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Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5927, pp. 651 - 654
The circadian clock is encoded by a transcription-translation feedback loop that synchronizes behavior and metabolism with the light-dark cycle. Here we report... 
RNA | Hepatocytes | Liver | Genes | Oscillation | Control loops | Reports | Biosynthesis | Gene expression regulation | Metabolism | Research universities | LIFE-SPAN | CELLS | GLUCOSE-HOMEOSTASIS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | EXTENSION | COMPONENT | SIRT1 | BINDING | CALORIE RESTRICTION | Humans | Adipose Tissue, White - metabolism | Hepatocytes - metabolism | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | Sirtuin 1 | NAD - biosynthesis | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Transcription, Genetic | Biological Clocks | Nuclear Proteins - genetics | Acrylamides - pharmacology | Cytokines - genetics | ARNTL Transcription Factors | Cell Line | Basic Helix-Loop-Helix Transcription Factors - genetics | Cytokines - metabolism | Liver - metabolism | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Transcription Factors - genetics | Circadian Rhythm | Period Circadian Proteins | Feedback, Physiological | Nicotinamide Phosphoribosyltransferase - genetics | Animals | CLOCK Proteins | Cell Line, Tumor | Protein Binding | Trans-Activators - metabolism | Mice | Cytokines - antagonists & inhibitors | Sirtuins - metabolism | Enzymes | Circadian rhythm | Cellular biology | Animal behavior | Rodents | Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 05/2018, Volume 360, Issue 6389, p. eaan5780
NAD(+) (nicotinamide adenine dinucleotide in its oxidized state) is an essential molecule for a variety of physiological processes. It is synthesized in... 
CELLS | POLY(ADP-RIBOSE) | NUCLEAR | ENZYMES | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | DIFFERENTIATION | ADIPOGENESIS | HISTONE ACETYLATION | PARP-1 | BINDING | NIH 3T3 Cells | NAD - genetics | CCAAT-Enhancer-Binding Protein-beta | Nicotinamide-Nucleotide Adenylyltransferase - metabolism | Humans | Substrate Specificity | Adipocytes - cytology | Cytoplasm - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | Animals | Cell Nucleus - metabolism | Adipocytes - metabolism | NAD - biosynthesis | Cell Line, Tumor | Glucose - metabolism | Transcription, Genetic | Mice | Adipogenesis - genetics | Competition | Cell culture | Regulations | Transcription factors | Differentiation (biology) | Adipocytes | Glucose | ADP | Nuclei | Signal transduction | Mitochondria | Enzymatic activity | Restoration | Physiology | Inhibition | Catalysis | Chemical synthesis | Enzymes | Adenosine diphosphate | Preadipocytes | Metabolism | Gene expression | Substrates | Molecular chains | Golgi apparatus | Poly(ADP-ribose) Polymerase 1 | Nicotinamide adenine dinucleotide | Metabolic pathways | Nuclei (cytology) | Nicotinamide | NADPH | Fat metabolism | Gene regulation | Biosynthesis | Catalytic activity | Mammalian cells | Glucose metabolism | Reduction | Adipogenesis | ADP-ribosylation | Deprivation | Adenosine | Poly(ADP-ribose) polymerase | Adenine | NAD | Depletion | Glycolysis | Catabolism | Cytoplasm | Index Medicus
Journal Article
The Plant Journal, ISSN 0960-7412, 03/2016, Volume 85, Issue 6, pp. 730 - 742
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 20, Issue 3, pp. 315 - 327
Inactivation of the TCA cycle enzyme, fumarate hydratase ( ), drives a metabolic shift to aerobic glycolysis in -deficient kidney tumors and cell lines from... 
CELLS | SUCCINATE-DEHYDROGENASE | COMPLEX-II | ONCOLOGY | GLUCOSE-METABOLISM | GROWTH | HEREDITARY LEIOMYOMATOSIS | RENAL-CANCER | CARCINOMA | HYPOXIA-INDUCIBLE FACTOR-1 | REGULATORY PROTEINS | CELL BIOLOGY | AMP-Activated Protein Kinases - metabolism | Tumor Suppressor Protein p53 - biosynthesis | Cation Transport Proteins - biosynthesis | Humans | Leiomyomatosis - metabolism | Fumarate Hydratase - deficiency | Kidney Neoplasms - metabolism | Glycolysis - drug effects | Iron Regulatory Protein 2 - biosynthesis | Neoplastic Syndromes, Hereditary | Fumarate Hydratase - metabolism | Ribose - biosynthesis | Acetyl Coenzyme A - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Iron - deficiency | Leiomyomatosis - pathology | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Leiomyomatosis - congenital | Ribosomal Protein S6 - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | NADP - biosynthesis | Uterine Neoplasms | Animals | Iron Regulatory Protein 1 - metabolism | Thenoyltrifluoroacetone - pharmacology | Ribosomal Protein S6 - metabolism | Kidney Neoplasms - enzymology | Skin Neoplasms | Acetyl-CoA Carboxylase - biosynthesis | Cell Line, Tumor | Kidney Neoplasms - pathology | Mice | Iron Regulatory Protein 1 - biosynthesis | Acetyl-CoA Carboxylase - metabolism | Iron Regulatory Protein 2 - metabolism | Enzymes | Glucose metabolism | Research | Tumor proteins | Oncology, Experimental | Cancer | Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 2/2007, Volume 50, Issue 2, pp. 348 - 358
Journal Article