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Journal Article
Psychopharmacology, ISSN 0033-3158, 06/2017, Volume 234, Issue 11, pp. 1671 - 1681
Rationale Metabotropic glutamate 2 and 3 (mGluR2/3) receptors are implicated in drug addiction as they limit excessive glutamate release during relapse.... 
2-PMPA | Synthetic cathinone | MDPV | Reward | Glutamate | NAAG | SPRAGUE-DAWLEY RATS | LOCOMOTOR STIMULANT | PSYCHIATRY | CONDITIONED PLACE PREFERENCE | BEHAVIORAL SENSITIZATION | PRINCIPAL CONSTITUENT | CONSTITUENT 3,4-METHYLENEDIOXYPYROVALERONE MDPV | PSYCHOACTIVE BATH SALTS | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | INTRACRANIAL SELF-STIMULATION | METHYLENEDIOXYPYROVALERONE MDPV | PHARMACOLOGY & PHARMACY | Glutamate Carboxypeptidase II - antagonists & inhibitors | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Dipeptides - pharmacology | Pyrrolidines - administration & dosage | Rats | Receptors, Metabotropic Glutamate - physiology | Male | Excitatory Amino Acid Antagonists - pharmacology | Benzodioxoles - administration & dosage | Glutamate Carboxypeptidase II - biosynthesis | Rats, Sprague-Dawley | Amino Acids - pharmacology | Dose-Response Relationship, Drug | Animals | Organophosphorus Compounds - pharmacology | Alkaloids - administration & dosage | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Xanthenes - pharmacology | Physiological aspects | Research | Health aspects | Rattus | Drug abuse | Drug addiction | Cortex (prefrontal) | Narcotics | Withdrawal | Circuits | Hyperactivity | Intranasal administration | Carboxypeptidase | Signal transduction | Receptors | Inhibitors | Rodents | Reinforcement | Attenuation | Cocaine | Glutamate carboxypeptidase | Glutamic acid receptors (metabotropic) | N-Acetylaspartylglutamic acid | reward | synthetic cathinone | glutamate
Journal Article
Journal Article
The FEBS Journal, ISSN 1742-464X, 09/2016, Volume 283, Issue 18, pp. 3438 - 3456
Experimental autoimmune encephalomyelitis (EAE) is an inflammatory disease in the murine central nervous system (CNS) and recapitulates the clinical and... 
glutamate excitotoxicity | metabotropic glutamate receptors | 2‐phosphonomethyl pentanedioic acid | experimental autoimmune encephalomyelitis (EAE) | glutamate carboxypeptidase II | Glutamate carboxypeptidase II | Metabotropic glutamate receptors | 2-phosphonomethyl pentanedioic acid | Experimental autoimmune encephalomyelitis (EAE) | Glutamate excitotoxicity | NERVOUS-SYSTEM | NAAG PEPTIDASE INHIBITORS | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-ACETYLASPARTYLGLUTAMATE | DAMAGE | MULTIPLE-SCLEROSIS | T-CELL-ACTIVATION | IN-VIVO | RAT-BRAIN | RECEPTORS | Immunohistochemistry | Spinal Cord - drug effects | Glutamate Carboxypeptidase II - antagonists & inhibitors | Humans | Rats, Inbred Lew | Encephalomyelitis, Autoimmune, Experimental - immunology | Receptors, Metabotropic Glutamate - metabolism | Astrocytes - enzymology | Th1 Cells - immunology | Amino Acids - pharmacology | Protease Inhibitors - pharmacology | Glutamate Carboxypeptidase II - metabolism | Organophosphorus Compounds - pharmacology | Female | Xanthenes - pharmacology | Astrocytes - drug effects | Th1 Cells - drug effects | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Mice, Inbred C57BL | Spinal Cord - enzymology | Excitatory Amino Acid Antagonists - pharmacology | Disease Progression | Spinal Cord - immunology | Animals | Encephalomyelitis, Autoimmune, Experimental - enzymology | Glutamic Acid - metabolism | Mice | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Nervous system diseases | Multiple sclerosis | Immune response | Encephalomyelitis | Development and progression | Amino acids | Glutamate | Encephalitis | Neurotransmitters | Toxicity | Rodents
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2014, Volume 9, Issue 9, p. e102936
Pyridoxine is used as a supplement for treating conditions such as vitamin deficiency as well as neurological disorders such as depression, epilepsy and... 
PAIN MODEL | PERIPHERAL NERVOUS-SYSTEM | MULTIDISCIPLINARY SCIENCES | NEURONS | ISCHEMIC BRAIN-INJURY | GROWTH-FACTOR | SENSORY NEUROPATHY | DIABETIC-NEUROPATHY | NAALADASE INHIBITION | N-ACETYLASPARTYLGLUTAMATE NAAG | THIOL-BASED INHIBITORS | Neuroprotective Agents - therapeutic use | Peripheral Nervous System Diseases - chemically induced | Glutamate Carboxypeptidase II - antagonists & inhibitors | Sulfhydryl Compounds - pharmacology | Neurodegenerative Diseases - prevention & control | Motor Activity - drug effects | Rats | Peripheral Nervous System Diseases - physiopathology | Rats, Sprague-Dawley | Protease Inhibitors - pharmacology | Sensation - drug effects | Glutarates - therapeutic use | Pyridoxine - adverse effects | Animals | Neurodegenerative Diseases - chemically induced | Neuroprotective Agents - pharmacology | Behavior, Animal - drug effects | Female | Sulfhydryl Compounds - therapeutic use | Glutarates - pharmacology | Protease Inhibitors - therapeutic use | Peripheral Nervous System Diseases - drug therapy | Amino acids | Chemotherapy | Glutamate | Cancer | Conduction | Spinal cord | Neurosciences | Epilepsy | Body weight | Nervous system | Diabetic neuropathy | Carboxypeptidase | Parameter sensitivity | Mental depression | Peripheral neuropathy | Nerve conduction | Neurotoxicity | Lumbar region | Pain | Dorsal root ganglia | Neurodegeneration | Rodents | Sensory neurons | Inhibition | Glutamate carboxypeptidase | Growth factors | Drug dosages | EMG | Nutrient deficiency | Diabetes mellitus | Vitamin deficiency | Pyridoxine | Bioavailability | Reaction time task | Ganglia | Latency | Neurological diseases | Medicine | Autism | Reaction time | Diabetes
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2014, Volume 450, Issue 1, pp. 372 - 377
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2012, Volume 343, Issue 3, pp. 746 - 754
Peripheral neuropathy from nerve trauma is a significant problem in the human population and often constitutes a dose-limiting toxicity in patients receiving... 
NAAG PEPTIDASE INHIBITORS | PAIN | AMINO-ACIDS | ACETYL-ASPARTYL-GLUTAMATE | PHARMACOLOGY & PHARMACY | DIABETIC-NEUROPATHY | LINKED ACIDIC DIPEPTIDASE | N-ACETYLASPARTYLGLUTAMATE | NAALADASE INHIBITION | THIOL-BASED INHIBITORS | TEMPORAL-LOBE | Sulfhydryl Compounds - administration & dosage | Benzoates - therapeutic use | Glutamate Carboxypeptidase II - antagonists & inhibitors | Benzoates - chemistry | Male | Antineoplastic Agents - therapeutic use | Organoplatinum Compounds - pharmacology | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Tissue Distribution | Drug Interactions | Enzyme Inhibitors - pharmacokinetics | Enzyme Inhibitors - chemistry | Female | Mice, Inbred DBA | Sulfhydryl Compounds - chemistry | Antineoplastic Agents - pharmacology | Molecular Structure | Neural Conduction - drug effects | Neuralgia - physiopathology | Sciatic Neuropathy - drug therapy | Disease Models, Animal | Cell Survival - drug effects | Leukemia L1210 - drug therapy | Administration, Oral | Rats | Neuralgia - enzymology | Enzyme Inhibitors - therapeutic use | Rats, Sprague-Dawley | Sciatic Neuropathy - enzymology | Sulfhydryl Compounds - pharmacokinetics | Neuralgia - drug therapy | Benzoates - administration & dosage | Hyperalgesia - physiopathology | Animals | Hyperalgesia - drug therapy | Cell Line, Tumor | Sciatic Neuropathy - physiopathology | Mice | Mice, Inbred BALB C | Sulfhydryl Compounds - therapeutic use | Hyperalgesia - enzymology | Organoplatinum Compounds - therapeutic use | Benzoates - pharmacokinetics | Index Medicus
Journal Article