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International journal of nanomedicine, ISSN 1178-2013, 2018, Volume 13, pp. 5231 - 5248
Background: Mesenchymal stem cells (MSCs) possess inherent tropism towards tumor cells, and so have attracted increased attention as targeted-therapy vehicles for glioma treatment. Purpose... 
C6 cells | Drug targeting | Orthotopic glioma | Bmscs | Contralateral injection | EXOCYTOSIS | LUNG MELANOMA METASTASES | DRUG-DELIVERY | orthotopic glioma | NANOSCIENCE & NANOTECHNOLOGY | POLY(D,L-LACTIDE-CO-GLYCOLIDE) | PACLITAXEL | TEMOZOLOMIDE | drug targeting | MALIGNANT GLIOMA | PHARMACOLOGY & PHARMACY | GENE-THERAPY | contralateral injection | STROMAL CELLS | BMSCs | BRAIN | Paclitaxel - pharmacology | Nanoparticles - chemistry | Polylactic Acid-Polyglycolic Acid Copolymer | Adipogenesis - drug effects | Humans | Male | Drug Carriers | Drug Delivery Systems | Tissue Distribution | Endocytosis | Mesenchymal Stem Cells - cytology | Mesenchymal Stem Cells - drug effects | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Mesenchymal Stem Cells - metabolism | Lactic Acid - chemistry | Osteogenesis - drug effects | Nanoparticles - ultrastructure | Paclitaxel - therapeutic use | Rats, Sprague-Dawley | Cell Movement - drug effects | Animals | Polyglycolic Acid - chemistry | Cell Line, Tumor | Nanoparticles - administration & dosage | Kinetics | Cell Cycle - drug effects | Glioma - drug therapy | Nanoparticles | Chemotherapy | Gliomas | Cell death | Stem cells | Transplantation | Health aspects | Cancer | Quantum dots | Brain cancer | Radiation therapy | Artificial chromosomes | Cancer therapies | Molecular weight | Microscopy | Medical prognosis | Cell cycle | Polyvinyl alcohol | Gene therapy | Laboratory animals | Drug dosages | Tumors
Journal Article
PloS one, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e44603
Background: Glioma, including anaplastic astrocytoma and glioblastoma multiforme (GBM) are among the most commonly diagnosed malignant adult brain tumors. GBM... 
CELLS | GLIOBLASTOMA | PROTECTION | GLUCOSE | MULTIDISCIPLINARY SCIENCES | CONCOMITANT | CANCER-RISK | MALIGNANT GLIOMAS | 2-DEOXY-D-GLUCOSE | CHEMOTHERAPY | TEMOZOLOMIDE | Astrocytoma - radiotherapy | Neoplasm Transplantation | Body Weight | Dacarbazine - therapeutic use | Brain Neoplasms - pathology | Luminescence | Antineoplastic Agents, Alkylating - pharmacology | Male | Glioblastoma - radiotherapy | Glioma - radiotherapy | Astrocytoma - pathology | Glioma - pathology | Astrocytoma - drug therapy | Dacarbazine - analogs & derivatives | Brain Neoplasms - radiotherapy | Insulin-Like Growth Factor I - therapeutic use | Fasting | Mice, Inbred C57BL | Rats | Brain Neoplasms - drug therapy | Animals | Glioblastoma - pathology | Cell Line, Tumor | Mice | Blood Glucose - metabolism | Glioblastoma - drug therapy | Glioma - drug therapy | Chemotherapy | Gliomas | Blood sugar | Development and progression | Temozolomide | Radiotherapy | Health aspects | Cancer | Short term | Brain | Cell culture | Animal models | Insulin-like growth factor I | Brain tumors | Brain cancer | Glioblastoma | Insulin-like growth factors | Cancer therapies | Mimicry | Angiogenesis | Metabolites | Surgery | Glioma cells | DNA methylation | Bone marrow | Physiology | Drug dosages | Astrocytoma | Deoxyribonucleic acid--DNA | Sensitizing | Starvation | Cell survival | Tumor cells | Invasiveness | Melanoma | Radio | Radiation therapy | Metabolism | Insulin | Glioblastoma multiforme | Survival | Gerontology | Blood circulation | In vivo methods and tests | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 37, pp. 345 - 352
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 2014, Volume 15, Issue 6, pp. 10034 - 10051
.... Consequently, autophagy has generally been considered a prosurvival response. Many, if not most chemotherapeutic drugs and radiation also promote autophagy... 
Chemotherapy | Autophagy | Radiation | Apoptosis | MALIGNANT GLIOMA-CELLS | autophagy | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | ENDOPLASMIC-RETICULUM STRESS | chemotherapy | SYNERGISTIC AUGMENTATION | CYTOPROTECTIVE AUTOPHAGY | CHEMISTRY, MULTIDISCIPLINARY | PHOSPHORYLATION SITES | RADIATION-RESISTANCE | LUNG-CANCER | PI3K/AKT PATHWAY | radiation | BREAST-TUMOR CELLS | DOMAIN-CONTAINING PROTEIN-1 | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Apoptosis - radiation effects | Autophagy - radiation effects | Humans | Lung Neoplasms - metabolism | Brain Neoplasms - pathology | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Breast - metabolism | Glioblastoma - radiotherapy | Autophagy - drug effects | Brain Neoplasms - metabolism | Breast Neoplasms - metabolism | Brain - metabolism | Female | Glioblastoma - metabolism | Lung - radiation effects | Antineoplastic Agents - pharmacology | Lung - metabolism | Brain Neoplasms - radiotherapy | Breast - pathology | Breast - radiation effects | Lung - pathology | Brain - radiation effects | Brain Neoplasms - drug therapy | Breast Neoplasms - drug therapy | Brain - drug effects | Breast Neoplasms - radiotherapy | Animals | Breast - drug effects | Breast Neoplasms - pathology | Glioblastoma - pathology | Lung - drug effects | Brain - pathology | Glioblastoma - drug therapy | Cytotoxicity | Radiation therapy | Cancer therapies
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2016, Volume 67, pp. 130 - 140
Abstract Objectives Dose-finding trials are fundamental to develop novel drugs for children and adolescents with advanced cancer... 
Hematology, Oncology and Palliative Medicine | Innovative Therapies for Children with Cancer | Dose-finding trial | Prognostic factor | Phase I trial | Children | Adolescents | Survival | ONCOLOGY TRIALS | SCORE | VALIDATION | I CLINICAL-TRIALS | CONTEXT | PEDIATRIC PHASE-I | CENTER EXPERIENCE | ONCOLOGY | Osteosarcoma - drug therapy | Multivariate Analysis | Prognosis | Neuroectodermal Tumors, Primitive - drug therapy | Humans | Child, Preschool | Infant | Male | Neuroblastoma - mortality | Sarcoma, Ewing - mortality | Medulloblastoma - mortality | Ependymoma - drug therapy | Employment | Ependymoma - mortality | Sarcoma - mortality | Female | Rhabdomyosarcoma - drug therapy | Retrospective Studies | Child | Rhabdomyosarcoma - mortality | Schools | Osteosarcoma - mortality | Glioma - mortality | Neuroectodermal Tumors, Primitive - mortality | Europe | Proportional Hazards Models | Neoplasms - mortality | Therapies, Investigational | Survival Rate | Sarcoma - drug therapy | Neoplasms - drug therapy | Sarcoma, Ewing - drug therapy | Neuroblastoma - drug therapy | Adolescent | Medulloblastoma - drug therapy | Central Nervous System Neoplasms - drug therapy | Central Nervous System Neoplasms - mortality | Clinical Trials, Phase I as Topic | Glioma - drug therapy | Care and treatment | Patient outcomes | Children's hospitals | Oncology, Experimental | Clinical trials | Research | Health aspects | Cancer
Journal Article
International journal of radiation oncology, biology, physics, ISSN 0360-3016, 2011, Volume 81, Issue 1, pp. 126 - 134
Purpose To perform a comprehensive cognitive function (CF) assessment in patients who were relapse free after curative intent radiotherapy (RT... 
Radiology | Hematology, Oncology and Palliative Medicine | Squamous cell carcinoma of the head and neck | Chemotherapy | Neuropsychological testing | Radiotherapy | Cognitive dysfunction | PROPHYLACTIC CRANIAL IRRADIATION | ADJUVANT CHEMOTHERAPY | DRIVING PERFORMANCE | FOLLOW-UP | CELL LUNG-CANCER | BREAST-CANCER | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | NEUROCOGNITIVE FUNCTION | LOW-GRADE GLIOMA | QUALITY-OF-LIFE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Laryngeal Neoplasms - radiotherapy | Pharyngeal Neoplasms - radiotherapy | Cerebellum - radiation effects | Prospective Studies | Humans | Middle Aged | Male | Pharyngeal Neoplasms - drug therapy | Antineoplastic Agents - administration & dosage | Cognition - physiology | Laryngeal Neoplasms - drug therapy | Neoplasms, Squamous Cell - pathology | Carcinoma - drug therapy | Carcinoma - blood | Affect - physiology | Head and Neck Neoplasms - drug therapy | Cognition - drug effects | Neoplasms, Squamous Cell - blood | Head and Neck Neoplasms - pathology | Carcinoma, Squamous Cell | Neuropsychological Tests | Cognition Disorders - diagnosis | Memory Disorders - etiology | Hypopharyngeal Neoplasms - pathology | Quality of Life | Pharyngeal Neoplasms - pathology | Hypopharyngeal Neoplasms - drug therapy | Temporal Lobe - drug effects | Laryngeal Neoplasms - blood | Cerebellum - drug effects | Hypopharyngeal Neoplasms - blood | Cisplatin - administration & dosage | Feasibility Studies | Laryngeal Neoplasms - pathology | Squamous Cell Carcinoma of Head and Neck | Head and Neck Neoplasms - blood | Antineoplastic Agents - adverse effects | Cognition Disorders - etiology | Neoplasms, Squamous Cell - drug therapy | Neoplasms, Squamous Cell - radiotherapy | Female | Carcinoma - pathology | Cognition - radiation effects | Affect - drug effects | Pharyngeal Neoplasms - blood | Affect - radiation effects | Carcinoma - radiotherapy | Combined Modality Therapy - adverse effects | Head and Neck Neoplasms - radiotherapy | Hypopharyngeal Neoplasms - radiotherapy | Cisplatin - adverse effects | Aged | Combined Modality Therapy - methods | Temporal Lobe - radiation effects | Care and treatment | Squamous cell carcinoma | Cancer | BODY FLUIDS | HEAD | NERVOUS SYSTEM | RADIATION DOSES | MEDICINE | THERAPY | CEREBELLUM | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | COMBINED THERAPY | BRAIN | RADIOLOGY | BLOOD | NEOPLASMS | BIOLOGICAL MATERIALS | CENTRAL NERVOUS SYSTEM | STANDARD OF LIVING | CHEMOTHERAPY | NUCLEAR MEDICINE | ORGANS | DISEASES | DOSES | CARCINOMAS | NECK | DOSIMETRY | BODY | MATERIALS
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 22, pp. 5640 - 5650
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2005, Volume 352, Issue 10, pp. 987 - 996
Journal Article