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SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 9
Previous studies have shown that an intronic variant rs780094 of the GCKR gene (glucokinase regulatory protein) is significantly associated with several... 
HYPERGLYCEMIA | METABOLISM | COMMON VARIANT | ACIDS | FATTY LIVER-DISEASE | MULTIDISCIPLINARY SCIENCES | RISK | SECRETION | GLUCOKINASE | INSULIN SENSITIVITY | GLUCOSE-TOLERANCE | Metabolomics | Statistical analysis | Threonine | Serine | Tryptophan | Mass spectroscopy | Lipids | Population studies | Sphingolipids | Genetic variance | Vitamin A | Pleiotropy | Metabolites | Glucokinase | Alleles | Lipid metabolism | Sulfate
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 1803
Nearly two-thirds of U.S. adults are overweight or obese, putting them at risk for other serious medical conditions, including diabetes and heart disease. The... 
Phenotypes | Amygdala | Neurons | Diabetes mellitus | Body weight | Chemoreception | Glucose | Metabolism | Coronary artery disease | Feeding | Glucose metabolism | Social interactions | Social behavior | Glucokinase | Adrenergic receptors | Anxiety | Diabetes | Pancreas | Propranolol | Heart diseases | Tracers
Journal Article
Frontiers in Endocrinology, ISSN 1664-2392, 2019, Volume 10, pp. 254 - 254
In mammals, glucosensing markers reside in brain areas known to play an important role in the control of food intake. The best characterized glucosensing... 
POMC | Brain | Neuron | Fish | AGRP | Glucosensing | Glucokinase (GK) | glucokinase (GK) | ANTAGONIST | 4 RECEPTOR | glucosensing | FOOD-INTAKE | neuron | brain | GLUCOKINASE | AGOUTI-RELATED PROTEIN | COEXPRESSION | ENERGY HOMEOSTASIS | fish | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | HYPOTHALAMUS | Neuropeptides | Glucose | Trout | Isoenzymes | Dextrose
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 446 - 14
Hepatocellular carcinoma (HCC) cells are metabolically distinct from normal hepatocytes by expressing the high-affinity hexokinase (HK2) and suppressing... 
C-13-METABOLIC FLUX ANALYSIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | GROWTH | PARALLEL LABELING EXPERIMENTS | MASS ISOTOPOMER DISTRIBUTIONS | REDD1 | EXPRESSION | CANCER-THERAPY | MTOR | DELETION | Niacinamide - analogs & derivatives | Metformin - therapeutic use | Humans | Male | Antineoplastic Agents - therapeutic use | Metabolic Flux Analysis | Molecular Targeted Therapy | Carcinogenesis | Carcinoma, Hepatocellular - drug therapy | Antineoplastic Agents - pharmacology | Liver Neoplasms - enzymology | Hypoglycemic Agents - therapeutic use | Hexokinase - antagonists & inhibitors | Metformin - pharmacology | Liver Neoplasms - drug therapy | Oxidative Phosphorylation | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Mechanistic Target of Rapamycin Complex 1 - antagonists & inhibitors | Carcinoma, Hepatocellular - enzymology | Mechanistic Target of Rapamycin Complex 1 - metabolism | Hep G2 Cells | Hypoglycemic Agents - pharmacology | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Sorafenib | Glycolysis | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Hexokinase - metabolism | Phosphorylation | Secretion | Serine | Pyruvic acid | Hepatocellular carcinoma | Fluxes | Glycine | Hexokinase | Liver cancer | Mitochondria | Depletion | Clonal deletion | Oxidative phosphorylation | Hepatocytes | Cell death | Rodents | Glucokinase | Deletion | Tumorigenesis | Lactic acid | Metformin | Inhibition | Apoptosis | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 546 - 9
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 1986 - 10
Journal Article
Cytokine and Growth Factor Reviews, ISSN 1359-6101, 12/2018, Volume 44, pp. 18 - 27
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 11/2018, Volume 123, Issue 5, pp. 539 - 548
Obesity and insulin resistance are associated with overexpression of retinaldehyde dehydrogenase 1 ( RALDH 1). We aimed to investigate the roles of hepatic... 
PHOSPHOENOLPYRUVATE CARBOXYKINASE | IN-VITRO | OBESITY | LIPID-METABOLISM | INSULIN-RESISTANCE | ISOTRETINOIN | RATS | 13-CIS-RETINOIC ACID | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TRANS-RETINOIC ACID | ALL-TRANS | Humans | Retinal Dehydrogenase - metabolism | Glucose Tolerance Test - methods | Phosphoenolpyruvate Carboxykinase (GTP) - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Insulin - blood | Monoterpenes - pharmacology | Isoenzymes - metabolism | Diabetes Mellitus, Experimental - metabolism | Diet, High-Fat - methods | Hepatocytes - drug effects | Hyperlipidemias - metabolism | Mice, Inbred C57BL | Insulin Resistance | Rats | Glucokinase - metabolism | Hep G2 Cells | Animals | Diabetes Mellitus, Experimental - etiology | Hyperlipidemias - etiology | Lipid Metabolism - drug effects | Glucose - metabolism | Retinal Dehydrogenase - antagonists & inhibitors | Mice | Isoenzymes - antagonists & inhibitors | Isoenzymes | Physiological aspects | Insulin resistance | Glucose | Glucose tolerance tests | Insulin | Dextrose | Dehydrogenases | Fat metabolism | Liver | Impairment | Pyruvic acid | Lipids | Dehydrogenase | High fat diet | Glucose metabolism | Rodents | Hyperlipidemia | Diabetes mellitus | Retinaldehyde | Metabolism | Glucose tolerance | Hepatocytes | Diet | Glucokinase | Retinaldehyde dehydrogenase | Diabetes | Citral | Index Medicus
Journal Article
Journal Article