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Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7394, pp. 333 - 338
The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a... 
DIABETES-MELLITUS | FATTY-ACID SYNTHESIS | GENE | INSULIN-RESISTANCE | LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | CARBOHYDRATE-RESPONSE ELEMENT | LIVER | BINDING-PROTEIN CHREBP | UCSC GENOME BROWSER | TRANSGENIC MICE | Transcription Factors - chemistry | Diabetes Mellitus - genetics | Humans | Male | RNA, Messenger - metabolism | Adipose Tissue - metabolism | Protein Isoforms - chemistry | Nuclear Proteins - deficiency | Lipogenesis | Body Mass Index | Glucose Transporter Type 4 - genetics | Adipose Tissue - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Genotype | Glucose - pharmacology | Nuclear Proteins - chemistry | Mice, Knockout | Insulin - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Insulin Resistance - genetics | Glucose - metabolism | Mice | Blood Glucose - metabolism | Homeostasis - genetics | Cohort Studies | Diabetes Mellitus - blood | Body Weight | Glucose Transporter Type 4 - metabolism | Transcription Factors - deficiency | Adipose Tissue - cytology | Molecular Sequence Data | Obesity - genetics | Promoter Regions, Genetic - genetics | Protein Isoforms - metabolism | Adiposity | Female | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Intolerance - genetics | Cross-Sectional Studies | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Diabetes Mellitus - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Glucose Transporter Type 4 - biosynthesis | Adipocytes - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Isoforms - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 258 - 262
In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes(1). Adipose-specific knockout or overexpression of... 
OXIDATIVE STRESS | METABOLISM | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | LIVER | MOUSE | MICE | CDNA CLONING | EXPRESSION | SIRT1 | ADIPOSE-TISSUE | Sirtuin 1 - metabolism | Acetyltransferases - metabolism | Adipocytes - secretion | Ornithine Decarboxylase - metabolism | Liver - enzymology | Glucose Transporter Type 4 - metabolism | Adipose Tissue, White - metabolism | Male | Diabetes Mellitus, Type 2 - metabolism | Nicotinamide N-Methyltransferase - metabolism | Glucose Intolerance | Glucose Transporter Type 4 - deficiency | Obesity - genetics | Thinness - metabolism | Gene Knockdown Techniques | Adipose Tissue - metabolism | Nicotinamide N-Methyltransferase - deficiency | Obesity - etiology | NAD - metabolism | Spermine - analogs & derivatives | Nicotinamide N-Methyltransferase - genetics | Thinness - enzymology | Glucose Transporter Type 4 - genetics | Niacinamide - metabolism | Mice, Inbred C57BL | Diabetes Mellitus, Type 2 - enzymology | Insulin Resistance | Oxidoreductases Acting on CH-NH Group Donors - metabolism | Fatty Liver | Animals | Diet | Energy Metabolism | Adipocytes - metabolism | Obesity - prevention & control | Spermine - metabolism | Adipose Tissue, White - enzymology | Adipose Tissue - enzymology | Mice | Obesity - enzymology | S-Adenosylmethionine - metabolism | Adipose tissues | Type 2 diabetes | Obesity | Care and treatment | Analysis | Transferases | Physiological aspects | Genetic aspects | Research | Gene expression | Enzymes | Body fat | Adipocytes | Polyamines | Variance analysis | Proteins | Weight control | Metabolites | Rodents | Insulin resistance | Diabetes | Mass spectrometry | Food | Index Medicus
Journal Article
Journal Article
Blood, ISSN 0006-4971, 05/2012, Volume 119, Issue 20, pp. 4686 - 4697
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 15, pp. 1517 - 1526
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2015, Volume 35, Issue 14, pp. 5851 - 5859
Alzheimer's disease (AD) is a neurological disorder characterized by profound memory loss and progressive dementia. Accumulating evidence suggests that Type 2... 
Glucose metabolism | Alzheimer’s disease | LRP1 | Apolipoprotein e | Insulin signaling | FDG-PET | IMPROVES COGNITION | ALZHEIMERS-DISEASE | CELL-SURFACE | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | APOLIPOPROTEIN-E | insulin signaling | GENE | AMYLOID-BETA | apolipoprotein E | Alzheimer's disease | glucose metabolism | RECEPTOR-RELATED PROTEIN-1 | GROWTH-FACTOR EXPRESSION | Glucose Transporter Type 4 - metabolism | Blood-Brain Barrier - physiopathology | Diabetes Mellitus, Experimental - genetics | Glucose Transporter Type 3 - metabolism | Brain - metabolism | Glucose Transporter Type 3 - genetics | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Receptors, LDL - deficiency | Neurons - metabolism | Neurons - drug effects | RNA Interference - physiology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Disease Models, Animal | Insulin - pharmacology | Receptors, LDL - genetics | Glucose Intolerance - genetics | Glucose Transporter Type 4 - genetics | Gene Expression Regulation - genetics | Brain - physiopathology | Mice, Transgenic | Signal Transduction - genetics | Blood-Brain Barrier - drug effects | Protein Transport - genetics | Gene Expression Regulation - drug effects | Insulin - metabolism | Animals | Signal Transduction - drug effects | Brain - pathology | Diabetes Mellitus, Experimental - pathology | Glucose - metabolism | Mice | Cell Line, Transformed | Index Medicus
Journal Article
Journal Article
Cell, ISSN 0092-8674, 10/2014, Volume 159, Issue 2, pp. 318 - 332
Journal Article
Journal Article