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Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7381, pp. 380 - 384
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and protein acetylation. In the conventional view of mammalian cell... 
FLUX ANALYSIS | DISTRIBUTIONS | FATTY-ACID SYNTHESIS | MULTIDISCIPLINARY SCIENCES | GROWTH | HYDROXYLATION | CELL-PROLIFERATION | SUPPRESSION | HIF-ALPHA | CANCER | DEHYDROGENASE | CD8-Positive T-Lymphocytes - cytology | Palmitic Acid - metabolism | Isocitrate Dehydrogenase - deficiency | Humans | Glutamine - metabolism | Kidney Neoplasms - metabolism | Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism | Oxygen - metabolism | Cell Hypoxia | Basic Helix-Loop-Helix Transcription Factors - metabolism | Acetyl Coenzyme A - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Ketoglutaric Acids - metabolism | Lipogenesis | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Carbon - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Oxidation-Reduction | Carcinoma, Renal Cell - pathology | Cells, Cultured | Isocitrate Dehydrogenase - genetics | Acetyl Coenzyme A - metabolism | Citric Acid Cycle | Carcinoma, Renal Cell - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Kidney Neoplasms - pathology | Physiological aspects | Hypoxia | Research | Lipid metabolism | Electron transport | Proteins | Confidence intervals | Metabolites | Lipids | Biosynthesis | Glucose | Experiments | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7598, pp. 255 - 258
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7484, pp. 564 - 568
Journal Article
Cell Metabolism, ISSN 1550-4131, 06/2012, Volume 15, Issue 6, pp. 827 - 837
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2012, Volume 109, Issue 23, pp. 8983 - 8988
In addition to glycolysis, the oncogenic transcription factor c-MYC (MYC) stimulates glutamine catabolism to fuel growth and proliferation of cancer cells... 
T lymphocytes | Cell growth | Energy metabolism | Cellular metabolism | Small interfering RNA | Catabolism | Biosynthesis | Tumors | Cancer | Apoptosis | Amino acids | miRNA | Reactive oxygen species | Metabolic tumor suppressor | Redox signaling | APOPTOSIS | MULTIDISCIPLINARY SCIENCES | amino acids | CELL-GROWTH | HYPOXIA | CANCER | B-CELLS | PYRROLINE-5-CARBOXYLIC ACID | redox signaling | OXIDASE | GENE | reactive oxygen species | TUMOR-SUPPRESSOR | CARBOXYLATION | metabolic tumor suppressor | Gas Chromatography-Mass Spectrometry | Reactive Oxygen Species - metabolism | Nitrogen Isotopes - metabolism | Oxidation-Reduction | Proline - metabolism | Pyrroline Carboxylate Reductases - metabolism | Humans | Glutamine - metabolism | MicroRNAs - metabolism | Carbon Isotopes - metabolism | Gene Expression Regulation, Enzymologic - physiology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Chromatin Immunoprecipitation | Gene Expression Regulation, Enzymologic - genetics | Cell Line, Tumor | Nuclear Magnetic Resonance, Biomolecular | Proline Oxidase - metabolism | Real-Time Polymerase Chain Reaction | Cell proliferation | Transcription factors | Proline | Cell metabolism | Genetic aspects | Properties | Glutamine | Metabolism | Prostate cancer | Index Medicus | Biological Sciences
Journal Article
Glia, ISSN 0894-1491, 11/2016, Volume 64, Issue 11, pp. 1841 - 1856
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2014, Volume 111, Issue 3, pp. 960 - 965
Journal Article
Gastroenterology, ISSN 0016-5085, 04/2018, Volume 154, Issue 5, pp. 1465 - 1479.e13
Cirrhosis results from accumulation of myofibroblasts derived from quiescent hepatic stellate cells (Q-HSCs); it regresses when myofibroblastic HSCs are... 
Metabolic Reprogramming | Liver Diseases | Hippo Pathway | Fibrogenesis | FIBROSIS | TRANSCRIPTIONAL ACTIVITY | PULMONARY-HYPERTENSION | FATTY LIVER-DISEASE | MECHANISMS | CANCER | METABOLISM | GLUCOSE | GROWTH | Fibro-genesis | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Liver - pathology | Cell Proliferation | Mitochondria, Liver - metabolism | Humans | Glutamine - metabolism | Hedgehog Proteins - metabolism | Hepatic Stellate Cells - metabolism | Smoothened Receptor - metabolism | Phosphoproteins - metabolism | Smoothened Receptor - genetics | Case-Control Studies | Cellular Reprogramming | Myofibroblasts - metabolism | Transfection | Hedgehog Proteins - genetics | RNA Interference | Time Factors | Liver Cirrhosis - metabolism | Liver Cirrhosis, Experimental - pathology | Cell Transdifferentiation | Ketoglutaric Acids - metabolism | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | Myofibroblasts - pathology | Mitochondria, Liver - pathology | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Cells, Cultured | Gene Expression Regulation | Rats | Glutaminase - metabolism | Liver Cirrhosis, Experimental - genetics | Phosphoproteins - genetics | Mice, Knockout | Phenotype | Animals | Energy Metabolism | Adaptor Proteins, Signal Transducing - genetics | Liver Cirrhosis - pathology | Adaptor Proteins, Signal Transducing - metabolism | Liver Cirrhosis, Experimental - metabolism | Glucose metabolism | Metabolites | RNA | Analysis | Liver | Physiological aspects | Genetic research | Verteporfin | Development and progression | Mice | Liver cirrhosis | Glutamine | Index Medicus | Abridged Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 2011, Volume 35, Issue 6, pp. 871 - 882
Journal Article