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1. Full Text Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells
by Jakubíková, Jana and Sedlák, Ján and Mithen, Richard and Bao, Yongping
Biochemical pharmacology, ISSN 0006-2952, 06/2005, Volume 69, Issue 11, pp. 1543 - 1552
Isothiocyanate | Chemotherapeutics | Signaling pathway | Cell cycle | Apoptosis | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Transcription, Genetic - drug effects | MAP Kinase Signaling System - physiology | Humans | NAD(P)H Dehydrogenase (Quinone) - genetics | G2 Phase - drug effects | Glucuronosyltransferase - genetics | Membrane Transport Proteins - genetics | Enzyme Induction - drug effects | Thiocyanates - pharmacology | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Cell Death - drug effects | Extracellular Signal-Regulated MAP Kinases - physiology | Isothiocyanates | Sulfides - pharmacology | Caco-2 Cells | G2 Phase - physiology | Protein-Serine-Threonine Kinases - physiology | Enzyme Inhibitors - pharmacology | Cell Division - drug effects | Cell Division - physiology | Proto-Oncogene Proteins c-akt | NAD(P)H Dehydrogenase (Quinone) - biosynthesis | Transcription, Genetic - physiology | MAP Kinase Signaling System - drug effects | Cell Death - physiology | Proto-Oncogene Proteins - physiology | MAP Kinase Kinase Kinases - physiology | Phosphatidylinositol 3-Kinases - physiology | Enzyme Induction - physiology | Glucuronosyltransferase - biosynthesis | Multidrug Resistance-Associated Proteins - metabolism | Index Medicus
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2. Full Text Signaling pathways regulating FSH- and amphiregulin-induced meiotic resumption and cumulus cell expansion in the pig
by Prochazka, R and Blaha, M and Nemcova, L
Reproduction (Cambridge, England), ISSN 1470-1626, 11/2012, Volume 144, Issue 5, pp. 535 - 546
Life Sciences & Biomedicine | Developmental Biology | Reproductive Biology | Science & Technology | Meiosis - physiology | Sus scrofa - physiology | Mitogen-Activated Protein Kinase 14 - antagonists & inhibitors | Gene Expression Regulation - physiology | Amphiregulin | Glycoproteins - pharmacology | Follicle Stimulating Hormone - pharmacology | Glucuronosyltransferase - genetics | Cyclic AMP-Dependent Protein Kinases - physiology | Meiosis - drug effects | Animals | Oocytes - physiology | Signal Transduction - drug effects | Cyclooxygenase 2 - genetics | Intercellular Signaling Peptides and Proteins - pharmacology | Oocytes - drug effects | Female | Mitogen-Activated Protein Kinase 14 - physiology | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Receptor, Epidermal Growth Factor - physiology | Cumulus Cells - physiology | Index Medicus
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3. Full Text Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
by Lijiang Ma and Mei-Fang Lu and Robert J. Schwartz and James F. Martin
Development (Cambridge), ISSN 0950-1991, 12/2005, Volume 132, Issue 24, pp. 5601 - 5611
Cardiac morphogenesis | Epithelial-mesenchymal transition | Bone morphogenetic protein | Mouse | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Bone Morphogenetic Proteins - physiology | Heart - embryology | Heart - physiology | Homeodomain Proteins - metabolism | DNA-Binding Proteins - metabolism | Morphogenesis | Epithelium - embryology | Body Patterning | Hyaluronan Synthases | Bone Morphogenetic Proteins - genetics | Endocardium - physiology | Signal Transduction | Bone Morphogenetic Protein 2 | Endocardium - embryology | Transforming Growth Factor beta - physiology | Nuclear Proteins - metabolism | Bone Morphogenetic Protein Receptors, Type I - metabolism | Animals | Transforming Growth Factor beta - genetics | Glucuronosyltransferase - metabolism | Mesoderm - physiology | Epithelium - physiology | Mice | MSX1 Transcription Factor - metabolism | Mutation | Twist-Related Protein 1 - metabolism | Index Medicus
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4. Full Text Regulation and roles of the hyaluronan system in mammalian reproduction
by Fouladi-Nashta, Ali A and Raheem, Kabir A and Marei, Waleed F and Ghafari, Fataneh and Hartshorne, Geraldine M
Reproduction (Cambridge, England), ISSN 1470-1626, 02/2017, Volume 153, Issue 2, pp. R43 - R58
Review | Life Sciences & Biomedicine | Developmental Biology | Reproductive Biology | Science & Technology | Embryo Implantation - physiology | Hyaluronoglucosaminidase - metabolism | Oocytes - metabolism | Embryonic Development - physiology | Reproduction - physiology | Hyaluronan Receptors - physiology | Hyaluronic Acid - physiology | Reproductive Techniques, Assisted | Pregnancy | Animals | Glucuronosyltransferase - metabolism | Mammals - physiology | Female | Hyaluronan Synthases | Index Medicus
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5. Full Text Biology, physiology and gene expression of grasshopper Oedaleus asiaticus exposed to diet stress from plant secondary compounds
by Huang, Xunbing and Ma, Jingchuan and Qin, Xinghu and Tu, Xiongbing and Cao, Guangchun and Wang, Guangjun and Nong, Xiangqun and Zhang, Zehua
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 8655 - 9
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phytochemicals - chemistry | Gene Expression | Animals | Plants, Edible - chemistry | Quantitative Trait, Heritable | Stress, Physiological | Biomarkers | Animal Feed | Grasshoppers - physiology | Cytochrome | Enzymes | Food plants | UDP-glucuronosyltransferase | Starch | Cytochrome P450 | Detoxification | Gene expression | Lipase | Carboxylesterase | Feeding | Chymotrypsin | Secondary metabolites | Metabolites | Glutathione transferase | Nutrient content | Host plants | Herbivores | Food | Glucuronosyltransferase | Index Medicus
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6. Full Text Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts
by Midgley, Adam C and Rogers, Mathew and Hallett, Maurice B and Clayton, Aled and Bowen, Timothy and Phillips, Aled O and Steadman, Robert
The Journal of biological chemistry, ISSN 0021-9258, 05/2013, Volume 288, Issue 21, pp. 14824 - 14838
Membrane Microdomains - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | ErbB Receptors - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - genetics | Myofibroblasts - metabolism | Glucuronosyltransferase - genetics | Hyaluronan Receptors - metabolism | Hyaluronan Synthases | Cell Differentiation - physiology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | ErbB Receptors - metabolism | Hyaluronic Acid - genetics | Smad Proteins - genetics | Transforming Growth Factor beta1 - genetics | Hyaluronan Receptors - genetics | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - genetics | Myofibroblasts - cytology | Glucuronosyltransferase - metabolism | Hyaluronic Acid - metabolism | Signal Transduction - physiology | Wound Healing - physiology | Enzyme Activation - physiology | Smad Proteins - metabolism | Cell Line, Transformed | Membrane Microdomains - genetics | Index Medicus | Lipid Raft | Glycobiology and Extracellular Matrices | Hyaluronate | Epidermal Growth Factor Receptor (EGFR) | Myofibroblast | CD44
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7. Full Text Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor
by Köhle, Christoph and Bock, Karl Walter
Biochemical pharmacology, ISSN 0006-2952, 2009, Volume 77, Issue 4, pp. 689 - 699
Drug metabolism | Ah receptor | UDP-glucuronosyltransferases | Cytochrome P450s | Conjugate transporters | Pregnane X receptor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Transcription Factors - physiology | Metabolic Detoxication, Phase II | Receptors, Steroid - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Substrate Specificity | Receptors, Cytoplasmic and Nuclear - physiology | Xenobiotics - toxicity | Xenobiotics - pharmacokinetics | Receptor Cross-Talk - physiology | Receptors, Aryl Hydrocarbon - physiology | Transcription Factors - metabolism | Pharmaceutical Preparations - metabolism | Carrier Proteins - metabolism | Drug Interactions | Receptors, Steroid - physiology | Metabolic Detoxication, Phase I | Receptors, Aryl Hydrocarbon - metabolism | Cytochrome P-450 Enzyme System - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Enzymes | Drug resistance in microorganisms | Polypeptides | Corticosteroids | Hydrocarbons | Chemicals | Omeprazole | Antioxidants | Phenobarbital | Polycyclic aromatic hydrocarbons | Carrier proteins | Physiological aspects | Rifampin | Telomerase | Phenytoin | Index Medicus
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8. Full Text The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR
by Sugatani, Junko and Kojima, Hiroyuki and Ueda, Akiko and Kakizaki, Satoru and Yoshinari, Kouichi and Gong, Qi-Hui and Owens, Ida S and Negishi, Masahiko and Sueyoshi, Tatsuya
Hepatology (Baltimore, Md.), ISSN 0270-9139, 05/2001, Volume 33, Issue 5, pp. 1232 - 1238
Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Vertebrates: digestive system | Liver. Bile. Biliary tracts | Phenobarbital - pharmacology | Base Sequence - genetics | Transcription Factors - physiology | Glucuronosyltransferase - drug effects | Humans | Cells, Cultured | Gene Expression Regulation - physiology | Molecular Sequence Data | Receptors, Cytoplasmic and Nuclear - physiology | DNA - genetics | Glucuronosyltransferase - genetics | Transfection | DNA - physiology | Gene Deletion | Enhancer Elements, Genetic - physiology | Mutation | Response Elements - physiology | DNA - drug effects | Index Medicus
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9. Full Text Regulation of MDR1 Expression and Drug Resistance by a Positive Feedback Loop Involving Hyaluronan, Phosphoinositide 3-Kinase, and ErbB2
by Suniti Misra and Shibnath Ghatak and Bryan P. Toole
The Journal of biological chemistry, ISSN 0021-9258, 05/2005, Volume 280, Issue 21, pp. 20310 - 20315
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Phosphorylation | Hyaluronan Receptors - pharmacology | Humans | Hyaluronic Acid - pharmacology | Breast Neoplasms | Hyaluronan Receptors - physiology | Doxorubicin | Hyaluronic Acid - physiology | Glucuronosyltransferase - genetics | Receptor, ErbB-2 - physiology | Chondroitin Sulfate Proteoglycans - pharmacology | Transfection | Hyaluronic Acid - biosynthesis | Nerve Tissue Proteins - pharmacology | Hyaluronan Synthases | Tumor Cells, Cultured | Protein-Serine-Threonine Kinases - physiology | Lectins, C-Type | RNA, Small Interfering - pharmacology | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Hyaluronan Receptors - genetics | Proto-Oncogene Proteins c-akt | Drug Resistance, Neoplasm - genetics | Feedback, Physiological | Brevican | Proto-Oncogene Proteins - physiology | Phosphatidylinositol 3-Kinases - physiology | Genes, MDR - genetics | Index Medicus
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