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humans (178) 178
glucosylceramidase - antagonists & inhibitors (162) 162
science & technology (137) 137
life sciences & biomedicine (124) 124
glucosylceramidase - metabolism (104) 104
animals (81) 81
gaucher disease - enzymology (69) 69
gaucher disease (65) 65
enzyme inhibitors - pharmacology (64) 64
glucosylceramidase - genetics (59) 59
gaucher disease - drug therapy (55) 55
biochemistry & molecular biology (53) 53
mice (48) 48
mutation (46) 46
biological and medical sciences (44) 44
inositol - analogs & derivatives (41) 41
enzyme inhibitors - chemistry (40) 40
enzymes (39) 39
cells, cultured (36) 36
female (36) 36
gaucher disease - genetics (36) 36
inositol - pharmacology (36) 36
medical sciences (36) 36
glucocerebrosidase (32) 32
kinetics (32) 32
male (31) 31
gaucher disease - pathology (28) 28
glucosylceramides - metabolism (28) 28
lipids (28) 28
gaucher disease - metabolism (27) 27
lysosomes - enzymology (27) 27
cell line (26) 26
gaucher's disease (26) 26
enzyme inhibitors - chemical synthesis (25) 25
fibroblasts - enzymology (24) 24
glucosylceramidase - chemistry (24) 24
structure-activity relationship (24) 24
glucosyltransferases - antagonists & inhibitors (23) 23
metabolic diseases (23) 23
1-deoxynojirimycin - analogs & derivatives (22) 22
fibroblasts - drug effects (22) 22
glucosylceramidase (22) 22
chemistry (21) 21
genetics & heredity (21) 21
medicine, research & experimental (21) 21
research & experimental medicine (21) 21
beta-glucosidase - antagonists & inhibitors (20) 20
binding sites (20) 20
enzyme inhibitors - therapeutic use (20) 20
errors of metabolism (20) 20
glucosylceramidase - therapeutic use (20) 20
pharmacology & pharmacy (20) 20
hematology (17) 17
research article (17) 17
endocrinology & metabolism (16) 16
chemistry, medicinal (15) 15
lysosomes - metabolism (15) 15
hydrogen-ion concentration (14) 14
models, molecular (14) 14
rats (14) 14
substrate specificity (14) 14
cell biology (13) 13
enzyme replacement therapy (13) 13
glucosidases - antagonists & inhibitors (13) 13
glucosylceramidase - deficiency (13) 13
liver - enzymology (13) 13
middle aged (13) 13
parkinson's disease (13) 13
spleen - enzymology (13) 13
adult (12) 12
beta-glucosidase - metabolism (12) 12
disease models, animal (12) 12
glucosidases - metabolism (12) 12
glucosyltransferases - metabolism (12) 12
hydrolases (12) 12
inhibitors (12) 12
neurosciences & neurology (12) 12
physical sciences (12) 12
protein binding (12) 12
1-deoxynojirimycin - pharmacology (11) 11
1-deoxynojirimycin - therapeutic use (11) 11
abridged index medicus (11) 11
catalytic domain (11) 11
fibroblasts (11) 11
glucosylceramide (11) 11
inhibitory concentration 50 (11) 11
internal medicine (11) 11
medicine (11) 11
molecular sequence data (11) 11
multidisciplinary sciences (11) 11
neurosciences (11) 11
saposins (11) 11
science & technology - other topics (11) 11
aged (10) 10
amino acid sequence (10) 10
analysis (10) 10
drug design (10) 10
fundamental and applied biological sciences. psychology (10) 10
gaucher disease - diagnosis (10) 10
gaucher disease - therapy (10) 10
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