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chemistry, multidisciplinary (30) 30
gene expression (30) 30
amino acid sequence (29) 29
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glycoside hydrolases - antagonists & inhibitors (29) 29
microbial sensitivity tests (29) 29
microbiology (29) 29
bacterial proteins - metabolism (28) 28
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anti-bacterial agents - chemistry (27) 27
binding (27) 27
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n-acetylglucosaminyltransferases - antagonists & inhibitors (26) 26
oligosaccharides (26) 26
pharmacology & pharmacy (26) 26
galactosyltransferases - antagonists & inhibitors (24) 24
rats (24) 24
antibiotics (23) 23
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gene (23) 23
glucosyltransferases - antagonists & inhibitors (23) 23
n-acetylglucosaminyltransferases - metabolism (23) 23
oligosaccharides - chemistry (23) 23
life sciences (22) 22
magnetic resonance spectroscopy (22) 22
penicillin-binding proteins (22) 22
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peptidoglycan glycosyltransferase - antagonists & inhibitors (21) 21
signal transduction (21) 21
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biochemistry, general (20) 20
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complex (20) 20
cricetinae (20) 20
enzyme inhibitors - metabolism (20) 20
fucosyltransferases - antagonists & inhibitors (20) 20
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BMC Microbiology, ISSN 1471-2180, 04/2018, Volume 18, Issue 1, pp. 1 - 14
Background: Changes in nutrient availability have dramatic and well-defined impacts on both transcription and translation in bacterial cells. At the same time,... 
Cell division | ClpP | Cell size | UgtP | Cell cycle | UDP-glucose | LIPOTEICHOIC ACID | ESCHERICHIA-COLI | GROWTH-RATE | CELL-SIZE | MICROBIOLOGY | PROTEOLYSIS | CHAPERONE ACTIVITY | IRON HOMEOSTASIS | MEMBRANE-DERIVED OLIGOSACCHARIDES | TRANSCRIPTION FACTOR | ADAPTER PROTEIN | Gene mutations | Bacillus subtilis | Proteases | Analysis | Glycosyltransferases | Research
Journal Article
mBio, ISSN 2161-2129, 01/2019, Volume 10, Issue 1, p. e01912-18
Peptidoglycan (PG) is an essential constituent of the bacterial cell wall. During cell division, PG synthesis localizes at midcell under the control of a... 
FtsN | divisome | peptidoglycan | FtsBLQ | PBP1b | lipid II | Peptidoglycan | Lipid II | Divisome | LOCALIZATION | COMPLEX | ESCHERICHIA-COLI | MICROBIOLOGY | GLYCOSYLTRANSFERASE ACTIVITY | CYTOKINETIC RING | TRANSPEPTIDASE | CONSTRICTION | CELL-DIVISION PROTEIN | DOMAINS | PENICILLIN-BINDING PROTEIN-1A
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2009, Volume 106, Issue 22, pp. 8824 - 8829
Drug-resistant bacteria have caused serious medical problems in recent years, and the need for new antibacterial agents is undisputed. Transglycosylase, a... 
Proteins | Antibiotics | Molecular structure | Cell walls | Drug interactions | Escherichia coli | Crystals | Lipids | Bacteria | Crystal structure | Peptidoglycan synthesis | Membrane protein structure | Protein-protein interaction | Antibacterial development | Antibiotic resistance | ANTIBIOTICS | DESIGN | DOMAIN | LYTIC TRANSGLYCOSYLASE | PROTEIN-STRUCTURE | MULTIDISCIPLINARY SCIENCES | MODEL | membrane protein structure | antibacterial development | REPAIR | antibiotic resistance | MOENOMYCIN | protein-protein interaction | BINDING | CELL-WALL PEPTIDOGLYCAN | peptidoglycan synthesis | Amino Acid Sequence | Escherichia coli - enzymology | Peptidoglycan Glycosyltransferase - chemistry | Molecular Sequence Data | Crystallography, X-Ray | Serine-Type D-Ala-D-Ala Carboxypeptidase - chemistry | Penicillin-Binding Proteins - chemistry | Serine-Type D-Ala-D-Ala Carboxypeptidase - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Oligosaccharides - chemistry | Protein Conformation | Peptidoglycan Glycosyltransferase - antagonists & inhibitors | Escherichia coli Proteins - antagonists & inhibitors | Penicillin-Binding Proteins - antagonists & inhibitors | Escherichia coli Proteins - chemistry | Physiological aspects | Properties | Bacterial proteins | Membrane proteins | Ionizing radiation | Enzymatic activity | Drug resistance | Protein interaction | Antibacterial agents | penicillin-binding protein 1b | moenomycin | Biological Sciences | Physical Sciences | protein–protein interaction
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2012, Volume 8, Issue 7, pp. 661 - 668
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 02/2017, Volume 56, Issue 6, pp. 886 - 895
Heptosyltransferase I (HepI) catalyzes the addition of l-glycero-β-d-manno-heptose to Kdo2-Lipid A, as part of the biosynthesis of the core region of... 
LIPOPOLYSACCHARIDE BIOSYNTHESIS | FLUORESCENCE SPECTROSCOPY | CIRCULAR-DICHROISM | CONFORMATIONAL-CHANGES | ENZYME | WAAC | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | INHIBITORS | GLYCOSYLTRANSFERASES | Solvents - chemistry | Tryptophan - chemistry | Surface Properties | Apoenzymes - metabolism | Escherichia coli Proteins - antagonists & inhibitors | Glycosyltransferases - genetics | Binding Sites | Circular Dichroism | Lipid A - chemistry | Apoenzymes - antagonists & inhibitors | Acylation | Recombinant Proteins - metabolism | Biocatalysis | Escherichia coli - enzymology | Mutagenesis, Site-Directed | Lipid A - metabolism | Glycosyltransferases - chemistry | Enzyme Stability | Solubility | Models, Molecular | Recombinant Proteins - chemistry | Spectrometry, Fluorescence | Escherichia coli Proteins - metabolism | Molecular Dynamics Simulation | Glycosyltransferases - metabolism | Apoenzymes - genetics | Apoenzymes - chemistry | Escherichia coli Proteins - genetics | Protein Conformation | Mutation | Escherichia coli Proteins - chemistry | Amino Acid Substitution | Glycosyltransferases - antagonists & inhibitors | Proteins | Usage | Escherichia coli | Analysis | Fluorescence | Molecular dynamics | Catalysis | Research | Circular dichroism | Index Medicus | structural rearrangement | GT-B | glycosyltransferase | protein dynamics | circular dichroism | Heptosyltransferase | tryptophan fluorescence
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 2014, Volume 50, Issue 3, pp. 583 - 594
Glycosaminoglycan (GAG) chains of proteoglycans (PGs) play important roles in fibrosis through cell-matrix interactions and growth factor binding in the... 
Fibroblasts | Bleomycin | Glycosaminoglycans | Proteoglycans | Up-Regulation | Fibroblasts - enzymology | Chondroitin Sulfates - metabolism | Transforming Growth Factor beta1 - antagonists & inhibitors | Transforming Growth Factor beta1 - metabolism | Male | Pulmonary Fibrosis - genetics | Pentosyltransferases - metabolism | RNA, Messenger - metabolism | Lung - enzymology | Transfection | Time Factors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Sulfotransferases - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Glycosyltransferases - genetics | Glycosaminoglycans - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Lung - pathology | Signal Transduction | Glycosaminoglycans - metabolism | Cells, Cultured | Rats | Antibodies, Neutralizing - pharmacology | Pulmonary Fibrosis - pathology | Transforming Growth Factor beta1 - genetics | Fibroblasts - pathology | Rats, Sprague-Dawley | Gene Expression Regulation, Enzymologic | Glycosyltransferases - metabolism | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Glucuronosyltransferase - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Lung - drug effects | Pulmonary Fibrosis - enzymology | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Pulmonary Fibrosis - prevention & control | Pulmonary Fibrosis - chemically induced | Protein Kinase Inhibitors - pharmacology | Versicans - metabolism
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 46, pp. 18909 - 18914
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2004, Volume 48, Issue 1, pp. 30 - 40
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
SCINTILLATION PROXIMITY ASSAY | MEMBRANE-ASSOCIATED STEPS | K-12 | ACETYLMURAMYL-PENTAPEPTIDE | BIOSYNTHESIS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | POLYMERIZATION | RESISTANT STAPHYLOCOCCUS-AUREUS | D-ALANINE CARBOXYPEPTIDASE | BACTERIAL PEPTIDOGLYCAN | CELL-WALL PEPTIDOGLYCAN | Escherichia coli - drug effects | Hexosyltransferases - metabolism | Muramoylpentapeptide Carboxypeptidase - metabolism | Penicillin-Binding Proteins | Ristocetin - pharmacology | Vancomycin - pharmacology | Wheat Germ Agglutinins | Transferases - antagonists & inhibitors | Muramoylpentapeptide Carboxypeptidase - antagonists & inhibitors | Peptidyl Transferases - antagonists & inhibitors | Bacterial Proteins - antagonists & inhibitors | Detergents - pharmacology | Drug Evaluation, Preclinical - methods | Bacterial Outer Membrane Proteins | Peptidyl Transferases - metabolism | Escherichia coli - enzymology | Carrier Proteins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Hexosyltransferases - antagonists & inhibitors | Peptidoglycan - biosynthesis | Glycosyltransferases - metabolism | Carrier Proteins - metabolism | N-Acetylglucosaminyltransferases - antagonists & inhibitors | Bacterial Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Glycosyltransferases - antagonists & inhibitors | Mechanisms of Action | Physiological Effects
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 11, p. e48598
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 06/2017, Volume 25, Issue 12, pp. 3182 - 3194
Journal Article