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Journal Article
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 09/2003, Volume 112, Issue 5, pp. 670 - 682
Bacillus anthracis lethal toxin (LT) is the major virulence factor of anthrax and reproduces most of the laboratory manifestations of the disease in animals.... 
KINASE-KINASE | MEDICINE, RESEARCH & EXPERIMENTAL | FAS LIGAND | FACTOR CLEAVES | INHALATIONAL ANTHRAX | BIOTERRORISM EXPOSURE | IN-VIVO | NITRIC-OXIDE | N-TERMINUS | PROTECTIVE ANTIGEN | ENDOTHELIAL GROWTH-FACTOR | cytokines | lethal factor
Journal Article
Biometrics, ISSN 0006-341X, 09/2004, Volume 60, Issue 3, pp. 684 - 693
We present an adaptive Bayesian method for dose-finding in phase I/II clinical trials based on trade-offs between the probabilities of treatment efficacy and... 
Dose-finding | Adaptive design | Bayesian design | Phase II clinical trial | Phase I clinical trial | Biologic agents | Biometrics | Health outcomes | Algorithms | Physicians | Clinical trials | Experimentation | Strokes | Graft vs host disease | Dosage | Parametric models | Dose‐finding | MATHEMATICS, INTERDISCIPLINARY APPLICATIONS | biologic agents | MODELS | phase II clinical trial | BIOLOGY | STATISTICS & PROBABILITY | OUTCOMES | I/II CLINICAL-TRIALS | adaptive design | dose-finding | phase I clinical trial | Antibodies, Monoclonal - toxicity | Pentostatin - administration & dosage | Clinical Trials, Phase I as Topic - statistics & numerical data | Humans | Tissue Plasminogen Activator - administration & dosage | Stroke - drug therapy | Immunoglobulin Fab Fragments - toxicity | Models, Statistical | Biometry | Recombinant Proteins - administration & dosage | Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors | Dose-Response Relationship, Drug | Immunoglobulin Fab Fragments - administration & dosage | Graft vs Host Disease - drug therapy | Antibodies, Monoclonal - administration & dosage | Bayes Theorem | Clinical Trials, Phase II as Topic - statistics & numerical data | Recombinant Proteins - toxicity | Pentostatin - toxicity | Tissue Plasminogen Activator - toxicity | Bone marrow | Transplants & implants | Toxicity | Bayesian analysis | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
The American Journal of Forensic Medicine and Pathology, ISSN 0195-7910, 12/2015, Volume 36, Issue 4, pp. 268 - 270
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 501, Issue 7465, pp. 102 - 106
Journal Article