X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2533) 2533
animals (2374) 2374
glucagon-like peptide-1 (2034) 2034
humans (1996) 1996
male (1486) 1486
biochemistry & molecular biology (1089) 1089
glucagon (1048) 1048
glucose (1021) 1021
mice (977) 977
glucagon-like peptide 1 (967) 967
rats (945) 945
insulin (920) 920
endocrinology & metabolism (875) 875
diabetes (870) 870
peptides (860) 860
glp-1 (754) 754
female (714) 714
type 2 diabetes (680) 680
pharmacology & pharmacy (642) 642
glucagon-like peptide 1 - metabolism (619) 619
insulin - metabolism (546) 546
diabetes mellitus, type 2 - drug therapy (519) 519
glucagon-like peptide-1 receptor (486) 486
secretion (485) 485
obesity (483) 483
physiology (449) 449
diabetes mellitus (428) 428
blood glucose - metabolism (423) 423
insulin secretion (414) 414
adult (404) 404
physiological aspects (397) 397
middle aged (392) 392
metabolism (386) 386
analysis (370) 370
expression (369) 369
amino acid sequence (366) 366
insulin - blood (362) 362
research (352) 352
dextrose (350) 350
proteins (350) 350
rodents (344) 344
insulin resistance (342) 342
glucagon-like peptide 1 - blood (336) 336
mice, inbred c57bl (329) 329
hypoglycemic agents - pharmacology (327) 327
digestive, oral, and skin physiology (325) 325
receptor (319) 319
cell biology (318) 318
cell line (318) 318
molecular sequence data (312) 312
hypoglycemic agents - therapeutic use (310) 310
endocrine system (308) 308
peptides - pharmacology (307) 307
hormones (290) 290
glucagon-like peptide 1 - pharmacology (288) 288
receptors, glucagon - metabolism (285) 285
exendin-4 (283) 283
diabetes mellitus, type 2 - metabolism (279) 279
food-intake (278) 278
signal transduction (278) 278
medicine (276) 276
pancreas (269) 269
rats, sprague-dawley (269) 269
multidisciplinary sciences (265) 265
insulin-secretion (261) 261
research article (258) 258
hormones, hormone substitutes, and hormone antagonists (257) 257
liraglutide (255) 255
glucagon - metabolism (252) 252
glucose - metabolism (251) 251
body weight (247) 247
glucose metabolism (247) 247
gastric-inhibitory polypeptide (243) 243
insulin-secreting cells - metabolism (238) 238
gene expression (237) 237
nutrition & dietetics (235) 235
peptide fragments - pharmacology (235) 235
rats, wistar (235) 235
exenatide (234) 234
health aspects (233) 233
glycemic control (231) 231
glucagon-like peptide 1 - analogs & derivatives (226) 226
glucose tolerance test (224) 224
peptides - chemistry (222) 222
activation (218) 218
incretin (218) 218
homeostasis (217) 217
glucagon-like peptides (216) 216
hyperglycemia (216) 216
aged (199) 199
islets of langerhans - metabolism (196) 196
peptide fragments - metabolism (196) 196
biophysics (195) 195
diet (195) 195
receptors (193) 193
glucagon-like peptide 1 - chemistry (192) 192
apoptosis (191) 191
biochemistry (190) 190
science (190) 190
in-vitro (189) 189
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3994) 3994
Japanese (32) 32
Chinese (6) 6
French (3) 3
German (2) 2
Romanian (1) 1
Russian (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2003, Volume 52, Issue 3, pp. 751 - 759
The rapid degradation of native glucagon-like peptide 1 (GLP-1) by dipeptidyl peptidase-IV (DPP-IV... 
GLP-1, glucagon-like peptide 1 | CHO, Chinese hamster ovary | GLP-1R, GLP-1 receptor | DAC, drug affinity complex | GIP, glucose-dependent insulinotropic peptide | AUC, area under the curve | HSA, human serum albumin | DPP-IV, dipeptidyl peptidase-IV | DIABETES-MELLITUS | DB/DB MICE | SERUM-ALBUMIN | IN-VIVO | ENDOCRINOLOGY & METABOLISM | DEPENDENT INSULINOTROPIC POLYPEPTIDE | BETA-CELL MASS | GASTRIC-INHIBITORY POLYPEPTIDE | IMPROVED GLUCOSE-TOLERANCE | FATTY ZUCKER RATS | ALBUMIN-BINDING | Diabetes Mellitus - blood | Dipeptidyl Peptidase 4 - metabolism | Glucagon-Like Peptide 1 | Hypoglycemic Agents - metabolism | Protein Precursors - chemistry | Humans | Maleimides - pharmacology | Body Weight - drug effects | RNA, Messenger - analysis | Glucagon - agonists | Peptides - metabolism | Transfection | Glucagon - chemistry | Maleimides - metabolism | Serum Albumin - chemistry | Cyclic AMP - metabolism | CHO Cells | Fibroblasts - metabolism | Protein Precursors - agonists | Receptors, Glucagon - genetics | Recombinant Proteins - metabolism | Cricetinae | Glucose Tolerance Test | Peptide Fragments - metabolism | Receptors, Glucagon - deficiency | Blood Glucose - analysis | Peptides - chemistry | Mice, Inbred C57BL | Diabetes Mellitus - drug therapy | Receptors, Glucagon - metabolism | Proinsulin - genetics | Hypoglycemic Agents - chemistry | Hypoglycemic Agents - pharmacology | Mice, Knockout | Peptides - pharmacology | Protein Precursors - metabolism | Peptide Fragments - chemistry | Animals | Glucagon-Like Peptide-1 Receptor | Peptide Fragments - agonists | Glucagon - metabolism | Mice | Maleimides - chemistry | Serum Albumin - metabolism | Type 2 diabetes | Physiological aspects | Care and treatment | Glucagon
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2014, Volume 136, Issue 37, pp. 12848 - 12851
... residues with conformationally constrained β-amino acid residues. This backbone-modification approach may be useful for developing stabilized analogues of other peptide... 
DESIGN | INHIBITION | GLUCAGON-LIKE PEPTIDE-1 | EXENDIN-4 | STABILITY | PROTEIN-PROTEIN INTERACTIONS | COUPLED RECEPTORS | AMINO-ACID RESIDUES | AGONISTS | CHEMISTRY, MULTIDISCIPLINARY | HELIX MIMICRY | Type 2 diabetes | Care and treatment | Peptides | Glucagon | Analysis | Residues | Surgical implants | Biomedical materials | In vivo testing | Surface chemistry | In vivo tests | Biocompatibility | Strategy | Communication
Journal Article
Lancet, The, ISSN 0140-6736, 2009, Volume 374, Issue 9683, pp. 39 - 47
... assigned to receive additional liraglutide 1·8 mg once a day (n=233) or exenatide 10 μg twice a day (n=231) in a 26-week open-label, parallel-group, multinational... 
Internal Medicine | METFORMIN | MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | SULFONYLUREA | GLUCAGON-LIKE PEPTIDE-1 | EXENDIN-4 | HUMAN GLP-1 ANALOG | BETA-CELL MASS | TREATED PATIENTS | ACUTE-PANCREATITIS | WEIGHT | Nausea - chemically induced | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Glycated Hemoglobin A - drug effects | Male | Diabetes Mellitus, Type 2 - metabolism | Weight Loss - drug effects | Dose-Response Relationship, Drug | Glucagon-Like Peptide 1 - agonists | Injections, Subcutaneous | Female | Hypoglycemia - chemically induced | Hypoglycemic Agents - therapeutic use | Drug Administration Schedule | Peptides - chemistry | Glucagon-Like Peptide 1 - analogs & derivatives | Venoms - adverse effects | Glucagon-Like Peptide 1 - chemistry | Linear Models | Logistic Models | Treatment Outcome | Hypoglycemic Agents - chemistry | Blood Glucose - drug effects | Analysis of Variance | Venoms - therapeutic use | Venoms - chemistry | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Glucagon-Like Peptide 1 - adverse effects | Hypoglycemic Agents - adverse effects | Liraglutide | Peptides - adverse effects | Peptides - therapeutic use | Glucagon-Like Peptide 1 - therapeutic use | Type 2 diabetes | Hypoglycemic agents | Dosage and administration | Drug therapy | Molecular structure | Clinical trials | Diabetes | Clinical medicine | Apoptosis | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2018, Volume 67, Issue 8, pp. 1538 - 1548
Glucagon-like peptide 1 receptor (GLP-1R) agonists are U.S. Food and Drug Administration-approved weight loss drugs... 
GLUCOSE-HOMEOSTASIS | ENERGY-EXPENDITURE | VISCERAL ILLNESS | FOOD-INTAKE | NUCLEUS | ENDOCRINOLOGY & METABOLISM | GLP-1 RECEPTORS | MICE | BRAIN ACTIVATION | AREA POSTREMA | AGONIST | Neurons - pathology | Vesicular Glutamate Transport Protein 2 - chemistry | Obesity - drug therapy | Diet, High-Fat - adverse effects | Glucagon-Like Peptide-1 Receptor - chemistry | Male | Green Fluorescent Proteins - genetics | Nerve Net - drug effects | Weight Loss - drug effects | Appetite Depressants - therapeutic use | Recombinant Fusion Proteins - metabolism | Glucagon-Like Peptide-1 Receptor - genetics | Glucagon-Like Peptide-1 Receptor - metabolism | Nerve Tissue Proteins - chemistry | Obesity - etiology | Neurons - metabolism | GABAergic Neurons - metabolism | Hypothalamus - drug effects | Green Fluorescent Proteins - chemistry | Neurons - drug effects | Vesicular Glutamate Transport Protein 2 - genetics | Hypoglycemic Agents - therapeutic use | Green Fluorescent Proteins - metabolism | Nerve Tissue Proteins - agonists | Vesicular Glutamate Transport Protein 2 - metabolism | GABAergic Neurons - drug effects | Mice, Transgenic | Energy Intake - drug effects | Hypothalamus - pathology | Random Allocation | Recombinant Fusion Proteins - chemistry | Nerve Tissue Proteins - genetics | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Nerve Tissue Proteins - metabolism | Animals | Hypothalamus - metabolism | Vesicular Inhibitory Amino Acid Transport Proteins - metabolism | Vesicular Inhibitory Amino Acid Transport Proteins - chemistry | Liraglutide - therapeutic use | Vesicular Inhibitory Amino Acid Transport Proteins - genetics | Nerve Net - metabolism | Genes, Reporter - drug effects | Glucagon-Like Peptide-1 Receptor - agonists | Appetite | Glucagon | Body weight | Dosage and administration | Research | Gene expression | Health aspects | Liraglutide | Index Medicus | Abridged Index Medicus | 0707 | Obesity Studies
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2007, Volume 104, Issue 3, pp. 937 - 942
Journal Article
The FASEB journal, ISSN 1530-6860, 2015, Volume 29, Issue 6, pp. 2397 - 2411
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 6, pp. 3642 - 3658
The glucagon-like peptide-1 receptor (GLP-1R) is a therapeutically important family B G protein-coupled receptor (GPCR) that is pleiotropically coupled to... 
PARATHYROID-HORMONE-RECEPTOR | CORTICOTROPIN-RELEASING-FACTOR | LIGAND-BINDING | CRITICAL DETERMINANTS | CRYSTAL-STRUCTURE | MOLECULAR RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINAL DOMAIN | DETERMINE SPECIFICITY | PROTEIN-COUPLED-RECEPTOR | MUSCARINIC ACETYLCHOLINE-RECEPTORS | MAP Kinase Signaling System - physiology | Receptors, Glucagon - antagonists & inhibitors | Cricetulus | Humans | Mutation, Missense | Glucagon-Like Peptide 1 - genetics | Mitogen-Activated Protein Kinase 1 - chemistry | Cyclic AMP - chemistry | Mitogen-Activated Protein Kinase 1 - genetics | Cyclic AMP - genetics | Mitogen-Activated Protein Kinase 3 - chemistry | Cyclic AMP - metabolism | CHO Cells | Protein Structure, Tertiary | Receptors, Glucagon - agonists | Receptors, Glucagon - genetics | Cricetinae | Glucagon-Like Peptide 1 - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Peptides - chemistry | Protein Structure, Secondary | Glucagon-Like Peptide 1 - pharmacology | Receptors, Glucagon - metabolism | Glucagon-Like Peptide 1 - chemistry | Peptides - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Glucagon-Like Peptide-1 Receptor | Mitogen-Activated Protein Kinase 3 - metabolism | Receptors, Glucagon - chemistry | Protein Binding | Amino Acid Substitution | Mitogen-Activated Protein Kinase 1 - metabolism | G Protein-coupled Receptors (GPCR) | Peptide Hormones | Receptor Structure-Function | Signal Transduction | Cell Signaling | Ligand-directed Signal Bias | Glucagon-like Peptide-1 Receptor
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article