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Journal Article
Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4335 - 4345
Journal Article
Science, ISSN 0036-8075, 8/2011, Volume 333, Issue 6044, pp. 843 - 850
Current flu vaccines provide only limited coverage against seasonal strains of influenza viruses. The identification of V H 1-69 antibodies that broadly... 
Influenza A virus | RESEARCH ARTICLES | Vaccination | Cardiopulmonary resuscitation | Antibodies | Viruses | Orthomyxoviridae | Infections | Epitopes | H3N2 subtype influenza A virus | Crystal structure | FUSION | HEMAGGLUTININ | RECOGNITION | AVIAN INFLUENZA | SUBTYPES | MULTIDISCIPLINARY SCIENCES | VACCINATION | MONOCLONAL-ANTIBODIES | PEPTIDE | SEASON | Orthomyxoviridae Infections - prevention & control | Antibody Specificity | Humans | Molecular Sequence Data | Antigens, Viral - genetics | Crystallography, X-Ray | Neutralization Tests | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Epitopes - immunology | Antibodies, Neutralizing - immunology | Conserved Sequence | Influenza A Virus, H7N7 Subtype - immunology | Influenza A virus - immunology | Influenza, Human - therapy | Antibodies, Monoclonal - immunology | Amino Acid Sequence | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Models, Molecular | Antigens, Viral - chemistry | Antibodies, Monoclonal - isolation & purification | Influenza A Virus, H3N2 Subtype - immunology | Antibodies, Viral - isolation & purification | Antibodies, Neutralizing - isolation & purification | Antigens, Viral - immunology | Animals | Influenza Vaccines - immunology | Antibodies, Viral - immunology | Protein Conformation | Mice | Influenza A Virus, H7N7 Subtype - genetics | Mutation | Binding Sites, Antibody | Influenza, Human - prevention & control | Orthomyxoviridae Infections - immunology | Influenza, Human - immunology | Influenza viruses | Influenza vaccines | Crystals | Monoclonal antibodies | Physiological aspects | Research | Properties | Structure | Vaccines | Influenza | Public health | Virology | Index Medicus | fusion | peptide | avian influenza | hemagglutinin | recognition | monoclonal-antibodies | season | vaccination | subtypes
Journal Article
Nature Communications, ISSN 2041-1723, 09/2015, Volume 6, Issue 1, pp. 8164 - 8164
Autoimmunity and macrophage recruitment into the central nervous system (CNS) are critical determinants of neuroinflammatory diseases. However, the mechanisms... 
INTEGRIN ALPHA(M)BETA | MULTIPLE-SCLEROSIS | WHITE-MATTER | MULTIDISCIPLINARY SCIENCES | IN-VIVO | REGULATORY T-CELLS | BINDING-SITE | CENTRAL-NERVOUS-SYSTEM | MICE | CNS AUTOIMMUNITY | GAMMA-C-DOMAIN | Immunohistochemistry | Myelin-Oligodendrocyte Glycoprotein - immunology | Cell Proliferation | Chemokine CCL2 - immunology | Demyelinating Diseases - genetics | Encephalomyelitis, Autoimmune, Experimental - immunology | Gene Expression Profiling | Brain - metabolism | Autoimmunity - immunology | Demyelinating Diseases - immunology | Fibrinogen - pharmacology | Receptors, Antigen, T-Cell - immunology | Fibrinogen - immunology | Receptors, Chemokine - genetics | DNA-Binding Proteins - immunology | Rats | Antigen Presentation - genetics | Antigen Presentation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Microglia | Brain - drug effects | Genes, MHC Class II - genetics | Spinal Cord - immunology | Fibrin | Adaptive Immunity - drug effects | Brain - pathology | Mice | CX3C Chemokine Receptor 1 | Blood-Brain Barrier | Spinal Cord - drug effects | Spinal Cord - metabolism | Autoimmunity - genetics | Genes, MHC Class II - immunology | Homeodomain Proteins - immunology | Th1 Cells - immunology | Adaptive Immunity - genetics | CD11b Antigen - genetics | Flow Cytometry | Spinal Cord - pathology | Chemokine CXCL10 - immunology | Adaptive Immunity - immunology | Macrophages - immunology | CD11b Antigen - immunology | Receptors, Chemokine - immunology | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | Chemokine CXCL10 - genetics | Antigen Presentation - drug effects | Brain - immunology | Autoimmunity - drug effects | Chemokines | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 499 - 510
Journal Article
Mucosal Immunology, ISSN 1933-0219, 01/2016, Volume 9, Issue 1, pp. 24 - 37
HIV-1-associated disruption of intestinal homeostasis is a major factor contributing to chronic immune activation and inflammation. Dendritic cells (DCs) are... 
TRANSLOCATION | RESPONSES | LYMPHOID-TISSUE | INFLAMMATION | PREDICT MORTALITY | IMMUNE ACTIVATION | ANTIRETROVIRAL THERAPY | INTESTINAL LAMINA PROPRIA | IMMUNOLOGY | VIRUS TYPE-1 INFECTION | SIV INFECTION | Antigens, CD - immunology | Immunoglobulins - immunology | Dendritic Cells - immunology | Humans | Middle Aged | Colon - immunology | Male | Immunoglobulins - genetics | Antigens, CD - genetics | Case-Control Studies | Viral Load | Ruminococcus - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | HIV Infections - microbiology | Prevotella - immunology | HIV Infections - pathology | Prevotella - growth & development | Adult | Female | CD40 Antigens - genetics | Interferon-gamma - genetics | Membrane Glycoproteins - immunology | Ruminococcus - growth & development | Glycoproteins - genetics | Antigens, CD1 - immunology | CD4-Positive T-Lymphocytes - microbiology | CD8-Positive T-Lymphocytes - microbiology | Signal Transduction | Lymphocyte Activation | Gene Expression Regulation | Membrane Glycoproteins - genetics | Glycoproteins - immunology | HIV-1 - immunology | Mucous Membrane - immunology | Interferon-gamma - immunology | Dendritic Cells - microbiology | Colon - microbiology | Antigens, CD1 - genetics | Gastrointestinal Microbiome - immunology | CD8-Positive T-Lymphocytes - immunology | CD40 Antigens - immunology | Mucous Membrane - microbiology | Cell Lineage - immunology | Index Medicus | mucosal immunology | HIV-1 pathogenesis | microbiome | Human intestinal dendritic cells
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 411 - 418
Sensors of pathogens, such as Toll-like receptors (TLRs), detect microbes to activate transcriptional programs that orchestrate adaptive responses to specific... 
UNFOLDED PROTEIN RESPONSE | PATHWAY | ER STRESS | HOST-DEFENSE | ENDOPLASMIC-RETICULUM STRESS | FRANCISELLA-TULARENSIS INFECTION | IMMUNOLOGY | LIVE VACCINE STRAIN | INFLAMMATORY RESPONSE | NEGATIVE REGULATOR | SYSTEMS BIOLOGY | RNA, Small Interfering - genetics | Endoribonucleases - genetics | Tularemia - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lipopeptides - pharmacology | Transcriptional Activation - drug effects | NADPH Oxidases - metabolism | Tularemia - genetics | Protein Splicing - genetics | Transcriptional Activation - immunology | X-Box Binding Protein 1 | Protein Splicing - drug effects | NADPH Oxidases - genetics | Stress, Physiological - drug effects | TNF Receptor-Associated Factor 6 - genetics | Transcription Factor CHOP - biosynthesis | Transcription Factors - immunology | Cytokines - genetics | Protein-Serine-Threonine Kinases - metabolism | DNA-Binding Proteins - immunology | Endoribonucleases - metabolism | Macrophages - pathology | Stress, Physiological - genetics | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 4 - genetics | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Macrophages - metabolism | Signal Transduction - drug effects | Tunicamycin - pharmacology | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | Mice | Stress, Physiological - immunology | Endoribonucleases - immunology | Transcription Factor CHOP - genetics | NADPH Oxidases - immunology | DNA-Binding Proteins - metabolism | Signal Transduction - immunology | Macrophages - virology | Mice, Mutant Strains | Tularemia - immunology | Membrane Glycoproteins - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Francisella tularensis - immunology | Protein Splicing - immunology | Protein-Serine-Threonine Kinases - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | NADPH Oxidase 2 | Regulatory Factor X Transcription Factors | Mice, Inbred C3H | Membrane Glycoproteins - genetics | Transcription Factors - metabolism | Animals | TNF Receptor-Associated Factor 6 - metabolism | Macrophages - drug effects | Protein-Serine-Threonine Kinases - immunology | Francisella tularensis - pathogenicity | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Cell receptors | Transcription factors | Immune response | Physiological aspects | Genetic aspects | Research | Health aspects | Francisella tularensis | Index Medicus
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7467, pp. 439 - 443
Broadly neutralizing antibodies reactive against most and even all variants of the same viral species have been described for influenza and HIV-1 (ref. 1).... 
IN-VITRO | MEMORY B-CELLS | TRACT DISEASE | MULTIDISCIPLINARY SCIENCES | HUMAN METAPNEUMOVIRUS | FUSION PROTEIN | ELECTRON-MICROSCOPY | INFECTION | RESPIRATORY SYNCYTIAL VIRUS | YOUNG-CHILDREN | F-GLYCOPROTEIN | Humans | Immunoglobulin Variable Region - chemistry | Paramyxoviridae - classification | Pneumovirus Infections - prevention & control | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Immunoglobulin Variable Region - immunology | Respiratory Syncytial Virus Infections - immunology | Viral Fusion Proteins - immunology | Murine pneumonia virus - immunology | Epitopes - immunology | Immunoglobulin Light Chains - chemistry | Antibodies, Neutralizing - immunology | Antibody Specificity - immunology | Paramyxoviridae Infections - virology | Viral Fusion Proteins - chemistry | Cattle | Antibodies, Neutralizing - therapeutic use | Respiratory Syncytial Virus Infections - prevention & control | Respiratory Syncytial Virus, Bovine - immunology | Respiratory Syncytial Virus Infections - virology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Immunoglobulin Light Chains - immunology | Amino Acid Sequence | Metapneumovirus - immunology | Paramyxoviridae Infections - therapy | Models, Molecular | Antibodies, Monoclonal - isolation & purification | Cross Reactions - immunology | Pneumovirus Infections - virology | Antibodies, Neutralizing - isolation & purification | Paramyxoviridae Infections - immunology | Pneumovirus Infections - immunology | Paramyxoviridae - immunology | Animals | Respiratory Syncytial Virus, Human - immunology | Antibodies, Neutralizing - chemistry | Viral Vaccines - chemistry | Mice | Paramyxoviridae Infections - prevention & control | Respiratory Syncytial Virus Infections - therapy | Viral Vaccines - immunology | Monoclonal antibodies | Paramyxoviruses | Control | Health aspects | Proteins | Competition | Viruses | Glycoproteins | Infections | Mutation | Index Medicus
Journal Article