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by Marouli, Eirini and Graff, Mariaelisa and Medina-Gomez, Carolina and Lo, Ken Sin and Wood, Andrew R and Kjaer, Troels R and Fine, Rebecca S and Lu, Yingchang and Schurmann, Claudia and Highland, Heather M and Rüeger, Sina and Thorleifsson, Gudmar and Justice, Anne E and Lamparter, David and Stirrups, Kathleen E and Turcot, Valérie and Young, Kristin L and Winkler, Thomas W and Esko, Tõnu and Karaderi, Tugce and Locke, Adam E and Masca, Nicholas G. D and Ng, Maggie C. Y and Mudgal, Poorva and Rivas, Manuel A and Vedantam, Sailaja and Mahajan, Anubha and Guo, Xiuqing and Abecasis, Goncalo and Aben, Katja K and Adair, Linda S and Alam, Dewan S and Albrecht, Eva and Allin, Kristine H and Allison, Matthew and Amouyel, Philippe and Appel, Emil V and Arveiler, Dominique and Asselbergs, Folkert W and Auer, Paul L and Balkau, Beverley and Banas, Bernhard and Bang, Lia E and Benn, Marianne and Bergmann, Sven and Bielak, Lawrence F and Blüher, Matthias and Boeing, Heiner and Boerwinkle, Eric and Böger, Carsten A and Bonnycastle, Lori L and Bork-Jensen, Jette and Bots, Michiel L and Bottinger, Erwin P and Bowden, Donald W and Brandslund, Ivan and Breen, Gerome and Brilliant, Murray H and Broer, Linda and Burt, Amber A and Butterworth, Adam S and Carey, David J and Caulfield, Mark J and Chambers, John C and Chasman, Daniel I and Chen, Yii-Der Ida and Chowdhury, Rajiv and Christensen, Cramer and Chu, Audrey Y and Cocca, Massimiliano and Collins, Francis S and Cook, James P and Corley, Janie and Galbany, Jordi Corominas and Cox, Amanda J and Cuellar-Partida, Gabriel and Danesh, John and Davies, Gail and de Bakker, Paul I. W and de Borst, Gert J and de Denus, Simon and de Groot, Mark C. H and de Mutsert, Renée and Deary, Ian J and Dedoussis, George and Demerath, Ellen W and den Hollander, Anneke I and Dennis, Joe G and Di Angelantonio, Emanuele and Drenos, Fotios and Du, Mengmeng and Dunning, Alison M and Easton, Douglas F and Ebeling, Tapani and Edwards, Todd L and Ellinor, Patrick T and Elliott, Paul and Evangelou, Evangelos and Farmaki, Aliki-Eleni and Faul, Jessica D and ... and The EPIC-InterAct Consortium and CHD Exome+ Consortium and GoT2D Genes Consortium and MAGIC Investigators and Global Lipids Genetics Consortium and ReproGen Consortium and ExomeBP Consortium and T2D-Genes Consortium and EPIC-CVD Consortium and EPIC-InterAct Consortium and CHD Exome Consortium
Nature (London), ISSN 1476-4687, 2017, Volume 542, Issue 7640, pp. 186 - 190
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2003, Volume 300, Issue 5624, pp. 1394 - 1399
In March 2003, a novel coronavirus (SARS-CoV) was discovered in association with cases of severe acute respiratory syndrome (SARS). The sequence of the... 
Proteins | Coronavirus | Messenger RNA | RNA | Genomics | Viruses | Amino acids | Genomes | Research Articles | Open reading frames | SARS virus | SARS Virus/chemistry/classification/genetics/isolation & purification | Genome, Viral | Amino Acid Sequence | Nucleocapsid Proteins/chemistry/genetics | Humans | Membrane Glycoproteins/chemistry/genetics | Open Reading Frames | RNA, Viral/genetics | Regulatory Sequences, Nucleic Acid | Molecular Sequence Data | RNA, Messenger/genetics/metabolism | Viral Matrix Proteins/chemistry/genetics | Coronavirus/classification/genetics | Viral Envelope Proteins/chemistry/genetics | RNA Replicase/chemistry/genetics | Severe Acute Respiratory Syndrome/virology | Endopeptidases/chemistry/genetics | Phylogeny | Sequence Analysis, DNA | Conserved Sequence | Polyproteins/chemistry/genetics | Transcription, Genetic | Viral Proteins/chemistry/genetics | DNA, Complementary | TARGETED RECOMBINATION | SPIKE GENE | VIRUS | ENTRY | TRANSMISSIBLE GASTROENTERITIS CORONAVIRUS | MULTIDISCIPLINARY SCIENCES | DETERMINANT | Coronavirus - classification | Viral Matrix Proteins - genetics | Severe Acute Respiratory Syndrome - virology | Membrane Glycoproteins - chemistry | RNA, Messenger - metabolism | SARS Virus - classification | Endopeptidases - chemistry | RNA, Viral - genetics | SARS Virus - genetics | SARS Virus - isolation & purification | Viral Envelope Proteins - genetics | RNA Replicase - genetics | Viral Proteins - chemistry | RNA, Messenger - genetics | Polyproteins - chemistry | Viral Proteins - genetics | Nucleocapsid Proteins - chemistry | Polyproteins - genetics | SARS Virus - chemistry | Membrane Glycoproteins - genetics | Spike Glycoprotein, Coronavirus | Endopeptidases - genetics | Nucleocapsid Proteins - genetics | Viral Matrix Proteins - chemistry | RNA Replicase - chemistry | Viral Envelope Proteins - chemistry | Coronavirus - genetics | Epidemics | Control | Hong Kong | DNA | Severe acute respiratory syndrome | China | Causes of | Development and progression | Coronaviruses | Research | Observations
Journal Article
Journal of Dental Research, ISSN 0022-0345, 9/2014, Volume 93, Issue 9, pp. 882 - 890
..., osteoporosis, and vitamin D deficiency (Genco and Borgnakke, 2013). The investigation of genetic factors in CP has been based on early twin and family studies (Michalowicz... 
genomics | genetics | bacteria | pathway analysis | inflammation | periodontal disease | PATHWAYS | POPULATION | SUSCEPTIBILITY | ADULTS | RECEPTOR | ATHEROSCLEROSIS RISK | CIRCADIAN CLOCK | DENTISTRY, ORAL SURGERY & MEDICINE | DISEASE | HEALTH | Prospective Studies | Tumor Necrosis Factor Decoy Receptors - genetics | Microtubule-Associated Proteins - genetics | Cytoskeletal Proteins - genetics | Atherosclerosis - genetics | Humans | Middle Aged | Apoptosis - genetics | Male | Monoacylglycerol Lipases - genetics | Receptors, Peptide - genetics | Receptors, Tumor Necrosis Factor, Member 10c | ras GTPase-Activating Proteins - genetics | Chronic Periodontitis - microbiology | Chronic Periodontitis - genetics | Adult | Female | Atherosclerosis - microbiology | Adaptor Protein Complex beta Subunits - genetics | Nuclear Proteins - genetics | Porphyromonas gingivalis - genetics | Genome-Wide Association Study | Genetic Association Studies | Membrane Proteins - genetics | Risk Factors | Linkage Disequilibrium - genetics | Potassium Channels, Tandem Pore Domain - genetics | Chromosome Mapping | Membrane Glycoproteins - genetics | Aggregatibacter actinomycetemcomitans - genetics | Adaptor Protein Complex 3 - genetics | Polymorphism, Single Nucleotide - genetics | Aged | Receptors, G-Protein-Coupled - genetics | Mucins - genetics | Cohort Studies | GPI-Linked Proteins - genetics | Research Reports
Journal Article
Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 472 - 484
Major outputs of the neocortex are conveyed by corticothalamic axons (CTAs), which form reciprocal connections with thalamocortical axons, and... 
MUTANT MICE | CORTICAL AXONS | THALAMOCORTICAL AXONS | GROWTH | SEMAPHORIN 3E | CENTRAL-NERVOUS-SYSTEM | GUIDANCE | CHICK HINDLIMB | CAJAL-RETZIUS CELLS | NEUROSCIENCES | CEREBRAL-CORTEX | Thyroid Nuclear Factor 1 | Age Factors | Embryo, Mammalian | Leukocyte L1 Antigen Complex - metabolism | Gene Expression Regulation, Developmental - genetics | Axons - physiology | Cerebral Cortex - cytology | Neural Pathways - physiology | DNA-Binding Proteins - metabolism | POU Domain Factors - genetics | tau Proteins - genetics | Thalamus - physiology | Contactin 2 - metabolism | Repressor Proteins - metabolism | Glycoproteins - genetics | Tumor Suppressor Proteins - metabolism | Wnt3A Protein - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Membrane Glycoproteins - genetics | Nerve Tissue Proteins - metabolism | S100 Calcium Binding Protein G - metabolism | Transcription Factors - metabolism | Animals | Calbindin 2 | Thalamus - cytology | Cerebral Cortex - physiology | Luminescent Proteins - genetics | Mice | Body Patterning - genetics | Luminescent Proteins - metabolism | Developmental biology | Neurons | Studies | Laboratories | Experiments | Repressor Proteins | Cerebral Cortex | Cellular Biology | Neural Pathways | tau Proteins | Life Sciences | Contactin 2 | Gene Expression Regulation, Developmental | Body Patterning | Thalamus | Membrane Glycoproteins | Luminescent Proteins | DNA-Binding Proteins | POU Domain Factors | Calcium-Binding Protein, Vitamin D-Dependent | Glycoproteins | Nerve Tissue Proteins | Nuclear Proteins | Membrane Proteins | Axons | Homeodomain Proteins | Leukocyte L1 Antigen Complex | Transcription Factors | Wnt3A Protein | Tumor Suppressor Proteins | reciprocal connections | handshake | waiting period | PlexinD1 | axon guidance | Sema3E | thalamocortical | corticothalamic
Journal Article
Nature immunology, ISSN 1529-2916, 2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific... 
UNFOLDED PROTEIN RESPONSE | PATHWAY | ER STRESS | HOST-DEFENSE | ENDOPLASMIC-RETICULUM STRESS | FRANCISELLA-TULARENSIS INFECTION | IMMUNOLOGY | LIVE VACCINE STRAIN | INFLAMMATORY RESPONSE | NEGATIVE REGULATOR | SYSTEMS BIOLOGY | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis
Journal Article
Journal Article
PLoS Genetics, ISSN 1553-7390, 06/2008, Volume 4, Issue 6, pp. e1000116 - e1000116
Journal Article
by Estrada, Karol and Styrkarsdottir, Unnur and Evangelou, Evangelos and Hsu, Yi-Hsiang and Duncan, Emma L and Ntzani, Evangelia E and Oei, Ling and Albagha, Omar M E and Amin, Najaf and Kemp, John P and Koller, Daniel L and Li, Guo and Liu, Ching-Ti and Minster, Ryan L and Moayyeri, Alireza and Vandenput, Liesbeth and Willner, Dana and Xiao, Su-Mei and Yerges-Armstrong, Laura M and Zheng, Hou-Feng and Alonso, Nerea and Eriksson, Joel and Kammerer, Candace M and Kaptoge, Stephen K and Leo, Paul J and Thorleifsson, Gudmar and Wilson, Scott G and Wilson, James F and Aalto, Ville and Alen, Markku and Aragaki, Aaron K and Aspelund, Thor and Center, Jacqueline R and Dailiana, Zoe and Duggan, David J and Garcia, Melissa and Garcia-Giralt, Natàlia and Giroux, Sylvie and Hallmans, Göran and Hocking, Lynne J and Husted, Lise Bjerre and Jameson, Karen A and Khusainova, Rita and Kim, Ghi Su and Kooperberg, Charles and Koromila, Theodora and Kruk, Marcin and Laaksonen, Marika and Lacroix, Andrea Z and Lee, Seung Hun and Leung, Ping C and Lewis, Joshua R and Masi, Laura and Mencej-Bedrac, Simona and Nguyen, Tuan V and Nogues, Xavier and Patel, Millan S and Prezelj, Janez and Rose, Lynda M and Scollen, Serena and Siggeirsdottir, Kristin and Smith, Albert V and Svensson, Olle and Trompet, Stella and Trummer, Olivia and van Schoor, Natasja M and Woo, Jean and Zhu, Kun and Balcells, Susana and Brandi, Maria Luisa and Buckley, Brendan M and Cheng, Sulin and Christiansen, Claus and Cooper, Cyrus and Dedoussis, George and Ford, Ian and Frost, Morten and Goltzman, David and González-Macías, Jesús and Kähönen, Mika and Karlsson, Magnus and Khusnutdinova, Elza and Koh, Jung-Min and Kollia, Panagoula and Langdahl, Bente Lomholt and Leslie, William D and Lips, Paul and Ljunggren, Östen and Lorenc, Roman S and Marc, Janja and Mellström, Dan and Obermayer-Pietsch, Barbara and Olmos, José M and Pettersson-Kymmer, Ulrika and Reid, David M and Riancho, José A and Ridker, Paul M and Rousseau, François and lagboom, P Eline S and Tang, Nelson L S and ... and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Nature genetics, ISSN 1546-1718, 2012, Volume 44, Issue 5, pp. 491 - 501
... the understanding of the genetic architecture of common, complex diseases (6). This approach is providing key insights into the mechanisms of disease, with prospects... 
WOMEN | GENE | VARIANTS | DISEASE | GENETICS & HEREDITY | OSTEOPOROTIC FRACTURES | LRP5 | PATTERNS | EXPRESSION | BURDEN | HIP | Glycoproteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Computational Biology | Intercellular Signaling Peptides and Proteins - genetics | European Continental Ancestry Group | Genotype | Male | Bone Density - genetics | Gene Expression Profiling | Phosphoproteins - genetics | Fractures, Bone - genetics | Mitochondrial Membrane Transport Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Female | Femur Neck - physiopathology | Osteoporosis - genetics | Spectrin - genetics | Quantitative Trait Loci | Lumbar Vertebrae - physiopathology | Quantitative trait loci | Measurement | Fractures | Bones | Genetic aspects | Identification and classification | Density | Risk factors | Medical research | Osteoporosis | Genomics | Bone density | Gene loci | Vèrtebres lumbars | Gens | Femur | Genes | Bone densitometry | Densitometria òssia | Fèmur | Lumbar vertebrae | Spectrin | Klinisk medicin | Single Nucleotide | Mitochondrial Membrane Transport Proteins | genetics | Endokrinologi och diabetes | Extracellular Matrix Proteins | Phosphoproteins | Endocrinology and Diabetes | Bone Density | Low Density Lipoprotein Receptor-Related Protein-5 | Intercellular Signaling Peptides and Proteins | Femur Neck | Glycoproteins | Clinical Medicine | physiopathology | Bone | Lumbar Vertebrae | Polymorphism
Journal Article