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Carbohydrate Research, ISSN 0008-6215, 05/2014, Volume 390, Issue 1, pp. 33 - 41
Hsp90 (Heat shock protein-90) is a chaperone protein and an established anti-apoptotic target in cancer therapy. Most of the known small-molecule inhibitors... 
Hsp90 | Glycodiversification | Phenol glycosylation | O-Benzoxazolyl imidate (OBox) | Eupomatenoid | Phase Transfer Catalysis | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | BIOSYNTHESIS | DYNAMICS | INHIBITORS | BENZOFURANS | CHEMISTRY, APPLIED | Heat shock proteins
Journal Article
Chemical Science, ISSN 2041-6520, 05/2012, Volume 3, Issue 5, pp. 1640 - 1644
Growth of Streptomyces venezuelae ISP5230 with O-propargyl-L-serine led to the efficient production of an alkyne-containing jadomycin. The installed alkyne... 
ANTIBIOTICS | STREPTOMYCES-VENEZUELAE ISP5230 | ANALOGS | BIOSYNTHESIS | GLYCODIVERSIFICATION | GENERATION | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | STEPS
Journal Article
SYNTHESIS-STUTTGART, ISSN 0039-7881, 10/2011, Issue 19, pp. A91 - A93
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 05/2012, Volume 134, Issue 17, pp. 7321 - 7324
This paper demonstrates that the secondary hydroxyl can be functionalized in preference to the primary hydroxyl of a 1,2-diol. The site selectivity is achieved... 
SECONDARY ALCOHOLS | DIOLS | HYDROLYTIC KINETIC RESOLUTION | TERMINAL EPOXIDES | ENANTIOSELECTIVE SILYLATION | PROTECTION | SUGAR BIOSYNTHESIS | ACYLATION | STRATEGY | GLYCODIVERSIFICATION | CHEMISTRY, MULTIDISCIPLINARY | Alcohols - chemistry | Catalysis | Kinetics | Stereoisomerism | Chemical bonds | Glycols | Chemical properties | Analysis
Journal Article
Tetrahedron, ISSN 0040-4020, 02/2017, Volume 73, Issue 7, pp. 829 - 837
A new protocol for the synthesis of -galactal-derived -ethoxycarbonyl vinyl aziridine , starting from tri- -acetyl- -glucal, is described. The new protocol... 
Stereoselectivity | Vinyl aziridines | Glycosylation | Glycals | 4-N-(protected)-O-glycosides | OLIGOSACCHARIDES | O-GLYCOSYLATION | CHEMISTRY, ORGANIC | ALLYLIC AMINATION | SUGARS | NOSYL | CHLOROSULFONYL ISOCYANATE | GLYCODIVERSIFICATION | 4-AMINOGLYCOSIDES | C-GLYCOSIDATION | GLYCOBIOLOGY
Journal Article
Journal Article
ACS Catalysis, ISSN 2155-5435, 02/2019, Volume 9, Issue 2, pp. 1241 - 1252
Neutral drift (also called purifying selection) is an attractive approach to generate polymorphic variant libraries for enzyme engineering. Here, we have... 
amylosucrase | enzyme engineering | glycodiversification | neutral drift | transglucosylase engineering | RECOMBINATION | MUTANT | SPECIFICITY | ACTIVE-SITE | CHEMISTRY, PHYSICAL | NEISSERIA-POLYSACCHAREA AMYLOSUCRASE | DIRECTED EVOLUTION | CHEMOENZYMATIC SYNTHESIS | GLUCOSYLATION | MUTATIONS | TOOLS | Life Sciences | Biotechnology
Journal Article
MedChemComm, ISSN 2040-2503, 2014, Volume 5, Issue 8, pp. 1048 - 1057
The attachment of alkyl and other hydrophobic groups to traditional antibacterial kanamycins and neomycins creates amphiphilic aminoglycosides with altered... 
ANTIBIOTICS | CHEMISTRY, MEDICINAL | KANAMYCIN | ANTIBACTERIAL ACTIVITY | STAUDINGER REACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCODIVERSIFICATION | RESISTANCE | MECHANISMS | REGIOSELECTIVITY | DERIVATIVES | STRUCTURE-BASED DESIGN
Journal Article
Journal of Microbiology and Biotechnology, ISSN 1017-7825, 06/2018, Volume 28, Issue 6, pp. 931 - 937
Glycosyltransferases (GTs) from microbes are an emerging and rich source for efficient glycol-transformation of natural/unnatural compounds. Here, we probed... 
Marine-derived Bacillus | Macrolactin | Aglycon promiscuity | Glycoldiversification | Glycosyltransferase | glycol-diversification | macrolactin | marine-derived Bacillus | SUGAR BIOSYNTHESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | aglycon promiscuity | GLYCODIVERSIFICATION | BACTERIUM | MICROBIOLOGY | GLYCOSYLATION
Journal Article
Journal Article
Tetrahedron, ISSN 0040-4020, 09/2016, Volume 72, Issue 37, pp. 5671 - 5678
Glycosylation of molecules improve their pharmacological and pharmacokinetic properties. In the current manuscript, we have explored the effect of... 
Sugar amino acid | NMR | Cyclic peptide | Glycosylation | Conformation | DESIGN | DRUG DISCOVERY | MACROLIDE | CHEMISTRY, ORGANIC | SPONGE MYRIASTRA-CLAVOSA |