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Circulation Research, ISSN 0009-7330, 09/2015, Volume 117, Issue 8, pp. 731 - 741
...) metabolism, and evolocumab can lower LDL cholesterol (LDL-C) to low levels. OBJECTIVE:To determine the effects of evolocumab on vitamin E and steroid hormone levels... 
PCSK9 protein | Gonadal hormones | Adrenal steroid hormones | Vitamin E | Cardiovascular disease | Low-density lipoprotein cholesterol | Risk factors | cardiovascular disease | risk factors | adrenal steroid hormones | low-density lipoprotein cholesterol | vitamin E | gonadal hormones | LDL-CHOLESTEROL | CARDIAC & CARDIOVASCULAR SYSTEMS | COENZYME-A REDUCTASE | TESTICULAR FUNCTION | CORTICOSTEROID PRODUCTION | HOMOZYGOUS HYPOBETALIPOPROTEINEMIA | ADRENAL STEROIDOGENESIS | HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA | PERIPHERAL VASCULAR DISEASE | HIGH-DOSE SIMVASTATIN | RED-BLOOD-CELLS | HEMATOLOGY | DENSITY-LIPOPROTEIN RECEPTOR | Proprotein Convertases - antagonists & inhibitors | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Gonadal Steroid Hormones - blood | Hypercholesterolemia - drug therapy | Time Factors | Hypercholesterolemia - enzymology | Cholesterol, LDL - blood | Female | Hydrocortisone - blood | Adrenocorticotropic Hormone - blood | Hypercholesterolemia - blood | Double-Blind Method | Proprotein Convertases - metabolism | Vitamin E - blood | Treatment Outcome | Biomarkers - blood | Anticholesteremic Agents - adverse effects | Anticholesteremic Agents - therapeutic use | Hypercholesterolemia - diagnosis | Aged | Serine Endopeptidases - metabolism | Proprotein Convertase 9
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