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Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 6, pp. 827 - 837
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e112945
The kynurenine pathway (KP) is the principal route of L-tryptophan (TRP) catabolism leading to the production of kynurenine (KYN), the neuroprotectants,... 
QUINOLINIC ACID | INHIBITION | METABOLISM | AMINOTRANSFERASE | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | T-CELL | TUMORAL IMMUNE RESISTANCE | TRYPTOPHAN DEGRADATION | IDO EXPRESSION | BRAIN | Immunohistochemistry | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Kynurenic Acid - blood | Gene Expression - drug effects | Humans | Kynurenine - biosynthesis | Brain Neoplasms - physiopathology | Picolinic Acids - blood | Quinolinic Acid - blood | Chromatography, High Pressure Liquid | Glial Fibrillary Acidic Protein - metabolism | Kynurenic Acid - metabolism | Carboxy-Lyases - genetics | Tryptophan - metabolism | Brain Neoplasms - metabolism | Picolinic Acids - metabolism | Antigens, CD - metabolism | Glioma - metabolism | Glioma - genetics | Kynurenine - blood | Tryptophan - blood | Carboxy-Lyases - metabolism | Tumor Cells, Cultured | Astrocytes - drug effects | Disaccharides | Cells, Cultured | Brain Neoplasms - genetics | Biosynthetic Pathways | Reverse Transcriptase Polymerase Chain Reaction | Glucuronates | Tryptophan Oxygenase - metabolism | Tryptophan Oxygenase - genetics | Antigens, Differentiation, Myelomonocytic - metabolism | Quinolinic Acid - metabolism | CD11b Antigen - metabolism | Glioma - physiopathology | Interferon-gamma - pharmacology | Astrocytes - metabolism | Tryptophan | Niacinamide | Methyl aspartate | Enzymes | Metabolites | Gliomas | Neuroprotection | Brain | Brain tumors | Brain cancer | Glioblastoma | Tryptophan 2,3-dioxygenase | Immunity | DNA repair | Picolinic acid | Rodents | Glioma cells | L-Tryptophan | Kynurenic acid | Quinolinic acid | Deoxyribonucleic acid--DNA | Pyridines | Medical research | Hydroxylase | Adenine | Kynurenine-oxoglutarate transaminase | NAD | Acids | γ-Interferon | Nicotinamide adenine dinucleotide | Catabolism | Nicotinamide | Interferon | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Cell metabolism, ISSN 1550-4131, 2013, Volume 18, Issue 5, pp. 726 - 739
Journal Article
NMR in biomedicine, ISSN 0952-3480, 2012, Volume 25, Issue 11, pp. 1234 - 1244
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2011, Volume 108, Issue 38, pp. 16062 - 16067
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2012, Volume 122, Issue 7, pp. 2454 - 2468
In inflammatory CNS conditions such as multiple sclerosis (MS), current options to treat clinical relapse are limited, and more selective agents are needed.... 
MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | MULTIPLE-SCLEROSIS | NEURITE OUTGROWTH | NITRIC-OXIDE SYNTHASE | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | VASCULAR-PERMEABILITY | ENDOTHELIAL GROWTH-FACTOR | HUMAN GLIOBLASTOMA-MULTIFORME | Membrane Glycoproteins - metabolism | Humans | Male | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Occludin | Brain - metabolism | Inflammation - metabolism | Nitric Oxide Synthase Type III - metabolism | Demyelinating Diseases | Multiple Sclerosis - metabolism | Interleukin-1beta - physiology | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Nuclear Proteins - metabolism | Permeability | Blood-Brain Barrier - metabolism | Membrane Glycoproteins - genetics | Membrane Proteins | Nerve Tissue Proteins - metabolism | Blood-Brain Barrier - pathology | Lymphocytes - pathology | Animals | Brain - pathology | Multiple Sclerosis - pathology | Mice | Primary Cell Culture | Vascular Endothelial Growth Factor A - physiology | Astrocytes - metabolism | Physiological aspects | Central nervous system diseases | Research | Blood-brain barrier | Vascular endothelial growth factor
Journal Article
Cancer cell, ISSN 1535-6108, 2015, Volume 28, Issue 5, pp. 569 - 581
Journal Article
Cell death & disease, ISSN 2041-4889, 2014, Volume 5, Issue 5, pp. e1212 - e1212
Oxidative stress serves as an important regulator of both apoptosis and metabolic reprogramming in tumor cells. Chaetocin, a histone methyltransferase... 
YAP | ATM | Metabolism | JNK | Glioblastoma | ROS | YES-ASSOCIATED PROTEIN | GLIOMA-CELLS | ACTIVATION | DNA-DAMAGE | CANCER | CELL BIOLOGY | GROWTH | KAPPA-B AXIS | metabolism | UP-REGULATION | GLIOBLASTOMA CELLS | Reactive Oxygen Species - metabolism | Ataxia Telangiectasia Mutated Proteins - metabolism | Apoptosis - drug effects | Humans | Brain Neoplasms - pathology | JNK Mitogen-Activated Protein Kinases - metabolism | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Glioma - genetics | Transfection | RNA Interference | Time Factors | Adenosine Triphosphate - metabolism | Glioma - pathology | Antineoplastic Agents - pharmacology | Brain Neoplasms - enzymology | Tumor Suppressor Proteins - metabolism | Glioma - enzymology | Pyruvate Kinase - metabolism | Lactic Acid - metabolism | Brain Neoplasms - genetics | Nuclear Proteins - metabolism | Phosphoproteins - genetics | Brain Neoplasms - drug therapy | Piperazines - pharmacology | Xenograft Model Antitumor Assays | p300-CBP Transcription Factors - metabolism | Tumor Protein p73 | Animals | Signal Transduction - drug effects | Tumor Burden - drug effects | Mice, Nude | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Glucose - metabolism | Cell Proliferation - drug effects | Mice | Enzyme Activation | Oxidative Stress - drug effects | Adaptor Proteins, Signal Transducing - metabolism | Hexokinase - metabolism | Glioma - drug therapy | Original
Journal Article
Cell death & disease, ISSN 2041-4889, 2018, Volume 9, Issue 10, pp. 990 - 17
Journal Article
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 13616
Journal Article