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Journal Article
Life Sciences, ISSN 0024-3205, 11/2017, Volume 188, pp. 1 - 9
The vasorelaxant effects of the anti-diabetic drug, mitiglinide in phenylephrine (Phe)-pre-contracted aortic rings were examined. Arterial tone measurement was... 
Mitiglinide | Voltage-dependent K+ channel | Aortic smooth muscle | SERCA pump | channel | Voltage-dependent K | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | PHYSIOLOGICAL ROLES | ATPASE | ARTERIES | GENES | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | AGENTS | TYPE-2 DIABETES-MELLITUS | EXPRESSION | MODULATION | Potassium Channels, Voltage-Gated - agonists | Endothelium, Vascular - drug effects | Male | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Muscle, Smooth - drug effects | Drug Interactions | Phenylephrine - pharmacology | Glyburide - pharmacology | Oxadiazoles - pharmacology | Aorta, Thoracic - physiology | Indoles - pharmacology | Muscle, Smooth - physiology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - antagonists & inhibitors | Aorta, Thoracic - drug effects | Isoindoles - pharmacology | 4-Aminopyridine - pharmacology | Rabbits | Nifedipine - pharmacology | Adenine - analogs & derivatives | Vasodilator Agents - pharmacology | Vasodilator Agents - antagonists & inhibitors | Adenine - pharmacology | Barium - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - physiology | Pyrroles - pharmacology | Animals | Signal Transduction - drug effects | Thapsigargin - pharmacology | Carbazoles - pharmacology | Isoindoles - antagonists & inhibitors | Protein kinase A | Electric potential | Protein kinase G | Smooth muscle | Activation | Potassium conductance | Guanylate cyclase | Channels | Vasodilation | Ca2+-transporting ATPase | Adenylate cyclase | Thapsigargin | Phenylephrine | Measurement methods | Aorta | Life sciences | Potassium channels (voltage-gated) | Inhibition | Pretreatment | Glibenclamide | Diabetes mellitus | Muscles | Cyclopiazonic acid | Endothelium | Nifedipine | Resistance | Signaling | Conductance | Endoplasmic reticulum | Adenosine triphosphatase | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 11/2015, Volume 767, pp. 52 - 60
Journal Article
Journal Article
Hypertension, ISSN 0194-911X, 09/2004, Volume 44, Issue 3, pp. 271 - 276
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2013, Volume 190, Issue 2, pp. 746 - 756
Journal Article
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 01/2005, Volume 21, Issue 1, pp. 151 - 160
The mechanisms by which uridine triphosphate (UTP) stimulates ATP release from Schwann cells cultured from the sciatic nerve were investigated using online... 
Bioluminescence | Protein kinase C | Purinergic receptors | Exocytosis | purinergic receptors | NERVE | MECHANISMS | RELEASE | ASTROCYTES | NEUROSCIENCES | UTP | NUCLEOTIDE RECEPTORS | bioluminescence | GLUTAMATE | CALCIUM | NEURONS | exocytosis | SMOOTH-MUSCLE-CELLS | protein kinase C | Guanosine Triphosphate - pharmacology | Nucleic Acid Synthesis Inhibitors - pharmacology | Calcium - metabolism | Adenosine Triphosphate - secretion | Brefeldin A - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Receptors, Purinergic P2Y2 | Cytochalasin D - pharmacology | Phenanthridines - pharmacology | Type C Phospholipases - antagonists & inhibitors | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Alkaloids | Botulinum Toxins - pharmacology | Glycyrrhetinic Acid - pharmacology | Drug Interactions | Isoquinolines - pharmacology | Glyburide - pharmacology | Time Factors | Botulinum Toxins, Type A | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Sciatic Nerve - cytology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Protein Synthesis Inhibitors - pharmacology | Pyridoxal Phosphate - analogs & derivatives | Schwann Cells - secretion | Suramin - pharmacology | Schwann Cells - drug effects | Animals, Newborn | Pyridoxal Phosphate - pharmacology | Uridine Triphosphate - pharmacology | Purinergic P2 Receptor Antagonists | Rats | Protein Kinase C - antagonists & inhibitors | Purinergic P2 Receptor Agonists | Sulfonamides - pharmacology | Microscopy, Confocal - methods | Rats, Sprague-Dawley | Immunohistochemistry - methods | Animals | Benzophenanthridines | Receptors, Purinergic P2 - metabolism | Thapsigargin - pharmacology | Furosemide - pharmacology | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2010, Volume 113, Issue 2, pp. 530 - 542
Adenosine produces cardiovascular depressor effects in various brain regions. However, the cellular mechanisms underlying these effects remain unclear. The... 
Adenosine receptors | G proteins | Hypothalamus | K | Sympathetic nervous system | Synaptic transmission | SUPRAOPTIC NUCLEUS | PRESYNAPTIC INHIBITION | SPONTANEOUSLY HYPERTENSIVE-RATS | sympathetic nervous system | SENSITIVE K+ CHANNELS | RECEPTOR AGONISTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD | K-ATP | NEUROSCIENCES | SIGNALING PATHWAY | adenosine receptors | ENDOGENOUS ADENOSINE | synaptic transmission | CENTRAL-NERVOUS-SYSTEM | hypothalamus | SYNAPTIC GABA RELEASE | Analgesics - pharmacology | Tolbutamide - pharmacology | KATP Channels - physiology | Male | Xanthines - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Paraventricular Hypothalamic Nucleus - cytology | Glyburide - pharmacology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Action Potentials - drug effects | Potassium Channel Blockers - pharmacology | Guanosine Diphosphate - pharmacology | Membrane Potentials - drug effects | Triazines - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Adenosine - pharmacology | Bicuculline - pharmacology | Thionucleotides - pharmacology | Membrane Potentials - physiology | Rats, Sprague-Dawley | Receptor, Adenosine A1 - metabolism | GABA Antagonists - pharmacology | Triazoles - pharmacology | Animals | Guanosine Diphosphate - analogs & derivatives | In Vitro Techniques | Cell research | Adenosine | Neurons | Tolbutamide | GABA | Glibenclamide | Cytochemistry | Membrane proteins | Cardiovascular disease | Potassium | Adenosine triphosphatase | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 531, Issue 1, pp. 87 - 95
The possible participation of the nitric oxide (NO)-cyclic GMP-protein kinase G (PKG) pathway on gabapentin-induced spinal antiallodynic activity was assessed... 
Pinacidil | Gabapentin | Nitric oxide | Protein kinase G | Diazoxide | Guanylyl cyclase | K + channel opener | Neuropathic pain | channel opener | SENSITIVE POTASSIUM CHANNELS | nitric oxide | TACTILE ALLODYNIA | K+ channel opener | RANDOMIZED CONTROLLED-TRIAL | NERVE INJURY | VASCULAR SMOOTH-MUSCLE | guanylyl cyclase | neuropathic pain | gabapentin | diazoxide | pinacidil | RABBIT VENTRICULAR MYOCYTES | PHARMACOLOGY & PHARMACY | protein kinase G | UP-REGULATION | CALCIUM-CHANNEL | PERIPHERAL ANTINOCICEPTIVE ACTION | Analgesics - pharmacology | Okadaic Acid - pharmacology | Potassium Channels - physiology | Pinacidil - administration & dosage | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Glyburide - pharmacology | Time Factors | Charybdotoxin - pharmacology | Oxadiazoles - pharmacology | Potassium Channel Blockers - pharmacology | Spinal Nerves - injuries | Spinal Nerves - physiopathology | Enzyme Inhibitors - pharmacology | Cyclohexanecarboxylic Acids - administration & dosage | Rats | gamma-Aminobutyric Acid - pharmacology | Indazoles - pharmacology | NG-Nitroarginine Methyl Ester - chemistry | Cyclic GMP - metabolism | Signal Transduction - drug effects | Pain - physiopathology | Nitric Oxide Synthase - metabolism | Carbazoles - pharmacology | Amines - pharmacology | Diazoxide - administration & dosage | Cyclic GMP - antagonists & inhibitors | Diazoxide - pharmacology | Rats, Wistar | Stereoisomerism | Nitric Oxide Synthase - antagonists & inhibitors | gamma-Aminobutyric Acid - administration & dosage | Apamin - pharmacology | Cyclic GMP-Dependent Protein Kinases - metabolism | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | Amines - administration & dosage | Female | Indoles - pharmacology | Injections, Spinal | NG-Nitroarginine Methyl Ester - pharmacology | Pinacidil - pharmacology | Vasodilator Agents - pharmacology | Pain - prevention & control | Nitric Oxide - antagonists & inhibitors | Analgesics - administration & dosage | Animals | Cyclohexanecarboxylic Acids - pharmacology | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Nitric Oxide - metabolism | Vasodilator Agents - administration & dosage | Index Medicus
Journal Article
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2011, Volume 37, Issue 3, pp. 353 - 357
Journal Article