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Journal Article
Autophagy, ISSN 1554-8627, 11/2016, Volume 12, Issue 11, pp. 2213 - 2229
Journal Article
Plant Physiology, ISSN 0032-0889, 9/2015, Volume 169, Issue 1, pp. 266 - 282
Lack of sufficient water is a major limiting factor to crop production worldwide, and the development of drought-tolerant germplasm is needed to improve crop... 
Receptors | Hypocotyls | FOCUS ON ETHYLENE | Plant roots | Corn | Plants | Drought | Transgenes | Transgenic plants | Hybridity | Seedlings | REGULATOR | ORGAN GROWTH | PROTEIN | CELL EXPANSION | RESPONSE PATHWAY | THALIANA | RECEPTOR | WHEAT | EXPRESSION | ETR1 | PLANT SCIENCES | Arabidopsis - physiology | Genes, Plant | Golgi Apparatus - drug effects | Adaptation, Physiological - drug effects | Endoplasmic Reticulum - metabolism | Arabidopsis Proteins - metabolism | Seeds - growth & development | Adaptation, Physiological - genetics | Droughts | Endoplasmic Reticulum - drug effects | Plants, Genetically Modified | Ethylenes - biosynthesis | Zea mays - physiology | Plant Proteins - metabolism | Ethylenes - pharmacology | Zea mays - genetics | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Seeds - drug effects | Zea mays - drug effects | Signal Transduction - genetics | Down-Regulation - drug effects | Mutation - genetics | Down-Regulation - genetics | Arabidopsis - genetics | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Signal Transduction - drug effects | Golgi Apparatus - metabolism | Intracellular Membranes - drug effects | Intracellular Membranes - metabolism | Arabidopsis thaliana | Botanical research | Hardiness | Ethylene | Physiological aspects | Environmental aspects | Research | s - Focus Issue
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2010, Volume 11, Issue 5, pp. 404 - 410
Influenza virus, a negative-stranded RNA virus that causes severe illness in humans and animals, stimulates the inflammasome through the Nod-like receptor... 
A VIRUS | STRANDED-RNA | PROTEIN | CASPASE-1 | IMMUNE-RESPONSES | INNATE | RIG-I | INFECTION | IMMUNOLOGY | NALP3 INFLAMMASOME | CYTOPLASMIC DNA | Membrane Glycoproteins - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Golgi Apparatus - drug effects | Ion Channels - genetics | Protein Transport - drug effects | Hydrogen-Ion Concentration - drug effects | Viral Matrix Proteins - metabolism | Cytokines - genetics | Carrier Proteins - immunology | Toll-Like Receptor 7 - metabolism | Macrophages - pathology | Monensin - pharmacology | Mice, Knockout | Macrophages - metabolism | Genetic Engineering | Mice | Viral Matrix Proteins - immunology | Orthomyxoviridae - physiology | Ion Channels - immunology | Protons | Viral Matrix Proteins - genetics | Orthomyxoviridae Infections - physiopathology | Dendritic Cells - pathology | Oncogene Proteins, Viral - pharmacology | Golgi Apparatus - virology | Macrophages - virology | Potassium Chloride - pharmacology | Toll-Like Receptor 7 - immunology | Dendritic Cells - drug effects | Membrane Glycoproteins - immunology | Dendritic Cells - virology | Dendritic Cells - metabolism | Macrophages - immunology | Toll-Like Receptor 7 - genetics | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Ion Channels - metabolism | Virus Replication | Golgi Apparatus - metabolism | Macrophages - drug effects | Orthomyxoviridae - pathogenicity | Orthomyxoviridae Infections - immunology | Sequence Deletion - genetics | Influenza viruses | Receptors | Viral proteins | Physiological aspects | Viruses | Ion channels | Research | Health aspects
Journal Article
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7713, pp. 269 - 273
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3254 - 3267
Hepatitis C virus (HCV) relies on host lipids and lipid droplets for replication and morphogenesis. The accumulation of lipid droplets in infected hepatocytes... 
TARGET | liver injury | OXIDATIVE STRESS | SREBP | hepatitis virus | CHOLESTEROL | INTERLEUKIN-1-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipid metabolism | NLRP3 inflammasome | DROPLETS | inflammation | PATHWAY | inflammasome | FATTY-ACID | CASPASES | INFECTION | EXPRESSION | Hepatitis C, Chronic - pathology | Inflammasomes - metabolism | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Golgi Apparatus - drug effects | Humans | Hepatitis C, Chronic - virology | Non-alcoholic Fatty Liver Disease - etiology | Caspase 1 - metabolism | Host-Pathogen Interactions - drug effects | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | Sterol Regulatory Element Binding Protein 1 - agonists | RNA Interference | Hepacivirus - physiology | Sterol Regulatory Element Binding Protein 2 - metabolism | Endopeptidases - metabolism | Carrier Proteins - antagonists & inhibitors | Serine Endopeptidases - chemistry | Cysteine Proteinase Inhibitors - pharmacology | Cell Line, Tumor | Hepatocytes - virology | Sterol Regulatory Element Binding Protein 2 - agonists | Hepatitis C, Chronic - metabolism | Hepatitis C, Chronic - physiopathology | Hepatocytes - pathology | Golgi Apparatus - pathology | Hepatocytes - metabolism | Golgi Apparatus - virology | Caspase 1 - chemistry | Proteolysis - drug effects | Endopeptidases - chemistry | Inflammasomes - drug effects | Enzyme Induction - drug effects | Cytoskeletal Proteins - metabolism | Membrane Proteins - metabolism | Hepatocytes - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Hepacivirus - drug effects | Proprotein Convertases - metabolism | Proprotein Convertases - chemistry | Carrier Proteins - genetics | Carrier Proteins - metabolism | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Lipogenesis - drug effects | Golgi Apparatus - metabolism | Serine Endopeptidases - metabolism | Microbiology
Journal Article
Diabetes, ISSN 0012-1797, 02/2013, Volume 62, Issue 2, pp. 444 - 456
Phosphoinositide 3-kinase (PI3K) mediates insulin actions by relaying signals from insulin receptors (IRs) to downstream targets. The p110 alpha catalytic... 
B-CELL | PHOSPHATIDYLINOSITOL 3-KINASE | KINASE | GROWTH | ENDOCRINOLOGY & METABOLISM | EMBRYONIC LETHALITY | METABOLIC-REGULATION | RKTG | PI 3-KINASE | DOMAINS | SUBUNIT | Golgi Apparatus - enzymology | Class Ia Phosphatidylinositol 3-Kinase - metabolism | Phosphorylation | Golgi Apparatus - drug effects | Humans | Glycogen Synthase Kinase 3 beta | Male | Muscle, Skeletal - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Insulin Receptor Substrate Proteins - metabolism | Phosphatidylinositols - biosynthesis | Glucose Transporter Type 4 - physiology | Hepatocytes - cytology | Gene Deletion | Muscle, Skeletal - drug effects | Biological Transport - drug effects | Biological Transport - genetics | Proto-Oncogene Proteins c-akt - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Hepatocytes - drug effects | Insulin - pharmacology | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation - physiology | Glycogen Synthase Kinase 3 - metabolism | Intracellular Signaling Peptides and Proteins - biosynthesis | Hep G2 Cells | Gene Expression Regulation - drug effects | Insulin - metabolism | Animals | Signal Transduction - drug effects | Glucose - metabolism | Receptor, Insulin - metabolism | Signal Transduction - physiology | Biological Transport - physiology | Mice | Signal Transduction
Journal Article
Plant Physiology, ISSN 0032-0889, 07/2017, Volume 174, Issue 3, pp. 1576 - 1594
Prenylated Rab acceptor1 (PRA1) functions in the recruitment of prenylated Rab proteins to their cognate organelles. Arabidopsis (Arabidopsis thaliana)... 
ATPASE ACTIVITY | PLANT-CELLS | VACUOLAR TRAFFICKING | VESICULAR TRANSPORT | ENDOPLASMIC-RETICULUM | BREFELDIN-A | PLASMA-MEMBRANE | BULK FLOW | INTRACELLULAR TRAFFICKING | ENDOMEMBRANE SYSTEM | PLANT SCIENCES | Arabidopsis - growth & development | Sodium Chloride - pharmacology | Vesicular Transport Proteins - metabolism | Golgi Apparatus - drug effects | Plant Development - drug effects | Vacuoles - drug effects | Plant Development - genetics | Gene Knockdown Techniques | Plant Roots - drug effects | Arabidopsis Proteins - metabolism | Seeds - growth & development | Plants, Genetically Modified | Membrane Proteins - metabolism | Stress, Physiological - drug effects | Golgi Apparatus - ultrastructure | Plant Roots - growth & development | Green Fluorescent Proteins - metabolism | Protein Prenylation - drug effects | Arabidopsis - drug effects | Membrane Proteins - secretion | Seeds - drug effects | Stress, Physiological - genetics | Arabidopsis - ultrastructure | Cell Membrane - ultrastructure | Mutation - genetics | Arabidopsis - metabolism | Cell Membrane - enzymology | Sodium-Potassium-Exchanging ATPase - metabolism | Vacuoles - metabolism | Golgi Apparatus - metabolism | SNARE Proteins - metabolism | Hydrogen-Ion Concentration | Arabidopsis thaliana | Physiological aspects | Guanosine triphosphatase | Golgi apparatus
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 697 - 710
Macrophages possess numerous mechanisms to combat microbial invasion, including sequestration of essential nutrients, like zinc (Zn). The pleiotropic cytokine... 
ACTIVATION | HOMEOSTASIS | METALLOTHIONEIN | GROWTH | GENE-EXPRESSION | CALPROTECTIN | IMMUNOLOGY | PROTEINS | ZINC | HISTOPLASMA-CAPSULATUM | FAMILY | Phagosomes - microbiology | Zinc - metabolism | Golgi Apparatus - drug effects | Humans | STAT5 Transcription Factor - immunology | NADPH Oxidases - immunology | Histoplasma - drug effects | Histoplasmosis - microbiology | Superoxides - immunology | Histoplasmosis - immunology | STAT5 Transcription Factor - genetics | Phagosomes - immunology | Superoxides - metabolism | NADPH Oxidases - genetics | Zinc - immunology | Cation Transport Proteins - genetics | Golgi Apparatus - immunology | Macrophages, Peritoneal - drug effects | STAT3 Transcription Factor - genetics | Metallothionein - immunology | Phagosomes - drug effects | Signal Transduction | Gene Expression Regulation | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Macrophages, Peritoneal - immunology | Mice, Transgenic | Macrophage Activation | Histoplasma - immunology | Host-Pathogen Interactions | Histoplasmosis - metabolism | Animals | Golgi Apparatus - microbiology | Macrophages, Peritoneal - microbiology | Metallothionein - genetics | Mice | STAT3 Transcription Factor - immunology | Cation Transport Proteins - immunology | Oxidases | Zinc compounds | Superoxide | Molecular genetics | Macrophages | Environmental health | Experiments | Exports | Proteomics | Streptococcus infections
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2018, Volume 13, Issue 11, p. e0206123
Autosomal-dominant, early-onset DYT1 dystonia is associated with an in-frame deletion of a glutamic acid codon (Delta E) in the TOR1A gene. The gene product,... 
MESSENGER-RNAS | SUBTLE MICROSTRUCTURAL CHANGES | FLUORESCENT CERAMIDE ANALOG | DYT1 DYSTONIA | KNOCK-IN MOUSE | TORSINA | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM | MEMBRANE-PROTEINS | SYNAPTIC PLASTICITY | SECRETORY PATHWAY | Autoantigens - metabolism | Molecular Chaperones - metabolism | Golgi Apparatus - drug effects | Fluorescence | Brefeldin A - pharmacology | Dystonia - genetics | Cell Nucleus - metabolism | Gene Deletion | Membrane Proteins - metabolism | Neurons - metabolism | Neurons - drug effects | Cell Survival - drug effects | Dendrites - drug effects | Dendrites - metabolism | Neostriatum - pathology | Ceramides - metabolism | Cells, Cultured | Molecular Chaperones - genetics | Hippocampus - pathology | Gene Knock-In Techniques | Animals | Image Processing, Computer-Assisted | Golgi Apparatus - metabolism | Mice | Cell Nucleus - drug effects | Genetic aspects | Corticosteroids | Dystonia | Glutamate | Neurons | Genes | Gene mutations | Physiological aspects | Research | Risk factors | Golgi apparatus | Glutamic acid | Cell culture | Brain | Neurosciences | Trafficking | Brefeldin A | Otolaryngology | Staining | Confocal microscopy | Gene deletion | Western blotting | Cell adhesion & migration | Proteins | Clonal deletion | Neostriatum | Ceramide | Deletion | Fibroblasts | Physiology | Protein transport | Localization | Genotypes | Neurological disorders | Age | Engineering schools | Secretion | Cortex | Biophysics | Medicine | Microscopy | Morphology | Light microscopy | Mutation | Adenosine triphosphatase | Hippocampus
Journal Article