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Materials Science & Engineering C, ISSN 0928-4931, 04/2016, Volume 61, pp. 616 - 630
Nano-drug delivery systems are being widely explored to overcome the challenges with existing antibiotics to treat bacterial infections [1]. Lipid–polymer... 
In silico | Vancomycin | Antibacterial | Lipid–polymer | Nanoparticle | MRSA | Lipid-polymer | MUCOADHESIVE BEADS | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | SHELL NANOPARTICLES | CHITOSAN NANOPARTICLES | SILVER NANOPARTICLES | ANTIBACTERIAL ACTIVITY | PHYSICOCHEMICAL CHARACTERIZATION | ORAL BIOAVAILABILITY | OCULAR DELIVERY | TOPICAL DELIVERY | Models, Chemical | Nanoparticles - chemistry | Delayed-Action Preparations - chemistry | Acrylic Resins - pharmacology | Hexuronic Acids - pharmacokinetics | Triglycerides - chemistry | Vancomycin - chemistry | Oleic Acid - pharmacology | Acrylic Resins - pharmacokinetics | Delayed-Action Preparations - pharmacology | Vancomycin - pharmacology | Delayed-Action Preparations - pharmacokinetics | Chitosan - pharmacology | Oleic Acid - pharmacokinetics | Triglycerides - pharmacology | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Alginates - pharmacology | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Acrylic Resins - chemistry | Triglycerides - pharmacokinetics | Glucuronic Acid - pharmacology | Chitosan - chemistry | Vancomycin - pharmacokinetics | Chitosan - pharmacokinetics | Alginates - chemistry | Kinetics | Oleic Acid - chemistry | Hexuronic Acids - pharmacology | Drugs | Nanoparticles | Monounsaturated fatty acids | Drug delivery systems | Bacterial infections | Biomimetics | Lipids | Polymer industry | Polymers | Vehicles | Bacteria | In vitro testing | Nanostructure
Journal Article
Biomacromolecules, ISSN 1525-7797, 09/2014, Volume 15, Issue 9, pp. 3246 - 3252
Multifunctional injectable thermo-/pH-responsive hydrogels as release systems for the oral delivery of small molecule drugs and the local delivery of protein... 
POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | COENZYME-A | MECHANICAL-PROPERTIES | BIODEGRADABLE HYDROGELS | IN-VITRO | CHITOSAN MATERIAL | PH | RECENT PROGRESS | SYSTEMS | BIOMEDICAL APPLICATIONS | ORAL DELIVERY | Diclofenac - pharmacology | Adipose Tissue - cytology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Delayed-Action Preparations - chemistry | Hydrogels - pharmacokinetics | Hydrogels - chemical synthesis | Hexuronic Acids - pharmacokinetics | Methacrylates - chemistry | Diclofenac - chemistry | Drug Carriers - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Adipose Tissue - metabolism | Mesenchymal Stromal Cells - cytology | Cattle | Delayed-Action Preparations - pharmacology | Delayed-Action Preparations - pharmacokinetics | Delayed-Action Preparations - chemical synthesis | Serum Albumin, Bovine - chemistry | Hexuronic Acids - chemical synthesis | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Glucuronic Acid - chemical synthesis | Alginates - pharmacology | Rabbits | Serum Albumin, Bovine - pharmacology | Mesenchymal Stromal Cells - metabolism | Drug Carriers - chemical synthesis | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Diclofenac - pharmacokinetics | Drug Carriers - pharmacology | Glucuronic Acid - pharmacology | Serum Albumin, Bovine - pharmacokinetics | Animals | Alginates - chemical synthesis | Alginates - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Drug Carriers - pharmacokinetics | Hydrogels - pharmacology | Hydrogels - chemistry | Hexuronic Acids - pharmacology | Hydrogen-Ion Concentration
Journal Article
Annals of Biomedical Engineering, ISSN 0090-6964, 1/2017, Volume 45, Issue 1, pp. 297 - 305
Controlled drug delivery systems, that include sequential and/or sustained drug delivery, have been utilized to enhance the therapeutic effects of many current... 
Biomedicine, general | Biomedical Engineering | Biochemistry, general | Controlled delivery | Biomedicine | PLGA | Composite materials | Classical Mechanics | Differential delivery | Alginate | Biological and Medical Physics, Biophysics | Extrusion printing | SYSTEM | ENGINEERING, BIOMEDICAL | TISSUE | RELEASE PROFILES | TABLETS | MATRICES | BONE REGENERATION | MULTIPLE-DRUGS | Alginates - pharmacology | Fluorescent Dyes - chemistry | Fluorescent Dyes - pharmacokinetics | Lactic Acid - chemistry | Humans | Polyglycolic Acid - pharmacology | Delayed-Action Preparations - chemistry | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Hexuronic Acids - pharmacokinetics | Lactic Acid - pharmacokinetics | Glucuronic Acid - pharmacology | Polyglycolic Acid - pharmacokinetics | Alginates - chemistry | Delayed-Action Preparations - pharmacology | Polyglycolic Acid - chemistry | Delayed-Action Preparations - pharmacokinetics | HEK293 Cells | Fluorescent Dyes - pharmacology | Glucuronic Acid - chemistry | Lactic Acid - pharmacology | Printing, Three-Dimensional | Alginates - pharmacokinetics | Hexuronic Acids - pharmacology | Drugs | Proteins | Drug delivery systems | Pharmacy | Therapeutics | Stem cells | Computer-aided design | 3D printing | Homeopathy | Materia medica and therapeutics | Vehicles | Biomedical engineering | Sequential delivery | Toxicity | Control systems | Tubes | Devices | Controlled Delivery | Differential Delivery | Composite Materials
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12722 - 12727
Local drug delivery depots have significant clinical utility, but there is currently no noninvasive technique to refill these systems once their payload is... 
Nanoparticles | Gels | Calcium | Hydrogels | Antineoplastics | Fluorescence | Alginates | Polymers | Pharmacokinetics | Tumors | DNA nanotechnology | Targeting | Nanoparticle | Controlled release | Biomaterials | ALGINATE | MULTIDISCIPLINARY SCIENCES | nanoparticle | BIODISTRIBUTION | THERAPEUTIC ANGIOGENESIS | TUMORS | CANCER-THERAPY | NUCLEIC-ACIDS | NANOPARTICLES | targeting | controlled release | L-DNA | PHARMACOKINETICS | IN-VIVO | biomaterials | Doxorubicin - blood | Neoplasm Transplantation | Injections, Intravenous | Humans | Melanoma, Experimental - drug therapy | Hydrogels - pharmacokinetics | Hexuronic Acids - pharmacokinetics | Antibiotics, Antineoplastic - blood | Oligodeoxyribonucleotides - blood | Injections, Intralesional | Tumor Cells, Cultured | Antibiotics, Antineoplastic - pharmacokinetics | Hydrazones - pharmacokinetics | Alginates - pharmacokinetics | Disease Models, Animal | Hydrazones - blood | Hexuronic Acids - blood | Mice, Inbred C57BL | Glucuronic Acid - blood | Glucuronic Acid - pharmacokinetics | Breast Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Oligodeoxyribonucleotides - pharmacokinetics | Mice | Drug Delivery Systems - methods | Drugs | Pharmaceutical research | Drug delivery systems | Research | Drug interactions | Vehicles | Biological Sciences | Physical Sciences
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 2010, Volume 74, Issue 2, pp. 332 - 339
Ciprofloxacin hydrochloride has a short elimination half-life, a narrow absorption window and is mainly absorbed in proximal areas of GIT. The purpose of this... 
Abdominal X-ray imaging | Gas former | Ciprofloxacin hydrochloride | Release-retarding polymers | Floating gastroretentive tablets | POLYMERS | MICROSPHERES | BEHAVIOR | DRUG-DELIVERY SYSTEM | FORMULATION | ANTIBACTERIAL ACTIVITY | PHARMACOLOGY & PHARMACY | GASTRIC RETENTION | Humans | Tablets - pharmacokinetics | Contrast Media - pharmacokinetics | Methylcellulose - analogs & derivatives | Delayed-Action Preparations - chemistry | Male | Barium Sulfate - pharmacokinetics | Stomach - metabolism | Hexuronic Acids - pharmacokinetics | Calcium Carbonate - chemistry | Delayed-Action Preparations - administration & dosage | Methylcellulose - pharmacokinetics | Time Factors | Chemical Phenomena | Delayed-Action Preparations - pharmacokinetics | Adult | Delayed-Action Preparations - chemical synthesis | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Radiography, Abdominal | Stomach - diagnostic imaging | Tablets - administration & dosage | Drug Compounding - methods | Drug Stability | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Ciprofloxacin - pharmacokinetics | Methylcellulose - chemistry | Tablets - chemical synthesis | Hypromellose Derivatives | Alginates - chemistry | Tablets - chemistry | Sodium Bicarbonate - chemistry | Drugs | Barium | Drug delivery systems | Salts | Limestone | Sodium bicarbonate | Carbonates | Polymers | Ciprofloxacin | Sulfates | Vehicles
Journal Article
Journal Article
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 06/2013, Volume 57, pp. 174 - 184
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 12/2012, Volume 8, Issue 1, pp. 23 - 32
This study aimed to prepare nanoemulsions coated with alginate/chitosan for oral insulin delivery. Uncoated nanoemulsions were prepared by homogenization of a... 
Alginate | Chitosan | Insulin | Nanoemulsion | Oral delivery | alginate | VITRO | chitosan | PROTEIN | insulin | MICROSPHERES | LECITHIN-BASED MICROEMULSION | NANOSCIENCE & NANOTECHNOLOGY | IONOTROPIC PRE-GELATION | nanoemulsion | PEPTIDE | NANOPARTICLES | oral delivery | PHARMACOLOGY & PHARMACY | PARTICLE-SIZE | LIPOSOMES | Diabetes Mellitus, Experimental - drug therapy | Nanoparticles - chemistry | Rats, Wistar | Drug Carriers - administration & dosage | Hexuronic Acids - administration & dosage | Male | Hexuronic Acids - pharmacokinetics | Drug Carriers - chemistry | Diabetes Mellitus, Experimental - blood | Emulsions - administration & dosage | Hypoglycemic Agents - administration & dosage | Glucuronic Acid - administration & dosage | Diabetes Mellitus, Experimental - metabolism | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Circular Dichroism | Hypoglycemic Agents - pharmacokinetics | Administration, Oral | Emulsions - chemistry | Drug Stability | Gastric Juice - metabolism | Chitosan - administration & dosage | Rats | Insulin - administration & dosage | Hypoglycemic Agents - chemistry | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Blood Glucose - drug effects | Particle Size | Alginates - administration & dosage | Animals | Chitosan - chemistry | Analysis of Variance | Chitosan - pharmacokinetics | Insulin - chemistry | Models, Biological | Alginates - chemistry | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Blood Glucose - metabolism | Emulsions - pharmacokinetics | Insulin - pharmacokinetics | Drugs | Drug delivery systems | Chitin | Research | Health aspects | Vehicles | Nanoemulsions | Diabetes | Rodents | Leakage | Spectroscopy | Particle size | Alginic acid | Diabetes mellitus | Oral administration | Polyelectrolytes | Phospholipids | Bioavailability | Coatings | Stress | Calcium chloride | Oil | C.D | nanotechnology | Gastric juice | Original Research
Journal Article
Annals of Biomedical Engineering, ISSN 0090-6964, 4/2017, Volume 45, Issue 4, pp. 1003 - 1014
Sphingosine-1-phosphate (S1P), a bioactive lipid, is a potent candidate for treatment of ischemic vascular disease. However, designing biomaterial systems for... 
Biomedicine, general | Biochemistry, general | Classical Mechanics | Lipid | Proangiogenic factors | Biomedical Engineering | Homing | Composite hydrogel | Sphingosine-1-phosphate (S1P) | Biomedicine | Biological and Medical Physics, Biophysics | Controlled release | Outgrowth endothelial cell | DRUG | ENGINEERING, BIOMEDICAL | RELEASE | SPHINGOSINE 1-PHOSPHATE | DELIVERY | BEADS | ENDOTHELIAL PROGENITOR CELLS | IN-VIVO | BIOMEDICAL APPLICATIONS | GROWTH-FACTOR | SCAFFOLDS | Lysophospholipids - pharmacokinetics | Neovascularization, Physiologic - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Delayed-Action Preparations - chemistry | Hydrogels - pharmacokinetics | Hexuronic Acids - pharmacokinetics | Delayed-Action Preparations - pharmacology | Delayed-Action Preparations - pharmacokinetics | Lysophospholipids - pharmacology | Chitosan - pharmacology | Glucuronic Acid - chemistry | Alginates - pharmacokinetics | Alginates - pharmacology | Lysophospholipids - chemistry | Sphingosine - pharmacokinetics | Cells, Cultured | Glucuronic Acid - pharmacokinetics | Hexuronic Acids - chemistry | Sphingosine - pharmacology | Glucuronic Acid - pharmacology | Sphingosine - analogs & derivatives | Chitosan - chemistry | Chitosan - pharmacokinetics | Alginates - chemistry | Hydrogels - pharmacology | Hydrogels - chemistry | Sphingosine - chemistry | Hexuronic Acids - pharmacology | Phosphates | Blood circulation disorders | Biological products | Sphingosine | Neovascularization | Health aspects | Biomedical engineering | Endothelium | Surgical implants | Gels | Hydrogels | Medical services | Lipids | Alginates | Chitosan
Journal Article
Journal of Microencapsulation, ISSN 0265-2048, 3/2015, Volume 32, Issue 2, pp. 151 - 156
Journal Article