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Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7500, pp. 361 - 365
T cells discriminate between foreign and host molecules by recognizing distinct microbial molecules, predominantly peptides and lipids(1-4). Riboflavin... 
RIBOFLAVIN | SYNTHASE | DESIGN | RECOGNITION | VITAMIN-B METABOLITES | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | SALMONELLA-TYPHIMURIUM | RECEPTOR | MR1 | T-Lymphocyte Subsets - immunology | Immunity, Mucosal - immunology | Pyrimidines - immunology | Vitamin B Complex - immunology | Glyoxal - metabolism | T-Lymphocyte Subsets - cytology | Minor Histocompatibility Antigens | Humans | Molecular Conformation | Antigens, Bacterial - immunology | Amino Sugars - immunology | Pyrimidines - chemistry | Pyrimidines - metabolism | Histocompatibility Antigens Class I - metabolism | Pyruvaldehyde - metabolism | Lymphocyte Activation - immunology | Riboflavin - metabolism | Uracil - immunology | Uracil - chemistry | Riboflavin - biosynthesis | Antigens, Bacterial - chemistry | Glyoxal - chemistry | Histocompatibility Antigens Class I - immunology | Models, Molecular | Riboflavin - immunology | Antigen Presentation - immunology | Histocompatibility Antigens Class I - chemistry | Immunity, Innate - immunology | Metabolic Networks and Pathways | Mucous Membrane - immunology | Amino Sugars - metabolism | Schiff Bases - chemistry | Ligands | Uracil - metabolism | Amino Sugars - chemistry | Pyruvaldehyde - chemistry | Vitamin B Complex - metabolism | Antigens, Bacterial - metabolism | Uracil - analogs & derivatives | Antigens | Immune response | Physiological aspects | Physiological research | Research | T cells | Properties | T cell receptors | Mutation | Metabolites | Bacteriology
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 06/2004, Volume 22, Issue 6, pp. 695 - 700
Journal Article
FASEB Journal, ISSN 0892-6638, 10/2007, Volume 21, Issue 12, pp. 3096 - 3106
Purpose: Low molecular weight carbonyl compounds, such as the alpha-ketoaldehydes methylglyoxal (MGO) and glyoxal (GO), are formed under hyperglycemic... 
Oxidative stress | Wound healing | Growth arrest | MGO | Apoptosis | wound healing | ACTIVATION | GLYCOXIDATION | ACCELERATED ATHEROSCLEROSIS | MAILLARD REACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | N-EPSILON-(CARBOXYMETHYL)LYSINE | CELL BIOLOGY | BIOLOGY | growth arrest | CARDIOVASCULAR-DISEASE | MESANGIAL CELLS | COMPLICATIONS | GROWTH-FACTOR | PROTEINS | oxidative stress | Cell Proliferation | Diabetes Complications | Glyoxal - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Aorta - metabolism | Mesoderm - cytology | Receptor, Platelet-Derived Growth Factor beta - genetics | Apolipoproteins E - metabolism | Cell Movement - physiology | Atherosclerosis - etiology | Pyruvaldehyde - metabolism | Diabetes Mellitus, Experimental | Guanidines - metabolism | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Rabbits | Atherosclerosis - pathology | Proto-Oncogene Proteins c-sis | Cells, Cultured | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Platelet-Derived Growth Factor - metabolism | Animals | Apolipoproteins E - genetics | Glycation End Products, Advanced - metabolism | Mesoderm - metabolism | Mice | Aorta - cytology | Arginine - metabolism | Receptor, Platelet-Derived Growth Factor beta | Mesoderm | Guanidines | Glyoxal | Myocytes, Smooth Muscle | Arginine | Atherosclerosis | Glycosylation End Products, Advanced | Aorta | Platelet-Derived Growth Factor | Apolipoproteins E | Protein-Tyrosine Kinases | Pyruvaldehyde | Cell Movement
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e41309
Aging of retinal pigment epithelial (RPE) cells of the eye is marked by accumulations of bisretinoid fluorophores; two of the compounds within this lipofuscin... 
LIPOFUSCIN FLUOROPHORE | OXIDATIVE STRESS | PIGMENT EPITHELIAL-CELLS | A2E | RPE | MULTIDISCIPLINARY SCIENCES | FACTOR-H POLYMORPHISM | ALPHA-OXOALDEHYDES | BRUCHS MEMBRANE | PROTEINS | GLYCATION END-PRODUCTS | Retinoids - metabolism | Retina - metabolism | Glyoxal - metabolism | Enzyme-Linked Immunosorbent Assay | Retinal Drusen - metabolism | Humans | Cells, Cultured | Retinaldehyde - metabolism | Retinaldehyde - analogs & derivatives | Macular Degeneration - metabolism | Pyruvaldehyde - metabolism | Phenylhydrazines - metabolism | Spectrometry, Mass, Electrospray Ionization | Glycation End Products, Advanced - metabolism | Chromatography, Liquid | Pyridinium Compounds - metabolism | Guanidines - metabolism | Lipofuscin - metabolism | Retina - pathology | Macular degeneration | Proteins | Physiological aspects | Liquid chromatography | Ionization | Oxidative stress | Radiation | Irradiated | Fluorescence | Retina | Aldehydes | Eye | Rodents | Atherosclerosis | Pigments | Aging | Oxidation | Localization | Enzyme-linked immunosorbent assay | Age | Photodegradation | Photosensitivity | Diabetes mellitus | Mass spectroscopy | Glycoproteins | Glycosylation | Chemical compounds | Age related diseases | Arteriosclerosis | Fluorophores | Irradiation | Diabetes | Pyruvaldehyde | Mass spectrometry | Photooxidation | Structure-function relationships
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2015, Volume 290, Issue 45, pp. 27215 - 27227
Journal Article
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 08/2010, Volume 192, Issue 16, pp. 4205 - 4214
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 07/2012, Volume 21, Issue 14, pp. 3215 - 3225
Human DJ-1 is a genetic cause of early-onset Parkinsons disease (PD), although its biochemical function is unknown. We report here that human DJ-1 and its... 
OXIDATIVE STRESS | CAENORHABDITIS-ELEGANS | MITOCHONDRIAL LOCALIZATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | GENETICS & HEREDITY | GLYCATION | ALPHA-SYNUCLEIN | DOPAMINERGIC-NEURONS | PARKINSONS-DISEASE | PROTEIN DJ-1 | Caenorhabditis elegans - chemistry | Oncogene Proteins - genetics | Glyoxal - metabolism | Caenorhabditis elegans Proteins - chemistry | Humans | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Neurons - cytology | Intracellular Signaling Peptides and Proteins - metabolism | Pyruvaldehyde - metabolism | Aldehyde Oxidoreductases - chemistry | Neurons - metabolism | Parkinson Disease - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Amino Acid Sequence | Cell Line | Oncogene Proteins - chemistry | Caenorhabditis elegans - genetics | Mice, Inbred C57BL | Oncogene Proteins - metabolism | Rats | Aldehyde Oxidoreductases - genetics | Parkinson Disease - genetics | Aldehyde Oxidoreductases - metabolism | Mice, Knockout | Peroxiredoxins | Protein Deglycase DJ-1 | Sequence Alignment | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Neurons - enzymology | Parkinson Disease - enzymology | Mice | Kinetics | Caenorhabditis elegans Proteins - genetics | Caenorhabditis elegans - enzymology | Apoptosis | Glutamic acid | Cysteine | Dopamine | Parkinson's disease | Neurodegenerative diseases | Neurons | carbonyls | Embryo fibroblasts | PARK7 protein | Intestine | Neurodegeneration | Lactic acid | Pyruvaldehyde | Age | Movement disorders | Glutathione
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 11/1999, Volume 344, Issue 1, pp. 109 - 116
The glycation of proteins by glucose has been linked to the development of diabetic complications and other diseases. Early glycation is thought to involve the... 
COLLAGEN | autoxidation | MAILLARD REACTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARGININE RESIDUES | Amadori rearrangement | GLYCOSYLATION | IDENTIFICATION | CROSS-LINKS | PRODUCTS | PHYSIOLOGICAL CONDITIONS | COMPLICATIONS | advanced glycation endproduct | fructosamine | MODEL FRUCTOSAMINE
Journal Article
Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6347, pp. 208 - 211
Journal Article