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Advanced Drug Delivery Reviews, ISSN 0169-409X, 06/2013, Volume 65, Issue 6, pp. 782 - 799
Among 12 billion injections administered annually, unsafe delivery leads to > 20 million infections and > 100 million reactions. In an emerging new concept,... 
Molecular farming | Infectious diseases | Bioencapsulation | Hemophilia | Oral vaccines | Autoantigens | Diabetes | Lyophilization | TOXIN-B-SUBUNIT | APICAL MEMBRANE ANTIGEN-1 | HEAT-LABILE ENTEROTOXIN | ESCHERICHIA-COLI | MEROZOITE SURFACE PROTEIN-1 | YERSINIA-PESTIS | TRANSGENIC CHLOROPLASTS | FUSION PROTEIN | PHARMACOLOGY & PHARMACY | NASAL DRUG-DELIVERY | CHOLERA-TOXIN | Factor IX - administration & dosage | Proteins - pharmacokinetics | Administration, Oral | Humans | Vaccines - pharmacokinetics | Freeze Drying | Autoantigens - administration & dosage | Biological Availability | Blood Glucose | Plant Cells | Exenatide | Gastrointestinal Tract - metabolism | Peptides - administration & dosage | Drug Carriers | Plague Vaccine - administration & dosage | Diabetes Mellitus - prevention & control | Malaria Vaccines - administration & dosage | Diabetes Mellitus - therapy | Proteins - administration & dosage | Venoms - administration & dosage | Cholera Vaccines - administration & dosage | Proinsulin - administration & dosage | Vaccines - administration & dosage | Autoimmunity | Glucagon | Dendritic cells | Blood sugar | Biological products industry | Vaccines | Glutamate | Prothrombin complex concentrate | Biopharmaceutics | Proteins | Prevention | Glucose metabolism | Type 1 diabetes | Gastrointestinal system | Cholera toxin | Health aspects | Acids | hemophilia | lyophilization | molecular farming | infectious diseases | bioencapsulation | oral vaccines | diabetes
Journal Article
The Oncologist, ISSN 1083-7159, 01/2008, Volume 13, Issue 1, pp. 5 - 13
Systemic therapy improves the survival and quality of life of patients with advanced stage non‐small cell lung cancer (NSCLC). Several new therapeutic options... 
Systemic therapy | Advanced disease | Maintenance | NSCLC | CARBOPLATIN | advanced disease | systemic therapy | RANDOMIZED CLINICAL-TRIALS | STAGE-IIIB | GEMCITABINE | PHASE-III TRIAL | WEEKLY PACLITAXEL | SUPPORTIVE CARE | VINORELBINE PLUS CISPLATIN | SOUTHWEST-ONCOLOGY-GROUP | ONCOLOGY | COMPARING CISPLATIN | maintenance | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Guanine - analogs & derivatives | Lung Neoplasms - mortality | Humans | Lung Neoplasms - pathology | Platinum - administration & dosage | Antimetabolites, Antineoplastic - administration & dosage | Bevacizumab | Antibodies, Monoclonal, Humanized | Angiogenesis Inhibitors - administration & dosage | Quinazolines - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Deoxycytidine - administration & dosage | Survival Rate | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Pemetrexed | Protein Kinase Inhibitors - administration & dosage | Taxoids - administration & dosage | Antibodies, Monoclonal - administration & dosage | Glutamates - administration & dosage | Quality of Life | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Deoxycytidine - analogs & derivatives | Guanine - administration & dosage | Index Medicus
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 09/2009, Volume 27, Issue 9, pp. 839 - 846
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 02/2013, Volume 83, Issue 2, pp. 174 - 183
This work describes the effect of polymeric microcarriers on the intra- nasal uptake of azolmitriptan for brain targeting. Moreover, the suitability of... 
Nasal administration | Microspheres | Brain targeting | Chitosan | Zolmitriptan | In vivo studies | MUCOADHESIVE MICROSPHERES | DELIVERY-SYSTEMS | CHITOSAN-GLUTAMATE | CEREBROSPINAL-FLUID | RAT MODEL | NASAL ABSORPTION | PHARMACOLOGY & PHARMACY | BIOADHESIVE FORMULATIONS | SUBMICRON EMULSION | HEALTHY-VOLUNTEERS | Polymers - administration & dosage | Chemistry, Pharmaceutical - methods | Hypromellose Derivatives - chemistry | Area Under Curve | Drug Carriers - administration & dosage | Oxazolidinones - administration & dosage | Drug Carriers - chemistry | Adhesives - chemistry | Oxazolidinones - chemistry | Adhesives - administration & dosage | Administration, Intranasal - methods | Swine | Nasal Mucosa - drug effects | Powders - administration & dosage | Tryptamines - chemistry | Chitosan - administration & dosage | Hypromellose Derivatives - administration & dosage | Permeability | Migraine Disorders - drug therapy | Brain - drug effects | Powders - chemistry | Glutamic Acid - administration & dosage | Animals | Chitosan - chemistry | Administration, Intravenous - methods | Glutamic Acid - chemistry | Tryptamines - administration & dosage | Glutamate | Annan hälsovetenskap | Health Science | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Other Health Sciences | Hälsovetenskaper | Health Sciences
Journal Article
Addiction, ISSN 0965-2140, 01/2010, Volume 105, Issue 1, pp. 121 - 133
Background  `Recreational' use of ketamine is spreading rapidly among young people. In healthy individuals an acute dose of the N-methyl D-aspartate (NMDA)... 
cognition | learning and memory | ketamine | recreational use | Chronic use | NMDA receptor antagonist | dependence | depression | longitudinal | glutamate | addiction and substance abuse | Learning and memory | Recreational use | Ketamine | Longitudinal | Dependence | Depression | Cognition | Addiction and substance abuse | Glutamate | FREQUENT | DRUG-USE | INFREQUENT | PSYCHIATRY | SCHIZOPHRENIA | SUBSTANCE ABUSE | EXPERIENCES | K-HOLE | ECSTASY USERS | RECREATIONAL USERS | HEALTHY-VOLUNTEERS | WORKING-MEMORY | Memory - drug effects | Delusions - epidemiology | Follow-Up Studies | Cognition Disorders - chemically induced | Humans | Male | Memory Disorders - diagnosis | Educational Status | Statistics as Topic | Dissociative Disorders - epidemiology | Dose-Response Relationship, Drug | Dissociative Disorders - chemically induced | Ketamine - adverse effects | Psychiatric Status Rating Scales | Time Factors | Substance-Related Disorders - epidemiology | Adult | Female | Depressive Disorder - chemically induced | Depressive Disorder - epidemiology | Excitatory Amino Acid Antagonists - adverse effects | Self Medication - psychology | Cognition Disorders - psychology | Memory Disorders - epidemiology | Self Medication - statistics & numerical data | Excitatory Amino Acid Antagonists - pharmacology | Delusions - chemically induced | Neuropsychological Tests | Recognition (Psychology) - drug effects | Speech Disorders - chemically induced | Speech Disorders - epidemiology | Substance-Related Disorders - psychology | Ketamine - pharmacology | Cognition Disorders - epidemiology | Memory Disorders - chemically induced | Illegal drugs | Methyl aspartate | Substance abuse | Depression, Mental | Drug abuse | Mental depression | Cognitive ability | Mental health
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2010, Volume 30, Issue 23, pp. 7984 - 7992
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 8, pp. 990 - 998
Summary Background Optimum management strategies for patients with advanced non-small-cell lung cancer (NSCLC) with acquired resistance to EGFR tyrosine-kinase... 
Hematology, Oncology and Palliative Medicine | TYROSINE KINASE INHIBITORS | MULTICENTER | ONCOLOGY | ADENOCARCINOMA | ACQUIRED-RESISTANCE | OPEN-LABEL | AFATINIB | ERLOTINIB | GEMCITABINE | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Prospective Studies | Guanine - analogs & derivatives | Lung Neoplasms - mortality | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Lung Neoplasms - pathology | Male | Cisplatin - administration & dosage | Receptor, Epidermal Growth Factor - metabolism | Time Factors | Adult | Female | Quinazolines - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Genetic Predisposition to Disease | Lung Neoplasms - enzymology | Drug Administration Schedule | Administration, Oral | Carcinoma, Non-Small-Cell Lung - genetics | Europe | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Pemetrexed | Disease Progression | Disease-Free Survival | Protein Kinase Inhibitors - administration & dosage | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Asia | Glutamates - administration & dosage | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Aged | Biomarkers, Tumor - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Infusions, Intravenous | Mutation | Guanine - administration & dosage | Medical colleges | Chemotherapy | Strategic planning (Business) | Genetic aspects | Product development | Lung cancer, Non-small cell | Gefitinib | Cancer
Journal Article