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1. Full Text Heterogeneity of risk within Gleason 4 + 4, 4 + 5 and 5 + 4 prostate cancer
by Moschini, Marco and Sharma, Vidit and Soligo, Matteo and Psutka, Sarah and Rangel, Laureano and Boorjian, Stephen A and Frank, Igor and Gettman, Matthew T and Thompson, R. Houston and Tollefson, Matthew K and Karnes, R. Jeffrey
Scandinavian Journal of Urology, ISSN 2168-1805, 11/2018, Volume 52, Issue 5-6, pp. 340 - 348
Objects: This study hypothesized that biopsy Gleason score 8 (b.G.S. 8) disease may dilute the substantial poor risk associated with b.G.S. 9 disease,... 
Gleason score | radical prostatectomy | Prostate cancer | high risk | DEFINITION | PATTERN 5 | 2014 INTERNATIONAL SOCIETY | SCORE | GRADE GROUPING SYSTEM | VALIDATION | ISUP CONSENSUS CONFERENCE | BEAM RADIATION-THERAPY | UROLOGY & NEPHROLOGY | STRATIFICATION
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2. Full Text Gleason Score and Lethal Prostate Cancer: Does 3 + 4 = 4 + 3?
by Jennifer R. Stark and Sven Perner and Meir J. Stampfer and Jennifer A. Sinnott and Stephen Finn and Anna S. Eisenstein and Jing Ma and Michelangelo Fiorentino and Tobias Kurth and Massimo Loda and Edward L. Giovannucci and Mark A. Rubin and Lorelei A. Mucci
Journal of Clinical Oncology, ISSN 0732-183X, 07/2009, Volume 27, Issue 21, pp. 3459 - 3464
Purpose Gleason grading is an important predictor of prostate cancer (PCa) outcomes. Studies using surrogate PCa end points suggest outcomes for Gleason score... 
GRADING SYSTEM | BETA-CAROTENE | ONCOLOGY | CARDIOVASCULAR-DISEASE | RANDOMIZED-TRIAL | RADICAL PROSTATECTOMY | PROGNOSTIC-SIGNIFICANCE | NEEDLE-BIOPSY | PHYSICIANS HEALTH | PROGRESSION | RADIATION-THERAPY | Prostatic Neoplasms - pathology | Prognosis | Follow-Up Studies | Prostatic Neoplasms - surgery | Neoplasm Invasiveness | Humans | Male | Treatment Outcome | Prostatic Neoplasms - mortality | Time Factors | Biopsy | Prostatectomy | Neoplasm Staging | Postoperative Complications | Prostatic Neoplasms - drug therapy | Original Reports | Guc1 | Guc2
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3. Full Text GRADE guidelines: 4. Rating the quality of evidence—study limitations (risk of bias)
by Guyatt, Gordon H and Oxman, Andrew D and Vist, Gunn and Kunz, Regina and Brozek, Jan and Alonso-Coello, Pablo and Montori, Victor and Akl, Elie A and Djulbegovic, Ben and Falck-Ytter, Yngve and Norris, Susan L and Williams, John W and Atkins, David and Meerpohl, Joerg and Schünemann, Holger J
Journal of Clinical Epidemiology, ISSN 0895-4356, 2011, Volume 64, Issue 4, pp. 407 - 415
Abstract In the GRADE approach, randomized trials start as high-quality evidence and observational studies as low-quality evidence, but both can be rated down... 
Internal Medicine | risk of bias | concealment | GRADE | quality of evidence | confidence in estimates | blinding | RANDOMIZED CONTROLLED-TRIALS | METAANALYSIS | SAFETY | HEART-FAILURE | PREGNANCY | BENEFIT | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | THERAPY | OUTCOME REPORTING BIAS | HEALTH CARE SCIENCES & SERVICES | EMPIRICAL-EVIDENCE | SPINAL-CORD-INJURY | Evidence-Based Practice | Risk Assessment | Practice Guidelines as Topic - standards | Humans | Publication Bias | Female | Male | Quality Assurance, Health Care - standards | Randomized Controlled Trials as Topic
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4. Full Text Mortality after radical prostatectomy in a matched contemporary cohort in Sweden compared to the Scandinavian Prostate Cancer Group 4 (SPCG‐4) study
by Cazzaniga, Walter and Garmo, Hans and Robinson, David and Holmberg, Lars and Bill‐Axelson, Anna and Stattin, Pär and Medicinska fakulteten and Urologkirurgi and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Endokrinkirurgi and Institutionen för kirurgiska vetenskaper
BJU International, ISSN 1464-4096, 03/2019, Volume 123, Issue 3, pp. 421 - 428
Objective To investigate if results in terms of absolute risk in mature randomised trials are relevant for contemporary decision‐making. To do so, we compared... 
mortality | PCSM | ProstateCancer | Scandinavian Prostate Cancer Group Study Number 4 | Gleason Grade Groups | National Prostate Cancer Register of Sweden | REGISTER | INTERNATIONAL-SOCIETY | BIOPSY | UROLOGY & NEPHROLOGY | ISUP CONSENSUS CONFERENCE | Surgery | Analysis | Mortality | Oncology, Experimental | Research | Health aspects | Prostate cancer | Cancer | Decision making | Migration | Clinical trials | Health risk assessment | Prostate | Clinical Medicine | Urologi och njurmedicin | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Urology and Nephrology
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5. Full Text Diagnosis of “Poorly Formed Glands” Gleason Pattern 4 Prostatic Adenocarcinoma on Needle Biopsy: An Interobserver Reproducibility Study Among Urologic Pathologists With Recommendations
by Zhou, Ming and Li, Jianbo and Cheng, Liang and Egevad, Lars and Deng, Fang-Ming and Kunju, Lakshmi Priya and Magi-Galluzzi, Cristina and Melamed, Jonathan and Mehra, Rohit and Mendrinos, Savvas and Osunkoya, Adeboye O and Paner, Gladell and Shen, Steve S and Tsuzuki, Toyonori and Trpkov, Kiril and Tian, Wei and Yang, Ximing and Shah, Rajal B
The American Journal of Surgical Pathology, ISSN 0147-5185, 10/2015, Volume 39, Issue 10, pp. 1331 - 1339
Accurate recognition of Gleason pattern (GP) 4 prostate carcinoma (PCa) on needle biopsy is critical for patient management and prognostication. “Poorly formed... 
Gleason grade | Prostate needle biopsy | Interobserver reproducibility | Poorly formed glands | Prostate cancer | Gleason pattern 4 | interobserver reproducibility | SURGERY | INTRAOBSERVER REPRODUCIBILITY | ISUP CONSENSUS | CRIBRIFORM PATTERN | RADICAL PROSTATECTOMY | PATHOLOGY | CANCER | poorly formed glands | prostate cancer | prostate needle biopsy | ACTIVE SURVEILLANCE | 2005 INTERNATIONAL-SOCIETY | OF-AMERICAN-PATHOLOGISTS | CONSENSUS STATEMENT | CARCINOMA | Pathology, Clinical - standards | Predictive Value of Tests | Prostatic Neoplasms - pathology | Reproducibility of Results | Adenocarcinoma - pathology | Practice Patterns, Physicians' - standards | Humans | Male | Consensus | Urology - standards | Specialization | Neoplasm Grading | Biopsy, Needle - standards | Cell Differentiation | Observer Variation
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6. Full Text Modified grade 4 osteotomy for kyphosis due to old osteoporotic vertebral compression fractures: Two case reports
by Liu, Feng-Yu and Zhao, Zheng-Qi and Ren, Liang and Gu, Zhen-Fang and Li, Feng and Ding, Wen-Yuan and Sun, Xian-Ze
Medicine, ISSN 0025-7974, 12/2018, Volume 97, Issue 52, p. e13846
Rationale: The kyphosis caused by old osteoporotic vertebral compression fracture usually requires osteotomy to correct it. Various osteotomy techniques have... 
SURGERY | modified grade 4 osteotomy | MEDICINE, GENERAL & INTERNAL | WEDGE OSTEOTOMY | MANAGEMENT | kyphosis | osteoporotic vertebral compression fracture | Humans | Kyphosis - surgery | Osteoporotic Fractures - complications | Fractures, Compression - complications | Spinal Fractures - complications | Female | Male | Aged | Kyphosis - etiology | Osteotomy - methods | Musculoskeletal diseases | Complications and side effects | Kyphosis | Care and treatment | Usage | Osteotomy | Risk factors
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7. Full Text Semiclosure wound therapy plus negative pressure wound therapy for an older patient with grade 4 diabetic foot with concomitant vascular occlusion A case report
by Yan, YF and Li, WF and Song, Y and Yin, P and He, ZZ and Gong, YP and Peng, LL
MEDICINE, ISSN 0025-7974, 11/2019, Volume 98, Issue 44, p. e17786
Rationale: Grade 4 diabetic foot (DF) is a severe infection that causes bone destruction, osteomyelitis, and osteoarticular damage, which, in turn, can lead to... 
ULCERS | MEDICINE, GENERAL & INTERNAL | infection | MULTICENTER | MANAGEMENT | semiclosure of the wound | grade 4 diabetic foot | PREVENTION | older patient | VACUUM-ASSISTED CLOSURE | negative pressure wound therapy | Case studies | Care and treatment | Diabetic foot | Arterial occlusions | Aged patients | Wounds and injuries | Methods
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8. Full Text NAEP 1996 mathematics cross-state data compendium for the grade 4 and grade 8 assessment
: findings from the state assessment in mathematics of the National Assessment of Educational Progress
by Shaughnessy, Catherine A and Nelson, Jennifer E and Norris, Norma A and Educational Testing Service and National Center for Education Statistics and National Assessment of Educational Progress (Project)
1998, The nation's report card, ISBN 9780160494147
United States | Study and teaching | Mathematics
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9. Full Text Correlation of 4′-[methyl-11C]-thiothymidine uptake with human equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in patients with newly diagnosed gliomas
by Takami, Yasukage and Yamamoto, Yuka and Ueno, Masaki and Chiba, Yoichi and Norikane, Takashi and Hatakeyama, Tetsuhiro and Miyake, Keisuke and Toyohara, Jun and Nishiyama, Yoshihiro
Annals of Nuclear Medicine, ISSN 0914-7187, 11/2018, Volume 32, Issue 9, pp. 634 - 641
We examined expressions of human equilibrative nucleoside transporter-1 (hENT1) and thymidine kinase-1 (TK1), the key enzyme in 4′-[methyl-11C]-thiothymidine... 
Medicine & Public Health | Glioma | hENT1 | 4DST | Nuclear Medicine | TK1 | Imaging / Radiology | PET | LUNG-CANCER | GRADE | PROLIFERATION | C-11-4DST | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | HUMAN TUMOR-CELLS | Glioma - diagnosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Equilibrative Nucleoside Transporter 1 - metabolism | Positron-Emission Tomography | Glioma - metabolism | Young Adult | Thymidine - analogs & derivatives | Biological Transport | Thymidine Kinase - metabolism | Female | Aged | Thionucleosides - metabolism | Thymidine - metabolism | Immunohistochemistry | Pets | Enzymes | Care and treatment | Gliomas | Analysis | Nucleosides | Sport-utility vehicles | Brain | Thymidine kinase | Phosphorylation | Nucleoside transporter | Brain tumors | Staining | Thymidine | Patients | Lesions | Transporter | Positron emission tomography | Tumors | Quantitative analysis
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10. Full Text Smoking increased the risk of prostate cancer with grade group ≥ 4 and intraductal carcinoma in a prospective biopsy cohort
by Tang, Bo and Han, Cheng‐Tao and Gan, Hua‐Lei and Zhang, Gui‐Ming and Zhang, Cui‐Zhu and Yang, Wei‐Yi and Shen, Ying and Zhu, Yao and Ye, Ding‐Wei
The Prostate, ISSN 0270-4137, 06/2017, Volume 77, Issue 9, pp. 984 - 989
OBJECTIVE To investigate the association between smoking and different prostate cancer (PCa) pathological subtypes incidence in Chinese men. PATIENTS AND... 
intraductal carcinoma | prostate cancer | grade group | smoking | SYSTEM | METAANALYSIS | PROGNOSIS | ADENOCARCINOMA | TUMORS | MEN | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | SPREAD | RADICAL-PROSTATECTOMY | Biopsy - methods | Prostatic Neoplasms - pathology | Prospective Studies | Carcinoma, Ductal - pathology | Humans | Middle Aged | Risk Factors | Male | Biopsy - statistics & numerical data | Statistics as Topic | China - epidemiology | Incidence | Prostatic Neoplasms - epidemiology | Prostate - pathology | Smoking - epidemiology | Aged | Carcinoma, Ductal - epidemiology | Cigarette smoking | Health risk assessment | Biopsy | Prostate | Prostate cancer | Smoking
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11. Full Text New fluorinated copoly(pyridine ether imide)s derived from 4,4′-oxydianiline, pyromellitic dianhydride and 4-(4-trifluoromethylphenyl)-2,6-bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]pyridine
by Zhou, Yu-Ting and Liu, Xiao-Ling and Wei, Mei-Hong and Song, Cheng and Huang, Zhen-Zhong and Sheng, Shou-Ri
Polymer Bulletin, ISSN 0170-0839, 08/2019, Volume 76, Issue 8, pp. 4139 - 4155
A new aromatic diamine, 4-(4-trifluoromethylphenyl)-2,6-bis[4-(4-amino-2-trifluoromethylphenoxy)phenyl]pyridine (9FPBAPP), was prepared from... 
Copoly(pyridine ether imide)s | Transparency | Ether linkage | Trifluoromethyl pendent group | 4-Trifluoromethylphenyl-2,6-diphenylpyridyl unit | Thermal stability | 4-Trifluoromethylphenyl-2 | SOLUBLE POLYIMIDES | POLYMERS | POLYMER SCIENCE | 6-diphenylpyridyl unit | DIAMINE
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12. Full Text Opinions of Social Studies Teachers Regarding the 4+4+4 Educational System=Sosyal Bilgiler Ögretmenlerinin 4+4+4 Egitim Sistemine Iliskin Görüsleri
by Öztürk, Filiz Zayimoglu
Journal of Social Studies Education Research, ISSN 1309-9108, 2015, Volume 6, Issue 2, p. 31
When the changes in the educational system of this country during the recent years are considered, it is observed that the most fundamental change has been the... 
Teacher Attitudes | Educational Change | Grade 6 | Grade 7 | Grade 8 | Semi Structured Interviews | Kruskal Wallis Test | Foreign Countries | Mixed Methods Research | Likert Scales | Social Studies | Turkey | Barriers | Teaching Methods | Teacher Characteristics | Statistical Analysis
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13. Navigating through problem solving and reasoning in grade 4
by Yeatts, Karol L and Litwiller, Bonnie H
2005, Principles and standards for school mathematics navigations series, ISBN 9780873535748, vi, 83
Problem solving in children | Fourth grade (Education) | Activity programs | Mathematics | Study and teaching (Elementary)
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14. Full Text No A 4 U: The relationship between multitasking and academic performance
by Junco, Reynol and Cotten, Shelia R
Computers & Education, ISSN 0360-1315, 09/2012, Volume 59, Issue 2, pp. 505 - 514
The proliferation and ease of access to information and communication technologies (ICTs) such as Facebook, text messaging, and instant messaging has resulted... 
Learning | Texting | Mobile phones | Multitasking | GPA | ICT use | Facebook | EDUCATION & EDUCATIONAL RESEARCH | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | CELL PHONE CONVERSATIONS | TIME | Cognitive Processes | Time Management | Regression (Statistics) | Computer Mediated Communication | Time on Task | Access to Information | Attention | Synchronous Communication | Computer Use | Grade Point Average | Student Surveys | College Students | Handheld Devices | Internet | Colleges | Talking | Students | Education | Strategy | Texts
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15. Full Text Under‐grading of <4 cm renal masses on renal biopsy
by Harris, Catherine R and Whitson, Jared M and Meng, Maxwell V
BJU International, ISSN 1464-4096, 09/2012, Volume 110, Issue 6, pp. 794 - 797
Study Type – Prognosis (case series) Level of Evidence 4 What's known on the subject? and What does the study add? It is well documented that biopsy of small... 
nephron‐sparing surgery | renal cell carcinoma | renal mass biopsy | Fuhrman grade | ablation | nephron-sparing surgery | UNITED-STATES | METAANALYSIS | CELL CARCINOMA | NEPHRECTOMY | PERCUTANEOUS BIOPSY | RISING INCIDENCE | UROLOGY & NEPHROLOGY | PROGNOSTIC-SIGNIFICANCE | MORPHOLOGIC PARAMETERS | EPIDEMIOLOGY | RADIOFREQUENCY ABLATION | Kidney Neoplasms - surgery | Neoplasm Grading | Nephrectomy | Carcinoma, Renal Cell - pathology | Humans | Middle Aged | Ablation Techniques | Carcinoma, Renal Cell - surgery | Female | Kidney Neoplasms - pathology | Male | Aged | Tumors
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