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The Journal of biological chemistry, ISSN 1083-351X, 09/2009, Volume 284, Issue 36, pp. 24035 - 24048
.... Biglycan, a ubiquitous leucine-rich repeat proteoglycan of the extracellular matrix, interacts with TLR2/4 on macrophages... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Toll-Like Receptor 2 - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Immunity, Innate - genetics | Extracellular Matrix - metabolism | Caspase 1 - metabolism | Male | Ureteral Obstruction - metabolism | Interleukin-1beta - genetics | Inflammation - metabolism | Kidney - metabolism | Carrier Proteins - immunology | Signal Transduction | Proteoglycans - immunology | Extracellular Matrix Proteins - genetics | Proteoglycans - metabolism | Toll-Like Receptor 4 - genetics | Biglycan | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Ureteral Obstruction - immunology | Macrophages - metabolism | Receptors, Purinergic P2 - metabolism | Toll-Like Receptor 2 - immunology | Mice | Proteoglycans - genetics | Extracellular Matrix - immunology | Kidney - immunology | Caspase 1 - immunology | Extracellular Matrix - genetics | Receptors, Purinergic P2 - genetics | Ureteral Obstruction - genetics | Interleukin-1beta - biosynthesis | Lung - metabolism | Receptors, Purinergic P2 - immunology | Extracellular Matrix Proteins - metabolism | Macrophages - immunology | Carrier Proteins - biosynthesis | Interleukin-1beta - immunology | Inflammation - immunology | Protein Structure, Tertiary - genetics | Receptors, Purinergic P2X7 | Carrier Proteins - genetics | Immunity, Innate - immunology | Animals | Caspase 1 - genetics | Extracellular Matrix Proteins - immunology | Receptors, Purinergic P2X4 | Inflammation - genetics | Lung - immunology | Animal models | Reactive oxygen species | Oligomerization | Proteoglycans | Transcription | Lung | Inflammation | Macrophages | Kidney | Stress | Caspase-1 | Purine P2X receptors | Signal transduction | Cell activation | TLR2 protein | Interleukin 1 | Toll-like receptors | Extracellular matrix | Sepsis | Cooperativity | Injuries | Index Medicus | Glycobiology and Extracellular Matrices
Journal Article
PloS one, ISSN 1932-6203, 09/2017, Volume 12, Issue 9, pp. e0185125 - e0185125
Extracellular matrix plays a role in differentiation and phenotype development of its resident cells... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Basement Membrane - ultrastructure | Elasticity | Extracellular Matrix - metabolism | Extracellular Matrix - chemistry | Basement Membrane - chemistry | Sinoatrial Node - chemistry | Microscopy, Electrochemical, Scanning | Heart Ventricles - ultrastructure | Sinoatrial Node - ultrastructure | Swine | Mass Spectrometry | Microscopy, Atomic Force | Fibronectins - ultrastructure | Tensile Strength | Elastin - metabolism | Elastin - ultrastructure | Collagen - ultrastructure | Proteome | Myocytes, Cardiac - chemistry | Basement Membrane - metabolism | Fibronectins - metabolism | Collagen - metabolism | Heart Ventricles - chemistry | Biomechanical Phenomena | Extracellular Matrix - ultrastructure | Animals | Biological Clocks - physiology | Fluorescent Antibody Technique | Proteomics | Myocytes, Cardiac - metabolism | Sinoatrial Node - metabolism | Heart Ventricles - metabolism | Biomechanics | Physiological aspects | Extracellular matrix | Genetic aspects | Research | Elastin | Heart | Deformation | Transplants & implants | Laboratories | Collagens | Genomes | Proteins | Engineering | Biochemical composition | Fibroblasts | Physiology | Matrix protein | Cardiology | Heart diseases | Scanning electron microscopy | Medical research | Internal medicine | Tissue engineering | Mechanical properties | Cardiomyocytes | Abundance | Muscle contraction | Medicine | Properties (attributes) | Collagen | Stem cells | Scientific imaging | Mechanical stimuli | Ventricle | Differentiation | Mass spectrometry | Integrins | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2008, Volume 283, Issue 50, pp. 34796 - 34807
...) to the extracellular matrix protein fibronectin. In contrast to other systems, where heparin acts as a protein scaffold, we found that heparin functions catalytically to modulate VEGF binding site availability on fibronectin... 
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Models, Chemical | Humans | Extracellular Matrix - metabolism | Recombinant Proteins - chemistry | Vascular Endothelial Growth Factor A - chemistry | Animals | Fibronectins - chemistry | Cattle | Anticoagulants - pharmacology | Protein Binding | Catalysis | Kinetics | Binding Sites | Heparin - chemistry | Heparin - pharmacology | Index Medicus | Glycobiology and Extracellular Matrices
Journal Article