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1. Full Text Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation
by Wang, Yicheng and Maeda, Yusuke and Liu, Yi-Shi and Takada, Yoko and Ninomiya, Akinori and Hirata, Tetsuya and Fujita, Morihisa and Murakami, Yoshiko and Kinoshita, Taroh
Nature communications, ISSN 2041-1723, 02/2020, Volume 11, Issue 1, pp. 860 - 860
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Galactosyltransferases - deficiency | Glycosylphosphatidylinositols - biosynthesis | Acyltransferases - deficiency | Endoplasmic Reticulum-Associated Degradation - genetics | Glycosphingolipids - biosynthesis | Glycosylphosphatidylinositols - genetics | Humans | Models, Molecular | Galactosyltransferases - genetics | Glycosphingolipids - genetics | Galactosyltransferases - metabolism | Recombinant Fusion Proteins - chemistry | Acyltransferases - metabolism | Gene Knockout Techniques | Acyltransferases - genetics | Recombinant Fusion Proteins - metabolism | CRISPR-Cas Systems | HEK293 Cells | Recombinant Fusion Proteins - genetics | HeLa Cells | CRISPR | Membranes | N-Acetylgalactosamine | Genes | Control systems | Chains | Biosynthesis | Genomes | Ganglioside GM1 | Cell surface | Genetic screening | Golgi apparatus | Degradation | Proteins | Glycosphingolipids | Quality control | Plasma membranes | Glycosylphosphatidylinositol | Galactose | Endoplasmic reticulum | Index Medicus
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2. Full Text Stem Cells Derived from Human Fetal Membranes Display Multilineage Differentiation Potential
by Sivakami Ilancheran and Anna Michalska and Gary Peh and Euan M. Wallace and Martin Pera and Ursula Manuelpillai
Biology of Reproduction, ISSN 0006-3363, 2007, Volume 77, Issue 3, pp. 577 - 588
stem cells | placenta | fetal membranes | developmental biology | amnion | Amnion | Fetal membranes | Placenta | Developmental biology | Stem cells | Life Sciences & Biomedicine | Reproductive Biology | Science & Technology | Immunohistochemistry | Fetal Stem Cells - cytology | Fetal Stem Cells - metabolism | Humans | Multipotent Stem Cells - metabolism | Octamer Transcription Factor-3 - biosynthesis | Male | Glycosphingolipids - genetics | HMGB Proteins - biosynthesis | Octamer Transcription Factor-3 - genetics | Stem Cell Transplantation | RNA, Messenger - biosynthesis | Flow Cytometry | HMGB Proteins - genetics | Female | Histocompatibility Antigens Class I - biosynthesis | SOXB1 Transcription Factors | Cell Differentiation - physiology | Homeodomain Proteins - biosynthesis | Nanog Homeobox Protein | Glycosphingolipids - biosynthesis | RNA, Messenger - genetics | Histocompatibility Antigens Class II - biosynthesis | Transcription Factors - biosynthesis | Histocompatibility Antigens Class I - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Amnion - physiology | Homeodomain Proteins - genetics | Animals | Multipotent Stem Cells - cytology | Mice | Histocompatibility Antigens Class II - genetics | DNA-Binding Proteins - biosynthesis | Stage-Specific Embryonic Antigens | Index Medicus
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3. Full Text Gangliosides: Structures, Biosynthesis, Analysis, and Roles in Cancer
by Groux‐Degroote, Sophie and Guérardel, Yann and Delannoy, Philippe
Chembiochem : a European journal of chemical biology, ISSN 1439-4227, 07/2017, Volume 18, Issue 13, pp. 1146 - 1154
gangliosides | glycosyltransferases | cancer | immunology | glycosphingolipids | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Membrane Microdomains - metabolism | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Sialic Acids - chemistry | Neoplasms - therapy | Gangliosides - biosynthesis | Neoplasms - genetics | Immunotherapy | Sialyltransferases - antagonists & inhibitors | Gangliosides - chemistry | Carbohydrate Sequence | Gangliosides - antagonists & inhibitors | Signal Transduction | Sialic Acids - metabolism | Sialyltransferases - genetics | Membrane Microdomains - chemistry | Cell Adhesion - drug effects | Sialyltransferases - metabolism | Disease Progression | Animals | Membrane Microdomains - drug effects | Neoplasms - immunology | Cell Proliferation - drug effects | Carbohydrate Conformation | Neoplasms - pathology | Analysis | Physiological aspects | Development and progression | Biosynthesis | Cellular signal transduction | Gangliosides | Cancer | Residues | Ectoderm | Rafts | Mass spectroscopy | Lipid rafts | Phospholipids | Cholesterol | Glycan | Cell adhesion & migration | Membrane proteins | Proteins | Signal transduction | Glycosphingolipids | Pathways | Modulation | Cell adhesion | Signal processing | Mass spectrometry | Index Medicus
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4. Full Text Reconstitution of glucosylceramide flip-flop across endoplasmic reticulum: Implications for mechanism of glycosphingolipid biosynthesis
by Chalat, Madhavan and Menon, Indu and Turan, Zeynep and Menon, Anant K
The Journal of biological chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 19, pp. 15523 - 15532
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Microsomes, Liver - metabolism | Proteolipids - metabolism | Endoplasmic Reticulum - metabolism | Octoxynol - chemistry | Phospholipid Transfer Proteins - metabolism | Biological Transport | Membrane Transport Proteins - metabolism | Membrane Proteins - metabolism | Glucosylceramides - chemistry | Glycosphingolipids - biosynthesis | Rats | Microsomes, Liver - chemistry | Liposomes - chemistry | Animals | Models, Biological | Transport Vesicles - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Golgi Apparatus - metabolism | Liposomes - metabolism | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Glucosylceramides - metabolism | Intracellular Membranes - metabolism | Glycosphingolipids - chemistry | Proteolipids - chemistry | Index Medicus | Membrane Biology | Phospholipid | Flippase | FAPP2 | Membrane Reconstitution | Lipid Transport | Glycerophospholipid | Glycosphingolipid | Glucosylceramide | Reticulon | Reconstitution of Membrane Transporters | Yop1 | Endoplasmic Reticulum (ER)
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5. Full Text Human genetic disorders of sphingolipid biosynthesis
by Astudillo, Leonardo and Astudillo, Leonardo and Sabourdy, Frédérique and Sabourdy, Frédérique and Therville, Nicole and Therville, Nicole and Bode, Heiko and Bode, Heiko and Ségui, Bruno and Ségui, Bruno and Andrieu-Abadie, Nathalie and Andrieu-Abadie, Nathalie and Hornemann, Thorsten and Hornemann, Thorsten and Levade, Thierry and Levade, Thierry
Journal of inherited metabolic disease, ISSN 0141-8955, 1/2015, Volume 38, Issue 1, pp. 65 - 76
Human Genetics | Biochemistry, general | Pediatrics | Internal Medicine | Medicine & Public Health | Metabolic Diseases | Sphingolipids - biosynthesis | Lipid Metabolism, Inborn Errors - genetics | Glycosphingolipids - biosynthesis | Humans | Paraplegia - genetics | Retinitis - genetics | Phenotype | Animals | Epilepsy - genetics | Mice | Mutation | Ataxia - genetics | Peripheral Nervous System Diseases - genetics | Disease Models, Animal | Enzymes | Nervous system diseases | Analysis | Epilepsy | Physiological aspects | Ceramides | Lipids | Index Medicus
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6. Full Text Apicobasal domain identities of expanding tubular membranes depend on glycosphingolipid biosynthesis
by Zhang, Hongjie and Abraham, Nessy and Khan, Liakot A and Hall, David H and Fleming, John T and Göbel, Verena
Nature cell biology, ISSN 1465-7392, 10/2011, Volume 13, Issue 10, pp. 1189 - 1201
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Coenzyme A Ligases - genetics | Caenorhabditis elegans Proteins - metabolism | Serine C-Palmitoyltransferase - genetics | Acetyl-CoA Carboxylase - genetics | Coenzyme A Ligases - metabolism | Alcohol Oxidoreductases - genetics | Glucosyltransferases - metabolism | RNA Interference | Time Factors | Intestinal Mucosa - enzymology | Cell Membrane - metabolism | Glucosyltransferases - genetics | Caenorhabditis elegans - metabolism | Hydroxylation | Intestinal Mucosa - ultrastructure | Caenorhabditis elegans - genetics | Glycosphingolipids - biosynthesis | Epithelial Cells - ultrastructure | Alcohol Oxidoreductases - metabolism | Genotype | Cell Membrane - ultrastructure | Cell Enlargement | Serine C-Palmitoyltransferase - metabolism | Caenorhabditis elegans - ultrastructure | Cell Membrane - enzymology | Cell Polarity - genetics | Microscopy, Confocal | Phenotype | Animals | Transport Vesicles - metabolism | Epithelial Cells - enzymology | Caenorhabditis elegans Proteins - genetics | Acetyl-CoA Carboxylase - metabolism | Caenorhabditis elegans - enzymology | Microscopy, Fluorescence | Physiological aspects | Enzymes | Cell membranes | Sphingolipids | Research | Index Medicus
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7. Full Text Inhibition of glycosphingolipid biosynthesis reduces secretion of the β-amyloid precursor protein and amyloid β-peptide
by Tamboli, Irfan Y and Prager, Kai and Barth, Esther and Heneka, Michael and Sandhoff, Konrad and Walter, Jochen
The Journal of biological chemistry, ISSN 0021-9258, 07/2005, Volume 280, Issue 30, pp. 28110 - 28117
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Rhodamines - pharmacology | Immunoprecipitation | Humans | Brain - metabolism | Endocytosis | Biological Transport | Melanoma, Experimental | Time Factors | Gangliosides - metabolism | Amyloid beta-Peptides - metabolism | Cell Membrane - metabolism | Cell Line | Biotinylation | Peptides - chemistry | Lipid Metabolism | Cholesterol - metabolism | Blotting, Western | Animals | Glycosphingolipids - antagonists & inhibitors | Alzheimer Disease - metabolism | Cell Line, Tumor | Glycosphingolipids - metabolism | Golgi Apparatus - metabolism | Mice | HeLa Cells | Glycosphingolipids - chemistry | Index Medicus
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8. Full Text Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias
by Salustiano, Eduardo J and da Costa, Kelli M and Freire-de-Lima, Leonardo and Mendonca-Previato, Lucia and Previato, Jose O
The Journal of biological chemistry, ISSN 0021-9258, 05/2020, Volume 295, Issue 19, pp. 6457 - 6471
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Glucosyltransferases - antagonists & inhibitors | Drug Resistance, Multiple | Glycosphingolipids - blood | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Drug Resistance, Neoplasm | Glycosphingolipids - genetics | Neoplasm Proteins - metabolism | Pyrrolidines - pharmacology | Glucosyltransferases - metabolism | ATP-Binding Cassette Transporters - genetics | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | K562 Cells | ATP-Binding Cassette Transporters - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Neoplasm Proteins - genetics | Propanolamines - pharmacology | Glucosyltransferases - genetics | Index Medicus
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