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Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7664, pp. 453 - 457
Plasticity of the cell state has been proposed to drive resistance to multiple classes of cancer therapies, thereby limiting their effectiveness(1-4). A... 
EPITHELIAL-MESENCHYMAL TRANSITION | METABOLISM | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | HUMAN-MELANOMA CELLS | SENSITIVITY | DEATH | INHIBITOR | EXPRESSION | SIGNATURE | REVEALS | Prostatic Neoplasms - metabolism | Cadherins - metabolism | Humans | Mesoderm - drug effects | Melanoma - enzymology | Male | Lipid Peroxides - metabolism | Zinc Finger E-box-Binding Homeobox 1 - genetics | Neoplasms - genetics | Mesoderm - enzymology | Cell Death | Epithelial-Mesenchymal Transition | Lipid Peroxidation - drug effects | Cell Transdifferentiation | Prostatic Neoplasms - drug therapy | Melanoma - metabolism | Glutathione Peroxidase - metabolism | Prostatic Neoplasms - pathology | Reproducibility of Results | Neoplasms - enzymology | Melanoma - pathology | Iron - metabolism | Neoplasms - drug therapy | Cell Lineage | Drug Resistance, Neoplasm - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Proteomics | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Mesoderm - metabolism | Neoplasms - pathology | Mesoderm - pathology | Peroxidase | Research | Chemical properties | Chemical synthesis | Analysis | Cancer cells | Therapy | Biotechnology | Carcinoma | Mesenchyme | Genes | Lipid peroxidation | Lipids | Iron | Genomes | Phospholipids | Kinases | Cancer therapies | Proteins | Organoids | Dissipation | Peroxides | Lipid metabolism | Glutathione | Transfer RNA | Peroxidation | Glutathione peroxidase | Enzymes | Mortality | Melanoma | Selenocysteine | Tumor cell lines | Metabolism | Substrates | Cell death | Lipoxygenase | Prostate cancer | Prostate | Tumors | Apoptosis | Cancer | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 2009, Volume 10, Issue 4, pp. 260 - 272
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2008, Volume 8, Issue 3, pp. 237 - 248
Oxidative stress in conjunction with glutathione depletion has been linked with various acute and chronic degenerative disorders, yet the molecular mechanisms... 
HUMDISEASE | SIGNALING | MOUSE DEVELOPMENT | APOPTOSIS-INDUCING FACTOR | PATHWAY | 12-LIPOXYGENASE | EMBRYONIC STEM-CELLS | ENDOCRINOLOGY & METABOLISM | ATHEROSCLEROSIS | MITOCHONDRIAL DYSFUNCTION | 15-LIPOXYGENASE | HYDROPEROXIDE GLUTATHIONE-PEROXIDASE | NUCLEAR FORM | CELL BIOLOGY | Neurons - pathology | Arachidonate 12-Lipoxygenase - metabolism | Humans | Oxidative Stress - physiology | Apoptosis Inducing Factor - antagonists & inhibitors | Fluorenes - pharmacology | Arachidonate 15-Lipoxygenase - deficiency | Neurons - metabolism | Cell Death - drug effects | Glutathione Peroxidase - deficiency | alpha-Tocopherol - pharmacology | Arachidonate 12-Lipoxygenase - deficiency | Apoptosis Inducing Factor - metabolism | Glutathione Peroxidase - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Genotype | Hippocampus - pathology | Arachidonate 15-Lipoxygenase - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Glutathione Peroxidase - genetics | Lipid Peroxidation - physiology | Mice, Knockout | Hippocampus - metabolism | Animals | Cell Death - physiology | Alleles | Mice | Mice, Congenic | Prevention | Oxidative stress | Neurosciences | Thiols | Active oxygen | Cell death | Environmental health | Tocopherols | Development and progression | Biochemistry | Peroxidase
Journal Article