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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2016, Volume 126, Issue 11, pp. 4372 - 4386
Obese, insulin-resistant states are characterized by a paradoxical pathogenic condition in which the liver appears to be selectively insulin resistant.... 
RAT-LIVER | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | DE-NOVO LIPOGENESIS | TRANSCRIPTION FACTOR FOXO1 | FATTY LIVER-DISEASE | OB/OB MICE | ELEMENT-BINDING PROTEIN | HEPATIC STEATOSIS | ADIPOSE-TISSUE | PLASMA TRIGLYCERIDES | Glucose Intolerance - metabolism | Glucose-6-Phosphatase - genetics | Fatty Liver - pathology | Humans | Male | Glucose - biosynthesis | Glucose Intolerance - pathology | Fatty Liver - chemically induced | Glycolysis - drug effects | Glycolysis - genetics | Lipogenesis - genetics | Female | Glucose Intolerance - chemically induced | Insulin - genetics | Nuclear Proteins - genetics | Fatty Liver - genetics | Forkhead Box Protein O1 - metabolism | Glucose Intolerance - genetics | Fatty Liver - metabolism | Fructose - toxicity | Insulin Resistance | Glucose - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | Glucose-6-Phosphatase - metabolism | Mice, Knockout | Transcription Factors - metabolism | Insulin - metabolism | Animals | Signal Transduction - drug effects | Lipogenesis - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Forkhead Box Protein O1 - genetics | Obesity | Analysis | Insulin resistance | Genetic aspects | Genetic transcription | Research | Risk factors | Protein binding | Glucose | Metabolites | Rodents | Liver | Index Medicus | Abridged Index Medicus
Journal Article
Developmental Cell, ISSN 1534-5807, 2002, Volume 3, Issue 1, pp. 25 - 38
Insulin signaling in adipose tissue plays an important role in lipid storage and regulation of glucose homeostasis. Using the Cre-loxP system, we created mice... 
DIABETES-MELLITUS | TARGETED DISRUPTION | METABOLISM | CULTURED RAT ADIPOCYTES | OB GENE-EXPRESSION | RESISTANCE | MUSCLE | CELL-SIZE | DEVELOPMENTAL BIOLOGY | PLASMA LEPTIN | LEPTIN SECRETION | CELL BIOLOGY | Glucose Intolerance - metabolism | Ventromedial Hypothalamic Nucleus - drug effects | Ventromedial Hypothalamic Nucleus - physiopathology | Diabetes Mellitus, Type 2 - genetics | Adipose Tissue - physiopathology | Receptor, Insulin - deficiency | Male | Ventromedial Hypothalamic Nucleus - pathology | Diabetes Mellitus, Type 2 - metabolism | Body Weight - genetics | Obesity - genetics | Adiponectin | DNA-Binding Proteins - metabolism | Adipose Tissue - metabolism | Muscle Proteins | Cell Size - genetics | Leptin - blood | Receptor, Insulin - genetics | Female | CCAAT-Enhancer-Binding Proteins - genetics | Energy Metabolism - genetics | Monosaccharide Transport Proteins - metabolism | Glucose Intolerance - physiopathology | Monosaccharide Transport Proteins - genetics | CCAAT-Enhancer-Binding Proteins - metabolism | Glucose Intolerance - genetics | Glucose Transporter Type 4 | Intercellular Signaling Peptides and Proteins | Glucose Transporter Type 1 | Obesity - physiopathology | DNA-Binding Proteins - genetics | Mice, Knockout | Obesity - metabolism | Proteins - genetics | Insulin - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Proteins - metabolism | Adipocytes - metabolism | Glucose - metabolism | Mice | Transcription Factors | Aurothioglucose - pharmacology | Sterol Regulatory Element Binding Protein 1 | Index Medicus
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 11/2010, Volume 51, Issue 11, pp. 3306 - 3315
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2014, Volume 289, Issue 25, pp. 17338 - 17349
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 06/2012, Volume 302, Issue 11, pp. 1373 - 1380
Journal Article
Endocrinology, ISSN 0013-7227, 02/2012, Volume 153, Issue 2, pp. 672 - 682
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 130, Issue 3, pp. 456 - 469
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 725 - 738
Mammalian target of rapamycin complex 2 (mTORC2) phosphorylates and activates AGC kinase family members, including Akt, SGK1, and PKC, in response to... 
TRANSCRIPTION FACTORS | LIPID-METABOLISM | INSULIN-RESISTANCE | ELEMENT-BINDING PROTEIN-1C | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | MOTIF PHOSPHORYLATION | DIABETIC-NEPHROPATHY | GLUCOSE-UTILIZATION | CELL-GROWTH | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | Glucose Intolerance - metabolism | Phosphorylation | Liver - enzymology | TOR Serine-Threonine Kinases - metabolism | Homeostasis | Glycogen Synthase Kinase 3 beta | Male | Hepatocytes - metabolism | Mechanistic Target of Rapamycin Complex 2 | Hyperglycemia - genetics | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - metabolism | Forkhead Transcription Factors - metabolism | Trans-Activators - genetics | Hyperinsulinism - genetics | Insulin - genetics | Lipogenesis | Proto-Oncogene Proteins c-akt - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Gluconeogenesis | Hyperinsulinism - metabolism | Glucose Intolerance - genetics | Signal Transduction | Liver - metabolism | Glucokinase - genetics | Glucose - genetics | Lipid Metabolism | Forkhead Transcription Factors - genetics | Glucokinase - metabolism | Glycogen Synthase Kinase 3 - metabolism | Mice, Knockout | Hyperglycemia - metabolism | Proteins - genetics | Insulin - metabolism | Animals | Proteins - metabolism | Trans-Activators - deficiency | Glycogen Synthase Kinase 3 - genetics | Sterol Regulatory Element Binding Protein 1 - genetics | Glucose - metabolism | Glycolysis | Trans-Activators - metabolism | Forkhead Box Protein O1 | Mice | Transcription Factors | Glucose metabolism | Hyperglycemia | Glucose | Isoenzymes | Dextrose | Index Medicus
Journal Article