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The New England Journal of Medicine, ISSN 0028-4793, 01/2011, Volume 364, Issue 3, pp. 215 - 225
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 34, pp. 15140 - 15144
Between the genetic extremes of rare monogenic and common polygenic diseases lie diverse oligogenic disorders involving mutations in more than one locus in... 
Deficiency diseases | Sex hormones | Nervous system diseases | Disease models | Medical genetics | Genetic diseases | Genetic mutation | Kallmann syndrome | Human genetics | Hypogonadism | Rare variant | Digenic | Idiopathic hypogonadotropic hypogonadism | FGFR1 | idiopathic hypogonadotropic hypogonadism | GPR54 | MULTIDISCIPLINARY SCIENCES | CLINICAL HETEROGENEITY | MISSENSE MUTATIONS | PUBERTY | digenic | GENE | BARDET-BIEDL-SYNDROME | LINKED KALLMANN-SYNDROME | FIBROBLAST-GROWTH-FACTOR-RECEPTOR-1 | GNRH RECEPTOR | rare variant | Receptors, LHRH - genetics | Humans | Male | Gene Regulatory Networks | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Case-Control Studies | Receptors, Peptide - genetics | Genetic Variation | DNA Mutational Analysis | Female | Neuropeptides - genetics | Fibroblast Growth Factor 8 - genetics | Kallmann Syndrome - genetics | Extracellular Matrix Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Hypogonadism - genetics | Homozygote | Phenotype | Pedigree | Gastrointestinal Hormones - genetics | Heterozygote | Models, Genetic | Receptors, G-Protein-Coupled - genetics | Mutation | Receptors, Kisspeptin-1 | Gonadotropin-Releasing Hormone - deficiency | Cohort Studies | Multifactorial diseases | Genetic aspects | Hormones | Gonadotropin | Health aspects | Pathogens | Genetics | Genetic disorders | Pathogenesis | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2017, Volume 114, Issue 9, pp. 2413 - 2418
Mammalian reproductive function depends upon a neuroendocrine circuit that evokes the pulsatile release of gonadotropin hormones (luteinizing hormone and... 
Agouti-related peptide | Kisspeptin | Fertility | Leptin | Gonadotrophin-releasing hormone | ACTIVATION | kisspeptin | MULTIDISCIPLINARY SCIENCES | fertility | PROOPIOMELANOCORTIN NEURONS | MOUSE | PULSATILE LUTEINIZING-HORMONE | ARCUATE NUCLEUS | leptin | NEUROPEPTIDE-Y | AGOUTI-RELATED PROTEIN | gonadotrophin-releasing hormone | agouti-related peptide | GENE-EXPRESSION | OB-OB | MICE | Estrous Cycle - physiology | Leptin - metabolism | Male | Neurons - cytology | Optogenetics | Luteinizing Hormone - metabolism | Clozapine - pharmacology | Fertility - genetics | Kisspeptins - genetics | Fertility - drug effects | Female | Agouti-Related Protein - deficiency | Neurons - metabolism | Hypothalamus - drug effects | Neurons - drug effects | Starvation - genetics | Luteinizing Hormone - genetics | Circadian Clocks - drug effects | Signal Transduction | Gonadotropin-Releasing Hormone - genetics | Gene Expression Regulation | Reproduction - genetics | Mice, Transgenic | Leptin - genetics | Clozapine - analogs & derivatives | Kisspeptins - metabolism | Estrous Cycle - drug effects | Stereotaxic Techniques | Reproduction - drug effects | Animals | Hypothalamus - metabolism | Agouti-Related Protein - genetics | Gonadotropin-Releasing Hormone - metabolism | Mice | Circadian Clocks - physiology | Reproduction | Neurosciences | Hormones | Peptides | Neurons | Index Medicus | Biological Sciences
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2008, Volume 118, Issue 8, pp. 2822 - 2831
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2009, Volume 106, Issue 28, pp. 11703 - 11708
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 03/2016, Volume 6, Issue 1, pp. 23790 - 23790
Anti-Mullerian hormone (AMH) contributes to male sexual differentiation and acts on gonads of both sexes. Identification of AMH receptivity in both pituitary... 
CELLS | DIFFERENT AGES | PULSE-FREQUENCY | RIBONUCLEIC-ACID EXPRESSION | MULTIDISCIPLINARY SCIENCES | II RECEPTOR | INHIBITING SUBSTANCE | GENE-EXPRESSION | BETA-SUBUNIT | LUTEINIZING-HORMONE | Receptors, Transforming Growth Factor beta - genetics | Gonadotrophs - cytology | Rats, Wistar | Activins - metabolism | Male | Luteinizing Hormone - metabolism | RNA, Messenger - metabolism | Receptors, Peptide - genetics | Anti-Mullerian Hormone - genetics | Pituitary Gland, Anterior - growth & development | Gene Expression Regulation, Developmental | Pituitary Gland, Anterior - secretion | Bone Morphogenetic Protein 2 - metabolism | Female | Follicle Stimulating Hormone - genetics | Gonadotrophs - secretion | Sexual Maturation | Animals, Newborn | Bone Morphogenetic Protein 2 - genetics | Cell Line | Follicle Stimulating Hormone - metabolism | Luteinizing Hormone - genetics | Signal Transduction | Gonadotropin-Releasing Hormone - genetics | RNA, Messenger - genetics | Rats | Smad Proteins - genetics | Sex Characteristics | Animals | Hypothalamus - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Pituitary Gland, Anterior - cytology | Gonadotropin-Releasing Hormone - metabolism | Activins - genetics | Anti-Mullerian Hormone - metabolism | Smad Proteins - metabolism | Receptors, Peptide - metabolism | Puberty | Smad protein | Follicle-stimulating hormone | Bone morphogenetic protein 2 | Transcription | Sex differentiation | Secretion | Pituitary (anterior) | Gonadotropins | Dimorphism | Hypothalamus | Gene expression | Pituitary | Luteinizing hormone | Gonadotropin-releasing hormone | Sexual dimorphism | Females | Activin | Gonads | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 12/2009, Volume 150, Issue 12, pp. 5549 - 5556
Journal Article
Journal of Neuroendocrinology, ISSN 0953-8194, 02/2013, Volume 25, Issue 2, pp. 206 - 215
Normal anterior pituitary function is essential for fertility. Release from the gland of the reproductive hormones luteinising hormone and follicle‐stimulating... 
pituitary | gonadotrophins | receptor | RNA | bioinformatics | reproduction | Reproduction | Gonadotrophins | Bioinformatics | SiRNA | Pituitary | GnRH receptor | GONADOTROPIN-RELEASING-HORMONE | RECEPTOR | siRNA | CELL-LINES | NEUROSCIENCES | MESSENGER-RNA LEVELS | LH-BETA | RAT PITUITARY | IN-VITRO | GENE | ENDOCRINOLOGY & METABOLISM | SECRETION | GNRH | Pituitary Hormones - isolation & purification | Peptide Hormones - pharmacology | Fertility Agents - isolation & purification | Hypothalamic Hormones - isolation & purification | Fertility Agents - chemistry | Molecular Sequence Data | Reproduction - physiology | Male | Peptide Hormones - genetics | Dose-Response Relationship, Drug | Peptide Hormones - metabolism | Cloning, Molecular | Pituitary Hormones - metabolism | Female | Pituitary Hormones - pharmacology | Amino Acid Sequence | Peptide Hormones - isolation & purification | Luteinizing Hormone - blood | Gonadotropin-Releasing Hormone - genetics | Cells, Cultured | Rats | Reproduction - genetics | Rats, Sprague-Dawley | Hypothalamic Hormones - pharmacology | Reproduction - drug effects | Sequence Homology, Amino Acid | Fertility Agents - pharmacology | Animals | Fertility Agents - metabolism | Hypothalamic Hormones - metabolism | Gonadotropin-Releasing Hormone - metabolism | Pituitary Hormones - genetics | Hypothalamic Hormones - genetics | Peptides | Neurohormones | Follicle-stimulating hormone | Index Medicus | Fertility | Secretion | Pituitary (anterior) | Gonadotropin-releasing hormone | Hormones | Hypothalamus | Vesicle fusion
Journal Article
Journal Article