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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 09/2012, Volume 56, Issue 9, pp. 4793 - 4799
Journal Article
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 08/2019, Volume 370, Issue 2, pp. 327 - 336
Methylprednisolone (MPL), a corticosteroid of intermediate potency, remains an important immunomodulatory agent for autoimmune diseases. Although sex... 
DRUG | CYTOCHROME-P450 | DEXAMETHASONE | GLUCOCORTICOIDS | METABOLISM | RATS | GENDER | PHARMACOLOGY & PHARMACY | PREDNISOLONE | EXPRESSION | DISPOSITION | Index Medicus
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 05/2017, Volume 57, Issue 5, pp. 627 - 639
In Duchenne muscular dystrophy (DMD), NF‐κB is activated in skeletal muscle from infancy regardless of the underlying dystrophin mutation and drives... 
pharmacokinetics | NF‐κB | edasalonexent | inflammation | Duchenne muscular dystrophy | CAT‐1004 | NF-κB | CAT-1004 | CELLS | ACTIVATION | GLUCOCORTICOIDS | OMEGA-3-FATTY-ACIDS | INFLAMMATORY MYOPATHIES | SALICYLATES | DEGENERATION | SKELETAL-MUSCLE | NF-kappa B | PHARMACOLOGY & PHARMACY | EICOSAPENTAENOIC ACID | EXPRESSION | Leukocytes, Mononuclear - metabolism | Leukocytes, Mononuclear - drug effects | Gene Expression - drug effects | Salicylamides - blood | Humans | Middle Aged | Male | NF-kappa B - metabolism | Arachidonic Acids - pharmacology | Young Adult | Arachidonic Acids - pharmacokinetics | Signal Transduction - drug effects | Arachidonic Acids - blood | Arachidonic Acids - adverse effects | Adult | Female | Muscular Dystrophy, Duchenne - blood | Salicylamides - adverse effects | Proteome - metabolism | Salicylamides - pharmacokinetics | Salicylamides - pharmacology | Headache | Animal models | Medical services | Leukocytes (mononuclear) | Docosahexaenoic acid | Muscular dystrophy | Duchenne's muscular dystrophy | Cleavage | Degeneration | Inhibition | Safety | Dystrophin | Salicylic acid | Pharmacodynamics | Medical treatment | Oral administration | Muscles | Diarrhea | Pharmacology | Gene expression | Disease control | Skeletal muscle | Regeneration | Acids | Dystrophy | Mutation | Intracellular | Pharmacokinetics | Index Medicus
Journal Article
Journal Article
Epilepsia, ISSN 0013-9580, 01/2013, Volume 54, Issue 1, pp. 11 - 27
Several commonly prescribed antiepileptic drugs (AEDs)—including phenobarbital, phenytoin, and carbamazepine—stimulate the synthesis of a broad range of... 
Enzyme‐inducing antiepileptic drug | Vascular disease | Drug metabolism | Pharmacokinetic interactions | Osteoporosis | Sexual dysfunction | Enzyme-inducing antiepileptic drug | DOSE-DEPENDENT INDUCTION | VASCULAR RISK-FACTORS | VITAMIN-D METABOLISM | NEWLY-DIAGNOSED EPILEPSY | QUALITY STANDARDS SUBCOMMITTEE | PREGNANE-X-RECEPTOR | CLINICAL NEUROLOGY | PATIENTS RECEIVING CARBAMAZEPINE | RECURRENT MALIGNANT GLIOMA | BRAIN-TUMOR CONSORTIUM | INCREASED BONE TURNOVER | Anticonvulsants - pharmacokinetics | Anti-Retroviral Agents - pharmacokinetics | Humans | Immunosuppressive Agents - pharmacokinetics | Anticonvulsants - therapeutic use | Male | Vascular Diseases - chemically induced | Pregnancy | Cytochromes - biosynthesis | Anticonvulsants - adverse effects | Drug Interactions | Enzyme Induction - drug effects | Epilepsy - drug therapy | Female | Antineoplastic Agents - pharmacokinetics | Contraceptives, Oral, Hormonal - pharmacokinetics | Antidepressive Agents - pharmacokinetics | Drugs | Antiviral agents | Enzymes | Corticosteroids | Comorbidity | Epilepsy | Anticoagulants (Medicine) | Blood circulation disorders | Phenobarbital | Physiological aspects | Hormones, Sex | Oral contraceptives | Sexual disorders | Statins | Phenytoin | Anticoagulants | Glucocorticoids | Antihypertensives | Toxicity | Withdrawal | Mortality | Antiepileptic agents | Immunosuppressive agents | Graft rejection | Sex hormones | Vascular diseases | Acquired immune deficiency syndrome | Analgesics | statins | Metabolic pathways | Cancer | Index Medicus
Journal Article
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 10/2016, Volume 11, Issue 10, pp. 1777 - 1782
Journal Article
HIV Medicine, ISSN 1464-2662, 10/2013, Volume 14, Issue 9, pp. 519 - 529
As a consequence of inhibition of the hepatic cytochrome P450 3A4 isozyme, treatment with HIV protease inhibitors can result in significant drug−drug... 
corticosteroid | pharmacokinetics | protease inhibitors | drug interactions | HIV | ritonavir | Corticosteroid | Protease inhibitors | Pharmacokinetics | Ritonavir | Drug interactions | NASAL FLUTICASONE | INFECTIOUS DISEASES | BECLOMETHASONE DIPROPIONATE | BINDING-KINETICS | INFECTED PATIENT | ABSOLUTE BIOAVAILABILITY | HUMAN GLUCOCORTICOID-RECEPTOR | OF-THE-LITERATURE | SECONDARY ADRENAL INSUFFICIENCY | RITONAVIR-FLUTICASONE INTERACTION | IATROGENIC CUSHINGS-SYNDROME | Fluocinolone Acetonide - administration & dosage | Beclomethasone - pharmacokinetics | Humans | Middle Aged | Child, Preschool | HIV Seropositivity - drug therapy | Infant | Male | Fluocinolone Acetonide - adverse effects | Young Adult | Drug Interactions | Ritonavir - adverse effects | Cushing Syndrome - chemically induced | Adult | Anti-Inflammatory Agents - pharmacokinetics | Female | Child | Cushing Syndrome - drug therapy | HIV Protease Inhibitors - adverse effects | Beclomethasone - administration & dosage | Fluocinolone Acetonide - analogs & derivatives | Ritonavir - administration & dosage | Administration, Inhalation | HIV Protease Inhibitors - administration & dosage | Administration, Intranasal | HIV Protease Inhibitors - therapeutic use | Adrenal Cortex Hormones - adverse effects | Ritonavir - pharmacokinetics | Adolescent | Beclomethasone - adverse effects | Fluocinolone Acetonide - pharmacokinetics | Aged | Adrenal Cortex Hormones - pharmacokinetics | Adrenal Cortex Hormones - administration & dosage | Antiviral agents | Corticosteroids | Proteases | Antiasthmatic agents | HIV patients | HIV (Viruses) | Anti-HIV agents
Journal Article
Pulmonary Pharmacology & Therapeutics, ISSN 1094-5539, 10/2019, Volume 58, p. 101828
The differences in the pharmacokinetic (PK) characteristics of inhaled corticosteroids (ICSs) critically influence the profile of each of them, but also the... 
Therapeutic index | Pharmacodynamics | Inhaled corticosteroids | Glucocorticoid receptors | Pharmacokinetics | Asthma
Journal Article