Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (7967) 7967
Publication (924) 924
Book Review (63) 63
Newsletter (46) 46
Book Chapter (31) 31
Book / eBook (7) 7
Conference Proceeding (7) 7
Dissertation (5) 5
Magazine Article (4) 4
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (5335) 5335
glycine (2885) 2885
index medicus (2794) 2794
rats (2711) 2711
male (2490) 2490
glycine - pharmacology (2255) 2255
humans (2115) 2115
neurosciences (1947) 1947
pharmacology & pharmacy (1861) 1861
glycine - analogs & derivatives (1597) 1597
mice (1299) 1299
female (1017) 1017
biochemistry & molecular biology (974) 974
glycine - metabolism (948) 948
rats, sprague-dawley (935) 935
dose-response relationship, drug (926) 926
in vitro techniques (834) 834
glutamate (757) 757
rats, wistar (734) 734
strychnine - pharmacology (667) 667
excitatory amino acid antagonists - pharmacology (649) 649
analysis (641) 641
neurons - drug effects (619) 619
glycine agents - pharmacology (599) 599
neurons (531) 531
cells, cultured (509) 509
gaba (491) 491
physiology (491) 491
amino acids (471) 471
time factors (458) 458
chemistry, medicinal (446) 446
brain (440) 440
nmda receptor (440) 440
glycine - chemistry (432) 432
article (421) 421
patch-clamp techniques (416) 416
kinetics (407) 407
rat (405) 405
expression (377) 377
in-vitro (377) 377
research (377) 377
receptors, n-methyl-d-aspartate - antagonists & inhibitors (368) 368
proteins (363) 363
receptors, n-methyl-d-aspartate - metabolism (362) 362
peptides (358) 358
physiological aspects (353) 353
membrane potentials - drug effects (345) 345
neurons - physiology (341) 341
schizophrenia (341) 341
pharmacology (332) 332
gaba antagonists - pharmacology (331) 331
synaptic transmission - drug effects (325) 325
neuroprotective agents - pharmacology (321) 321
structure-activity relationship (319) 319
inhibition (315) 315
cell biology (313) 313
disease models, animal (313) 313
cells (301) 301
electrophysiology (300) 300
bicuculline - pharmacology (297) 297
activation (294) 294
excitatory amino acid agonists - pharmacology (288) 288
psychiatry (285) 285
research article (285) 285
neurons - metabolism (281) 281
rat-brain (274) 274
toxicology (274) 274
amino acid sequence (273) 273
adult (272) 272
gamma-aminobutyric acid - metabolism (264) 264
metabolism (264) 264
anti-bacterial agents - pharmacology (263) 263
receptors (260) 260
enzymes (259) 259
gamma-aminobutyric acid - pharmacology (256) 256
receptors, n-methyl-d-aspartate - drug effects (254) 254
biochemistry, general (252) 252
enzyme inhibitors - pharmacology (252) 252
hippocampus - drug effects (251) 251
cell line (250) 250
cancer (249) 249
ligands (247) 247
brain - metabolism (246) 246
calcium - metabolism (246) 246
nmda (246) 246
life sciences (244) 244
glycine receptor (243) 243
animals, newborn (242) 242
cell line, tumor (242) 242
antineoplastic agents - pharmacology (241) 241
in-vivo (241) 241
molecular sequence data (240) 240
rodents (240) 240
biomedicine (238) 238
mice, inbred c57bl (237) 237
neurology (237) 237
binding sites (235) 235
receptors, glycine - metabolism (235) 235
glycine receptors (234) 234
oxidative stress (234) 234
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (7892) 7892
Japanese (75) 75
Russian (50) 50
German (29) 29
Italian (23) 23
French (21) 21
Chinese (18) 18
Ukrainian (4) 4
Polish (2) 2
Spanish (2) 2
Czech (1) 1
Hungarian (1) 1
Slovak (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent
by Jost, Marco and Chen, Yuwen and Gilbert, Luke A and Horlbeck, Max A and Krenning, Lenno and Menchon, Grégory and Rai, Ankit and Cho, Min Y and Stern, Jacob J and Prota, Andrea E and Kampmann, Martin and Akhmanova, Anna and Steinmetz, Michel O and Tanenbaum, Marvin E and Weissman, Jonathan S
Molecular Cell, ISSN 1097-2765, 10/2017, Volume 68, Issue 1, pp. 210 - 223.e6
Chemical libraries paired with phenotypic screens can now readily identify compounds with therapeutic potential. A central limitation to exploiting these... 
CRISPRi | chemical genetics | genome-wide CRISPR screening | rigosertib | microtubules | CRISPRa | drug target identification | drug mechanism of action | Myelodysplastic Syndromes | Genetic Testing | Vinblastine | Tubulin Modulators | Humans | Gene Expression Regulation, Neoplastic | Antineoplastic Agents | Drug Resistance, Neoplasm | Glycine | Lentivirus | Recombinant Fusion Proteins | Journal Article | Tubulin | Small Molecule Libraries | Microtubules | CRISPR-Cas Systems | K562 Cells | RNA, Guide | Colchicine | HeLa Cells | Mutation | Genetic Vectors | Kinesin | Sulfones | PROTEIN | COLCHICINE | SMALL MOLECULES | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENOMIC ASSAYS | TARGETS | RISK MYELODYSPLASTIC SYNDROMES | TUBULIN | INHIBITOR | BINDING AGENTS | CELL BIOLOGY | Colchicine - pharmacology | Glycine - analogs & derivatives | Small Molecule Libraries - pharmacology | RNA, Guide - genetics | RNA, Guide - metabolism | Tubulin Modulators - pharmacology | Tubulin - genetics | Sulfones - pharmacology | Genetic Testing - methods | Recombinant Fusion Proteins - metabolism | Lentivirus - metabolism | Microtubules - metabolism | Tubulin - metabolism | Glycine - chemistry | Microtubules - drug effects | Sulfones - chemistry | Microtubules - ultrastructure | Kinesin - genetics | Lentivirus - genetics | Antineoplastic Agents - pharmacology | Tubulin - chemistry | Myelodysplastic Syndromes - metabolism | Tubulin Modulators - chemistry | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Antineoplastic Agents - chemistry | Kinesin - metabolism | Glycine - pharmacology | Recombinant Fusion Proteins - genetics | Myelodysplastic Syndromes - genetics | Vinblastine - pharmacology | Myelodysplastic Syndromes - pathology | Tubulins | Genomics | Genetic screening | Biochemical genetics | Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Glycine receptor mechanism elucidated by electron cryo-microscopy
by Du, Juan and Lü, Wei and Wu, Shenping and Cheng, Yifan and Gouaux, Eric
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 224 - 229
The strychnine-sensitive glycine receptor (GlyR) mediates inhibitory synaptic transmission in the spinal cord and brainstem and is linked to neurological... 
RAT SPINAL-CORD | GATED ION-CHANNEL | ANION PERMEATION | MULTIDISCIPLINARY SCIENCES | NICOTINIC ACETYLCHOLINE-RECEPTOR | CYS-LOOP RECEPTORS | EM STRUCTURE DETERMINATION | CRYO-EM | CRYSTAL-STRUCTURES | CHLORIDE CHANNEL | ANTAGONIST-BINDING | Protein Subunits - drug effects | Glycine - metabolism | Allosteric Regulation | Protein Conformation - drug effects | Receptors, Glycine - antagonists & inhibitors | Protein Subunits - metabolism | Ivermectin - metabolism | Strychnine - metabolism | Receptors, Glycine - agonists | Neurotransmitter Agents - pharmacology | Receptors, Glycine - metabolism | Binding Sites | Signal Transduction | Neurotransmitter Agents - metabolism | Models, Molecular | Zebrafish | Receptors, Glycine - ultrastructure | Strychnine - pharmacology | Ivermectin - pharmacology | Rotation | Cryoelectron Microscopy | Animals | Glycine - pharmacology | Protein Subunits - chemistry | Ion Channel Gating - drug effects | Biological research | Glycine receptors | Cryoelectron microscopy | Physiological aspects | Research | Molecular biology | Methods | Biology, Experimental | Signal transduction | Nervous system | Ligands | Neurotransmitters | Microscopy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Endocannabinoids Potentiate Synaptic Transmission through Stimulation of Astrocytes
by Navarrete, Marta and Araque, Alfonso
Neuron, ISSN 0896-6273, 2010, Volume 68, Issue 1, pp. 113 - 126
Endocannabinoids and their receptor CB1 play key roles in brain function. Astrocytes express CB1Rs that are activated by endocannabinoids released by neurons.... 
ENDOGENOUS CANNABINOIDS | ACTIVATION | CA1 PYRAMIDAL CELLS | EXCITATORY SYNAPSES | NEURONS | LONG-TERM POTENTIATION | GLIAL-CELLS | NEUROSCIENCES | MODULATION | HIPPOCAMPAL SYNAPSES | PLASTICITY | Cannabinoid Receptor Modulators - metabolism | Cannabinoid Receptor Modulators - pharmacology | Glycine - analogs & derivatives | Synaptic Transmission - physiology | Synaptic Transmission - genetics | Calcium - metabolism | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Resorcinols - pharmacology | Drug Interactions | Photolysis | Piperidines - pharmacology | Pyramidal Cells - physiology | Egtazic Acid - analogs & derivatives | Synaptic Transmission - drug effects | Pyramidal Cells - drug effects | Electric Stimulation - methods | Endocannabinoids | Excitatory Postsynaptic Potentials - genetics | Pyrazoles - pharmacology | Animals, Newborn | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Chelating Agents - pharmacology | Hippocampus - cytology | Mice, Knockout | Astrocytes - physiology | Animals | Egtazic Acid - pharmacology | Glycine - pharmacology | Cannabinoid Receptor Modulators - antagonists & inhibitors | Benzoates - pharmacology | Thapsigargin - pharmacology | Mice | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - deficiency | In Vitro Techniques | Glutamate | Neurons | Studies | Retina | Transmitters | Potentiation | Brain | Neurotransmitter release | Astrocytes | Glutamic acid receptors | Cannabinoid CB1 receptors | synaptic depression | Calcium signalling | Pyramidal cells | Synaptic transmission | Endogenous stimuli | Receptor mechanisms | Glutamic acid receptors (metabotropic) | Hippocampus | Neurotransmission
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Allele-specific inhibitors inactivate mutant KRAS G12C by a trapping mechanism
by Lito, Piro and Solomon, Martha and Li, Lian-Sheng and Hansen, Rasmus and Rosen, Neal
Virtual Reality, ISSN 1359-4338, 01/2016, Volume 351, Issue 6273, pp. 1 - 9
It is thought that KRAS oncoproteins are constitutively active because their guanosine triphosphatase (GTPase) activity is disabled. Consequently, drugs... 
CELL LUNG-CANCER | BLADDER-CARCINOMA ONCOGENE | ACTIVATION | GENE | STRUCTURAL BASIS | SOS | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | GUANINE-NUCLEOTIDE EXCHANGE | RAS-GTP | PROTEINS | Lung Neoplasms - drug therapy | Adenocarcinoma of Lung | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Protein Conformation - drug effects | Antineoplastic Agents - therapeutic use | Piperazines - chemistry | Azetidines - pharmacology | Molecular Targeted Therapy | Cysteine - genetics | Time Factors | Enzyme Inhibitors - chemistry | Proto-Oncogene Proteins p21(ras) - chemistry | HEK293 Cells | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Guanosine Triphosphate - chemistry | Glycine - genetics | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Adenocarcinoma - enzymology | Enzyme Inhibitors - pharmacology | Piperazines - therapeutic use | Antineoplastic Agents - chemistry | Adenocarcinoma - drug therapy | Azetidines - chemistry | Enzyme Inhibitors - therapeutic use | Piperazines - pharmacology | Azetidines - therapeutic use | Proto-Oncogene Proteins p21(ras) - antagonists & inhibitors | Alleles | Cell Line, Tumor | Mutation | Cytidine Diphosphate - chemistry | Signal transduction | Cell growth | Pharmaceutical sciences | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design
by Schrader, Jil and Henneberg, Fabian and Mata, Ricardo A and Tittmann, Kai and Schneider, Thomas R and Stark, Holger and Bourenkov, Gleb and Chari, Ashwin
Science, ISSN 0036-8075, 08/2016, Volume 353, Issue 6299, pp. 594 - 598
The proteasome is a validated target for anticancer therapy, and proteasome inhibition is employed in the clinic for the treatment of tumors and hematological... 
CARFILZOMIB | CRYSTAL-STRUCTURE | SUBSTRATE | MULTIDISCIPLINARY SCIENCES | APPROVAL | BORTEZOMIB | REVEALS | Boron Compounds - chemistry | Catalytic Domain - drug effects | Boron Compounds - pharmacology | Glycine - analogs & derivatives | Threonine - chemistry | Proteasome Inhibitors - pharmacology | Humans | Proteasome Endopeptidase Complex - chemistry | Proteasome Inhibitors - chemistry | Crystallography, X-Ray | Boronic Acids - chemistry | Bortezomib - pharmacology | Antineoplastic Agents - chemistry | Threonine - analogs & derivatives | Threonine - pharmacology | Glycine - chemistry | Glycine - pharmacology | Proteasome Endopeptidase Complex - ultrastructure | Biocatalysis - drug effects | Bortezomib - chemistry | Drug Design | Protein Conformation | Antineoplastic Agents - pharmacology | Boronic Acids - pharmacology | Proteins | Cell growth | Drug therapy | Proteases | Cancer therapies | Drugs | Therapy | Inhibitors | Medical services | Inhibition | Crystal structure | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons
by Kaufman, Alexandra M and Milnerwood, Austen J and Sepers, Marja D and Coquinco, Ainsley and She, Kevin and Wang, Liang and Lee, Hwan and Craig, Ann Marie and Cynader, Max and Raymond, Lynn A
Journal of Neuroscience, ISSN 0270-6474, 03/2012, Volume 32, Issue 12, pp. 3992 - 4003
The NMDAR plays a unique and vital role in subcellular signaling. Calcium influx initiates signaling cascades important for both synaptic plasticity and... 
IN-VITRO | STATE TRANSITIONS | LONG-TERM POTENTIATION | SUBUNIT COMPOSITION | D-ASPARTATE RECEPTOR | HUNTINGTONS-DISEASE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | DIFFERENTIAL ROLES | CELL-DEATH | NUCLEUS-ACCUMBENS | Microfluidic Analytical Techniques - methods | Electric Stimulation | Rats, Wistar | Embryo, Mammalian | Coculture Techniques | Receptors, N-Methyl-D-Aspartate - metabolism | Neurons - cytology | Cerebral Cortex - cytology | Corpus Striatum - cytology | N-Methylaspartate - pharmacology | CREB-Binding Protein - metabolism | Glycine Agents - pharmacology | Transfection - methods | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Female | Tetrodotoxin - pharmacology | 4-Aminopyridine - pharmacology | Potassium Channel Blockers - pharmacology | GABA-A Receptor Antagonists - pharmacology | Nifedipine - pharmacology | Synapses - physiology | Vesicular Glutamate Transport Protein 1 - metabolism | Cells, Cultured | Rats | Sodium Channel Blockers - pharmacology | Strychnine - pharmacology | Bicuculline - pharmacology | Calcium Channel Blockers - pharmacology | Nerve Tissue Proteins - metabolism | Pregnancy | Patch-Clamp Techniques | Animals | Analysis of Variance | Glutamate Decarboxylase - metabolism | Luminescent Proteins - genetics | Signal Transduction - physiology | Luminescent Proteins - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Design and Synthesis of DiselenoBisBenzamides (DISeBAs) as Nucleocapsid Protein 7 (NCp7) Inhibitors with anti-HIV Activity
by Sancineto, Luca and Mariotti, Alice and Bagnoli, Luana and Marini, Francesca and Desantis, Jenny and Iraci, Nunzio and Santi, Claudio and Pannecouque, Christophe and Tabarrini, Oriana
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2015, Volume 58, Issue 24, pp. 9601 - 9614
The interest in the synthesis of Se-containing compounds is growing with the discovery of derivatives exhibiting various biological activities. In this... 
TARGET | POTENT | CHEMISTRY, MEDICINAL | TAT-MEDIATED TRANSCRIPTION | ANALOGS | COLORIMETRIC ASSAY | RESISTANCE | PATIENT | MUTATIONS | SELENIUM | 6-DESFLUOROQUINOLONES | Anti-HIV Agents - pharmacology | Glycine - analogs & derivatives | Humans | Drug Resistance, Viral | Structure-Activity Relationship | Organoselenium Compounds - chemistry | Organoselenium Compounds - pharmacology | Isoleucine - pharmacology | Isoleucine - chemistry | Glycine - chemistry | HIV-1 - isolation & purification | Benzamides - pharmacology | Benzamides - chemistry | Glutamic Acid - pharmacology | HIV-1 - drug effects | gag Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | Molecular Dynamics Simulation | Anti-HIV Agents - chemistry | Glutamic Acid - analogs & derivatives | Glycine - pharmacology | Isoleucine - analogs & derivatives | Cell Line, Tumor | Molecular Docking Simulation | Simian Immunodeficiency Virus - drug effects | Glutamic Acid - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells
by Chauhan, Dharminder and Tian, Ze and Zhou, Bin and Kuhn, Deborah and Orlowski, Robert and Raje, Noopur and Richardson, Paul and Anderson, Kenneth C
Clinical Cancer Research, ISSN 1078-0432, 08/2011, Volume 17, Issue 16, pp. 5311 - 5321
Purpose: The success of bortezomib therapy for treatment of multiple myeloma (MM) led to the development of structurally and pharmacologically distinct novel... 
THERAPY | CANCER CELLS | ONCOLOGY | INDUCED APOPTOSIS | GROWTH | DRUG-RESISTANCE | BORTEZOMIB | COMBINATION | NF-KAPPA-B | GENETIC ABNORMALITIES | P53 | Glycine - analogs & derivatives | Caspase 9 - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Caspase 8 - metabolism | Biological Availability | NF-kappa B - metabolism | Thalidomide - pharmacology | Thalidomide - analogs & derivatives | Multiple Myeloma - drug therapy | Dexamethasone - pharmacology | Antineoplastic Agents - pharmacology | Glycine - pharmacokinetics | Boron Compounds - pharmacology | Cell Survival - drug effects | Bortezomib | Administration, Oral | Boron Compounds - pharmacokinetics | Enzyme Activation - drug effects | Mice, SCID | Multiple Myeloma - metabolism | Blotting, Western | Drug Synergism | Xenograft Model Antitumor Assays | Multiple Myeloma - pathology | Animals | Glycine - pharmacology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Proteasome Endopeptidase Complex - metabolism | Proteasome Inhibitors | Pyrazines - pharmacology | Boronic Acids - pharmacology | Novel therapeutics | Myeloma | Proteasome inhibitor | Apoptosis | Proteasome
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Inhibition of Glycine Transporter-I as a Novel Mechanism for the Treatment of Depression
by Huang, Chih-Chia and Wei, I-Hua and Huang, Chieh-Liang and Chen, Kuang-Ti and Tsai, Mang-Hung and Tsai, Priscilla and Tun, Rene and Huang, Kuo-Hao and Chang, Yue-Cune and Lane, Hsien-Yuan and Tsai, Guochuan Emil
Biological Psychiatry, ISSN 0006-3223, 2013, Volume 74, Issue 10, pp. 734 - 741
Background Antidepressants, aiming at monoaminergic neurotransmission, exhibit delayed onset of action, limited efficacy, and poor compliance. Glutamatergic... 
Psychiatry | Anxiety | elevated plus maze | N-methyl-D-aspartate | sarcosine | glutamate | forced swimming test | ADD-ON TREATMENT | N-METHYLGLYCINE SARCOSINE | PROFILES | CITALOPRAM | SCHIZOPHRENIA | D-ASPARTATE ANTAGONIST | NEUROSCIENCES | ANTIPSYCHOTICS | D-SERINE | DOUBLE-BLIND | ANTIDEPRESSANT RESPONSE | Sarcosine - administration & dosage | Citalopram - pharmacology | Double-Blind Method | Rats, Wistar | Humans | Rats | Male | Antidepressive Agents, Second-Generation - pharmacology | Antidepressive Agents, Second-Generation - administration & dosage | Antidepressive Agents - therapeutic use | Depression - drug therapy | Sarcosine - therapeutic use | Animals | Citalopram - administration & dosage | Adult | Antidepressive Agents - administration & dosage | Female | Antidepressive Agents - pharmacology | Glycine Plasma Membrane Transport Proteins - antagonists & inhibitors | Sarcosine - pharmacology | Depressive Disorder, Major - drug therapy | Disease Models, Animal | Medical colleges | Amino acids | Drug therapy | Glutamate | Antidepressants | Depression, Mental
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text A Role for Melanopsin in Alpha Retinal Ganglion Cells and Contrast Detection
by Schmidt, Tiffany M and Alam, Nazia M and Chen, Shan and Kofuji, Paulo and Li, Wei and Prusky, Glen T and Hattar, Samer
Neuron, ISSN 0896-6273, 05/2014, Volume 82, Issue 4, pp. 781 - 788
Distinct subclasses of retinal ganglion cells (RGCs) mediate vision and nonimage-forming functions such as circadian photoentrainment. This distinction stems... 
IRRADIANCE | FORM | ADAPTATION | NEURONS | MICE | PROJECTIONS | NEUROSCIENCES | Action Potentials - genetics | Rod Opsins - ultrastructure | Male | Glycine Agents - pharmacology | Rod Opsins - genetics | Retina - cytology | Reaction Time - drug effects | Rod Opsins - metabolism | Excitatory Amino Acid Agents - pharmacology | Female | Rod Opsins - deficiency | Action Potentials - drug effects | Retinal Ganglion Cells - ultrastructure | Retinal Ganglion Cells - classification | Retinal Ganglion Cells - physiology | Contrast Sensitivity - physiology | Mice, Inbred C57BL | Mice, Transgenic | Strychnine - pharmacology | Reaction Time - genetics | GABA Antagonists - pharmacology | Animals | Contrast Sensitivity - genetics | Picrotoxin - pharmacology | Luminescent Proteins - genetics | Mice | In Vitro Techniques | Luminescent Proteins - metabolism | Ganglion | Neurosciences | Retina | Behavior | Rodents | Light
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Targeting glutamate signalling in depression: Progress and prospects
by Murrough, James W and Abdallah, Chadi G and Mathew, Sanjay J
Nature Reviews Drug Discovery, ISSN 1474-1776, 07/2017, Volume 16, Issue 7, pp. 472 - 486
Major depressive disorder (MDD) is severely disabling, and current treatments have limited efficacy. The glutamate N-methyl-D-aspartate receptor (NMDAR)... 
TREATMENT-RESISTANT DEPRESSION | MAGNETIC-RESONANCE-SPECTROSCOPY | RAPID ANTIDEPRESSANT RESPONSE | NMDA RECEPTOR COMPLEX | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PHARMACOLOGY & PHARMACY | RANDOMIZED CONTROLLED-TRIAL | GAMMA-AMINOBUTYRIC-ACID | D-ASPARTATE ANTAGONIST | GLYCINE TRANSPORTER-I | INTRAVENOUS SUBANESTHETIC KETAMINE | SITE PARTIAL AGONIST | Depressive Disorder, Major - physiopathology | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Humans | Drug Design | Antidepressive Agents - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Glutamic Acid - metabolism | Ketamine - pharmacology | Depressive Disorder, Major - drug therapy | Psychological aspects | Dosage and administration | Drug therapy | Antidepressants | Depression, Mental
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Modification of zeolite 4A for use as an adsorbent for glyphosate and as an antibacterial agent for water
by Zavareh, Siamak and Farrokhzad, Zahra and Darvishi, Farshad
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 07/2018, Volume 155, pp. 1 - 8
The aim of this work was to design a low cost adsorbent for efficient and selective removal of glyphosate from water at neutral pH conditions. For this... 
Zeolite 4A | Antibacterial activity | Water pollution | Adsorption | Glyphosate | MECHANISMS | NEUROTOXICITY | AQUEOUS-SOLUTION | HERBICIDE | ENVIRONMENTAL SCIENCES | ACTIVATED CARBON | EFFICIENT REMOVAL | EQUILIBRIUM | DEGRADATION | MONTMORILLONITE | TOXICOLOGY | Glycine - analogs & derivatives | Glycine - chemistry | Disinfectants - pharmacology | Herbicides - chemistry | Zeolites - pharmacology | Water Pollutants, Chemical - chemistry | Anti-Bacterial Agents - pharmacology | Kinetics | Water Purification | Zeolites - chemistry | Hydrogen-Ion Concentration | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights