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1. Full Text Initial experience with identifying high-grade prostate cancer using diffusion-weighted MR imaging (DWI) in patients with a Gleason score
by Somford, D.M and Hambrock, T and Hulsbergen- van de Kaa, C.A and Futterer, J.J and Oort, I.M. van and Basten, J.P. van and Karthaus, H.F.M and Witjes, J.A and Barentsz, J.O
Investigative Radiology, ISSN 0020-9996, 2012, Volume 47, Issue 3, pp. 153 - 158
INTRODUCTION: Diffusion-weighted magnetic resonance (MR) imaging (DWI) might be able to fulfill the need to accurately identify high-grade prostate carcinoma,... 
magnetic resonance imaging | COEFFICIENT VALUES | INSIGNIFICANT | TISSUE | TUMOR | PATHOLOGICAL FINDINGS | TRANSITION | apparent diffusion coefficient | Gleason | HISTOLOGIC GRADE | ACTIVE SURVEILLANCE | prostatic neoplasms | biopsy | AGGRESSIVENESS | NEEDLE-BIOPSY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Prostatic Neoplasms - pathology | Time Factors | Biopsy | Diffusion Magnetic Resonance Imaging - instrumentation | Humans | Transurethral Resection of Prostate - methods | Statistics, Nonparametric | Male | Retrospective Studies | Transurethral Resection of Prostate - instrumentation | Neoplasm Grading - instrumentation | Prostatic Neoplasms - diagnosis
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2. Full Text Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?
by Jennifer R. Stark and Sven Perner and Meir J. Stampfer and Jennifer A. Sinnott and Stephen Finn and Anna S. Eisenstein and Jing Ma and Michelangelo Fiorentino and Tobias Kurth and Massimo Loda and Edward L. Giovannucci and Mark A. Rubin and Lorelei A. Mucci
Journal of Clinical Oncology, ISSN 0732-183X, 07/2009, Volume 27, Issue 21, pp. 3459 - 3464
Purpose Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score... 
GRADING SYSTEM | BETA-CAROTENE | ONCOLOGY | CARDIOVASCULAR-DISEASE | RANDOMIZED-TRIAL | RADICAL PROSTATECTOMY | PROGNOSTIC-SIGNIFICANCE | NEEDLE-BIOPSY | PHYSICIANS HEALTH | PROGRESSION | RADIATION-THERAPY | Prostatic Neoplasms - pathology | Prognosis | Follow-Up Studies | Prostatic Neoplasms - surgery | Neoplasm Invasiveness | Humans | Male | Treatment Outcome | Prostatic Neoplasms - mortality | Time Factors | Biopsy | Prostatectomy | Neoplasm Staging | Postoperative Complications | Prostatic Neoplasms - drug therapy | Original Reports | Guc1 | Guc2
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3. Full Text Cochrane Qualitative and Implementation Methods Group guidance series—paper 3: methods for assessing methodological limitations, data extraction and synthesis, and confidence in synthesized qualitative findings
by Noyes, Jane and Booth, Andrew and Flemming, Kate and Garside, Ruth and Harden, Angela and Lewin, Simon and Pantoja, Tomas and Hannes, Karin and Cargo, Margaret and Thomas, James
Journal of Clinical Epidemiology, ISSN 0895-4356, 05/2018, Volume 97, pp. 49 - 58
The Cochrane Qualitative and Implementation Methods Group develops and publishes guidance on the synthesis of qualitative and mixed-method implementation... 
Qualitative research | Systematic review | GRADE CERQual | Qualitative evidence synthesis | Cochrane | Methodological limitations | SYSTEMATIC REVIEWS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | GUIDELINES | HEALTH CARE SCIENCES & SERVICES | META-ETHNOGRAPHY | EXPERIENCE | Decision Making | Evidence-Based Medicine - standards | Data Accuracy | Humans | Systematic Reviews as Topic | Data Analysis | Qualitative Research | Biomedical Research - standards | Intervention | Reflexivity | Decision making | Data processing | Research | Grey literature | Studies | Hypotheses | Researchers | Synthesis | Reviews | Quality | Qualitative analysis | Methods
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4. Full Text Population-based study of grade progression in patients who harboured Gleason 3 + 3
by Sampurno, Fanny and Earnest, Arul and Millar, Jeremy and Frydenberg, Mark and Murphy, Declan and Delprado, Warwick and Evans, Sue
World Journal of Urology, ISSN 0724-4983, 11/2017, Volume 35, Issue 11, pp. 1689 - 1699
This study aimed to evaluate (1) the time interval between a decision to commence on active surveillance (AS) and grade progression in community practice; (2)... 
Grade group | Nephrology | Active surveillance | Gleason | Medicine & Public Health | Population-based clinical registry | Oncology | Prostate cancer | Urology | DIAGNOSIS | PSA VELOCITY | STAGE | TIME | PREDICTION | PROSTATE-CANCER | MEN | UROLOGY & NEPHROLOGY | IMPROVES | BIOPSIES | Multivariate Analysis | Prostatic Neoplasms - pathology | Humans | Middle Aged | Victoria | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Disease Progression | Prostate-Specific Antigen - blood | Prostatic Neoplasms - therapy | Neoplasm Grading | Prostatic Neoplasms - blood | Registries | Watchful Waiting | Aged | Kallikreins - blood | Neoplasm Staging | Medicine, Experimental | Medical research | Development and progression | Analysis | Surveillance | Biopsy | Population studies | Velocity | Prostate | Tumors
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5. Full Text Evaluation of a Minimally Invasive Cell Sampling Device Coupled with Assessment of Trefoil Factor 3 Expression for Diagnosing Barrett's Esophagus: A Multi-Center Case–Control Study
by Ross-Innes, Caryn S and Debiram-Beecham, Irene and O'Donovan, Maria and Walker, Elaine and Varghese, Sibu and Lao-Sirieix, Pierre and Lovat, Laurence and Griffin, Michael and Ragunath, Krish and Haidry, Rehan and Sami, Sarmed S and Kaye, Philip and Novelli, Marco and Disep, Babett and Ostler, Richard and Aigret, Benoit and North, Bernard V and Bhandari, Pradeep and Haycock, Adam and Morris, Danielle and Attwood, Stephen and Dhar, Anjan and Rees, Colin and Rutter, Matthew D. D and Sasieni, Peter D and Fitzgerald, Rebecca C and BEST2 Study Grp and BEST2 Study Group and on behalf of the BEST2 Study Group
PLoS Medicine, ISSN 1549-1277, 01/2015, Volume 12, Issue 1, pp. 1 - 19
Background Barrett's esophagus (BE) is a commonly undiagnosed condition that predisposes to esophageal adenocarcinoma. Routine endoscopic screening for BE is... 
ENDOSCOPIC SURVEILLANCE | MEDICINE, GENERAL & INTERNAL | GENERAL-POPULATION | REFLUX SYMPTOMS | GRADE DYSPLASIA | MANAGEMENT | COLORECTAL-CANCER | ADENOCARCINOMA | DISEASE | RISK | RADIOFREQUENCY ABLATION | Biomarkers - metabolism | Barrett Esophagus - metabolism | Humans | Middle Aged | Biomarkers - analysis | Male | Case-Control Studies | Endoscopy, Digestive System - instrumentation | Barrett Esophagus - pathology | Peptides - metabolism | Sensitivity and Specificity | Trefoil Factor-3 | Barrett Esophagus - diagnosis | Female | Aged | Peptides - analysis | Gastroesophageal reflux | Studies | Medical research | Health risk assessment
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6. Full Text Nationwide prevalence of lymph node metastases in Gleason score 3+3=6 prostate cancer
by Liu, Jen-Jane and Lichtensztajn, Daphne Y and Gomez, Scarlett Lin and Sieh, Weiva and Chung, Benjamin I and Cheng, Iona and Brooks, James D
Pathology, ISSN 0031-3025, 06/2014, Volume 46, Issue 4, pp. 306 - 310
Based on revisions of Gleason scoring in 2005, it has been reported that nodal metastases at radical prostatectomy in Gleason 3+3=6 (GS6) prostate cancer are... 
Gleason score | SEER Program | prostatic neoplasms | lymph node metastasis | Lymph node metastasis | Prostatic neoplasms | SEER program | IMPACT | ACTIVE SURVEILLANCE | ADENOCARCINOMA | GRADE | PATHOLOGY | CARCINOMA | REPRODUCIBILITY | Prostatic Neoplasms - pathology | United States - epidemiology | Adenocarcinoma - pathology | Prevalence | Humans | Middle Aged | Male | Prostatic Neoplasms - epidemiology | Neoplasm Grading | Lymphatic Metastasis - pathology | Adult | Aged
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7. Full Text Child proportional scaling: Is 1/3 = 2/6 = 3/9 = 4/12?
by Boyer, Ty W and Levine, Susan C
Journal of Experimental Child Psychology, ISSN 0022-0965, 2012, Volume 111, Issue 3, pp. 516 - 533
â–º Children completed two variants of a proportional equivalence reasoning task. â–º Performance varied with scale factor. â–º Proportional scaling bears cognitive... 
Relative scaling | Mathematical development | Mental transformation | Spatial cognition | Proportional reasoning | Numerical reasoning | METAANALYSIS | PSYCHOLOGY, DEVELOPMENTAL | PSYCHOLOGY, EXPERIMENTAL | PROBABILITY | PRESCHOOLERS | INFANTS | ABILITY | CONSTRUCTION | SEX-DIFFERENCES | MENTAL ROTATION | YOUNG-CHILDREN | NUMBER SENSE | Grade 1 | Grade 2 | Grade 3 | Task Analysis | Grade 4 | Mathematical Concepts | Kindergarten | Experimental Psychology | Measures (Individuals) | Scaffolding (Teaching Technique) | Scaling | Children | Error Patterns | Choice Behavior | Humans | Female | Male | Child Development | Factor Analysis, Statistical | Mathematics | Intuition | Comprehension | Child | Judgment | Cognition
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8. Full Text Experimental investigation of lubricant oil on a 3 kW organic Rankine cycle (ORC) using R123
by Feng, Yong-qiang and Hung, Tzu-Chen and He, Ya-Ling and Wang, Qian and Chen, Shih-Chi and Wu, Shang-Lun and Lin, Chih-Hung
Energy Conversion and Management, ISSN 0196-8904, 02/2019, Volume 182, pp. 340 - 350
The lubricant oil can prevent the leakages and reduce the expander friction losses, but blend with the pure working fluid because of the absence of oil... 
Degree of superheating | Lubricant oil ratio | Thermal efficiency | System generating efficiency | Organic Rankine cycle (ORC) | DESIGN | ENERGY & FUELS | PERFORMANCE | GRADE WASTE HEAT | THERMOECONOMIC MULTIOBJECTIVE OPTIMIZATION | RECOVERY | MECHANICS | THERMODYNAMICS | OPERATION | PISTON | POWER-GENERATION | R245FA | DRIVE SCROLL EXPANDER | Lubrication and lubricants | Electric properties | Superheating | Thermodynamic efficiency | Lubricants | Flow rates | Separators | Heat recovery | Friction reduction | Heat | Oil | Mass flow rate | Efficiency | Electric power | Rankine cycle | Working fluids | Power efficiency
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9. Full Text The impact of re-transurethral resection on clinical outcomes in a large multicentre cohort of patients with T1 high-grade/Grade 3 bladder cancer treated with bacille Calmette-Guerin
by Gontero, P and Sylvester, R and Pisano, F and Joniau, S and Oderda, M and Serretta, V and Larre, S and Stasi, S. Di and Rhijn, B. Van and Witjes, A.J and Grotenhuis, A.J and Colombo, R and Briganti, A and Babjuk, M and Soukup, V and Malmstrom, P.U and Irani, J and Malats, N and Baniel, J and Mano, R and Cai, T and Cha, E.K and Ardelt, P and Vakarakis, J and Bartoletti, R and Dalbagni, G and Shariat, S.F and Xylinas, E and Karnes, R.J and Palou, J and Medicinska fakulteten and Urologkirurgi and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för kirurgiska vetenskaper
BJU International, ISSN 1464-4096, 2016, Volume 118, Issue 1, pp. 44 - 52
OBJECTIVES: To determine if a re-transurethral resection (TUR), in the presence or absence of muscle at the first TUR in patients with T1-high grade (HG)/Grade... 
TUR | recurrence | re | bladder cancer | progression | high grade | T1G3 | re-TUR | PROGRESSION RATE | INVASIVE UROTHELIAL CARCINOMA | UROLOGY & NEPHROLOGY | RISK | UPDATE | Reoperation | Humans | Middle Aged | Male | Treatment Outcome | Urinary Bladder Neoplasms - drug therapy | Urinary Bladder Neoplasms - surgery | Neoplasm Grading | Urethra | Urinary Bladder Neoplasms - pathology | Female | Aged | Retrospective Studies | BCG Vaccine - therapeutic use | Neoplasm Staging | Adjuvants, Immunologic - therapeutic use | Cystectomy - methods | Clinical Medicine | Urologi och njurmedicin | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Urology and Nephrology | bladder cancer; T1G3; high grade; re-TUR; recurrence; progression
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10. Full Text Predictive biomarkers of sensitivity to the phosphatidylinositol 3′ kinase inhibitor GDC-0941 in breast cancer preclinical models
by O'Brien, Carol and Wallin, Jeffrey J and Sampath, Deepak and GuhaThakurta, Debraj and Savage, Heidi and Punnoose, Elizabeth A and Guan, Jane and Berry, Leanne and Prior, Wei Wei and Amler, Lukas C and Belvin, Marcia and Friedman, Lori S and Lackner, Mark R
Clinical Cancer Research, ISSN 1078-0432, 07/2010, Volume 16, Issue 14, pp. 3670 - 3683
Purpose: The class I phosphatidylinositol 3' kinase (PI3K) plays a major role in proliferation and survival in a wide variety of human cancers. A key factor in... 
EXPRESSION PATTERNS | MEK | HISTOLOGIC GRADE | PIK3CA MUTATIONS | GENE | PI3K | ONCOLOGY | PATHWAY | HIGH-FREQUENCY | AKT | VIVO ANTITUMOR-ACTIVITY | Neoplasm Transplantation | Predictive Value of Tests | Oligonucleotide Array Sequence Analysis | Receptor, ErbB-2 - genetics | Apoptosis - drug effects | Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Humans | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Sensitivity and Specificity | Biomarkers, Tumor - metabolism | Female | Receptor, ErbB-2 - antagonists & inhibitors | Biomarkers, Tumor - antagonists & inhibitors | Phosphatidylinositol 3-Kinase - metabolism | Disease Models, Animal | Mammary Neoplasms, Experimental - drug therapy | Cell Survival - drug effects | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Indazoles - pharmacology | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Phosphatidylinositol 3-Kinase - genetics | Cell Line, Tumor | Biomarkers, Tumor - genetics | Mice | Mutation | Cell Cycle - drug effects
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11. Full Text Clinical significance of prospectively assigned Gleason tertiary pattern 4 in contemporary Gleason score 3+3=6 prostate cancer
by Doshi, Chirag and Vacchio, Michael and Attwood, Kristopher and Murekeyisoni, Christine and Mehedint, Diana C and Badkhshan, Shervin and Azabdaftari, Gissou and Sule, Norbert and Guru, Khurshid A and Mohler, James L and Kauffman, Eric C
The Prostate, ISSN 0270-4137, 06/2016, Volume 76, Issue 8, pp. 715 - 721
OBJECTIVE To determine the oncologic impact of prospectively assigned tertiary pattern 4 in contemporary Gleason score (GS) 3+3=6 radical prostatectomy (RP)... 
prostate cancer | radical prostatectomy | biochemical failure | tertiary Gleason pattern | INTERVAL | SYSTEM | BIOCHEMICAL RECURRENCE | FAILURE | SPECIMENS | IMPACT | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | GRADE | PROGNOSTIC-SIGNIFICANCE | CARCINOMA | Prostatic Neoplasms - pathology | Prognosis | Prostatic Neoplasms - surgery | Humans | Middle Aged | Male | Survival Rate | Disease Progression | Prostatic Neoplasms - mortality | Disease-Free Survival | Prostate - pathology | Neoplasm Grading | Prostatectomy | Aged | Retrospective Studies | Databases, Factual | Development and progression | Metastasis | Prostate cancer | Epidemiology
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12. Full Text Should grade 3 endometrioid endometrial carcinoma be considered a type 2 cancer—A clinical and pathological evaluation
by Voss, Martin A and Ganesan, Raji and Ludeman, Linmarie and McCarthy, Keith and Gornall, Robert and Schaller, Gerhard and Wei, Wenbin and Sundar, Sudha
Gynecologic Oncology, ISSN 0090-8258, 2011, Volume 124, Issue 1, pp. 15 - 20
Abstract Objective Endometrial cancer is classified into: Type I estrogen-dependent endometrioid adenocarcinoma, with good prognosis and type 2... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Immunohistochemistry | Endometrial cancer | Uterine papillary serous and clear cell carcinoma | Type I and II | Grade 3 endometrioid | Survival | P53 OVEREXPRESSION | RECEPTOR STATUS | OBSTETRICS & GYNECOLOGY | PATHOGENESIS | ONCOLOGY | MOLECULAR-GENETIC-PATHWAYS | IMMUNOHISTOCHEMICAL ANALYSIS | SEROUS CARCINOMA | PROGNOSTIC-SIGNIFICANCE | MUTATIONS | ASSOCIATION | EXPRESSION | Receptors, Estrogen - metabolism | Carcinoma, Endometrioid - classification | Endometrial Neoplasms - classification | Humans | Middle Aged | Endometrial Neoplasms - metabolism | Receptor, ErbB-2 - metabolism | Tumor Suppressor Protein p53 - metabolism | Survival Rate | Carcinoma, Endometrioid - metabolism | Receptors, Progesterone - metabolism | Neoplasm Grading | Aged, 80 and over | Adult | Endometrial Neoplasms - pathology | Female | Aged | Neoplasm Staging | Carcinoma, Endometrioid - pathology | Carcinoma | Research | Oncology, Experimental | Cancer
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