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Journal of Ethnopharmacology, ISSN 0378-8741, 07/2015, Volume 169, pp. 1 - 7
Journal Article
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2017, Volume 24, Issue 1, pp. 40 - 50
Amphotericin B (AMB) is used most commonly in severe systemic life-threatening fungal infections. There is currently an unmet need for an efficacious (AMB)... 
PLGA-PEG | nanoparticles | Amphotericin B | nephrotoxicity | bioavailability | oral delivery | efficacy | Nanoparticles | Oral delivery | Efficacy | Bioavailability | Nephrotoxicity | DRUG-DELIVERY-SYSTEM | HEMOLYTIC-ACTIVITY | AGGREGATION STATE | LOADED PLGA NANOPARTICLES | PEG NANOPARTICLES | POLYMERIC MICELLES | GLYCYRRHIZIC ACID | FORMULATIONS | PHARMACOLOGY & PHARMACY | IN-VIVO EVALUATION | VISCERAL LEISHMANIASIS | Hemolysis - drug effects | Blood Urea Nitrogen | Biological Availability | Polyethylene Glycols - chemistry | Polyglycolic Acid - toxicity | Antifungal Agents - chemistry | Candida albicans - growth & development | Amphotericin B - toxicity | Drug Carriers | Microbial Sensitivity Tests | Candida albicans - drug effects | Antifungal Agents - pharmacokinetics | Kidney Diseases - chemically induced | Amphotericin B - administration & dosage | Drug Compounding | Amphotericin B - pharmacokinetics | Kidney Diseases - blood | Amphotericin B - chemistry | Antifungal Agents - toxicity | Glycyrrhizic Acid - administration & dosage | Lactic Acid - chemistry | Administration, Oral | Glycyrrhizic Acid - chemistry | Technology, Pharmaceutical - methods | Biomarkers - blood | Polyethylene Glycols - toxicity | Rats, Sprague-Dawley | Animals | Polyglycolic Acid - chemistry | Creatinine - blood | Lactic Acid - toxicity | Antifungal Agents - administration & dosage | Rodents | Index Medicus
Journal Article
Journal Article
Journal Article
Molecules, ISSN 1420-3049, 11/2017, Volume 22, Issue 11, p. 1853
An attempt was made to characterize the pharmacokinetic profiles of Qishen Keli (QSKL) that has been widely proved to be effective in clinical practice. A... 
Simultaneous determination | Polarity-switching multiple reaction monitoring | Multi-component pharmacokinetics | Qishen Keli | Ultra-high performance liquid chromatography | WIDE POLARITY | INTEGRATED PLATFORM | simultaneous determination | polarity-switching multiple reaction monitoring | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRESYSTEMIC METABOLISM | COMPONENTS | ultra-high performance liquid chromatography | CANCER | CHEMISTRY, MULTIDISCIPLINARY | GLYCYRRHIZIC ACID | LC-MS/MS | GLYCYRRHETINIC ACID | SUBJECT | multi-component pharmacokinetics | TARGETED QUANTITATIVE-ANALYSIS | Glycyrrhizic Acid - administration & dosage | Administration, Oral | Glycyrrhetinic Acid - pharmacokinetics | Glycyrrhizic Acid - pharmacokinetics | Glycyrrhetinic Acid - administration & dosage | Glycyrrhetinic Acid - analysis | Rats | Male | Chromatography, High Pressure Liquid | Plant Extracts - administration & dosage | Drugs, Chinese Herbal - pharmacokinetics | Plant Extracts - analysis | Tandem Mass Spectrometry | Animals | Plant Extracts - pharmacokinetics | Plasma - chemistry | Molecular Structure | Glycyrrhizic Acid - analysis | Drugs, Chinese Herbal - analysis | Spectroscopy | Elution | Oral administration | Ions | Mass spectroscopy | Pharmacology | Selectivity | Liquid chromatography | High-performance liquid chromatography | Chromatography | Switching | Acids | Formic acid | Linearity | Acetonitrile | Polarity | Scientific imaging | Mass spectrometry | High performance liquid chromatography | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 11/2012, Volume 164, Issue 1, pp. 17 - 25
Journal Article
Phytomedicine, ISSN 0944-7113, 07/2016, Volume 23, Issue 8, pp. 864 - 871
Glycyrrhetinic acid (GA) and paeoniflorin (PF) are the main active ingredients in Chinese peony- Liquorice Decoction, a widely used Traditional Chinese... 
Transdermal drug delivery | Paeoniflorin | Pharmacodynamics | Analgesic | Pharmacokinetics | Glycyrrhetinic acid | CHEMISTRY, MEDICINAL | MORPHINE | TOLERANCE | MECHANISMS | RELEASE | CONTRACTIONS | PLANT SCIENCES | GLYCYRRHIZIC ACID | PAIN | INTEGRATIVE & COMPLEMENTARY MEDICINE | SYNOVIOCYTES | PHARMACOLOGY & PHARMACY | SHAKUYAKUKANZOTO | Dysmenorrhea - drug therapy | Thiazines - administration & dosage | Drugs, Chinese Herbal - pharmacology | Thiazoles - administration & dosage | Glucosides - pharmacokinetics | Administration, Cutaneous | Thiazoles - pharmacokinetics | Tissue Distribution | Monoterpenes - pharmacology | Glycyrrhetinic Acid - pharmacology | Monoterpenes - pharmacokinetics | Thiazines - pharmacology | Anti-Inflammatory Agents - administration & dosage | Anti-Inflammatory Agents - pharmacokinetics | Female | Monoterpenes - administration & dosage | Drugs, Chinese Herbal - administration & dosage | Disease Models, Animal | Thiazines - pharmacokinetics | Transdermal Patch | Glucosides - pharmacology | Anti-Inflammatory Agents - pharmacology | Glycyrrhetinic Acid - pharmacokinetics | Glycyrrhetinic Acid - administration & dosage | Skin Absorption | Drug Synergism | Drugs, Chinese Herbal - pharmacokinetics | Animals | Glucosides - administration & dosage | Mice | Thiazoles - pharmacology | Care and treatment | Analysis | Peonies | Pharmacology | Health aspects | Dysmenorrhea | Materia medica, Vegetable | Plant extracts | Index Medicus
Journal Article
International Journal of Nanomedicine, ISSN 1176-9114, 03/2013, Volume 8, Issue 1, pp. 1207 - 1222
Introduction: The livertaxis of glycyrrhizic acid-conjugated bovine serum albumin (GL-BSA) has been reported in the literature. Now, in this paper, we describe... 
BSA | High-pressure homogenization emulsification | GL | HCPT | CELLS | RAT HEPATOCYTES | INDUCED APOPTOSIS | BSA NANOPARTICLES | NANOSCIENCE & NANOTECHNOLOGY | CHITOSAN NANOPARTICLES | CANCER | high-pressure homogenization emulsification | THERAPY | IN-VITRO EVALUATION | PHARMACOLOGY & PHARMACY | OPTIMIZATION | SURFACE METHODOLOGY RSM | Hemolysis - drug effects | Camptothecin - chemistry | Nanoparticles - chemistry | Serum Albumin, Bovine - administration & dosage | Humans | Drug Carriers - administration & dosage | Drug Carriers - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Carcinoma, Hepatocellular - drug therapy | Cattle | Camptothecin - administration & dosage | Serum Albumin, Bovine - chemistry | Antineoplastic Agents, Phytogenic - pharmacokinetics | Camptothecin - analogs & derivatives | Camptothecin - pharmacokinetics | Rabbits | Glycyrrhizic Acid - administration & dosage | Liver Neoplasms - drug therapy | Glycyrrhizic Acid - chemistry | Antineoplastic Agents, Phytogenic - chemistry | Particle Size | Animals | Liver Neoplasms - metabolism | Cell Line, Tumor | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Carcinoma, Hepatocellular - metabolism | Drugs | Camptothecin | Drug delivery systems | Hepatoma | Research | Drug therapy | Health aspects | Vehicles | Nanoparticles | Liver cancer | Particle size | Efficiency | Spectrum analysis | Homogenization | Index Medicus | Original Research
Journal Article
Journal Article
Journal of Antimicrobial Chemotherapy, ISSN 0305-7453, 08/2012, Volume 67, Issue 8, pp. 1905 - 1914
The aim of the present study was to characterize glycyrrhizic acid (GA) and assess its immunomodulatory potential in a model of experimental visceral... 
Prostaglandin E2 | Cytokines | Macrophages | Immunomodulators | Nitric oxide | IMMUNE-RESPONSE | INFECTIOUS DISEASES | nitric oxide | MICROBIOLOGY | DRUG-RESISTANCE | macrophages | INTERFERON-GAMMA | prostaglandin E2 | MURINE LEISHMANIASIS | EXPERIMENTAL VISCERAL LEISHMANIASIS | NITRIC-OXIDE | GENE-EXPRESSION | immunomodulators | PHARMACOLOGY & PHARMACY | cytokines | NF-KAPPA-B | LICORICE ROOT | UP-REGULATION | Nitric Oxide Synthase Type II - biosynthesis | Gene Expression Profiling | Cyclooxygenase 2 - biosynthesis | Macrophages - parasitology | Glycyrrhizic Acid - pharmacology | Anti-Inflammatory Agents - administration & dosage | Real-Time Polymerase Chain Reaction | Glycyrrhizic Acid - administration & dosage | Leishmania donovani - immunology | Enzyme-Linked Immunosorbent Assay | Anti-Inflammatory Agents - pharmacology | Cytokines - secretion | Immunologic Factors - administration & dosage | Leishmania donovani - pathogenicity | Treatment Outcome | Leishmaniasis, Visceral - drug therapy | Dinoprostone - metabolism | Spleen - parasitology | Animals | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Liver - parasitology | Nitric Oxide - metabolism | Immunologic Factors - pharmacology | Proteins | Chemotherapy | Parasitic protozoa | Infectious diseases | Gene expression | Index Medicus | Cell proliferation | Spleen | Animal models | Immunomodulation | Liver | Transforming growth factor | Interleukin 12 | Inflammation | Lymphocytes T | Scintillation | Parasites | Transforming growth factor- beta | Nitric-oxide synthase | Western blotting | Infection | Polymerase chain reaction | Visceral leishmaniasis | Interleukin 10 | Cyclooxygenase-2 | Enzyme-linked immunosorbent assay | Tumor necrosis factor- alpha
Journal Article
Journal Article