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Journal Article
Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 20, pp. 4686 - 4697
Journal Article
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 06/2016, Volume 32, pp. 128 - 141
The present study has been designed and carried out to explore the role of grape seed proanthocyanidins (GSP) in the pancreas of cadmium (Cd)-induced cellular... 
Cadmium | Oxidative stress | Inflammation | Antioxidant | GSP | Apoptosis | ACTIVATION | ANTIOXIDANTS | CHOLESTEROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | FLAVONOIDS | ALLOXAN | NUTRITION & DIETETICS | SECRETION | EXPRESSION | NF-E2-Related Factor 2 - antagonists & inhibitors | Apoptosis - drug effects | Pancreatitis - etiology | Grape Seed Extract - adverse effects | Male | NF-E2-Related Factor 2 - agonists | Cadmium Chloride - administration & dosage | Glucose Transporter Type 2 - antagonists & inhibitors | Proanthocyanidins - administration & dosage | Cadmium Poisoning - pathology | Grape Seed Extract - administration & dosage | Biomarkers - metabolism | Hyperglycemia - prevention & control | Cytokines - agonists | Pancreas - pathology | Proanthocyanidins - therapeutic use | Biomarkers - blood | Pancreas - metabolism | Random Allocation | Glucose Transporter Type 4 - agonists | Pancreas - immunology | Proanthocyanidins - adverse effects | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | Hyperglycemia - etiology | Cadmium Poisoning - diet therapy | Oxidative Stress - drug effects | Cadmium Poisoning - metabolism | Glucose Transporter Type 2 - agonists | Grape Seed Extract - therapeutic use | Glucose Transporter Type 4 - metabolism | Rats, Wistar | Pancreatitis - prevention & control | Heme Oxygenase (Decyclizing) - chemistry | Glucose Transporter Type 2 - metabolism | Pancreatitis - immunology | Dietary Supplements - adverse effects | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Cytokines - blood | Glucose Transporter Type 4 - antagonists & inhibitors | Cytokines - metabolism | Pancreas - drug effects | Cadmium Poisoning - physiopathology | Antioxidants - therapeutic use | Animals | Antioxidants - administration & dosage | Antioxidants - adverse effects | Cytokines - antagonists & inhibitors | Blood sugar | Pancreatitis | Phosphates | Niacinamide | Isoenzymes | Low density lipoproteins | Zoology | Biological response modifiers | Ethylenediamines | Monosaccharides | Interleukins | Ligases | Nitric oxide | Heme | Lymphomas | Acetic acid | Sugars | Metallothionein | Interferon gamma | Organic compounds | Index Medicus
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 05/2016, Volume 38, Issue 5, pp. 2063 - 2078
Background/Aims: Type 2 Diabetes Mellitus (T2DM) is characterized by insulin resistance (IR), but the underlying molecular mechanisms are incompletely... 
Original Paper | MiR-27a | Phosphatidylinositol 3-kinase regulatory subunit beta | MTg-AMO | MiR-106b | MiR-30d | Mitogen-activated protein kinase 14 | Type 2 diabetes mellitus | Glucose transporter 4 | Insulin-resistant L6 cells | 3T3-L1 ADIPOCYTES | PHYSIOLOGY | TISSUE | SENSITIVITY | DIABETIC-RATS | CELL BIOLOGY | SKELETAL-MUSCLE | METABOLISM | Type 2 Diabetes Mellitus | FATTY LIVER | MICE | GLUCOSE-UPTAKE | MICRORNA EXPRESSION | MicroRNAs - antagonists & inhibitors | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Glucose Transporter Type 4 - metabolism | Rats, Wistar | Male | MicroRNAs - metabolism | Muscle, Skeletal - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | RNA, Messenger - metabolism | Mitogen-Activated Protein Kinase 14 - metabolism | Base Sequence | Diabetes Mellitus, Experimental - chemically induced | 3' Untranslated Regions | Diabetes Mellitus, Experimental - metabolism | Glucose Transporter Type 4 - antagonists & inhibitors | Cell Line | Glucose Transporter Type 4 - genetics | Signal Transduction | Down-Regulation | Insulin Resistance | Rats | Mitogen-Activated Protein Kinase 14 - genetics | Phosphatidylinositol 3-Kinases - genetics | Sequence Alignment | Animals | Diabetes Mellitus, Experimental - pathology | Glucose - metabolism | MicroRNAs - genetics | Antagomirs - metabolism | Index Medicus
Journal Article
Lipids in Health and Disease, ISSN 1476-511X, 09/2017, Volume 16, Issue 1, pp. 181 - 181
Background: Increased consumption of omega-3 (omega-3) fatty acids found in cold-water fish and fish oil has been reported to protect against obesity. A... 
Obesity | Adipocyte differentiation | Stearidonic acid | 3T3-L1 | Omega-3 fatty acids | ECHIUM OIL | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-3 FATTY-ACIDS | NUTRITION & DIETETICS | DOCOSAHEXAENOIC ACID | INSULIN-RESISTANCE | ENRICHED SOYBEAN-OIL | GENE-EXPRESSION | LINSEED OIL | RED-BLOOD-CELL | EICOSAPENTAENOIC ACID | ALPHA-LINOLENIC ACID | Fatty Acid Synthase, Type I - genetics | Lipoprotein Lipase - antagonists & inhibitors | Fatty Acid-Binding Proteins - antagonists & inhibitors | Glucose Transporter Type 4 - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - antagonists & inhibitors | Adipocytes - cytology | Adipocytes - drug effects | Fatty Acid-Binding Proteins - metabolism | PPAR gamma - metabolism | Fatty Acids, Omega-3 - pharmacology | CCAAT-Enhancer-Binding Proteins - antagonists & inhibitors | CCAAT-Enhancer-Binding Proteins - genetics | Lipoprotein Lipase - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | PPAR gamma - genetics | CCAAT-Enhancer-Binding Proteins - metabolism | Glucose Transporter Type 4 - antagonists & inhibitors | Cell Survival - drug effects | Glucose Transporter Type 4 - genetics | Lipoprotein Lipase - genetics | CCAAT-Enhancer-Binding Protein-beta - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | 3T3-L1 Cells | Fatty Acid Synthase, Type I - metabolism | Fatty Acid-Binding Proteins - genetics | Stearoyl-CoA Desaturase - genetics | CCAAT-Enhancer-Binding Protein-beta - metabolism | Fatty Acid Synthase, Type I - antagonists & inhibitors | Gene Expression Regulation - drug effects | Phosphoenolpyruvate Carboxykinase (ATP) - genetics | Animals | PPAR gamma - antagonists & inhibitors | Sterol Regulatory Element Binding Protein 1 - genetics | Cell Differentiation - drug effects | Adipocytes - metabolism | Phosphoenolpyruvate Carboxykinase (ATP) - metabolism | Lipid Metabolism - drug effects | Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors | Stearoyl-CoA Desaturase - metabolism | Mice | CCAAT-Enhancer-Binding Protein-beta - antagonists & inhibitors | Usage | Care and treatment | Analysis | Development and progression | Liquid chromatography | Glucose transporter | Vegetable oils | Soybeans | Transcription factors | Fish oils | Toxicity | Gene regulation | Preadipocytes | Mass spectroscopy | Stearoyl-CoA desaturase | Lipoprotein lipase | Adipocytes | Lipase | Desaturase | Gene expression | Fatty acids | Fatty-acid synthase | Polymerase chain reaction | Rodents | Down-regulation | Sterol regulatory element-binding protein | Index Medicus
Journal Article
Cell Biochemistry and Function, ISSN 0263-6484, 07/2013, Volume 31, Issue 5, pp. 374 - 379
The flavanone hesperetin is known to decrease basal glucose uptake, although the inhibitory mechanism is largely unknown. Here, we used MDA‐MB‐231 breast... 
GLUT1 | breast cancer cells | glucose uptake | GLUT4 | hesperetin | Glucose uptake | Hesperetin | Breast cancer cells | TRANSPORTER | INSULIN STIMULATION | PHOSPHATIDYLINOSITOL 3-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORANGE JUICE | PLASMA-MEMBRANE | CELL BIOLOGY | HEXOKINASE-II | FAT-CELLS | INTRACELLULAR DELIVERY | GLUT1 EXPRESSION | CARCINOMA | Phosphorylation | Glucose Transporter Type 4 - metabolism | Humans | Glucose Transporter Type 1 - metabolism | Antigens, CD - genetics | Proto-Oncogene Proteins c-akt - genetics | Antigens, CD - metabolism | Receptor, Insulin - genetics | Female | Biological Transport - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Flavones - pharmacology | Glucose Transporter Type 4 - antagonists & inhibitors | Glucose Transporter Type 4 - genetics | Signal Transduction | Receptor, Insulin - antagonists & inhibitors | Glucose Transporter Type 1 - genetics | Cell Line, Tumor | Glucose - metabolism | Hesperidin - pharmacology | Receptor, Insulin - metabolism | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Glucose Transporter Type 1 - antagonists & inhibitors | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Glucose metabolism | Breast cancer | Glucose | Dextrose | Cancer cells | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 2477 - 14
Adipose tissue is a specialized organ that synthesizes and stores fat. During adipogenesis, Rho and Rho-associated kinase (ROCK) 2 are inactivated, which... 
ACTIVATED RECEPTOR-GAMMA | STIMULATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | ROCK-I | RHO-KINASE INHIBITOR | ADIPOCYTE DIFFERENTIATION | ACTIN CYTOSKELETON | BINDING | MESENCHYMAL STEM-CELLS | INDUCED INSULIN-RESISTANCE | Fatty Acid-Binding Proteins - antagonists & inhibitors | Glucose Transporter Type 4 - metabolism | Adipogenesis - drug effects | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Adipocytes - cytology | Adipocytes - drug effects | Fatty Acid-Binding Proteins - metabolism | PPAR gamma - metabolism | Heterocyclic Compounds, 4 or More Rings - pharmacology | rho-Associated Kinases - antagonists & inhibitors | rho-Associated Kinases - metabolism | Actin Cytoskeleton - drug effects | CCAAT-Enhancer-Binding Proteins - antagonists & inhibitors | Cell Differentiation | CCAAT-Enhancer-Binding Proteins - genetics | Adipogenesis - genetics | PPAR gamma - genetics | Amides - pharmacology | CCAAT-Enhancer-Binding Proteins - metabolism | Glucose Transporter Type 4 - antagonists & inhibitors | Actin Cytoskeleton - metabolism | Glucose Transporter Type 4 - genetics | Signal Transduction | Gene Expression Regulation | rho-Associated Kinases - genetics | 3T3-L1 Cells | Fatty Acid-Binding Proteins - genetics | Animals | PPAR gamma - antagonists & inhibitors | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Adipocytes - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Actin Cytoskeleton - ultrastructure | Anti-Obesity Agents - pharmacology | Transcription factors | Adipose tissue | Actin | Rho-associated kinase | Adipogenesis | Fibers | Index Medicus
Journal Article
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 2015, Volume 308, Issue 4, pp. E294 - E305
Insulin stimulates glucose uptake in adult skeletal muscle by promoting the translocation of GLUT4 glucose transporters to the transverse tubule (T-tubule)... 
Diabetes | Calcium | Glucose transporter 4 | High-fat diet | Transverse tubules | Ryanodine receptor | CELLS | TRANSLOCATION | PHYSIOLOGY | calcium | CA2+ RELEASE | TRAFFICKING | transverse tubules | glucose transporter 4 | AKT INHIBITOR | PLASMA-MEMBRANE | TRANSVERSE TUBULE MEMBRANES | TRANSPORT | high-fat diet | ENDOCRINOLOGY & METABOLISM | MAMMALIAN SKELETAL-MUSCLE | ryanodine receptor | diabetes | DEPENDENT MECHANISM | Glucose Transporter Type 4 - metabolism | Obesity - drug therapy | Male | Ryanodine Receptor Calcium Release Channel - metabolism | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | beta-Cyclodextrins - pharmacology | Protein Processing, Post-Translational - drug effects | Membrane Transport Modulators - pharmacology | Biological Transport - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Glucose Transporter Type 4 - antagonists & inhibitors | Insulin - pharmacology | Insulin - agonists | Hypoglycemic Agents - agonists | Mice, Inbred C57BL | Cells, Cultured | Insulin Resistance | Ryanodine Receptor Calcium Release Channel - drug effects | Cholesterol - metabolism | Glucose Transporter Type 4 - agonists | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | Obesity - metabolism | Obesity - pathology | Animals | Anticholesteremic Agents - therapeutic use | beta-Cyclodextrins - therapeutic use | Muscle Fibers, Skeletal - pathology | Glucose - metabolism | Protein Kinase Inhibitors - pharmacology | Anticholesteremic Agents - pharmacology | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 02/2018, Volume 338, pp. 32 - 39
The insulin-regulated glucose transporter, GluT4, is a key molecule in peripheral insulin signaling. Although GluT4 is abundantly expressed in neurons of... 
Glucose transporter | Insulin | Memory | Hippocampus |