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Oncogene, ISSN 0950-9232, 10/2014, Volume 33, Issue 42, pp. 5039 - 5046
Journal Article
Cell, ISSN 0092-8674, 09/2018, Volume 175, Issue 1, pp. 101 - 116.e25
Journal Article
Cell Reports, ISSN 2211-1247, 01/2017, Volume 18, Issue 4, pp. 991 - 1004
Journal Article
Oncogene, ISSN 0950-9232, 01/2014, Volume 33, Issue 5, pp. 556 - 566
Retinoblastoma (Rb) protein is a tumor suppressor that is dysregulated in a majority of human cancers. Rb functions to inhibit cell cycle progression in part... 
Metabolism | Cancer | Glutamine | Retinoblastoma Protein | Tumor Suppressor | retinoblastoma protein | APOPTOSIS | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | G CONTROL | tumor suppressor | CELL-PROLIFERATION | FACTOR-I | glutamine | CELL BIOLOGY | GLYCOLYSIS | INHIBITION | ONCOLOGY | GENETICS & HEREDITY | metabolism | cancer | GROWTH-FACTOR | ENERGY-METABOLISM | Cell Proliferation | Reactive Oxygen Species - metabolism | Glutamate-Cysteine Ligase - biosynthesis | Minor Histocompatibility Antigens | Glutamine - metabolism | Retinoblastoma-Like Protein p107 - genetics | Adenosine Triphosphate - biosynthesis | Oxygen - metabolism | Glutathione - biosynthesis | RNA Interference | Retinoblastoma-Like Protein p130 - metabolism | Fibroblasts | Biological Transport - genetics | Amino Acid Transport System ASC - genetics | Ketoglutaric Acids - metabolism | Glutaminase - biosynthesis | Promoter Regions, Genetic | Retinoblastoma-Like Protein p107 - metabolism | Retinoblastoma Protein - metabolism | Cells, Cultured | Amino Acid Transport System ASC - metabolism | Glutaminase - metabolism | Mice, Knockout | Animals | E2F3 Transcription Factor - biosynthesis | Cell Cycle | Retinoblastoma Protein - genetics | E2F3 Transcription Factor - metabolism | Mice | RNA, Small Interfering | Retinoblastoma-Like Protein p130 - genetics | Amino Acid Transport System ASC - biosynthesis | Glutaminase - genetics | Oncology, Experimental | Physiological aspects | Genetic research | Tumor suppressor genes | Genetic aspects | Research | Studies | Oncology | Tumors
Journal Article
Structure, ISSN 0969-2126, 06/2017, Volume 25, Issue 6, pp. 912 - 923.e5
CAD, the multifunctional protein initiating and controlling de novo biosynthesis of pyrimidines in animals, self-assembles into ∼1.5 MDa hexamers. The... 
X-ray crystallography | carbamoyl phosphate synthetase | multi-angle light scattering | aspartate transcarbamoylase | Chaetomium thermophilum | glutaminase | URA2 | nucleotide metabolism | single-particle electron microscopy | dihydroorotase | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | ASPARTATE TRANSCARBAMOYLASE DOMAIN | FUNCTIONAL-CHARACTERIZATION | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | ORGANIZATION | BIOPHYSICS | YEAST URA2 GENE | DIHYDROOROTASE DOMAIN | PURIFICATION | RAY DIFFRACTION ANALYSIS | CARBAMOYL-PHOSPHATE SYNTHETASE | Carbamyl Phosphate - metabolism | Aspartate Carbamoyltransferase - genetics | Mutagenesis, Site-Directed | Dihydroorotase - genetics | Aspartate Carbamoyltransferase - metabolism | Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - metabolism | Humans | Protein Multimerization | Carbamyl Phosphate - chemistry | Models, Molecular | Chaetomium - enzymology | Crystallography, X-Ray | Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - genetics | Pyrimidines - biosynthesis | Microscopy, Electron | Aspartate Carbamoyltransferase - chemistry | Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) - chemistry | Protein Domains | Dihydroorotase - chemistry | Dihydroorotase - metabolism | Pyrimidines | Analysis | Genomics | Crystals | Physiological aspects | Aspartate | Biosynthesis | Electron microscopy | Structure | Phosphates | Ligases
Journal Article
Journal Article
Redox Biology, ISSN 2213-2317, 06/2019, Volume 24, p. 101218
HSP60 is a major mitochondrial chaperone for maintaining mitochondrial proteostasis. Our previous studies showed that HSP60 was significantly downregulated in... 
HSP60 | ccRCC | Metabolic reprogramming | Glutamine metabolism | METABOLOMICS | GLUTAMINASE C | METABOLISM | MYC | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPRESSION
Journal Article
Journal Article
Journal Article