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Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 03/2012, Volume 55, Issue 3, pp. 790 - 799
It is well established that inactivation of the central endocannabinoid system (ECS) through antagonism of cannabinoid receptor 1 (CB1R) reduces food intake... 
RISK-FACTORS | COENZYME-A REDUCTASE | CONJUGATED LINOLEIC-ACID | FOOD-INTAKE | OVERWEIGHT PATIENTS | WEIGHT-LOSS | GASTROENTEROLOGY & HEPATOLOGY | TRANSCRIPTIONAL REGULATION | GLUCOKINASE GENE | INDUCED OBESE MICE | CB1 RECEPTORS | Protein Kinases - metabolism | Carbohydrate Metabolism - drug effects | Male | RNA, Messenger - metabolism | Piperidines - pharmacology | Mice, Mutant Strains | Dyslipidemias - prevention & control | Dyslipidemias - etiology | Disease Models, Animal | Pyrazoles - pharmacology | Fatty Liver - metabolism | Obesity - complications | Tissue Culture Techniques | Liver - metabolism | Mice, Inbred C57BL | Fatty Liver - prevention & control | Obesity - physiopathology | Cholesterol - metabolism | Obesity - metabolism | Gene Expression Regulation - drug effects | Animals | Receptor, Cannabinoid, CB1 - genetics | Oxygen Consumption - drug effects | Lipid Metabolism - drug effects | Receptor, Cannabinoid, CB1 - drug effects | Dyslipidemias - metabolism | Mice | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Lipid Metabolism - physiology | Fatty Liver - etiology | Index Medicus | Obesity | Dyslipidemias | Pyrazoles | Liver | Carbohydrate Metabolism | Gene Expression Regulation | Oxygen Consumption | Lipid Metabolism | Cholesterol | Fatty Liver | Life Sciences | Protein Kinases | Piperidines | Receptor, Cannabinoid, CB1 | Food and Nutrition | RNA, Messenger
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2000, Volume 275, Issue 46, pp. 36269 - 36277
Increases in glucose concentration control the transcription of the preproinsulin (PPI) gene and several other genes in the pancreatic islet beta -cell.... 
RESPONSE ELEMENT | CA2+ CONCENTRATION | UPSTREAM STIMULATORY FACTOR | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PYRUVATE-KINASE GENE | METABOLIC-REGULATION | ACETYL-COA CARBOXYLASE | TRANSCRIPTIONAL REGULATION | CARBOHYDRATE REGULATION | TRANSPORTER ISOFORMS | Islets of Langerhans - drug effects | Luciferases - metabolism | Proinsulin - metabolism | Multienzyme Complexes - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Promoter Regions, Genetic - genetics | AMP-Activated Protein Kinases | Luciferases - genetics | Transfection | Islets of Langerhans - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Adenoviridae - genetics | Chromones - pharmacology | Insulin - genetics | Insulin Secretion | Genes, Reporter | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Insulin - pharmacology | Protein Precursors - genetics | Microinjections | Islets of Langerhans - enzymology | Morpholines - pharmacology | Glucokinase - genetics | Proinsulin - genetics | Glucose - pharmacology | Enzyme Activation - drug effects | Multienzyme Complexes - antagonists & inhibitors | Protein Precursors - metabolism | Gene Expression Regulation - drug effects | Phosphatidylinositol 3-Kinases - genetics | Insulin - metabolism | Animals | Plasmids | Glucose - metabolism | Models, Genetic | Pyruvate Kinase - genetics | tolbutamide | L-PK gene | Index Medicus
Journal Article
Metabolism, ISSN 0026-0495, 2011, Volume 60, Issue 4, pp. 579 - 585
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, pp. e0159077 - e0159077
Dehydroepiandrosterone ( DHEA) has a fat-reducing effect, while little information is available on whether DHEA regulates glucose metabolism, which would in... 
DHEA | ANTIOBESITY | OBESITY | LIPID-METABOLISM PARAMETERS | MULTIDISCIPLINARY SCIENCES | GLUCONEOGENIC ENZYMES | ENDOCRINE FUNCTIONS | BETA-CELLS | IN-VIVO | GENE-EXPRESSION | ADIPOSE-TISSUE | Glucose Transport Proteins, Facilitative - metabolism | Gluconeogenesis - drug effects | Body Weight - drug effects | Dehydroepiandrosterone - administration & dosage | Diet, High-Fat - adverse effects | Phosphatidylinositol 3-Kinases - metabolism | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-akt - genetics | Glycogen - metabolism | Liver - drug effects | Time Factors | Proto-Oncogene Proteins c-akt - metabolism | Body Mass Index | Dehydroepiandrosterone - pharmacology | Liver - metabolism | RNA, Messenger - genetics | Rats | Rats, Sprague-Dawley | Phosphatidylinositol 3-Kinases - genetics | Animals | Phosphofructokinase-2 - metabolism | Hormones - metabolism | Signal Transduction - drug effects | Receptor, Insulin - metabolism | Blood Glucose - metabolism | Obesity | Metabolic diseases | Dehydroepiandrosterone | Usage | Health aspects | Risk factors | Veterinary colleges | Succinate dehydrogenase | Glycogen synthase | Body weight | Liver | Pyruvic acid | AKT protein | Activation | mRNA | Glucose | Kinases | Dehydrogenase | High fat diet | Glucose metabolism | Signal transduction | Rodents | Phosphofructokinase | Glucose transporter | Pyruvate kinase | Glycogen | Dietary supplements | Muscles | Malate dehydrogenase | Metabolism | Insulin | Body weight gain | Substrates | Phosphorylase | 1-Phosphatidylinositol 3-kinase | Signaling | Malate | Diet | Leptin | Glycogen phosphorylase | Glucokinase | Catabolism | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, pp. 35908 - 35908
Human induced pluripotent stem cells (hiPSCs) provide a potential resource for regenerative medicine. To identify the signalling pathway(s) contributing to the... 
PLURIPOTENT-STEM-CELLS | DERIVATION | IN-VITRO | DEPENDENT ADENOVIRAL VECTORS | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | INSULIN-PRODUCING CELLS | ENDODERM | SECRETION | EXPRESSION | EFFICIENT | Islets of Langerhans - drug effects | Humans | Basic Helix-Loop-Helix Transcription Factors - metabolism | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Induced Pluripotent Stem Cells - cytology | Insulin - genetics | Insulin Secretion | Induced Pluripotent Stem Cells - metabolism | Cell Line | Gene Targeting | Promoter Regions, Genetic | Basic Helix-Loop-Helix Transcription Factors - genetics | Induced Pluripotent Stem Cells - drug effects | Signal Transduction | Bacterial Proteins - genetics | Nerve Tissue Proteins - genetics | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Gene Knock-In Techniques | Nerve Tissue Proteins - metabolism | Cell Lineage | Insulin - metabolism | Cell Differentiation - drug effects | Models, Biological | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Luminescent Proteins - metabolism | Nkx6.1 protein | Fibroblast growth factor | Secretion | High-throughput screening | Insulin | Promoters | Neurogenin 3 | Neurogenin | Regeneration | Signal transduction | Glucokinase | Stem cells | Fibroblasts | Pancreas | Growth factors | Fibroblast growth factor receptor 1 | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus
Journal Article