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Journal Article
Cell metabolism, ISSN 1550-4131, 2014, Volume 20, Issue 1, pp. 61 - 72
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 12/2007, Volume 213, Issue 3, pp. 834 - 843
Sugar consumption and subsequent sugar metabolism are known to regulate the expression of genes involved in intestinal sugar absorption and delivery... 
FRUCTOSE TRANSPORTER GLUT5 | PHYSIOLOGY | MESSENGER-RNA | MAMMALIAN SWEET | SMALL-INTESTINE | GLUCOSE SENSOR | ELEMENT-BINDING PROTEIN | SUCRASE-ISOMALTASE | TASTE RECEPTORS | UP-REGULATION | GENE-TRANSCRIPTION | CELL BIOLOGY | Cell Polarity | Glucose Transporter Type 2 - genetics | Glucose Transporter Type 5 - metabolism | Enterocytes - metabolism | Sweetening Agents - metabolism | Humans | RNA, Messenger - metabolism | Fructose - metabolism | Glucose Transporter Type 2 - metabolism | Sodium-Glucose Transporter 1 - genetics | Transfection | Cloning, Molecular | Sucrose - metabolism | Jejunum - cytology | Sodium-Glucose Transporter 1 - metabolism | Monosaccharide Transport Proteins - metabolism | Monosaccharide Transport Proteins - genetics | Oligo-1,6-Glucosidase - genetics | Caco-2 Cells | Protein Structure, Tertiary | Green Fluorescent Proteins - metabolism | Promoter Regions, Genetic | Mice, Inbred C57BL | Hexoses - metabolism | Mice, Knockout | Animals | Glucose Transporter Type 2 - chemistry | Sucrase - genetics | Glucose - metabolism | Mice | Glucose Transporter Type 5 - genetics | Green Fluorescent Proteins | Sucrose | Glucose | Cellular Biology | Tissues and Organs | Life Sciences | Jejunum | Oligo-1,6-Glucosidase | Sucrase | Food and Nutrition | Hexoses | Glucose Transporter Type 5 | Glucose Transporter Type 2 | Biochemistry, Molecular Biology | Sodium-Glucose Transporter 1 | Fructose | Human health and pathology | Enterocytes | Monosaccharide Transport Proteins | RNA, Messenger | Sweetening Agents
Journal Article
Neuroscience, ISSN 0306-4522, 2008, Volume 155, Issue 2, pp. 423 - 438
Abstract Nutrient transporters and ABC efflux pumps at the blood–brain barrier are major determinants of drug penetration into the brain... 
Neurology | abluminal | cerebral microvessels | luminal | ABC transporter | choroid plexus | NEUROSCIENCES | P-GLYCOPROTEIN ABCB1 | MICROVESSEL ENDOTHELIUM | AMINO-ACID TRANSPORTER | LUMINAL SIDE | ABLUMINAL MEMBRANE | MESSENGER-RNA | GLUCOSE-TRANSPORTER | RESISTANCE-ASSOCIATED PROTEIN-1 | CHOROID-PLEXUS | MULTIDRUG TRANSPORTERS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Ependyma - blood supply | Cerebrovascular Circulation - physiology | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Choroid Plexus - metabolism | Glucose Transporter Type 1 - metabolism | Male | Gene Expression Profiling | Choroid Plexus - ultrastructure | Blood-Brain Barrier - ultrastructure | Microcirculation - physiology | Choroid Plexus - blood supply | Monocarboxylic Acid Transporters - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Blood-Brain Barrier - physiology | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Cell Line | Biotinylation | Rats | Ependyma - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Kidney - cytology | Rats, Sprague-Dawley | Blotting, Western | Symporters - metabolism | Animals | Glucose Transporter Type 1 - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Symporters - genetics | Microcirculation - ultrastructure | Monocarboxylic Acid Transporters - genetics | Multidrug Resistance-Associated Proteins - metabolism | Ependyma - ultrastructure | Phosphates | Glucose metabolism | Brain | Fluorescein | Biotin | Glucose | Drug resistance | Intermediate filament proteins | Dextrose | Protein binding
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 397 - 401
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e54442
.... SGLT2 inhibitors block reabsorption of filtered glucose by inhibiting SGLT2, the primary glucose transporter in the proximal tubular cell (PTC... 
MATRIX | STIMULATION | MULTIDISCIPLINARY SCIENCES | DISEASE | HIGH GLUCOSE | GENE-EXPRESSION | PPAR-GAMMA AGONISTS | TRANSFORMING GROWTH FACTOR-BETA | Diabetes Mellitus - pathology | Epithelial Cells - metabolism | Gene Expression - drug effects | Diabetes Mellitus - genetics | Transcription Factor AP-1 - genetics | Epithelial Cells - drug effects | Humans | Diabetic Nephropathies - drug therapy | NF-kappa B - metabolism | Smad3 Protein - metabolism | Transcription Factor AP-1 - metabolism | Sodium-Glucose Transporter 1 - genetics | Smad3 Protein - genetics | Sodium-Glucose Transporter 1 - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Transforming Growth Factor beta1 - pharmacology | Sodium-Glucose Transporter 2 - genetics | Collagen Type IV - metabolism | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Interleukin-6 - genetics | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Toll-Like Receptor 4 - genetics | Diabetic Nephropathies - genetics | Epithelial Cells - pathology | Glucose - pharmacology | Toll-Like Receptor 4 - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | NF-kappa B - genetics | Kidney Tubules, Proximal - metabolism | Collagen Type IV - genetics | Protein Binding | Benzhydryl Compounds - pharmacology | Kidney Tubules, Proximal - drug effects | Physiological aspects | Care and treatment | Genetic aspects | Research | Transforming growth factors | Diabetic nephropathies | Chromatin | Immunoprecipitation | Transforming growth factor-b | Interleukin | Clinical trials | Systematic review | Smad3 protein | Glucose | Kinases | Interleukin 6 | Proteins | Hyperglycemia | Rodents | Toll-like receptors | Collagen (type IV) | Hypoglycemic agents | Inhibition | Growth factors | Deoxyribonucleic acid--DNA | Immune system | Binding | Glucose transporter | Medical research | NF-κB protein | Diabetes mellitus | Markers | Activator protein 1 | Blocking | Reabsorption | Inflammation | Gene expression | Glucose transport | Medicine | High mobility group proteins | Hospitals | Inhibitors | Nephropathy | Sodium | Fibrosis | Kidney diseases | Diabetes | Transporter | Adenosine triphosphatase | Kidney transplantation | Deoxyribonucleic acid | DNA
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 11, p. e108994
Background and Objective: Sodium glucose cotransporter 2 (SGLT2) is the main luminal glucose transporter in the kidney... 
CELLS | HYPERGLYCEMIA | SGLT2 | TRANSPORTERS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | DISEASE | INJURY | PPAR-GAMMA AGONISTS | TRANSFORMING GROWTH FACTOR-BETA | PROGRESSION | Benzoates - therapeutic use | Toll-Like Receptor 2 - genetics | Diabetic Nephropathies - etiology | Transforming Growth Factor beta1 - metabolism | Glucose Transporter Type 1 - metabolism | Male | RNA, Messenger - metabolism | Nitric Oxide Synthase Type III - deficiency | Glucosides - therapeutic use | Chemokine CCL2 - metabolism | Diabetes Mellitus, Experimental - chemically induced | Diabetes Mellitus, Experimental - complications | Diabetes Mellitus, Experimental - metabolism | Benzhydryl Compounds - therapeutic use | Diabetic Nephropathies - prevention & control | Benzimidazoles - therapeutic use | Sodium-Glucose Transporter 2 - genetics | Hypoglycemic Agents - therapeutic use | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Albuminuria - etiology | Blood Glucose - analysis | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Chemokine CCL2 - genetics | Transforming Growth Factor beta1 - genetics | Toll-Like Receptor 2 - metabolism | Nitric Oxide Synthase Type III - genetics | Fibronectins - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | Mice, Knockout | Animals | Glucose Transporter Type 1 - genetics | Kidney Tubules, Proximal - metabolism | Benzoates - pharmacology | Benzimidazoles - pharmacology | Benzhydryl Compounds - pharmacology | Fibronectins - genetics | Mice | Streptozocin - toxicity | Blood Glucose - metabolism | Kidney Tubules, Proximal - drug effects | Drugs | Transcription | Syngeneic grafts | Streptozocin | Genomics | Transforming growth factor | Glucose | Macrophages | Blood | Fibronectin | Proteins | Atrophy | Hyperglycemia | Rodents | Toll-like receptors | Physiology | Inhibition | Protein transport | Immune system | Creatinine | Glucose transporter | Medical research | Kidneys | Cytokines | Diabetes mellitus | Reabsorption | Histology | Inflammation | Metabolism | Gene expression | Nephropathy | Sodium | Nitric oxide | Fibrosis | Angiotensin | Insulin resistance | Research design | Kidney diseases | Diabetes | Transporter | Monocyte chemoattractant protein 1 | Kidney transplantation | Best practice
Journal Article
PLoS biology, ISSN 1545-7885, 2018, Volume 16, Issue 4, p. e2002907
.... Here, we show that OCT1, widely characterized as a drug transporter, plays a key role in modulating hepatic glucose and lipid metabolism, potentially by mediating thiamine (vitamin B1... 
PYRUVATE-DEHYDROGENASE | SKELETAL-MUSCLE | GENETIC-VARIATION | LIPOPROTEIN | OBESITY | VARIANTS | FATTY-ACID OXIDATION | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | GENOME-WIDE | GLUCOSE-TOLERANCE | Ketone Oxidoreductases - metabolism | Liver - pathology | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Experimental - genetics | Thiamine Deficiency - genetics | Diabetes Mellitus, Type 2 - metabolism | Obesity - genetics | Cholesterol, LDL - blood | Lipid Metabolism - genetics | Diabetes Mellitus, Experimental - metabolism | Fatty Acids - metabolism | Signal Transduction | Liver - metabolism | Octamer Transcription Factor-1 - deficiency | Gene Expression Regulation | Octamer Transcription Factor-1 - genetics | Longevity - genetics | Ketone Oxidoreductases - genetics | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Thiamine - metabolism | Thiamine Deficiency - metabolism | Animals | Gluconeogenesis - genetics | Thiamine Deficiency - pathology | Triglycerides - blood | Cholesterol, HDL - blood | Diabetes Mellitus, Experimental - pathology | Mice | Diabetes Mellitus, Type 2 - pathology | Blood Glucose - metabolism | Vitamin B1 | Metabolism | Observations | Health aspects | Bioengineering | Lipoproteins (low density) | Adipose tissue | Pathogenesis | Liver | Lipids | Alcohol | Pyruvic acid | Genomes | Glucose | Glucose metabolism | Fatty liver | Metabolites | Vitamin B | Lipid metabolism | Diabetes mellitus (non-insulin dependent) | Thiamine | Pharmaceutical sciences | Gluconeogenesis | Obesity | Enzymes | Organic cation transporter | Nutrient deficiency | Diabetes mellitus | Health risks | Vitamin deficiency | Data processing | Histology | Pharmacology | Fatty acids | Low density lipoprotein | Cholesterol | Children & youth | Medicine | Microscopy | Cations | Gastrointestinal surgery | Diabetes | Cardiovascular diseases | Transporter | Metabolic disorders
Journal Article