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1. Full Text Management of adverse events associated with ixazomib plus lenalidomide/dexamethasone in relapsed/refractory multiple myeloma
by Kumar, Shaji and Moreau, Philippe and Hari, Parameswaran and Mateos, Maria Victoria and Ludwig, Heinz and Shustik, Chaim and Masszi, Tamas and Spencer, Anew and Hájek, Roman and Romeril, Kenneth and Avivi, Irit and Liberati, Anna M and Minnema, Monique C and Einsele, Hermann and Lonial, Sagar and Berg, Deborah and Lin, Jianchang and Gupta, Neeraj and Esseltine, Dixie Lee and Richardson, Paul G
British journal of haematology, ISSN 0007-1048, 08/2017, Volume 178, Issue 4, pp. 571 - 582
toxicity | multiple myeloma | proteasome inhibitor | Hematology | dosing | ixazomib | Life Sciences & Biomedicine | Science & Technology | Glycine - analogs & derivatives | Peripheral Nervous System Diseases - chemically induced | Follow-Up Studies | Glycine - adverse effects | Nausea - chemically induced | Humans | Middle Aged | Drug Eruptions - therapy | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Dexamethasone - adverse effects | Male | Boron Compounds - administration & dosage | Dose-Response Relationship, Drug | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Nausea - therapy | Aged, 80 and over | Adult | Leukocyte Count | Glycine - administration & dosage | Thalidomide - adverse effects | Drug Eruptions - etiology | Hematologic Diseases - chemically induced | Dexamethasone - administration & dosage | Double-Blind Method | Drug Administration Schedule | Administration, Oral | Peripheral Nervous System Diseases - therapy | Thalidomide - administration & dosage | Hematologic Diseases - therapy | Vomiting - chemically induced | Platelet Count | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Boron Compounds - adverse effects | Aged | Vomiting - therapy | Complications and side effects | Corticosteroids | Analysis | Multiple myeloma | Nausea | Backache | Lithium compounds | Thrombocytopenia | Edema | Back pain | Dexamethasone | Toxicity | Exanthema | Feasibility studies | Diarrhea | Peripheral neuropathy | Patients | Bleeding | Side effects | Pain | Vomiting | Constipation | Tourmaline | Index Medicus | Haematological Malignancy | Research Paper
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2. Full Text Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma
by Moreau, Philippe and Masszi, Tamás and Grzasko, Norbert and Bahlis, Nizar J and Hansson, Markus and Pour, Ludek and Sandhu, Irwindeep and Ganly, Peter and Baker, Bartrum W and Jackson, Sharon R and Stoppa, Anne-Marie and Simpson, David R and Gimsing, Peter and Palumbo, Antonio and Garderet, Laurent and Cavo, Michele and Kumar, Shaji and Touzeau, Cyrille and Buadi, Francis K and Laubach, Jacob P and Berg, Deborah T and Lin, Jianchang and Di Bacco, Alessandra and Hui, Ai-Min and van de Velde, Helgi and Richardson, Paul G and TOURMALINE-MM1 Study Grp and TOURMALINE-MM1 Study Group
The New England journal of medicine, ISSN 0028-4793, 04/2016, Volume 374, Issue 17, pp. 1621 - 1634
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Glycine - analogs & derivatives | Glycine - adverse effects | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Boron Compounds - administration & dosage | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Exanthema - chemically induced | Aged, 80 and over | Adult | Glycine - administration & dosage | Dexamethasone - administration & dosage | Double-Blind Method | Administration, Oral | Kaplan-Meier Estimate | Proportional Hazards Models | Thrombocytopenia - chemically induced | Thalidomide - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Quality of Life | Boron Compounds - adverse effects | Aged | Care and treatment | Dosage and administration | Dexamethasone | Multiple myeloma | Thrombocytopenia | Inhibitor drugs | Drug therapy | Peripheral neuropathy | Survival | Patients | Drug dosages | Proteasome inhibitors | Quality of life | Index Medicus | Abridged Index Medicus | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
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3. Full Text Improved outcomes of octogenarians and nonagenarians with acute myeloid leukemia in the era of novel therapies
by Jeng, Mark Y and Dutta, Ritika and Tan, Irena T and Zhang, Tian Y and Mannis, Gabriel N
American journal of hematology, ISSN 0361-8609, 11/2020, Volume 95, Issue 11, pp. E305 - E308
Life Sciences & Biomedicine | Hematology | Science & Technology | Glycine - analogs & derivatives | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Pyridines - administration & dosage | Pyrimidines - administration & dosage | Humans | Pyrazines - administration & dosage | Male | Survival Rate | Bridged Bicyclo Compounds, Heterocyclic - administration & dosage | Leukemia, Myeloid, Acute - mortality | Disease-Free Survival | Antibodies, Monoclonal, Humanized - administration & dosage | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Female | Retrospective Studies | Aniline Compounds - administration & dosage | Cyclopentanes - administration & dosage | Glycine - administration & dosage | Sulfonamides - administration & dosage | Myeloid leukemia | Acute myeloid leukemia | Index Medicus
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4. Full Text Ixazomib-based frontline therapy in patients with newly diagnosed multiple myeloma in real-life practice showed comparable efficacy and safety profile with those reported in clinical trial: a multi-center study
by Li, Jing and Bao, Li and Xia, Zhongjun and Wang, Sili and Zhou, Xin and Ding, Kaiyang and Zhang, Wenhao and Yang, Wei and Li, Bingzong and Fu, Chengcheng and Chen, Bing and Hua, Luoming and Wang, Liang and Luo, Jun and Yang, Yang and Xu, Tianhong and Wang, Weida and Huang, Yun and Wu, Guolin and Liu, Peng
Annals of hematology, ISSN 0939-5555, 11/2020, Volume 99, Issue 11, pp. 2589 - 2598
Myeloma | Ixazomib | Frontline | Real-world | Life Sciences & Biomedicine | Hematology | Science & Technology | Peripheral Nervous System Diseases - diagnosis | Glycine - analogs & derivatives | Cyclophosphamide - administration & dosage | Peripheral Nervous System Diseases - chemically induced | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Glycine - adverse effects | Multiple Myeloma - mortality | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Dexamethasone - adverse effects | Male | Peripheral Nervous System Diseases - physiopathology | Boron Compounds - administration & dosage | Cyclophosphamide - adverse effects | Multiple Myeloma - drug therapy | Adult | Female | Glycine - administration & dosage | Doxorubicin - administration & dosage | Thalidomide - adverse effects | Dexamethasone - administration & dosage | Drug Administration Schedule | Treatment Outcome | Thalidomide - administration & dosage | Remission Induction | Lenalidomide - administration & dosage | Multiple Myeloma - pathology | Antibodies, Monoclonal - administration & dosage | Adolescent | Survival Analysis | Lenalidomide - adverse effects | Boron Compounds - adverse effects | Aged | Neoplasm Staging | Doxorubicin - adverse effects | Index Medicus
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5. Full Text Effects of oral administration of tripeptides derived from type I collagen (collagen tripeptide) on atherosclerosis development in hypercholesterolemic rabbits
by Tang, Lihua and Sakai, Yasuo and Ueda, Yoshimichi and Katsuda, Shogo
Journal of bioscience and bioengineering, ISSN 1389-1723, 05/2015, Volume 119, Issue 5, pp. 558 - 563
Collagen tripeptide | Kurosawa and Kusanagi-hypercholesterolemic rabbit | Smooth muscle cells | Total cholesterol | Atherosclerosis | Plaque | Food Science & Technology | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Cholesterol - blood | Collagen Type I - chemistry | Male | Myocytes, Smooth Muscle - drug effects | Plaque, Atherosclerotic - pathology | Myocytes, Smooth Muscle - cytology | Disease Models, Animal | DNA Damage - drug effects | Plaque, Atherosclerotic - complications | Rabbits | Atherosclerosis - pathology | Atherosclerosis - drug therapy | Administration, Oral | Plaque, Atherosclerotic - prevention & control | Atherosclerosis - complications | Macrophages - cytology | Aorta - pathology | Animals | Collagen Type I - administration & dosage | Hypercholesterolemia - complications | Macrophages - drug effects | Collagen Type I - pharmacology | Collagen Type I - therapeutic use | Oxidative Stress - drug effects | Plaque, Atherosclerotic - drug therapy | Proliferating Cell Nuclear Antigen - metabolism | Atherosclerosis - prevention & control | Hypercholesterolemia | Proteases | Collagen | Analysis | Low density lipoproteins | Glycine | Index Medicus
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6. Full Text Ghrelin receptor (GHS‐R1A) antagonism suppresses both operant alcohol self‐administration and high alcohol consumption in rats
by Landgren, Sara and Simms, Jeffrey A and Hyytiä, Petri and Engel, Jörgen A and Bartlett, Selena E and Jerlhag, Elisabet and Sahlgrenska akademin and Institute of Neuroscience and Physiology, Department of Pharmacology and Göteborgs universitet and Institutionen för neurovetenskap och fysiologi, sektionen för farmakologi and Gothenburg University and Sahlgrenska Academy
Addiction biology, ISSN 1355-6215, 01/2012, Volume 17, Issue 1, pp. 86 - 94
alcohol | ethanol | AA rats | operant self‐administration | ghrelin receptors | motivation | operant self-administration | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Substance Abuse | Science & Technology | Glycine - analogs & derivatives | Choice Behavior - drug effects | Alcoholism | Rats, Long-Evans | Ethanol - administration & dosage | Rats | Receptors, Ghrelin - antagonists & inhibitors | Male | Alcohol Drinking | Triazoles - pharmacology | Animals | Analysis of Variance | Conditioning, Operant - drug effects | Glycine - pharmacology | Signal Transduction - drug effects | Central Nervous System Depressants - administration & dosage | Self Administration - statistics & numerical data | Disease Models, Animal | Care and treatment | Substance abuse | Drinking of alcoholic beverages | Genes | Operant conditioning | Ethanol | Circuits | Mesolimbic system | Body weight | Homeostasis | Antagonists | Single-nucleotide polymorphism | Hypothalamus | Drug development | Drug self-administration | ghrelin | Addiction | Alcoholic beverages | Reinforcement | Drug dependence | Index Medicus | Physiology | Fysiologi | AA rats; alcohol; ethanol; ghrelin receptors; motivation; operant self-administration
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7. Full Text Generation of bioactive prolyl‐hydroxyproline (Pro‐Hyp) by oral administration of collagen hydrolysate and degradation of endogenous collagen
by Sato, Kenji and Jimi, Shiro and Kusubata, Masashi
International journal of food science & technology, ISSN 0950-5423, 06/2019, Volume 54, Issue 6, pp. 1976 - 1980
peptide | wound healing | fibroblast | Collagen | food | Pro‐Hyp | Life Sciences & Biomedicine | Food Science & Technology | Science & Technology | Granulation | Peptides | Hydroxyproline | Oral administration | Organs | Collagens | Glycine | Dermatitis | Blood | Biological activity | Ingestion | Blood plasma | Degradation | Animal tissues | Fibroblasts | Skin
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8. Full Text Protein association of the neurotoxin and non-protein amino acid BMAA (β-N-methylamino-l-alanine) in the liver and brain following neonatal administration in rats
by Karlsson, Oskar and Jiang, Liying and Andersson, Marie and Ilag, Leopold L and Brittebo, Eva B
Toxicology letters, ISSN 0378-4274, 04/2014, Volume 226, Issue 1, pp. 1 - 5
Autoradiography | N-(2-aminoethyl) glycine | ALS/PDC | Mass spectrometry | Misincorporation | Cyanobacteria | Life Sciences & Biomedicine | Toxicology | Science & Technology | Animals, Newborn | Brain - diagnostic imaging | Protein Biosynthesis | Excitatory Amino Acid Agonists - metabolism | Liver - metabolism | Rats | Male | Chromatography, High Pressure Liquid | Blood-Brain Barrier - metabolism | Brain - metabolism | Excitatory Amino Acid Agonists - administration & dosage | Radiography | Tissue Distribution | Tandem Mass Spectrometry | Amino Acids, Diamino - administration & dosage | Animals | Time Factors | Injections, Subcutaneous | Liver - diagnostic imaging | Protein Binding | Neurotoxins - metabolism | Neurotoxins - administration & dosage | Amino Acids, Diamino - metabolism | Protein biosynthesis | Amino acids | Index Medicus
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9. Full Text Co-administration of methyl donors along with guanidinoacetic acid reduces the incidence of hyperhomocysteinaemia compared with guanidinoacetic acid administration alone
by Ostojic, Sergej M and Niess, Barbara and Stojanovic, Marko and Obrenovic, Milos
British journal of nutrition, ISSN 0007-1145, 09/2013, Volume 110, Issue 5, pp. 865 - 870
Full Papers | Human and Clinical Nutrition | Clinical enzymes | Homocysteine | Betaine | Folic acid | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Glycine - analogs & derivatives | Double-Blind Method | Humans | Male | Betaine - pharmacology | Vitamin B Complex - pharmacology | Hyperhomocysteinemia - drug therapy | Vitamin B Complex - administration & dosage | Young Adult | Betaine - administration & dosage | Glycine - pharmacology | Hyperhomocysteinemia - prevention & control | Adult | Female | Glycine - administration & dosage | Nutrition | Food additives | Index Medicus
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