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Journal of Controlled Release, ISSN 0168-3659, 12/2015, Volume 219, pp. 224 - 236
Nanoparticle anticancer drug delivery enhances therapeutic efficacies and reduces side effects by improving pharmacokinetics and biodistributions of the drug... 
Combination therapy of cancer | Co-delivery | Synergistic effect | Hybrid nanoparticle | IRON-OXIDE NANOPARTICLES | GOLD NANOPARTICLES | PHOTODYNAMIC THERAPY | CONTRAST AGENTS | MESOPOROUS SILICA NANOPARTICLES | NANOSCALE COORDINATION POLYMERS | MAGNETIC NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | OVERCOME DRUG-RESISTANCE | BREAST-CANCER | METAL-ORGANIC FRAMEWORKS | PHARMACOLOGY & PHARMACY | Polymers - administration & dosage | Gold - administration & dosage | Nanoparticles - chemistry | Humans | Ferric Compounds - administration & dosage | Ferric Compounds - chemistry | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Drug Delivery Systems | Organosilicon Compounds - administration & dosage | Polymers - therapeutic use | Organosilicon Compounds - therapeutic use | Nanoparticles - therapeutic use | Organometallic Compounds - therapeutic use | Gold - chemistry | Antineoplastic Agents - chemistry | Neoplasms - drug therapy | Animals | Organosilicon Compounds - chemistry | Ferric Compounds - therapeutic use | Gold - therapeutic use | Organometallic Compounds - chemistry | Polymers - chemistry | Nanoparticles - administration & dosage | Drug Combinations | Organometallic Compounds - administration & dosage | Nanoparticles | Drugs | Drug delivery systems | Chemotherapy | Analysis | Permeability | Health aspects | Cancer | Vehicles | Drug resistance | Photochemotherapy | co-delivery | combination therapy of cancer | synergistic effect
Journal Article
Advanced Materials, ISSN 0935-9648, 08/2014, Volume 26, Issue 31, pp. 5550 - 5557
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2011, Volume 152, Issue 1, pp. 76 - 83
Multidrug resistance (MDR) is characterized by the overexpression of ATP-binding cassette (ABC) transporters that actively pump a broad class of hydrophobic... 
Chemotherapy | Drug efflux | Glioma | Theranostics | Brain tumors | GOLD NANOPARTICLES | CELLS | TARGETED GENE DELIVERY | DRUG-DELIVERY | TRANSFECTION EFFICIENCY | TUMOR | POLYETHYLENIMINE | MAGNETIC NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | SUPERPARAMAGNETIC NANOPARTICLES | PHARMACOLOGY & PHARMACY | ABC TRANSPORTERS | Drug Resistance, Multiple | Metal Nanoparticles - chemistry | Solubility | Rats | Drug Resistance, Neoplasm | Ferric Compounds - administration & dosage | Ferric Compounds - chemistry | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Brain Neoplasms - drug therapy | Doxorubicin - pharmacokinetics | Antibiotics, Antineoplastic - administration & dosage | Particle Size | Tissue Distribution | Animals | Metal Nanoparticles - administration & dosage | Polyethyleneimine - chemistry | Cell Line, Tumor | Glioma - drug therapy | Doxorubicin - administration & dosage | Hydrogen-Ion Concentration | Nanoparticles | Drug resistance in microorganisms | Anthracyclines | Iron compounds | Ferric oxide | Gliomas | Polyols | Cancer | Drugs | Multidrug resistance | iron oxides | amines | Hydrophobicity | Drug resistance | pH effects | Doxorubicin | nanoparticles | Anthracycline | Antibiotics | Lability | Polyethylene glycol | Glioma cells | ABC transporter | Controlled release | Tumors | theranostics | glioma | drug efflux | brain tumors | chemotherapy
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 2009, Volume 236, Issue 1, pp. 16 - 24
In general, gold nanoparticles are recognized as being as nontoxic. Still, there have been some reports on their toxicity, which has been shown to depend on... 
Inflammation | Pharmacokinetics | Intravenous injection | Gold nanoparticles | Accumulation | CELLS | PHARMACOLOGY & PHARMACY | MICE | TOXICOLOGY | CYTOTOXICITY | Injections, Intravenous | Apoptosis - drug effects | Chlorides - toxicity | Gold Compounds - administration & dosage | Male | Polyethylene Glycols - chemistry | Spleen - drug effects | RNA, Messenger - metabolism | Tissue Distribution | Liver - immunology | Liver - drug effects | Inflammation Mediators - metabolism | Gold Compounds - toxicity | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - etiology | Neutrophil Infiltration - drug effects | Acute Disease | Liver - ultrastructure | Liver - metabolism | Spleen - ultrastructure | Chemical and Drug Induced Liver Injury - immunology | Particle Size | Animals | Spleen - metabolism | Chlorides - administration & dosage | Mice | Mice, Inbred BALB C | Chlorides - pharmacokinetics | Gold Compounds - pharmacokinetics | Metal Nanoparticles | Nanoparticles | Engineering schools | Disease transmission | Biomedical engineering | Index Medicus | TRANSMISSION ELECTRON MICROSCOPY | APOPTOSIS | RETICULOENDOTHELIAL SYSTEM | MACROPHAGES | BLOOD CIRCULATION | INTRAVENOUS INJECTION | NANOSTRUCTURES | TOXICITY | IN VIVO | 60 APPLIED LIFE SCIENCES | LYSOSOMES | SPLEEN | INFLAMMATION | LIVER
Journal Article
Nanomedicine, ISSN 1743-5889, 04/2016, Volume 11, Issue 7, pp. 783 - 796
Background: While carbon-encapsulated iron carbide nanoparticles exhibit strong magnetic properties appealing for biomedical applications, potential side... 
blood purification | long-term study | targeted drug delivery | magnetic nanoparticles | GOLD NANOPARTICLES | ASBESTOS WORKERS 1978-2005 | METAL NANOMAGNETS | NANOSCIENCE & NANOTECHNOLOGY | DELIVERY | FUNCTIONALIZATION | OXIDE NANOPARTICLES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COBALT NANOPARTICLES | LATENCY PERIOD | Drug Carriers - adverse effects | Carbon Compounds, Inorganic - pharmacokinetics | Nanoparticles - analysis | Nanoparticles - chemistry | Drug Carriers - administration & dosage | Male | Iron Compounds - pharmacokinetics | Nanoparticles - adverse effects | Carbon - chemistry | Drug Carriers - chemistry | Liver - drug effects | Iron Compounds - chemistry | Lung - ultrastructure | Female | Carbon Compounds, Inorganic - administration & dosage | Lung - metabolism | Iron Compounds - adverse effects | Liver - ultrastructure | Coated Materials, Biocompatible - adverse effects | Liver - metabolism | Mice, Inbred C57BL | Coated Materials, Biocompatible - administration & dosage | Coated Materials, Biocompatible - chemistry | Magnets - chemistry | Carbon - administration & dosage | Magnets - adverse effects | Carbon - pharmacokinetics | Carbon Compounds, Inorganic - chemistry | Carbon Compounds, Inorganic - adverse effects | Animals | Iron Compounds - administration & dosage | Lung - drug effects | Drug Carriers - pharmacokinetics | Mice | Nanoparticles - administration & dosage | Carbon - adverse effects | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e84248
Since the serendipitous discovery of cisplatin, platinum-based drugs have become well-established antitumor agents, despite the fact that their clinical use is... 
20S PROTEASOME | DESIGN | CANCER CELLS | MULTIDISCIPLINARY SCIENCES | COMPLEXES | OLIGOPEPTIDES | BORTEZOMIB | GOLD(III) DITHIOCARBAMATE DERIVATIVES | PROTEASOME INHIBITORS | COUPLED PEPTIDE TRANSPORTERS | APOPTOSIS INDUCERS | Free Radical Scavengers - pharmacology | Apoptosis - drug effects | Humans | Antineoplastic Agents - administration & dosage | Molecular Targeted Therapy | Peptidomimetics - administration & dosage | Thiocarbamates - pharmacology | Chromans - pharmacology | Organogold Compounds - administration & dosage | Drug Design | Female | Antineoplastic Agents - pharmacology | Molecular Structure | Drug Evaluation, Preclinical | Organogold Compounds - chemistry | Disease Models, Animal | Peptidomimetics - pharmacology | Thiocarbamates - administration & dosage | Proteasome Inhibitors - pharmacology | Peptidomimetics - chemistry | Cisplatin - pharmacology | Thiocarbamates - chemistry | Antineoplastic Agents - chemistry | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Organogold Compounds - pharmacology | Tumor Burden - drug effects | Breast Neoplasms - pathology | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Proteasome Endopeptidase Complex - metabolism | Chemotherapy | Peptides | Health aspects | Cancer | Drugs | Delivery systems | Clinical trials | Homeostasis | Oncology | Biochemistry | Metastasis | Kinases | Cancer therapies | Anticancer properties | Proteins | Antitumor agents | Platinum | Xenografts | Cell cycle | Inhibition | Sulfur | Gold | Enzymes | Medical research | Departments | Cultures | Breast cancer | Pharmacology | Shrinkage | Cisplatin | Medicine | Pathology | Chemistry | Side effects | Peptidomimetics | Breast | Ligands | Drug discovery | Prostate cancer | Apoptosis
Journal Article