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1. Full Text Hexameric Structure and Assembly of the Interleukin-6/IL-6 α-Receptor/gp130 Complex
by Martin J. Boulanger and Dar-Chone Chow and Elena E. Brevnova and K. Christopher Garcia
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2003, Volume 300, Issue 5628, pp. 2101 - 2104
Molecules | Receptors | Cytokines | Surface areas | Reports | Titration | Epitopes | Signal reflection | Electron density | Symmetry | Crystal structure | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Structure in molecular biology | Molecular biophysics | Crystalline structure | Protein Structure, Tertiary | Receptors, Interleukin-6 - chemistry | Cytokine Receptor gp130 | Membrane Glycoproteins - metabolism | Protein Structure, Secondary | Signal Transduction | Humans | Interleukin-6 - chemistry | Membrane Glycoproteins - chemistry | Models, Molecular | Crystallography, X-Ray | Antigens, CD - metabolism | Macromolecular Substances | Thermodynamics | Protein Binding | Protein Conformation | Antigens, CD - chemistry | Binding Sites | Interleukin-6 - metabolism | Receptors, Interleukin-6 - metabolism | Cellular biology | Immunology | Index Medicus
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2. Full Text SOCS3 regulates the plasticity of gp130 signaling
by Takahashi, Yutaka and Pauleau, Anne-Laure and Parganas, Evan and Murray, Peter J and Lang, Roland and Ihle, James N and Mages, Jörg and Rutschman, Robert
Nature immunology, ISSN 1529-2908, 06/2003, Volume 4, Issue 6, pp. 546 - 550
Life Sciences & Biomedicine | Immunology | Science & Technology | Antigens, CD - immunology | Phosphorylation | Membrane Glycoproteins - metabolism | Oligonucleotide Array Sequence Analysis | Repressor Proteins | Male | Suppressor of Cytokine Signaling Proteins | Antigens, CD - metabolism | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Female | Membrane Glycoproteins - immunology | Macrophages - immunology | Trans-Activators - immunology | DNA-Binding Proteins - immunology | Cytokine Receptor gp130 | Proteins - immunology | Mice, Knockout | Suppressor of Cytokine Signaling 3 Protein | Macrophages - metabolism | Animals | Interferon-gamma - immunology | Interleukin-6 - immunology | STAT1 Transcription Factor | Trans-Activators - metabolism | Mice | STAT3 Transcription Factor | Transcription Factors | src Homology Domains - immunology | Interleukin-10 - immunology | Index Medicus
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3. Full Text Hyperactive gp130/STAT3‐driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development
by Hill, David G and Yu, Liang and Gao, Hugh and Balic, Jesse J and West, Alison and Oshima, Hiroko and McLeod, Louise and Oshima, Masanobu and Gallimore, Awen and D'Costa, Kimberley and Bhathal, Prithi S and Sievert, William and Ferrero, Richard L and Jenkins, Brendan J and Jones, Gareth W
International journal of cancer, ISSN 0020-7136, 07/2018, Volume 143, Issue 1, pp. 167 - 178
ectopic lymphoid structures | gastric cancer | tertiary lymphoid structures | STAT3 | interleukin‐17 | interleukin-17 | Life Sciences & Biomedicine | Oncology | Science & Technology | Stomach Neoplasms - genetics | Tertiary Lymphoid Structures - immunology | Prognosis | Cytokine Receptor gp130 - metabolism | Signal Transduction | Tertiary Lymphoid Structures - genetics | Cytokine Receptor gp130 - genetics | Humans | Stomach Neoplasms - metabolism | Helicobacter Infections - immunology | Helicobacter Infections - genetics | Chemokines - genetics | Stomach Neoplasms - immunology | Animals | Survival Analysis | Tertiary Lymphoid Structures - metabolism | Helicobacter Infections - metabolism | Mice | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Autoimmunity | Mobile communication systems | Wireless communication systems | Interleukins | Analysis | Inflammation | T cells | CCL19 protein | CXCL13 protein | Organs | Stat3 protein | Chronic infection | Lymphocytes T | Stomach cancer | Patients | Survival | Gastritis | Signaling | Cellular communication | Lymphocytes B | Lymphocytes | Intestine | CCL21 protein | Tumorigenesis | Gastric cancer | Chemokines | Tumors | Cancer | Glycoprotein gp130 | Index Medicus | Tumor Immunology and Microenvironment
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4. Full Text A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
by Schwerd, Tobias and Twigg, Stephen R. F and Aschenbrenner, Dominik and Manrique, Santiago and Miller, Kerry A and Taylor, Indira B and Capitani, Melania and McGowan, Simon J and Sweeney, Elizabeth and Weber, Astrid and Chen, Liye and Bowness, Paul and Riordan, Andrew and Cant, Andrew and Freeman, Alexandra F and Milner, Joshua D and Holland, Steven M and Frede, Natalie and Mueller, Miryam and Schmidt-Arras, Dirk and Grimbacher, Bodo and Wall, Steven A and Jones, E. Yvonne and Wilkie, Andrew O. M and Uhlig, Holm H
The Journal of experimental medicine, ISSN 0022-1007, 09/2017, Volume 214, Issue 9, pp. 2547 - 2562
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Interleukin-11 - deficiency | Cytokine Receptor gp130 - physiology | Exome - genetics | Cytokine Receptor gp130 - genetics | Craniosynostoses - genetics | Humans | Child, Preschool | Immunologic Deficiency Syndromes - genetics | Interleukins - deficiency | Female | Interleukin-6 - deficiency | Mutation, Missense - genetics | Leukemia | Craniosynostosis | Interleukin | Immunoglobulin E | Interleukin 27 | Substitutes | Interleukin 6 | Coding | Eczema | Skin diseases | Job's syndrome | Glycoprotein gp130 | Immunological memory | Cytokines | Abnormalities | Leukemia inhibitory factor | Immunodeficiency | Stat3 protein | Interleukin 11 | Bronchiectasis | Oncostatin M | Eosinophilia | Signaling | Analogies | Lymphocytes B | Mutation | Auditory defects | Index Medicus | 316 | 310
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5. Full Text Adipocyte-specific gp130 signalling mediates exercise-induced weight reduction
by Odermatt, Timothy S and Dedual, Mara A and Borsigova, Marcela and Wueest, Stephan and Konrad, Daniel
INTERNATIONAL JOURNAL OF OBESITY, ISSN 0307-0565, 03/2020, Volume 44, Issue 3, pp. 707 - 714
Endocrinology & Metabolism | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Obesity | Care and treatment | Interleukins | Development and progression | Cellular signal transduction | Genetic aspects | Glycoproteins | Health aspects | Adipose tissue | Physical training | Physical activity | Control methods | Interleukin | AKT protein | Body weight loss | Hypothalamus | Hormones | Adipocytes | Interleukin 6 | Proteins | Exercise | Janus kinase 2 | Genotypes | Thermography | Glycoprotein gp130 | Food | Appetite | Stat3 protein | Weight loss | Energy expenditure | Insulin | Body weight gain | Signaling | Physical fitness | Weight control | Thermogenesis | Food intake | Leptin | Weight reduction | Immunoassays | Index Medicus
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6. Full Text Coinhibition of S1PR1 and GP130 by siRNA‐loaded alginate‐conjugated trimethyl chitosan nanoparticles robustly blocks development of cancer cells
by Rostami, Narges and Nikkhoo, Afshin and Khazaei‐poul, Yalda and Farhadi, Shohreh and Sadat Haeri, Melika and Moghadaszadeh Ardebili, Sadaf and Aghaei Vanda, Nasimeh and Atyabi, Fatemeh and Namdar, Afshin and Baghaei, Masoumeh and Haghnavaz, Navideh and Kazemi, Tohid and Yousefi, Mehdi and Ghalamfarsa, Ghasem and Sabz, Gholamabas and Jadidi‐Niaragh, Farhad
Journal of cellular physiology, ISSN 0021-9541, 12/2020, Volume 235, Issue 12, pp. 9702 - 9717
alginate | GP130 | S1PR1 | nanoparticle | signal transducer and activator of transcription 3 | siRNA | trimethyl chitosan | Physiology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Nanoparticles | Development and progression | Colon cancer | Cancer cells | Cancer | Animal models | Transcription | Toxicity | Alginic acid | Interleukin | Feedback loops | Positive feedback | Signal transduction | Pathways | Feedback | Colon | Glycoprotein gp130 | Melanoma | Stat3 protein | Breast cancer | Stability analysis | Glycoproteins | Alginates | Tumor cell lines | Signaling | Chorioallantoic membrane | Zeta potential | Morphology | Polydispersity | Chitosan | Tumors | Index Medicus
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7. Full Text Osteoarthritis: Targeting gp130 aids cartilage repair
by Collison, Joanna
Nature reviews. Rheumatology, ISSN 1759-4790, 04/2018, Volume 14, Issue 4, pp. 182 - 182
Cytokine Receptor gp130 | Signal Transduction | Cartilage Diseases | Osteoarthritis | Humans | Cartilage, Articular | Glycoproteins | Cellular signal transduction | Research | Analysis | Interleukin-6 | Glycoprotein gp130 | Cartilage diseases
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8. Full Text gp130 AND THE INTERLEUKIN-6 FAMILY OF CYTOKINES
by Taga, Tetsuya and Kishimoto, Tadamitsu
Annual review of immunology, ISSN 0732-0582, 04/1997, Volume 15, Issue 1, pp. 797 - 819
cytokine | gp130 | receptor | signal transduction | interleukins | gpl30 | Life Sciences & Biomedicine | Immunology | Science & Technology | Amino Acid Sequence | Antigens, CD - immunology | Cytokine Receptor gp130 | Receptors, Interleukin - immunology | Signal Transduction | Humans | Molecular Sequence Data | Antigens, CD - genetics | Membrane Glycoproteins - genetics | Membrane Glycoproteins - physiology | Animals | Models, Biological | Interleukin-6 - immunology | Antigens, CD - physiology | Membrane Glycoproteins - immunology | Receptors, Interleukin-6 | Receptors, Cytokine - genetics | Cytokines - immunology | Index Medicus
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