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Clinical & Experimental Immunology, ISSN 0009-9104, 09/2015, Volume 181, Issue 3, pp. 518 - 527
The interaction between neutrophils and activation of alternative complement pathway plays a pivotal role in the pathogenesis of anti‐neutrophil cytoplasmic... 
neutrophil extracellular traps | complement | ANCA | vasculitis | alternative complement pathway | Complement | Vasculitis | Alternative complement pathway | Neutrophil extracellular traps | GLOMERULONEPHRITIS | ANTIBODY-ASSOCIATED VASCULITIS | PROTEIN C3 | DENDRITIC CELLS | DEPOSITION | IMMUNOLOGY | INHIBITION | DISEASE | ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODIES | GENERATION | Neutrophils - cytology | Complement Membrane Attack Complex - metabolism | Extracellular Traps - metabolism | Humans | Serum - drug effects | Complement C5a - metabolism | Immunoblotting | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - blood | Complement Membrane Attack Complex - immunology | Complement Activation - immunology | Antibodies, Antineutrophil Cytoplasmic - immunology | Serum - immunology | Antibodies, Antineutrophil Cytoplasmic - metabolism | Complement C3b - metabolism | Extracellular Traps - immunology | Complement Factor B - metabolism | Properdin - immunology | Extracellular Traps - drug effects | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - metabolism | Complement C3a - metabolism | Neutrophils - metabolism | Complement Activation - drug effects | Cells, Cultured | Neutrophils - immunology | Hot Temperature | Egtazic Acid - immunology | Microscopy, Confocal | Egtazic Acid - pharmacology | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - immunology | Complement Pathway, Alternative - drug effects | Complement Pathway, Alternative - immunology | Complement Factor B - immunology | Complement C3a - immunology | Complement C5a - immunology | Complement C3b - immunology | Properdin - metabolism | Index Medicus | Translational
Journal Article
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 57, pp. 42 - 52
Abstract Kidney involvement affects 40–60% of patients with lupus, and is responsible for significant morbidity and mortality. Using depletion approaches,... 
Allergy and Immunology | Lupus nephritis | Macrophages | SLE | Nephrotoxic serum nephritis (NTS) | SYSTEMIC-LUPUS-ERYTHEMATOSUS | RENAL MACROPHAGES | COLONY-STIMULATING FACTOR | FACTOR-I | IMMUNOLOGY | ANTI-DNA ANTIBODY | NEPHROTOXIC SERUM NEPHRITIS | MRL/LPR MICE | DISEASE | MURINE LUPUS | TWEAK/FN14 PATHWAY | Pyrimidines - immunology | Gene Expression - drug effects | Glomerulonephritis - prevention & control | Anisoles - pharmacology | Humans | Kidney - immunology | Matrix Metalloproteinase 9 - immunology | HMGB1 Protein - immunology | Anisoles - immunology | HMGB1 Protein - genetics | Proteinuria - prevention & control | Kidney - metabolism | Matrix Metalloproteinase 9 - metabolism | Flow Cytometry | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Matrix Metalloproteinase 9 - genetics | HMGB1 Protein - metabolism | Gene Expression - immunology | Antibodies - immunology | Kidney Glomerulus - metabolism | Mice, Inbred DBA | Macrophages - immunology | Disease Models, Animal | Rabbits | Kidney - drug effects | Proteinuria - immunology | Mice, Inbred C57BL | Glomerulonephritis - immunology | Lupus Nephritis - immunology | Kidney Glomerulus - pathology | Pyrimidines - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Macrophages - metabolism | Animals | Macrophages - drug effects | T-Lymphocytes - immunology | Kidney Glomerulus - immunology | Immunoglobulin G - metabolism | Lupus Nephritis - prevention & control | Lupus | Autoimmunity | Nephritis | Autoantibodies | Analysis | Mortality | Gene expression | Index Medicus | lupus nephritis | nephrotoxic serum nephritis (NTS)
Journal Article
American Journal of Kidney Diseases, ISSN 0272-6386, 2015, Volume 66, Issue 5, pp. 756 - 767
Background Kidney diseases associated with immunoglobulin M (IgM) monoclonal gammopathy are poorly described, with few data for patient outcomes and renal... 
Nephrology | tubular disorder | membranoproliferative glomerulonephritis | amyloidosis | kidney biopsy | cast nephropathy | Monoclonal gammopathy | renal response | Waldenström magroglobulinemia | Fanconi syndrome | B-cell lymphoproliferative disorder | IgM | MULTIPLE-MYELOMA | IMMUNOLOGICAL FEATURES | WALDENSTROMS MACROGLOBULINEMIA | RENAL SIGNIFICANCE | DEPOSITION DISEASE | Waldenstrom magroglobulinemia | HEAVY-CHAIN | INTERNATIONAL WORKSHOP | LIGHT-CHAIN AMYLOIDOSIS | UNDETERMINED SIGNIFICANCE | UROLOGY & NEPHROLOGY | NEPHROTIC SYNDROME | Lymphoma, B-Cell - complications | Humans | Middle Aged | Kidney Neoplasms - immunology | Lymphoproliferative Disorders - complications | Male | Lymphoproliferative Disorders - immunology | Immunoglobulin M - immunology | Waldenstrom Macroglobulinemia - pathology | Nephritis, Interstitial - pathology | Paraproteinemias - pathology | Waldenstrom Macroglobulinemia - complications | Amyloidosis - immunology | Lymphoma, B-Cell - immunology | Aged, 80 and over | Adult | Female | Amyloidosis - etiology | Retrospective Studies | Acute Kidney Injury - immunology | Kidney Neoplasms - complications | Acute Kidney Injury - etiology | Antibodies, Monoclonal - immunology | Paraproteinemias - immunology | Glomerulonephritis, Membranoproliferative - pathology | Amyloidosis - pathology | Acute Kidney Injury - pathology | Kidney Diseases - pathology | Nephrotic Syndrome - pathology | Paraproteinemias - complications | Kidney Diseases - immunology | Nephrotic Syndrome - immunology | Waldenstrom Macroglobulinemia - immunology | Glomerulonephritis, Membranoproliferative - immunology | B-Lymphocytes - immunology | Lymphoma, B-Cell - pathology | Amyloid - immunology | Nephritis, Interstitial - etiology | Kidney Neoplasms - pathology | Aged | Kidney Diseases - etiology | Glomerulonephritis, Membranoproliferative - etiology | Nephritis, Interstitial - immunology | Nephrotic Syndrome - etiology | Cohort Studies | Index Medicus | Life Sciences | Immunology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1286 - 1297
The progression of kidney disease to renal failure correlates with infiltration of mononuclear immune cells into the tubulointerstitium. These infiltrates... 
MEDICINE, RESEARCH & EXPERIMENTAL | COMPARTMENT-SPECIFIC EXPRESSION | CRESCENTIC GLOMERULONEPHRITIS | MEDIATED-IMMUNITY | LUPUS NEPHRITIS | SENSITIZED CELLS | MURINE INTERSTITIAL NEPHRITIS | SUBSETS IN-VIVO | SELF-ANTIGENS | CD8(+) T-CELLS | CROSS-PRESENTATION | Kidney - pathology | Ovalbumin - immunology | Dendritic Cells - immunology | Kidney - immunology | Autoimmune Diseases - etiology | Muramidase - immunology | Cell Movement - immunology | Ovalbumin - metabolism | Lymphocyte Activation - immunology | T-Lymphocytes, Helper-Inducer - transplantation | T-Lymphocytes, Cytotoxic - transplantation | T-Lymphocytes, Helper-Inducer - immunology | Leukocytes, Mononuclear - immunology | Glomerulonephritis - etiology | Autoimmune Diseases - pathology | Kidney - physiopathology | Disease Models, Animal | Ovalbumin - genetics | T-Lymphocytes, Cytotoxic - immunology | Podocytes - metabolism | Mice, Inbred C57BL | Muramidase - genetics | Autoimmune Diseases - immunology | Glomerulonephritis - immunology | Mice, Transgenic | Muramidase - metabolism | Lymph Nodes - immunology | Antigen Presentation - immunology | Mice, Knockout | Animals | Glomerulonephritis - pathology | Leukocytes, Mononuclear - cytology | Dendritic Cells - cytology | Mice | Care and treatment | Usage | Dendritic cells | Development and progression | Models | Research | Kidney diseases | Macrophages | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2008, Volume 180, Issue 9, pp. 6270 - 6278
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 05/2013, Volume 24, Issue 6, pp. 906 - 916
Journal Article
European Journal of Immunology, ISSN 0014-2980, 02/2013, Volume 43, Issue 2, pp. 382 - 393
The autoimmune disease systemic lupus erythematosus is characterized by loss of tolerance to nuclear Ags and a heightened inflammatory environment, which... 
Lyn | autoantibody | IL‐21 | glomerulonephritis | IL‐6 | Glomerulonephritis | Autoantibody | IL-21 | IL-6 | SYSTEMIC-LUPUS-ERYTHEMATOSUS | TYROSINE KINASE | GERMINAL CENTER | IMMUNOLOGY | MYELOID CELLS | PLASMA-CELLS | HELPER T-CELLS | B-CELLS | BCL-6 EXPRESSION | AUTOIMMUNE-DISEASE | LYN-DEFICIENT MICE | Spleen - immunology | Antibodies, Antinuclear - immunology | Protein-Tyrosine Kinases - metabolism | Kidney - immunology | Lupus Erythematosus, Systemic - metabolism | Glomerulonephritis - metabolism | Interleukins - metabolism | Autoimmune Diseases - genetics | Interleukins - genetics | Kidney - metabolism | Protein-Tyrosine Kinases - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Myeloid Cells - immunology | Interleukins - immunology | Lupus Erythematosus, Systemic - immunology | src-Family Kinases - metabolism | Plasma Cells - metabolism | Autoimmune Diseases - metabolism | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | DNA - immunology | Interleukin-6 - genetics | Lymphocyte Activation | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Glomerulonephritis - genetics | Glomerulonephritis - immunology | Mice, Transgenic | Interleukin-6 - deficiency | src-Family Kinases - immunology | DNA - genetics | Autoantibodies - immunology | Animals | B-Lymphocytes - immunology | Spleen - metabolism | Lupus Erythematosus, Systemic - genetics | Interleukin-6 - immunology | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Mice | src-Family Kinases - genetics | Plasma Cells - immunology | Lupus | Autoimmunity | Autoantibodies | RNA | Analysis | Immunoglobulin G | DNA | Genetic research | T cells | Immunology | Autoimmune diseases | Deoxyribonucleic acid--DNA | Immune system | Index Medicus | autoimmunity
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 09/2012, Volume 7, Issue 9, pp. 1394 - 1400
Journal Article
Journal Article
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 05/2008, Volume 19, Issue 5, pp. 973 - 984
Anti-myeloperoxidase (anti-MPO) antibodies have been implicated in the pathogenesis of small-vessel vasculitis, but the molecular mechanisms by which these... 
GLOMERULONEPHRITIS | SYSTEMIC VASCULITIS | MYELOPEROXIDASE | FC-GAMMA RECEPTORS | ANTIMYELOPEROXIDASE ANTIBODIES | HOST-DEFENSE | P-SELECTIN | UROLOGY & NEPHROLOGY | ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES | ROLLING NEUTROPHILS | DEFICIENT MICE | Leukocyte Rolling - drug effects | Cell Communication - immunology | Vasculitis - metabolism | Interleukin-1beta - pharmacology | Microcirculation - metabolism | CD18 Antigens - immunology | Vasculitis - pathology | Male | Antibodies, Antineutrophil Cytoplasmic - immunology | Vasculitis - immunology | Leukocytes - immunology | Antibodies, Antineutrophil Cytoplasmic - metabolism | Receptors, IgG - genetics | Immunoglobulin G - immunology | Kidney Glomerulus - metabolism | Microcirculation - immunology | Renal Circulation - immunology | Antibodies, Monoclonal - immunology | Leukocytes - cytology | Peroxidase - immunology | Endothelial Cells - metabolism | Antibodies, Monoclonal - pharmacology | Hemorrhage - immunology | Mice, Inbred C57BL | Hemorrhage - metabolism | Kidney Glomerulus - pathology | Receptors, IgG - immunology | Leukocyte Rolling - immunology | Mice, Knockout | CD18 Antigens - metabolism | Endothelial Cells - immunology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Endothelial Cells - cytology | Cell Communication - drug effects | Mice | Kidney Glomerulus - immunology | Hemorrhage - pathology | Leukocytes - metabolism | Immunoglobulin G - metabolism | Peroxidase - metabolism | Index Medicus | Basic Research
Journal Article