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Clinical Chemistry and Laboratory Medicine (CCLM), ISSN 1434-6621, 12/2014, Volume 52, Issue 12, pp. 1823 - 1833
Journal Article
Journal Article
Journal Article
Journal Article
BIOANALYSIS, ISSN 1757-6180, 2015, Volume 7, Issue 6, pp. 653 - 659
Aims: A cross-laboratory experiment has been performed on a novel dried blood sampler in order to investigate whether it overcomes issues associated with blood... 
CONSORTIUM | LC-MS/MS | CHEMISTRY, ANALYTICAL | SAMPLE COLLECTION | GLUCURONIDE | SPOTS | STABILITY | BIOCHEMICAL RESEARCH METHODS | UPDATE | ASSAY BIAS | DBS ANALYSIS | DISCOVERY
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2016, Volume 44, Issue 1, pp. 151 - 161
Efavirenz (EFV) is principally metabolized by CYP2B6 to 8-hydroxy-efavirenz (8OH-EFV) and to a lesser extent by CYP2A6 to 7-hydroxy-efavirenz (7OH-EFV). So... 
400 MG | TRIAL | THERAPY | CYP2B6 | HIV | MORPHINE | LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY | MORPHINE-6-GLUCURONIDE | PHARMACOLOGY & PHARMACY | ACTIVE-TRANSPORT | BLOOD-BRAIN-BARRIER | Neurotoxicity Syndromes - genetics | Reverse Transcriptase Inhibitors - blood | Humans | Anti-HIV Agents - cerebrospinal fluid | Glucuronides - cerebrospinal fluid | Cytochrome P-450 CYP2B6 - metabolism | Glucuronides - blood | Reverse Transcriptase Inhibitors - adverse effects | Tandem Mass Spectrometry | Reverse Transcriptase Inhibitors - pharmacokinetics | Benzoxazines - urine | Cytochrome P-450 CYP3A - genetics | Benzoxazines - pharmacokinetics | Sulfates - blood | HIV Infections - diagnosis | Benzoxazines - blood | Anti-HIV Agents - blood | Reverse Transcriptase Inhibitors - urine | Metabolic Detoxication, Phase II | Hydroxylation | Risk Assessment | Cytochrome P-450 CYP2A6 - genetics | Cytochrome P-450 CYP2B6 - genetics | Anti-HIV Agents - adverse effects | Benzoxazines - cerebrospinal fluid | Benzoxazines - adverse effects | Cytochrome P-450 CYP2A6 - metabolism | Genotype | Glucuronides - urine | Anti-HIV Agents - urine | Reverse Transcriptase Inhibitors - cerebrospinal fluid | Sulfates - cerebrospinal fluid | Metabolomics - methods | Neurotoxicity Syndromes - etiology | Phenotype | Sulfates - urine | Cytochrome P-450 CYP3A - metabolism | Anti-HIV Agents - pharmacokinetics | Metabolic Detoxication, Phase I | Neurotoxicity Syndromes - metabolism | HIV Infections - drug therapy | HIV Infections - metabolism | Index Medicus
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2001, Volume 134, Issue 8, pp. 1796 - 1804
Journal Article