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Journal of Vascular Surgery, ISSN 0741-5214, 2008, Volume 47, Issue 2, pp. 422 - 431
Journal Article
Journal of Heart and Lung Transplantation, ISSN 1053-2498, 2014, Volume 33, Issue 9, pp. 963 - 970
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2001, Volume 276, Issue 50, pp. 47107 - 47115
Treatment with the DNA topoisomerase inhibitors etoposide, doxorubicin, and camptothecin, and with the alkylating agents cisplatin and melphalan, caused... 
OXYGEN | SUPEROXIDE ANION | BUTHIONINE SULFOXIMINE | INHIBITION | U937 CELLS | NEURONAL DEATH | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIAL-FUNCTION | SENSITIVITY | HYDROGEN-PEROXIDE | STRESS | Buthionine Sulfoximine - pharmacology | Nucleic Acid Synthesis Inhibitors - pharmacology | Reactive Oxygen Species | Glutathione - metabolism | Alkylating Agents - pharmacology | Humans | Topoisomerase I Inhibitors | Antineoplastic Agents, Alkylating - pharmacology | Immunoblotting | Monocytes - metabolism | Oxygen - metabolism | Antineoplastic Agents - toxicity | Necrosis | Dose-Response Relationship, Drug | Flow Cytometry | Time Factors | U937 Cells | Adenosine Triphosphate - metabolism | Cell Death | Radiation-Protective Agents - pharmacology | Antimetabolites, Antineoplastic - pharmacology | Antineoplastic Agents - pharmacology | Melphalan - pharmacology | Membrane Potentials - drug effects | Enzyme Inhibitors - pharmacology | Hydrogen Peroxide - pharmacology | Etoposide - pharmacology | Spectrometry, Fluorescence | Glutathione - antagonists & inhibitors | Mitochondria - metabolism | Antioxidants - pharmacology | Cisplatin - pharmacology | Hypoxia | Antineoplastic Agents, Phytogenic - pharmacology | Camptothecin - pharmacology | Dose-Response Relationship, Radiation | Doxorubicin - pharmacology | Apoptosis | butylated hydroxyanisole | melphelan | N-Acetyl-L-cysteine | cisplatin | Index Medicus
Journal Article
Transplantation Proceedings, ISSN 0041-1345, 2013, Volume 45, Issue 6, pp. 2486 - 2490
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 470 - 479
Bacterial endotoxin lipopolysaccharide (LPS) is responsible for the multiorgan dysfunction that characterizes septic shock and is causal in the myocardial... 
Green fluorescent protein- Microtubule-associated protein light chain 3 | Lipopolysaccharide | Oxidative stress | Hl-1 cardiac myocyte | TRANSCRIPTIONAL ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | HL-1 cardiac myocyte | CARDIAC MYOCYTES | NECROSIS-FACTOR-ALPHA | MYOCARDIAL DEPRESSION | PROGRAMMED CELL-DEATH | ENDOTOXEMIC RATS | SCAVENGER RECEPTOR | green fluorescent protein-microtubule-associated protein light chain 3 | SEPTIC SHOCK | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | lipopolysaccharide | NF-KAPPA-B | oxidative stress | Tumor Necrosis Factor-alpha - metabolism | Mitochondria, Heart - metabolism | Glutathione - metabolism | Mitochondria, Heart - pathology | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Autophagy - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Cytoprotection | Animals, Newborn | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Sirolimus - pharmacology | Hydrogen Peroxide - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Signal transduction | Bacteria | Oxidation | Biochemistry | Cytokines | Sugar | Index Medicus
Journal Article
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2009, Volume 296, Issue 6, pp. 1318 - 1323
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e59281 - e59281
Platelets play an important role in thrombosis and in neo-vascularisation as they release and produce factors that both promote and suppress angiogenesis.... 
ACTIVATION | ALPHA-GRANULES | PROSTACYCLIN | MULTIDISCIPLINARY SCIENCES | NITRIC-OXIDE | GROWTH-FACTOR | ANGIOGENESIS INHIBITOR | PROTEINS | PLASMINOGEN | CARCINOMA | ENDOSTATIN | Endothelium, Vascular - cytology | Humans | Culture Media, Conditioned - pharmacology | Endothelium, Vascular - drug effects | Valerates - pharmacology | Cell Hypoxia | S-Nitrosoglutathione - pharmacology | Platelet Aggregation Inhibitors - pharmacology | Epoprostenol - pharmacology | Collagen - pharmacology | Platelet Aggregation - drug effects | Aspirin - pharmacology | Blood Platelets - drug effects | Vascular Endothelial Growth Factor A - pharmacology | Cell Line | Adenine - analogs & derivatives | Angiogenesis Inhibitors - pharmacology | Adenine - pharmacology | Peptides - pharmacology | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Cell Movement - drug effects | Blood Platelets - metabolism | Endothelial Cells - cytology | Angiostatins - pharmacology | Endothelial Cells - drug effects | Aspirin | Collagen | Hostages | Comparative analysis | Vascular endothelial growth factor | Thrombosis | Blood clot | Endothelium | Prostacyclin | Acetylsalicylic acid | Cell adhesion & migration | Vascularization | Proteins | Angiogenesis | Cell growth | Blood platelets | Thromboembolism | Pharmaceutical sciences | Glutathione | Gold | Immunoglobulins | Research & development--R&D | Pharmacology | Platelet aggregation | Electron microscopy | Organelles | Endothelial cells | Blood clots | Inhibitors | Acids | Microscopy | Granular materials | Nitric oxide | Pharmacy | Hypoxia | Granules | Kinetics | Angiostatin | Immunofluorescence | Platelets | Cell migration | Cancer | Index Medicus | Research & development | R&D
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 01/2010, Volume 38, Issue 1, pp. 92 - 99
The aim of the current study is to identify the human cytochrome P450 (P450) isoforms involved in the two oxidative steps in the bioactivation of clopidogrel... 
MECHANISM-BASED INHIBITION | ANTIAGGREGATING ACTIVITY | POLYMORPHISMS | TICLOPIDINE | PHARMACOKINETICS | HEALTHY-SUBJECTS | PHARMACOLOGY & PHARMACY | PRASUGREL | PHARMACODYNAMICS | MONOCLONAL-ANTIBODIES | ATORVASTATIN | Microsomes - metabolism | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Cytochrome P-450 Enzyme System - metabolism | Sulfaphenazole - pharmacology | Microsomes - drug effects | Cytochrome P-450 CYP3A - genetics | Cytochrome P-450 CYP1A2 - genetics | Antibodies - immunology | Omeprazole - pharmacology | Microsomes, Liver - enzymology | Platelet Aggregation Inhibitors - pharmacokinetics | Ticlopidine - pharmacokinetics | Oxidoreductases, N-Demethylating - metabolism | Aryl Hydrocarbon Hydroxylases - immunology | Oxidation-Reduction | Enzyme Inhibitors - pharmacology | Ticlopidine - analogs & derivatives | Oxidoreductases, N-Demethylating - immunology | Cytochrome P-450 CYP3A - metabolism | Cell Line, Tumor | Cytochrome P-450 Enzyme System - genetics | Theophylline - pharmacology | Kinetics | Cytochrome P-450 CYP2C9 | Theophylline - analogs & derivatives | Oxidoreductases, N-Demethylating - genetics | Glutathione - metabolism | Ketoconazole - pharmacology | Biotransformation - physiology | Cytochrome P-450 CYP1A2 Inhibitors | Microsomes, Liver - drug effects | Ticlopidine - metabolism | NADP - metabolism | Platelet Aggregation Inhibitors - metabolism | Cytochrome P-450 CYP3A - immunology | Cell Line | Aryl Hydrocarbon Hydroxylases - antagonists & inhibitors | Cytochrome P-450 CYP1A2 - immunology | Biocatalysis | Mephenytoin - analogs & derivatives | Cytochrome P-450 CYP1A2 - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Mephenytoin - pharmacology | Antibodies - pharmacology | Cytochrome P-450 CYP3A Inhibitors | Cytochrome P-450 CYP2C19 | Clopidogrel | Cytochrome P-450 CYP2B6 | Index Medicus
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2014, Volume 67, pp. 366 - 376
Chronic lead exposure induces hypertension affecting endothelial function. We investigated whether low-concentration lead exposure alters blood pressure and... 
Hypertension | Rat aorta | Lead acetate | Free radicals | Vasoconstrictor prostanoids | ROS | Local renin–angiotensin system | Local renin-angiotensin system | SYSTEM | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | BLOOD-PRESSURE | GUANYLATE-CYCLASE | INDUCED HYPERTENSION | SMOOTH-MUSCLE | NITRIC-OXIDE METABOLISM | ENDOTHELIUM | CYCLOOXYGENASE PATHWAYS | ENDOCRINOLOGY & METABOLISM | CARDIOVASCULAR-DISEASE | Rats, Wistar | Prostaglandins - pharmacology | Male | Aorta - metabolism | Lead Poisoning - metabolism | Phenylephrine - pharmacology | Acetophenones - pharmacology | Vascular Resistance - drug effects | Blood Pressure - drug effects | Aorta - physiopathology | Lead Poisoning - physiopathology | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Superoxide Dismutase - pharmacology | Vasodilator Agents - pharmacology | Cyclooxygenase 2 Inhibitors - pharmacology | Aorta - drug effects | Losartan - pharmacology | Rats | Antioxidants - pharmacology | Vasoconstriction - drug effects | Indomethacin - pharmacology | Animals | Renin-Angiotensin System - drug effects | Vasodilation - drug effects | Nitric Oxide - metabolism | Chronic Disease | COX-2 inhibitors | Prostaglandins | International agencies | Angiotensin | Dosage and administration | Superoxide | Blood pressure | Indomethacin | Index Medicus
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 03/2006, Volume 6, Issue 3, pp. 496 - 504
Journal Article