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Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 258 - 262
In obesity and type 2 diabetes, Glut4 glucose transporter expression is decreased selectively in adipocytes(1). Adipose-specific knockout or overexpression of... 
OXIDATIVE STRESS | METABOLISM | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | LIVER | MOUSE | MICE | CDNA CLONING | EXPRESSION | SIRT1 | ADIPOSE-TISSUE | Sirtuin 1 - metabolism | Acetyltransferases - metabolism | Adipocytes - secretion | Ornithine Decarboxylase - metabolism | Liver - enzymology | Glucose Transporter Type 4 - metabolism | Adipose Tissue, White - metabolism | Male | Diabetes Mellitus, Type 2 - metabolism | Nicotinamide N-Methyltransferase - metabolism | Glucose Intolerance | Glucose Transporter Type 4 - deficiency | Obesity - genetics | Thinness - metabolism | Gene Knockdown Techniques | Adipose Tissue - metabolism | Nicotinamide N-Methyltransferase - deficiency | Obesity - etiology | NAD - metabolism | Spermine - analogs & derivatives | Nicotinamide N-Methyltransferase - genetics | Thinness - enzymology | Glucose Transporter Type 4 - genetics | Niacinamide - metabolism | Mice, Inbred C57BL | Diabetes Mellitus, Type 2 - enzymology | Insulin Resistance | Oxidoreductases Acting on CH-NH Group Donors - metabolism | Fatty Liver | Animals | Diet | Energy Metabolism | Adipocytes - metabolism | Obesity - prevention & control | Spermine - metabolism | Adipose Tissue, White - enzymology | Adipose Tissue - enzymology | Mice | Obesity - enzymology | S-Adenosylmethionine - metabolism | Adipose tissues | Type 2 diabetes | Obesity | Care and treatment | Analysis | Transferases | Physiological aspects | Genetic aspects | Research | Gene expression | Enzymes | Body fat | Adipocytes | Polyamines | Variance analysis | Proteins | Weight control | Metabolites | Rodents | Insulin resistance | Diabetes | Mass spectrometry | Food | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2006, Volume 354, Issue 24, pp. 2552 - 2563
In this study, serum levels of retinol-binding protein 4, a molecule secreted by adipocytes, correlated with the magnitude of insulin resistance in subjects... 
METABOLIC DEFECTS | MEDICINE, GENERAL & INTERNAL | PLASMA-CONCENTRATIONS | GLUCOSE | RETINOL-BINDING-PROTEIN | HYPERINSULINEMIA | ADIPOSITY | DYSLIPIDEMIA | CORONARY-HEART-DISEASE | FAT DISTRIBUTION | NIDDM | Cross-Sectional Studies | Glucose Transporter Type 4 - metabolism | Retinol-Binding Proteins, Plasma | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Obesity - blood | Thinness - metabolism | Obesity - metabolism | Metabolic Syndrome - blood | Diabetes Mellitus, Type 2 - blood | Retinol-Binding Proteins - metabolism | Insulin Resistance - physiology | Adipocytes - metabolism | Glucose Metabolism Disorders - metabolism | Thinness - blood | Glucose Metabolism Disorders - blood | Adult | Female | Exercise - physiology | Blood Glucose - metabolism | Insulin resistance | Diabetes | Glucose | Insulin | Rodents | Index Medicus | Abridged Index Medicus | Obesity/blood/metabolism | Blood Glucose/metabolism | Adipocytes/metabolism | Thinness/blood/metabolism | Exercise/physiology | MEDICIN OCH HÄLSOVETENSKAP | Diabetes Mellitus | Glucose Transporter Type 4/metabolism | Type 2/blood/genetics/metabolism | Glucose Metabolism Disorders/blood/metabolism | Insulin Resistance/physiology | Metabolic Syndrome X/blood | Retinol-Binding Proteins/metabolism | MEDICAL AND HEALTH SCIENCES
Journal Article
Nature, ISSN 0028-0836, 04/2012, Volume 484, Issue 7394, pp. 333 - 338
The prevalence of obesity and type 2 diabetes is increasing worldwide and threatens to shorten lifespan. Impaired insulin action in peripheral tissues is a... 
DIABETES-MELLITUS | FATTY-ACID SYNTHESIS | GENE | INSULIN-RESISTANCE | LIPOGENESIS | MULTIDISCIPLINARY SCIENCES | CARBOHYDRATE-RESPONSE ELEMENT | LIVER | BINDING-PROTEIN CHREBP | UCSC GENOME BROWSER | TRANSGENIC MICE | Transcription Factors - chemistry | Diabetes Mellitus - genetics | Humans | Male | RNA, Messenger - metabolism | Adipose Tissue - metabolism | Protein Isoforms - chemistry | Nuclear Proteins - deficiency | Lipogenesis | Body Mass Index | Glucose Transporter Type 4 - genetics | Adipose Tissue - pathology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Genotype | Glucose - pharmacology | Nuclear Proteins - chemistry | Mice, Knockout | Insulin - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Insulin Resistance - genetics | Glucose - metabolism | Mice | Blood Glucose - metabolism | Homeostasis - genetics | Cohort Studies | Diabetes Mellitus - blood | Body Weight | Glucose Transporter Type 4 - metabolism | Transcription Factors - deficiency | Adipose Tissue - cytology | Molecular Sequence Data | Obesity - genetics | Promoter Regions, Genetic - genetics | Protein Isoforms - metabolism | Adiposity | Female | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Intolerance - genetics | Cross-Sectional Studies | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Cells, Cultured | Diabetes Mellitus - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Glucose Transporter Type 4 - biosynthesis | Adipocytes - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Protein Isoforms - genetics | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 10/2014, Volume 159, Issue 2, pp. 318 - 332
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The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 15, pp. 1517 - 1526
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