disease Progression | STAT Transcription Factors - genetics | Animals | Glioblastoma - immunology | NF-kappa B - genetics | Glioblastoma - pathology | Survival Analysis | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Glioblastoma - mortality | Integrin alpha Chains - genetics | Cell proliferation | Brain | Brain tumors | Brain cancer | Glioblastoma | Differentiation (biology) | Stem cell transplantation | Cerebrospinal fluid | Kinases | Granulocyte-macrophage colony stimulating factor | Lymph nodes | Proteins | Cell activation | CD103 antigen | Glioma cells | Fibrinogen | Colony-stimulating factor | Inhibition | Stat1 protein | Fgl2 protein | NF-κB protein | Arbitration | Dendritic cells | Immunoregulation | Granulocyte-macrophage colony-stimulating factor | Tumor cells | Immunodeficiency | Cell differentiation | Gene expression | Low level | Drainage | Stem cells | Tumors | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 03/2015, Volume 519, Issue 7543, pp. 366 - 369
After stimulation, dendritic cells(DCs) mature andmigrate to draining lymph nodes to induce immune responses(1). As such, autologous DCs generated ex vivo have... 
MALIGNANT GLIOMA | RESPONSES | IMMUNITY | MULTIDISCIPLINARY SCIENCES | HUMAN CYTOMEGALOVIRUS | VACCINATION | PERIPHERAL-BLOOD | MELANOMA-CELLS | MIP-1-ALPHA | TUMORS | T-CELLS | Phosphoproteins - immunology | Immunotherapy - methods | Viral Matrix Proteins - genetics | Chemokine CCL3 - immunology | Dendritic Cells - immunology | Humans | Substrate Specificity | Phosphoproteins - chemistry | CD4-Positive T-Lymphocytes - immunology | Cancer Vaccines - therapeutic use | Dendritic Cells - drug effects | Female | Lymph Nodes - drug effects | Tetanus Toxoid - pharmacology | Antigens, Neoplasm - immunology | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Tetanus Toxoid - therapeutic use | Survival Rate | Treatment Outcome | Lymph Nodes - immunology | Phosphoproteins - genetics | Lymph Nodes - cytology | Tetanus Toxoid - administration & dosage | Glioblastoma - therapy | Cancer Vaccines - immunology | Cell Movement - drug effects | Animals | Glioblastoma - immunology | Viral Matrix Proteins - chemistry | Glioblastoma - pathology | Dendritic Cells - cytology | Mice | Viral Matrix Proteins - immunology | Glioblastoma - drug therapy | CD4-Positive T-Lymphocytes - drug effects | Medical research | Dendritic cells | Physiological aspects | Medicine, Experimental | Vaccines | Research | Glioblastoma multiforme | Immunization | Lymphocytes | Medical prognosis | Clinical trials | Tetanus | Chemokines | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 12/2017, Volume 552, Issue 7685, pp. S64 - S66
The next generation of modified T-cell therapies is taking on solid tumours - but it's an uphill fight. 
Drug Costs | Receptors, Interleukin-13 - immunology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology | United States | Cell- and Tissue-Based Therapy - economics | Humans | Middle Aged | Male | Multiple Myeloma - immunology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | T-Lymphocytes - transplantation | United States Food and Drug Administration - legislation & jurisprudence | Allografts - transplantation | Drug Delivery Systems | Tissue Scaffolds | Multiple Myeloma - therapy | Neoplasms - therapy | Brain Neoplasms - immunology | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Time Factors | Cell Cycle Checkpoints - immunology | Child | Antigens, CD19 - immunology | Tumor Escape - immunology | GPI-Linked Proteins - immunology | Antigens, Neoplasm - immunology | Clinical Trials as Topic | Receptor Tyrosine Kinase-like Orphan Receptors - immunology | Immunotherapy - legislation & jurisprudence | Immunotherapy - adverse effects | Glioblastoma - therapy | Tumor Microenvironment - immunology | Animals | Glioblastoma - immunology | Cell Cycle Checkpoints - drug effects | Neoplasms - immunology | ErbB Receptors - immunology | Brain Neoplasms - therapy | Immunotherapy - economics | Lymphocyte Count | Cell Engineering | T-Lymphocytes - immunology | Mice | Nanoparticles - administration & dosage | Cell- and Tissue-Based Therapy - adverse effects | Cytotoxicity, Immunologic | Antigens | Research | T cells | Health aspects | Lymphatic system | Cytokines | Leukemia | Clinical trials | FDA approval | Patients | Cancer therapies | Blood | Proteins | Chemotherapy | Researchers | Lymphocytes | Lymphomas | Tumors | Index Medicus
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 1/2013, Volume 62, Issue 1, pp. 125 - 135
This study evaluated the safety and immune responses to an autologous dendritic cell vaccine pulsed with class I peptides from tumor-associated antigens (TAA)... 
Cancer vaccine | Immunology | Medicine & Public Health | Glioblastoma | Oncology | Cancer Research | CTL | Epitopes | Cancer stem cells | Dendritic cell immunotherapy | GP100 | MARKER CD133 | IMMUNOLOGY | IDENTIFICATION | CANCER STEM-CELLS | MALIGNANT GLIOMA | CYTOTOXIC T-CELLS | ONCOLOGY | IMMUNOTHERAPY | GENE-EXPRESSION | PCR | ANTIGEN | Antigens, Neoplasm - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Brain Neoplasms - pathology | Histocompatibility Antigens Class I - immunology | Kaplan-Meier Estimate | Neoplastic Stem Cells - immunology | Male | Reverse Transcriptase Polymerase Chain Reaction | Epitopes - immunology | Glioblastoma - therapy | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Brain Neoplasms - immunology | Glioblastoma - immunology | Glioblastoma - pathology | Brain Neoplasms - therapy | Adult | Female | Aged | Brain Neoplasms - mortality | Dendritic Cells - transplantation | Glioblastoma - mortality | Rare earth metals | Care and treatment | Peptides | Dendritic cells | Immunotherapy | Stem cells | Clinical trials | Product development | Vaccines | T cells | Glioblastoma multiforme | Index Medicus | Autografts | Brain stem | Brain tumors | Data processing | Leukocytes (mononuclear) | ErbB-2 protein | Survival | Leukapheresis | Glioma | Antigen (tumor-associated) | Interleukin 1 | Histocompatibility antigen HLA | Glycoprotein gp100 | Tumors | Original
Journal Article
Cancer Research, ISSN 0008-5472, 10/2007, Volume 67, Issue 20, pp. 9630 - 9636
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2010, Volume 16, Issue 2, pp. 474 - 485
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 05/2014, Volume 20, Issue 10, pp. 2684 - 2694
Journal Article