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index medicus (203) 203
animals (194) 194
developmental biology (128) 128
goosecoid protein (110) 110
gene expression regulation, developmental (109) 109
transcription factors (93) 93
homeodomain proteins - genetics (92) 92
repressor proteins (85) 85
homeodomain proteins - metabolism (75) 75
molecular sequence data (69) 69
amino acid sequence (60) 60
goosecoid (59) 59
mice (58) 58
xenopus (58) 58
cell biology (56) 56
in situ hybridization (56) 56
signal transduction (51) 51
xenopus proteins (47) 47
expression (46) 46
zebrafish proteins (46) 46
homeobox gene (44) 44
humans (43) 43
zebrafish (42) 42
mesoderm (41) 41
zebrafish - embryology (41) 41
dna-binding proteins - genetics (40) 40
gene expression (40) 40
gastrulation (38) 38
goosecoid protein - genetics (37) 37
organizer (37) 37
base sequence (36) 36
transcription factors - genetics (36) 36
proteins - genetics (35) 35
research (35) 35
mesoderm induction (34) 34
biochemistry & molecular biology (33) 33
embryos (33) 33
female (32) 32
goosecoid protein - metabolism (32) 32
homeodomain proteins (32) 32
mesoderm - metabolism (31) 31
promoter regions, genetic (31) 31
sequence homology, amino acid (30) 30
gene (29) 29
mutation (29) 29
spemann organizer (27) 27
spemanns organizer (27) 27
embryonic structures (26) 26
genes (26) 26
goosecoid expression (26) 26
transcription factors - metabolism (26) 26
xenopus laevis - embryology (26) 26
beta-catenin (25) 25
dna-binding proteins - metabolism (25) 25
goosecoid gene (25) 25
mouse (25) 25
genetic aspects (24) 24
activin (23) 23
animal structures (23) 23
rna, messenger - metabolism (23) 23
transcription, genetic (23) 23
xenopus - embryology (23) 23
body patterning (22) 22
embryo, nonmammalian - metabolism (22) 22
time factors (22) 22
cells (21) 21
repressor proteins - genetics (21) 21
transforming growth factor beta - metabolism (21) 21
zebrafish - genetics (21) 21
cloning, molecular (20) 20
intercellular signaling peptides and proteins (20) 20
molecular biology (20) 20
protein binding (20) 20
t-box domain proteins - genetics (20) 20
wnt proteins (20) 20
homeodomain proteins - physiology (19) 19
induction (19) 19
morphogenesis (19) 19
multidisciplinary sciences (19) 19
phenotype (19) 19
transcription (19) 19
xenopus laevis - genetics (19) 19
activins (18) 18
cell differentiation (18) 18
bone morphogenetic protein 4 (17) 17
bone morphogenetic protein-4 (17) 17
bone morphogenetic proteins - metabolism (17) 17
physiological aspects (17) 17
reverse transcriptase polymerase chain reaction (17) 17
t-box domain proteins (17) 17
transforming growth factor beta - genetics (17) 17
body patterning - genetics (16) 16
cell line (16) 16
embryonic development (16) 16
gastrula - metabolism (16) 16
microinjections (16) 16
neural induction (16) 16
nodal protein (16) 16
proteins - metabolism (16) 16
repressor proteins - metabolism (16) 16
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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2007, Volume 104, Issue 24, pp. 10069 - 10074
The metastatic spread of epithelial cancer cells from the primary tumor to distant organs mimics the cell migrations that occur during embryogenesis. Using... 
Tumor cell line | Transcription factors | Lungs | Genetic vectors | Epithelial cells | Cell lines | Cadherins | Breast cancer | Tumors | Nodules | Twist and snail | Epithelial-mesenchymal transition | Embryogenesis | TUMOR PROGRESSION | MULTIDISCIPLINARY SCIENCES | E-CADHERIN EXPRESSION | TRANSCRIPTION FACTOR SNAIL | EPITHELIAL-MESENCHYMAL TRANSITIONS | ONCOGENIC TRANSFORMATION | SLUG | GROWTH-FACTOR-BETA | CELL PLASTICITY | INVASION | embryogenesis | Twist and Snail | GENE-EXPRESSION | epithelial-mesenchymal transition | Humans | Transforming Growth Factor beta1 - metabolism | Gene Expression Regulation, Neoplastic | Mesoderm | Forkhead Transcription Factors - physiology | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | RNA, Messenger - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Goosecoid Protein - genetics | Goosecoid Protein - metabolism | Neoplasm Metastasis | Forkhead Transcription Factors - metabolism | Mammary Neoplasms, Experimental - pathology | Female | Snail Family Transcription Factors | Carcinoma, Basal Cell - pathology | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Twist-Related Protein 1 - metabolism | Cell Line, Transformed | Cell Transformation, Viral | Genetic aspects | Metastasis | Research | Human embryo | Oncology | Embryology | Gene expression | Cells | Index Medicus | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, pp. e21796 - e21796
Background: Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific role of AP-1 in activin signaling... 
TGF-BETA | FGF | BIOLOGY | FIBROBLAST-GROWTH-FACTOR | CELL-PROLIFERATION | BMP-4 | SPECIFICATION | EARLY XENOPUS DEVELOPMENT | TUMORIGENESIS | EMBRYOS | MESODERM INDUCTION | Embryo, Nonmammalian - cytology | Immunoprecipitation | Luciferases - metabolism | Xenopus Proteins - genetics | Transcription Factor AP-1 - genetics | Bone Morphogenetic Protein 4 - genetics | Protein Multimerization | Transcriptional Activation | Embryo, Nonmammalian - metabolism | Glycoproteins - metabolism | Activins - metabolism | Smad3 Protein - metabolism | Bone Morphogenetic Protein 4 - metabolism | Transcription Factor AP-1 - metabolism | Goosecoid Protein - genetics | Goosecoid Protein - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Smad3 Protein - genetics | In Situ Hybridization | Chromatin Immunoprecipitation | Glycoproteins - genetics | Promoter Regions, Genetic | Signal Transduction | Proto-Oncogene Proteins c-jun - genetics | RNA, Messenger - genetics | Xenopus laevis | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Proto-Oncogene Proteins c-fos - metabolism | Reverse Transcriptase Polymerase Chain Reaction | T-Box Domain Proteins - genetics | Blotting, Western | T-Box Domain Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Organizers, Embryonic - metabolism | Protein Binding | Proto-Oncogene Proteins c-fos - genetics | Xenopus Proteins - metabolism | Activins - genetics | Physiological aspects | Gene expression | Bone morphogenetic proteins | Fibroblast growth factor | Transcription factors | Transcription | Genes | Gene regulation | Biochemistry | Smad3 protein | Reptiles & amphibians | Proteins | Embryogenesis | Physiology | Growth factors | c-Fos protein | Bone morphogenetic protein 4 | Cytokines | Activator protein 1 | c-Jun protein | Chordin | Noggin protein | Embryos | Mutants | Embryonic growth stage | Medicine | Signaling | Stem cells | Activin | Binding sites | Index Medicus
Journal Article
Mechanisms of Development, ISSN 0925-4773, 09/2012, Volume 129, Issue 9-12, pp. 263 - 274
Journal Article
Nature, ISSN 0028-0836, 10/2003, Volume 425, Issue 6961, pp. 917 - 925
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2016, Volume 291, Issue 7, pp. 3333 - 3345
Inscuteable (Insc) regulates cell fate decisions in several types of stem cells. Although it is recognized that the expression levels of mouse INSC govern the... 
RNA-POLYMERASE-II | cell differentiation | gene transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | cell division | SPINDLE ORIENTATION | SELF-RENEWAL | GANGLION MOTHER CELLS | embryonic stem cell | MAINTAINS PLURIPOTENCY | DROSOPHILA ASYMMETRIC DIVISIONS | promoter | CENTRAL-NERVOUS-SYSTEM | NF-KAPPA-B | TRANSCRIPTION FACTOR | ES CELLS | Proto-Oncogene Proteins c-rel - metabolism | Mouse Embryonic Stem Cells - cytology | Mesoderm - cytology | Mouse Embryonic Stem Cells - metabolism | Goosecoid Protein - genetics | Cell Cycle Proteins - antagonists & inhibitors | Goosecoid Protein - metabolism | Chromatin Immunoprecipitation | RNA Interference | Endoderm - cytology | Gene Expression Regulation, Developmental | Cell Cycle Proteins - genetics | Cell Differentiation | Genes, Reporter | Proto-Oncogene Proteins c-rel - antagonists & inhibitors | Recombinant Proteins - metabolism | Cell Line | Promoter Regions, Genetic | Cell Cycle Proteins - metabolism | Recombinant Proteins - chemistry | Cell Cycle Proteins - agonists | Endoderm - metabolism | Animals | Proto-Oncogene Proteins c-rel - genetics | Regulatory Elements, Transcriptional | Transcription Initiation Site | Luminescent Proteins - genetics | Mesoderm - metabolism | Mice | RNA, Small Interfering | Luminescent Proteins - metabolism | Index Medicus | Gene Regulation
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 44, pp. E6840 - E6848
Neurons of the Statoacoustic Ganglion (SAG), which innervate the inner ear, originate as neuroblasts in the floor of the otic vesicle and subsequently... 
EMT | Neurogenesis | Gsc | Inner ear | Pax2 | WILD-TYPE | CRANIAL SENSORY GANGLIA | ZEBRAFISH | MULTIDISCIPLINARY SCIENCES | MUTANT EMBRYOS | HOMEOBOX GENES | HAIR-CELLS | TO-MESENCHYMAL TRANSITION | PLACODE INDUCTION | neurogenesis | INNER-EAR MORPHOGENESIS | inner ear | NEURAL CREST | Immunohistochemistry | Up-Regulation | Ganglia, Parasympathetic - growth & development | PAX2 Transcription Factor - metabolism | Cadherins - metabolism | Epithelial-Mesenchymal Transition - physiology | Genes, Overlapping | Ganglia, Parasympathetic - metabolism | Goosecoid Protein - genetics | Goosecoid Protein - metabolism | Neurogenesis - genetics | Cell Differentiation - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Ganglia, Parasympathetic - pathology | Vestibulocochlear Nerve - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Gastrulation | Signal Transduction | Zebrafish Proteins - metabolism | Nerve Tissue Proteins - genetics | Neural Stem Cells - pathology | Vestibulocochlear Nerve - growth & development | Zebrafish - genetics | Organizers, Embryonic - pathology | Nerve Tissue Proteins - metabolism | Ear, Inner - metabolism | Animals | Neurogenesis - physiology | Zebrafish - metabolism | Zebrafish Proteins - genetics | Neural Stem Cells - metabolism | Labyrinth (Ear) | Physiological aspects | Physiological research | Cell organelles | Genetic aspects | Research | Brain | Vertebrates | Zebrafish | Gene expression | Cells | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Nature Cell Biology, ISSN 1465-7392, 01/2011, Volume 13, Issue 1, pp. 59 - 65
Journal Article
Journal Article
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2011, Volume 21, Issue 6, pp. 911 - 921
In embryonic stem cells (ESCs), Wnt-responsive development-related genes are silenced to maintain pluripotency and their expression is activated during... 
组蛋白修饰 | 胚胎干细胞 | 分化过程 | 组蛋白脱乙酰化 | Wnt信号通路 | 转录抑制 | 蛋白磷酸酶 | 靶基因 | protein phosphatase 4 complex | Wnt signaling | differentiation | embryonic stem cell | HDAC1 | Smek | COMPLEX | ACTIVATION | CARDIOVASCULAR PROGENITORS | PROLIFERATION | CELL BIOLOGY | MESODERM | CATENIN PATHWAY | REGULATORY CIRCUITRY | CARDIOMYOCYTE DIFFERENTIATION | CONSERVED PROTEIN | EXPRESSION | Immunoprecipitation | Homeodomain Proteins - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Alkaline Phosphatase - metabolism | Fetal Proteins - metabolism | Wnt Proteins - metabolism | Goosecoid Protein - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Goosecoid Protein - metabolism | Cell Differentiation - genetics | Multiprotein Complexes - metabolism | Cell Nucleus - metabolism | Wnt Proteins - genetics | RNA Interference | Transcription, Genetic | Acetylation | Promoter Regions, Genetic | Down-Regulation | Cells, Cultured | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-2 - metabolism | T-Box Domain Proteins - genetics | beta Catenin - metabolism | Homeodomain Proteins - genetics | T-Box Domain Proteins - metabolism | beta Catenin - genetics | Pluripotent Stem Cells - metabolism | Animals | Phosphoprotein Phosphatases - genetics | Protein Binding | LIM-Homeodomain Proteins | Fetal Proteins - genetics | Mice | Transcription Factors | Histones - metabolism | Histone Deacetylase 1 - metabolism | Index Medicus | Original
Journal Article